Objectives : Comparison acupuncture treatment with Acupuncture & Moxibustion combined treatment for frozen shoulder 20 case patients Methods : Efficacy evaluation using Apley scratch test(ROM), Martin.A.N'Improvement rate Results : 1. Acupuncture & Moxibustion combined treatment group were better than acupuncture treatment group in Martin.A.N' Improvement rate. 2. Acupuncture & Moxibustion combined treatment group were better than acupuncture treatment group in Apley scratch test(ROM). but this study need to many case frozen shoulder investigation.

Objectives : This study was designed to evaluate the clinical effects of herb medicine and acupuncture therapy on chronic bacterial prostatitis. Method : A clinical observation was made on two patients with chronic bacterial prostatitis diagnosed with DNA analysis. They were treated with herb medicine and acupuncture therapy. Before and after treatment we measured National Institutes of Health Chronic Prostatitis Symptom Index(NIH-CPSI) and WBC counts on expressed prostatic secretion(EPS). Results : According to DNA analysis, Streptococcus mitis and Veillonella was proved to be the cause for chronic bacterial prostatitis for each patients. After treatment, NIH-CPSI score improved from severe to mild, and WBC counts on EPS decreased considerably from many to under 10. Conclusion : The present result suggest that oriental medical therapy has effect on chronic bacterial prostatitis. Further clinical study about chronic bacterial prostatitis, and research on herbal medicine sensitive to each bacterium causing chronic bacterial prostatitis is needed.

以古今文獻爲中心, 對肺風粉刺進行硏究, 得出如下結果: 在 "黃帝內經"的"素問 生氣通天論"和"素問 氣交變大論"中, 首次言及虛勞與熱爲主的病因說. 言及以熱和風熱, 風熱與濕相搏爲主的病因說的著作是"千金方", "證治要訣", "證治準繩", "外科正宗", "諸病源侯論", "洞天奧旨"等. "證治準繩"更詳細地言及其病因, 卽認爲該病是飮食或金石劑等太過, 積熱聚於陽明經而發病. 對顔面部的發病, 古今醫統及諸多文獻都認爲與陽明胃經有關, 而且還與 脾肺有關. "外科正宗"指出風熱閉塞毛竅是其病理所在, 認爲肺風, 粉刺, 酒病鼻的病理相同, 但成爲發生原因的臟腑, 以脾, 肺爲主而各異. 陳士鐸在.洞天奧旨.中指出因肺熱與風導致氣血不和而發病, 且指出此病是靑春男女都.厭倦的疾患. "聖濟總錄"認爲該病是趁精氣虛之機, 邪氣侵入而發生. 而"醫學入門"認爲腎陰不足是發生該病的病機所在. "萬病回春"指出其病因是上焦火, 肺熱, 陽明經鬱熱, 提出治法是凊上降火.

歷代諸家以多種依據, 對"素問"的著者是否黃帝進行了論述. 李圭晙以兩個論點爲依據, 判斷了"素問"的著者. 根據孔子認爲黃帝通達生死之原因和草木之味說, 以及孔安國認爲存在伏羲, 神農, 黃帝等的三墳書之說, 判斷爲三墳書中所說的黃帝之著作, 卽爲現流傳之"素問". 李圭晙無師獨學者, 幷具有果敢地對儒敎之經典, 進行刪定的主觀性較强的人. 因此, 其閱讀"素問"後認爲,"素問"之內容深奧而精辟, 把天地陰陽之根源及死生由命的緣故和昆蟲草木的隱微等都進行論述, 故判斷爲此非聖賢所能爲之. 但是, 其亦認爲"素問"的整個內容, 幷不是黃帝的之全作. 認爲經過夏殷周三代, 其內容存在刪改及缺漏引起的前後之矛盾之處, 而且漢代以後亦有錯簡及訛傳. 尤其經王冰對"素問"進行整理, 以及高保衡等的重新校正, 其根本才被分辨出來. 見到諸多醫者不學"素問", 且以"素問"爲依據主張錯誤觀點, 導致生命之寃亡. 因此, 如同刪定儒敎等經典一樣, 對醫學之經典"素問"進行了刪定, 幷稱爲"素問大要".

