In order to investigate the effects of YOOKMIJIHWANGTANG, GAMIJIHWANGTANG and PALMIJIHWANGTANG on the various immune responses, the chemotactic, adherent, nitric oxide release ability of macrophages were studied in vivo and in vitro. The results obtained were follows : 1. The total number of peritoneal exudate cells from mice injected with three drugs were 2~3 times more than those from the PBS. 2. The administration of three drugs enhanced significantly the Fc receptor mediated activity(phagocytosis, rosette formation activity). 3. The administration of three drugs enhanced significantly the chemotactic activity of peritoneal macrophages. 4. The administration of three drugs enhanced significantly the adherent activity of macrophages and neutrophils. 5. The administration of GAMIJIHWANGTANG and PALMIJIHWANGTANG enhanced significantly the chemotatic activity of macrophages (p<0.01). And also the administration of YOOKMIJIHWANGTANG enhanced significantly the chemotatic activity of macrophages(p<0.05). 6. The administration of GAMIJIHWANGTANG and enhanced significantly the chemotatic activity of neutrophils(p<0.01). And also the administration of YOOKMIJIHWANGTANG and PALMIJIHWANGTANG enhanced significantly the chemotatic activity of neutrophils(p<0.05). From above findings, it is suggested that YOOKMIJDTWANGTANG, GAMIJIHWANGTANG and PALMIJIHWANGTANG seems to produce the increase of immune response such as the Fc receptor activity, chemotactic activity, adherent activity, nitrate release of macrophages. From the above results, the GAMIJIHWANGTANG among three drugs may be the most useful drug having immunostimulating effects.

This study was undertaken to identify the degree of burden and depression according to level of self-care activity and variables to which affect that in family caregivers of patients with stroke. The data were collected from October 23th to November 20th, 1995 The subjects in this study were 80 caregivers, that is, one family member and 80 patients with stroke who were hospitalized in one oriental medicine hospital in D city. The questionnaires consisted of questions regarding burden(13 items, 6 point scale), depression(20 items, 4 point scale), and self-care activity(15 items, 5 point sacle) Data were analyzed using percentages, means, t-test and ANOVA with the SAS program. The results of this study are as follows: 1) The mean score for client's self-care activity was 2.58. The highest score of the self-care activity item was 'returning'(M=3.604), and the lowest score of the self-care activity item was 'shower or tubbathing'(M=1.925). 2) the degrees of self-care activity according to the general characteristics of patients were tested. It was significantly different by sex(P<0.01), occupation(P<0.05), and relationships with patients(P<0.05). That is, the degree of self-care activity was higher in men than that of women, and caregiver with job than caregiver without that. In the case that caregiver was a patient's spouse, the degree of self-care activity was higher than other case. 3) The score for family caregiver's burden was higher than the mid level for the 13 items and caregiver's depression was relatively low. 4) According to the degree of self-care activity, the group was divided to 3, that is, A( 15-33), B(34-56), and C(57-75). The score of total burden was the highest in group A(M=55.257) and the lowest in group C(M=51.928), but there were no statistically significant differences between groups. The score of objective burden was the highest in group A(M=30.400), and the lowest in group C(M=25.214), and there were statistically significant differences between groups. The score of subjective burden was the highest in group B(M=26.000) and the lowest in group A(M=24.783), but there were no statistically significant differences between groups. The degree of depression was the highest in group A(M=44.750) and the lowest in group C(M=40.751), but there were no statistically significant differences between groups.

Most of cancer therapy consists of surgery, chemotherapy and radiotherapy developed by modern western medicine. Often Korean patients use both modem western and oriental medicine through their cancer life. This study tried out to answer the the question : "What are the experience of a Korean cancer patients who follow oriental medicine after cancer diagnosis?" To answer to that, a micro-ethnographic research method was used. Total 6 patients were observed from March, 1996 to February, 1997. Data were obtained through interview, participant observation, audio-tape recording, field recoding, field note-taking, and ralated documents Using an analytical tool known as "pencil and scissors", the data were analyzed. First, I learned patietnts' accounts for cancer experience following oriental medicine, and I could found that they expereinced "feeling of uncertainty" through cancer life. Second, major argument was searched. : Feeling of uncertainty of cancer patients was extremely increased after cancer diagnosis. Oriental Medicine made cancer patients not only expect to improve general physical condition, but also gave them significnat emotional support to overcome their feeling of uncertanty. Third, I examined how did this argument form meanings in the context of individual life. Modem western mediacal service system could not satisfy cancer patients' informational and emotional need. But oriental medicine contribute to relieve the degree of their feeling of uncertainty. As a result of these understandings, I suggest that modern wetern medicine need to be concerned to feeling of uncertainty of cancer patietns and infomational service, and oriental medicine counsel with cancer patients much more systemically. Also nurses must improve cancer education with more accurate and practical information based on empirical data.