Effects of B and Cu additions on the microstructure and mechanical properties of high-strength bainitic steels were investigated in this study. Six kinds of high-strength bainitic steels with different B and Cu contents were fabricated by thermo-mechanical control process composed of controlled rolling and accelerated cooling. The microstructures of the steels were analyzed using optical and transmission microscopy, and the tensile and impact tests were conducted on them in order to investigate the correlation of microstructure with mechanical properties. Depending on the addition of B and Cu, various low-temperature transformation products such as GB (granular bainite), DUB (degenerated upper bainite), LB (lower bainite), and LM (lath martensite) were formed in the steels. The addition of B and Cu increased the yield and tensile strengths because of improved hardenability and solid solution strengthening, but decreased the ductility and low-temperature toughness. The steels containing both B and Cu had a very high strength above 1.0 GPa, but showed a worse low-temperature toughness of higher DBTT (ductile-to-brittle transition temperature) and lower absorbed energy. On the other hand, the steels having GB and DUB showed a good combination of tensile and impact properties in terms of strength, ductility, yield ratio, absorbed energy, and DBTT.