We came to the conclusion as follows from the research about pulse diagnostic technique (脈診) out of "Nan Jinghoeju jeonjung" (難經滙注箋正). 1. "Nan Jing" is practical medical book for clinician and holds different opinions about three portions and nine takings(三部九候脈法) from Huang Di Nei Jing's Taking the pulse of Bu Jung Chim Chon Kwan Chuk((浮中沈 寸關尺) is a quite creative means which has been a important role to future generation. 2. We pointed the differences between western medical science and traditional medical science. And can explain the pulse in western medicine divided from twelve channels of Oriental Medicine. We can explain special connection between heart and lungs using the theory of systemic & pulmonary circulation in western medicine. And this can be a basement of Lung controls every pulse theory in oriental medicine. 3. We have negative assertion about viewing the human body using theory of Yin and Yang-Five Elements. And have poor opinion of explaining about the matching internal organs to Chon Kwan Chuk using the theory of Yin and Yang-Five Elements. 4. We pointed out the mistake that Porak & Sang hwa act for heart. We took pulses considering heart is a real actual internal organ as others. 5. We denied the theory of Man's Chuk pulse is always weak(男子尺脈恒弱) & Woman's Chuk pulse is always strong(女子尺脈恒盛). The physical form of man and woman is not different from each other considering their inheritances from forefather & same shape of organs. So, we cannot insist on the theory.

張山雷是淸末及民國時期人. 他學而不厭, 幷窮醫之理, 他所作的著作除了"難經.注箋正"以外, 還有許多有著作. 其中"中風斠詮" 最爲著名. "難經滙注箋正"分爲匯注和箋正兩個部分, 匯注卽滑壽和徐與靈胎寫的"難經本義" "難經經釋"爲主, 箋正卽張山雷寫自己分析各注家的理論的內容或批評各家之錯處, 還有寫自己的意見. 張山雷主張不恰當的陰陽五行偏見應該廢止, 而且後世醫者衍文添字以後變成爲其原來的眞義. 他認爲宋朝以後醫者已經認識五行學說的理論所以添字而附會. 古代的陰陽五行理論比較單純, 一般描述天氣寒熱溫暖等情況. 可是"難經"的內容當中發現許多後代才完成的比較複雜的陰陽五行內容, 比如面色便色脈象的遲數等等. 此爲添字的最好證據. 另外, 多地方發現重複記述的誤謬, 一樣的名詞又有不一致的表現. 例如一邊稱腎主液, 另一邊稱腎主濕等等, 這種事情是不易了解的. 還有不合理的陰陽五行情況. 比如七傳, 心病卽喜苦味, 肝行氣於左等等. 在"難經滙注箋正"張山雷一直主張正名正解而防弊弄假作虛.

Chang San-roe re-explained the contents from the 30th question to the 47th question of "Nan Jing" which refered to the Chang-Pu and physiological theories as follows through the western theory which wss different from the tranditioonal chinese theory 1. "Nan Jing" refered to the circulation and the coming into being of Yeong-Wi. He denied that it was classified Yeong from Wi or Eum from Yang. 2. He denied that Sam-Cho was separated to three parts and the theory of "Sam-Cho is name only, not shape", using western medical theory. 3. He denied the view about "Left side is kidney, right side is Myung-Mun" because it was incorrect that kidney was separated to two parts which were Su and Hwa or Eum and Yang 4. Re-explaining the contents of "Nan Jing"- the portions of heart and lungs, the rising and falling of liver and lungs, the relationships of five viscera and sound color smell taste fluid, the relationships of five viscera and nine hole, the relationships of five viscera and O-Chu, the physiological difference of the old and the young owing to the deflection of Yeong-Wi Chi-Heol- he thought that viewing the human body using theory of Eum and Yang, Five elements(五行) was a far-fetched interpretation, so he denied the tranditional chinese theory which understood human body's organs, physiology, pathology. 5. He explained the contents of "Nan Jing"- the portions of the colon and the small intestines, the funtion of the six bowls, the corespondence of Chang-Pu, physical peculiarity of liver, the anatomical aspects which were the sizes, weights, volumes and shapes of the Chang-Pu and the alimentary canal, Chil-Chung-Mun, Pal-Hoe-Hyeolthrough western anatomy and physiology in detail.

通過對"難經滙注箋正"中兪穴的硏究, 得結論如下: 張山雷主張在十二原穴中陰經的原穴是兪穴, 在六腑中另有原穴, 而原穴是主治五臟六腑之疾患的. 因此, 認爲三焦是指人體上中下三部, 而不是指手少陽三焦經. 其主張五輸穴的運行似水之流動, 故與五行配屬是不對的. 尤其是認爲六陰經的井穴配屬於木及六陽經的井穴配屬於金是不對的, 但是張山雷自身對其道理亦難道明. 對"本輸"中出現的十二原穴與"難經”的相差處進行了說明, 在"甲乙經”指出了手少陰心經的五輸穴, 所以推測皇甫謐的參考文獻資料更爲確切. 綜上所述, 筆者對張山雷的主張旣有認同, 又有反對意見, 亦有無法判斷之處. 認爲張山雷對古人的未得到實證的理論試圖進行論證的實事求是的精神, 是値得我們學習的榜樣.

This study aimed to investigate the effects of Sesami Semen on the itching and anti-allergic inflammation mechanism related with cytokine, chemokine, histamine, $\beta$-hexosaminidase, NF-$\kappa$B, and free radical, and it was concluded as follows : 1. Sesami Semen did not show any cytotoxicity at the range of con-centration (1-250 ${\mu}g/m\ell$) on the human fibroblast cell (hFCs). 2. Sesami Semen reduced the gene expressions of IL-8, TNF-$\alpha$, IL-6 mRNA comparing with control. 3. Sesami Semen reduced the levels of IL-6, IL-8, MCP-1 within THP-1 cell depending on the concentration, and especially significantly reduced the the levels of IL-6, MCP-1 at all the concentration. 4. Sesami Semen significantly decreased the histamine secretion on HMC-1 at all the concentration. 5. Sesami Semen decreased the $\beta$-Hexosaminidase secretion 6.2% at 10 ${\mu}g$/ml conc., 58.3% at 100 ${\mu}g$/ml conc. and 63.2% at 200 ${\mu}g$/ml conc., respectively. And IC50 (${\mu}g$/ml) was 158.25 ${\mu}g$/ml. 6. Sesami Semen significantly suppressed the activity of NF-$\kappa$B promoter depending on the concentration. 7. Sesami Semen decreased the production of reactive oxygen species (ROS) and DPPH generation depending on the concentration. As judged with above results, the effects of Sesami Semen on the anti-allergic inflamation would be recognized, and it could be applied on the medicinal sources for prevention or treatment of several allergy disease. And more studies are needed furthermore with the seperation of effective materials.

This study saw the anti-allergy effect by the immunity regulation action of Yanghyelyoonbotang (YHYBT) consists 12 kinds of herbal medicine agents. Consequently, YHYBT controlled the amount of secretion of various infla- mmatory cytokines, chemokine, monocyte chemotactic protein and histamine from cells (HMC-1, THP-1, EoL-1) stimulated by PMA, A23187 or HDM. 1. YHYBT did not show cytotoxicity on cultured human fibroblast cells under 250 ${\mu}g/m\ell$ concentration. 2. YHYBT suppressed IL-8, TNF-$\alpha$, IL-6 mRNA expression in the HMC-1 cell stimulated with PMA and A23187. 3. YHYBT significantly suppressed IL-6 release in the THP-1 and EoL-1 cell stimulated with HDM. 4. YHYBT significantly suppressed histamine release in the HMC-1 cell stimulated with PMA and A23187 in a dose-dependent. 5. YHYBT significantly suppressed $\beta$-Hexosaminidase release in the HMC-1 cell stimulated with A23187 in a dose-dependent. 6. YHYBT suppressed NF-$\kappa$B gene expression in the RBL-2H3 cell stimulated with PMA in a dose-dependent. These results suggested that YHYBT has suppressive effects on allergic reaction and pro-inflammatory cytokines in various cell lines through the regulation of immune system. YHYBT has potential to use as an antiallergic agents.

Sophorae Radix (SFR) is known as a therapeutic drug that has been used in Oriental traditional medicine for the treatment of skin and mucosal ulcers, gastrointestinal hemorrhage, diarrhea, inflammation and arrhythmia. In the present study, we examined the effects of the aqueous extract of SFR on anti-inflammation, anti-allergic and anti-oxidant effect in various cell lines; they include mouse lung fibroblast cells (hFCs), human mast cells (HMC-1), human monocytic cells (THP-1), and RAW 264.7 cells. Treatment with SFR extract at a concentration of 250 ${\mu}g$/ml for 24h showed no significant decrease in the survival rate of the hFCs. SFR decreased the mRNA expression of IL-8, TNF-$\alpha$, and IL-6 in HMC-1 cells. SFR extract treatment significantly inhi-bited the protein expression of IL-6 and, IL-8 induced by mite in THP-1 cells and it also did MCP-1 expression. We examined the alternation of histamine release in HMC-1 cells for investigating anti-allergic effect of SFR. Histamine secretion decreased after the treatment with SFR. In addition, SFR extract treatment at a concentration of 10 ${\mu}g$/ml, 100 ${\mu}g$ /ml, and 200 ${\mu}g$/ml lowered the $\beta$-hexosaminidase to 10.3%, 21.7%, and 50.8%, respectively. IC50 of SFR extract in RBL-2H3 cells was 196.85 ${\mu}g$/ml. Both activity of NF-$\kappa$B promoter in RBL-2H3 cells significantly diminished after the dose-dependent treatment of SFR. Therefore, our results indicate that SFR has anti-inflammatory and it may be useful for treating allergic diseases such as atopic dermatitis.

Objectives : This study is in order to contribute in straight dietary intake to paient and people through Oriental medicine literary investigation. Methods : Contents from 20 classical texts is investigated by importance, control, notice of Dietary intake. Results : Oriental Medicine regard control of dietary intake for important medical treatment.

간암은 전 세계적으로 발병률이 높은 암 중 하나이며 매년 5만 명이상이 간암에 의하여 사망하고 있으며, 특히 한국과 중국 그리고 아시아의 다른 국가들에서 매우 높은 사망률을 보이고 있다. 따라서 본 연구는 간암치료에 있어서 한 중간의 한의학적 교류와 이해를 도모하기 위해 병인(病因), 병기(病機), 변증논치(辨證論治), 다용처방, 민간요법, 한약의 적용, 침 보안요법, 간섭치료 등 최근 중국에서 시행되고 있는 다양한 임상적 치료방법을 고찰하였다.

간섬유화는 다양한 만성 간질환에 기인하는 간실질의 결합조직의 과도한 증식을 말하며, 간경화로 발전하는 중간과정이다. 중국과 한국에는 많은 간섬유화 환자가 있지만 현재까지 서양의학에서 간섬유화를 효과적으로 치료할 수 있는 치료법은 발견되지 않고 있다. 최근 수년간 중국전통의학의 임상과 실험연구에서 많은 발전이 있었다. 전통의학이론을 바탕으로 활혈거어(活血祛瘀), 익기(益氣)의 효능이 있는 한약제가 항섬유화 효능을 보였다. 전통중국의학에서 간섬유화에 대한 일반적인 치료는 유효 성분, 단방 및 복방 처방의 세 부분으로 나뇐다. 우리는 중국전통의학에서 간섬유화의 효과적인 치료와 관련된 작용기작을 소개하였다.

Peripheral axons in vertebrate animals can regenerate after nerve injury and accomplish its functional recovery. Numerous studies have revealed that diverse molecular factors are induced during axonal regeneration and their potential roles in axonal regeneration have been studied. Examples is N-CAM, L1, P0, nerve growth factors, GAP-43 and so forth. However, most of the studies on axonal regeneration have been primarily focused on axon fiber regrowth and elucidating molecular factors, and relatively less is known about functional recovery. Also, specific drugs or drug components used in the oriental medicine in relation to nerve fiber regeneration have not been known. And thus, in the present, a study on the effect of Yukmijihwang-tang components and Yukmijihwang-tang extracts to regeneration of peripheral axon fiber is underway by immunofluorescence staining. Therefore, this prior application of Yukmijihwang-tang with documents consideration is reported with a plea for further investigation.

Objective : Atopic dermatitis is a prevalent disease. Taeyeol-go(TYG) is a herbal ointment which was expected to useful for treatment of atopic dermatitis. The aim of this study was to evaluate the effect of TYG on atopic dermatitis. Methods : Patients with atopic dermatitis applied TYG twice daily for 1 week. Clinical extent, intensity and subjective symptom were assessed by scoring atopic dermatitis (SCORAD) index before and after treatment. Results : 10 patients(4 male, 6 female), 3 to 37 years of age(mean 14.6${\pm}$9.52 years old), 2 to 31 years of onset(mean 11.4${\pm}$8.54 years), finished study. After treatment extent(p<0.01), intensity(p<0.005), subjective symptom(p<0.002) and total SCORAD index(p<0.002) was significantly decreased than before treatment. Conclusion : These results suggest that TYG is an effective therapeutic method for atopic dermatitis. Further studies in the form of randomized controled trail are needed.

The literatural study on the effect of acupuncture for tinnitus was studied from the viewpoint of acupuncture effect. The conclusions are as follows. 1. The ear manages kidney, it relates with the heart meridian of hand soeum, kidney meridian of foot soeum, lung meridian of hand taeeum, spleen meridian of foot taeeum, stomach meridian of foot yangmyeong, gallbladder meridian of foot soyang, triple energizer meridian of hand soyang, small intestine meridian of hand taeyang. 2. According to classification of meridian in acupuncture treatment of tinnitus triple energizer meridian of hand soyang 18.0%, gallbladder meridian of foot soyang 16.6%, bladder meridian of foot taeyang 16.6%, small intestine meridian of hand taeyang 9.7%, large intestine meridian of hand yangmyeong 8.3%, stomach meridian of foot yangmyeong 5.5%, spleen meridian of foot taeeum 4.1%, pericardium meridian of hand gworeum 4.1%, lung meridian of hand taeeum 2.8%, heart meridian of hand soeum 2.8%, kidney meridian of foot soeum 2.8%, liver meridian of foot gworeum 2.8%, conception channel 2.8%, governor channel 2.8% have been used much in turn. 3. In the general points GB2 24times, TE3 22times, TE17 22times, SI19 20times, TE21 20times, KI 3 19times, BL23 17times, LI4 15times have been used much in turn.

Vulvodynia is the term used to describe unexplained vulvar pain, sexual dysfunction, and the resultant psychological disability. Vulvodynia may cause physical disabilities, psychological or emotional distress, sexual dysfunction and limitation of daily activities. But its etiologies and treatments are not defined yet. In vulvodynia, the first method of treatment is conservative treatment. surgery is carried out on patients who have failed consevative therapy. In conservative therapy, the rate of improvements is low, 30-40%Surgical procedures are effective in almost patients, but the efficacy is not known in patients with the riskiness. This study is designed to find best way of evaluation about the vulvodynia.

Objective: This study was to investigate the effect of oriental medical treatment for Structual scolosis. Methods: This patient has scoliosis was treated with Herbal medicine, acupuncture and chuna therapy. And we evaluated the case with radiological measurement by calculating the scoliosis correction angle. Results: After the treatment, the cobb'angle of T-spine was changed 15" to 3". Conclusions: We report the good result of oriental medical treatment on this case. The more study of oriental medical treatment for Structual scolosis is needed.

In oriental medicine, Zingiberis Rhizoma Recens & Jujubae Fructus are frequently used materials for the digestive system, outer harmful qi(外感) and dam-yeum(痰飮). Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun(方藥合編), Zingiberis Rhizoma Recens is used 3pyun(片)(4g) and Jujubae Fructus is used 2mae(4g). The most important fact is that, in contrast to most people know that chyranthis Bidentatae Radix & Jujubae Fructus are used most prescription at the same time, the prescription used chyranthis Bidentatae Radix & Jujubae Fructus at the same time is merely 77. (Bang-Yak-Hap-Pyun percentage of Zingiberis Rhizoma Recens & Jujubae Fructus is 16.48%). The number of prescription Zingiberis Rhizoma Recens & Jujubae Fructus in Bang-Yak-Hap-Pyun is total 173. 42 in sang-tong(上統), 86 in jung-tong(中統), 45 in ha-tong(下統). The group of mostly used disease is about outer harmful qi(外感) and dam-yeum(痰飮). The ratio of Zingiberis Rhizoma Recens in Bang-Yak-Hap-Pyun is 3.70%~100%. And the ratio of Jujubae Fructus is 0.45%~29.14%. The mostly quoted medical literature what prescription included Zingiberis Rhizoma Recens & Jujubae Fructus in Bang-Yak-Hap-Pyun is Tae-Pypng-Ha-Jae-Guk-Bang.

In oriental medicine, Polygalae Radix & Acori Graminei Rhizoma are frequently used materials for the cardiac disorder(palpitaion), brain disorder(sleep disorder, forgetfulness, confused mind, dizziness). Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun(方藥合編), Polygalae Radix is usually used 1don(錢)(4g) and Acori Graminei Rhizoma is used 1don(錢)(4g). The most important fact is that, in contrast to most people know that Polygalae Radix & Acori Graminei Rhizoma are used most prescription at the same time, the prescription used Polygalae Radix & Acori Graminei Rhizoma at the same time is merely 3. (Bang-Yak-Hap-Pyun percentage of Polygalae Radix & Acori Graminei Rhizoma is 0.64%). The number of prescription Polygalae Radix & Acori Graminei Rhizoma in Bang-Yak-Hap-Pyun is total 16. 10 in sang-tong(上統), 4 in jung-tong(中統), 2 in ha-tong(下統). The ratio of Polygalae Radix in Bang-Yak-Hap-Pyun is 0.41%~14.28%. And the ratio of Acori Graminei Rhizoma is 4%~16.66%. The mostly quoted medical literature what prescription included Polygalae Radix & Acori Graminei Rhizoma in Bang-Yak-Hap-Pyun is Tae-Pypng-Ha-Jae-Guk-Bang.

Objective : To research the trend of studies about anti-allergic response on Herbal Acupuncture therapy by analysing domestic theses, published after 2001, about Herbal Acupuncture therapy. Methods : I reviewed and analyzed domestic theses, published after 2001, mentioning anti-allergic response of Herbal Acupuncture therapy. And these theses were classified by university, year, field of study, subject. Results : In theses focusing on anti-allergic effect, there were some cases trying to prove remedial value of operating herbal acupuncture on acupuncture points, and cases trying to prove its effect on immunity.

In oriental medicine, Rhei Radix et Rhizoma & Gardeniae Fructus are frequently used materials for anti-inflammatory effect especially urinary tract disease and for neuropsychosis. Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescription book. In Bang-Yak-Hap-Pyun(방약합편), Rhei Radix et Rhizoma is used 0.8g~16g. and Gardeniae Fructus is used 1.2g~6g. The most important fact is that the prescriptions used Rhei Radix et Rhizoma & Gardeniae Fructus at the same time are 4(Yang-Gyuk-San, Pal-Jung-San, Sa-Chung-Hwan, Suk-Gyul-Myung-San. The ratio of Rhei Radix et Rhizoma & Gardeniae Fructus are 2:1, 1:1, 1:1, 1:2 ). The number of prescription Rhei Radix et Rhizoma & Gardeniae Fructus in Bang-Yak-Hap-Pyun is total 45. 1 in sang-tong(上統), 5 in jung-tong(中統), 39 in ha-tong(下統). The group of mostly used disease is about urinary tract. The ratio of Rhei Radix et Rhizoma in Bang-Yak-Hap-Pyun is 3.33%~57.14%. And the ratio of Gardeniae Fructus is 3.47%~98%. The mostly quoted medical literature what prescription included Rhei Radix et Rhizoma & Gardeniae Fructus in Bang-Yak-Hap-Pyun are Dong-Yi-Bo-Gam and Man-byung-hoe-chun.

Purpose Brain vessles have autoregulation function, so even when perfusion pressure drops, cerebral blood flow remain stable by vasodilation. Latest research on this reserve of cerebral vessels is being done using TCD, which measures the reserve of the vessels. We did a research comparing cerebral vessel and peripheral vessel reserve between Taeumin, who are more likely to suffer CVA, and the normal. We observed blood flow of Internal carotid artery siphon and radial indicis artery of the two group with TCD. Method We picked 20 people out of patients diagnosed as cerebral infarction at Cheon-An Oriental hospital of Daejeon University. They were diagnosed as Taeumin with QSCCII questionnaire and constitutional differentiation. Using TCD, we measured highest blood flow rate, mean blood flow and asymmetric counting blood flow of Internal carotid artery siphon and radial indicis artery at rest. And then we measured again after stimulating cerebral vessels, by triggering hypercapnia by self apnea and peripheral vessels by palm heating. Result At rest, mean blood flow rate of Internal carotid artery siphon showed significant decrease compared to control group. Blood flow rate of Internal carotid artery siphon after hypercapnia showed significant decline in highest blood flow rate and mean blood flow compared to control group. Cerebral vessel reaction after the hypercapnia induction showed great change in experiment group than the control group. Peripheral vessel reaction after palm heating showed significant decline in experiment group compared to control group. Conclusion In conclusion, measuring the alteration of blood flow used in diagnosing cerebral infarction, is more sensitive when vessel stimulation is done. Non-invasive TCD is effective especially in case of Taeumin who are more likely to suffer vascular disorder than others.