By studying the portions and layers(分部), left and right, superior and inferior, location of yin and yang, and beginning and end of diseases of skin, which is the core point of the theory of cutaneous region(皮部論) in "Naejing(內經)", in the physiological and pathological perspective, based on opinion of historic memorial doctors, arrived to the conclusion as below. Cutaneous region means not only the distribution of three yin and three yang(三陰三陽) of the surface, but also inside and outside, shallowness and depth, and it is the system which unites meridians, networks, and vessels. It is divided into portions and layers. The origin and beginning of diseases and the rule of favorable pattern and unfavorable pattern can be known through it. The portion of skin is not only the area that meridian vessels belongs to skin, but also the area that activation of twelve meridian vessels are expressed in the surface. The layer of skin is consisted in order of skin-tertiary collateral vessel-collateral vessel-meridian vessel-bone. In "Naejing", there are two preconditions to divide three yin and three yang into yin and yang. The first is standing while looking the south, and second is the quotation "outside is side of yang(外者爲陽 內者爲陰)." According to this preconditions, yang of outside of yang brightness, lesser yang, and greater yang is the whole body, except inside of hand and foot which yin of lesser yin, pericardium, and greater yin. Superior and inferior of the portions and the layers is designated as hand and foot, theological basis of which superior and inferior work in same diagnostic method can be found in the root and the basis(標本) and the origin and the insertion(根結). In conclusion, cutaneous region not only manages layer of the skin, but also it is divided into layers and portions, so it has close relations between meridian vessels and collateral vessels. The in-depth study of cutaneous region and meridians should be progress, in order to practice of diagnosis and acupuncture and moxibustion more.

Systemic Lupus Erythematosus(SLE) is an autoimmune disease invading the skin, joint, kidney, intestinal membrane, neurosystem and other organs. SLE is an autoimmune disease characterized by immune dysregulation resulting in the production of antinuclear antibodies(ANA), generation of circulating immune complexes, and activation of the complement system. In Korean medicine, lupus can be classified as acute arthritis, reddish butterfly erythema, asthenic disease, edema and so on. The cause and procedure of the diseases are flourishing noxious heat, excessive fire due to deficiency of yin, blood stasis due to stagnation of qi, internal movement of the liver-wind, congenital deficiency, exhausted vital-qi, which are treated by clearing away heat and cooling the blood, nourshing yin and extinguishing fire, treating flatulence and activating blood circulation, nourishing the blood to expel wind, invigorating the liver and kidney, invigorating qi and replenishing the blood. To experimentally examine the influence of Insam-Buja-Tang (Ginseng & Aconiti Extract, IBT) on the outbreak and development of lupus, lupus induce MRL/MpJ-Faslpr lupus-prone mice model was used. As IBT was orally administrated to a lupus model mouse, various tests such as the weight, urine protein, renal function, Lymph cell test of the spleen, Cytokine expression, histopathological analysis of kideny were performed to see the influence on the kidney and whether it work effectively on the immune function. The main purpose of this study is to evaluate the effect of IBT on MRL/MpJ-Faslpr lupus-prone mice model. The effect of IBT on MRL/MpJ-Faslpr lupus-prone mice that can have autoimmune disease similar to SLE in human was evaluated after IBT per oral in the present study.

It fuses into culture of the East and the West in use of color ; colors of five direction, which had been from the Five Phase Theory in East Asia. Formative ability of color fields in a formative early Oriental Medicine history as well. Color is a very important factor and a necessary step of visible diagnosis. As a human's body is maintained and alive under the control of spirit and spirit is stored by five viscera, so spirit expresses the change of five viscera and is reflected by color. Visible diagnosis consists of spirit, appearance, Qi and color and movement. The purpose of each visible diagnosis is that we would know states of essence, Qi and spirit in patient's body. To ancient Asia people 'to see' was a kind of insight to the object as a whole. Similarily the activity of seeing the human body was the integral part of making diagnosis of a patient. This was the cause that there was suggested the discussion of the Five color theory in Oriental Medicine as a counterpart to that of the 'Goethe for Zur Farbenlehrer'. The inspection of Oriental Medicine was not a simple gazing of the eye as a sense organ, but the total insight to the internal state of the patient. For that reason, the eye－perception in early Chinese medicine was the reading the signs of the internal body which had have not the visual form but the flux of the internal life.

In western, aromatherapy uses essential oils to prevent and treat disease, and is one of the ways to stay healthy. In oriental medicine, there was also a similar medical treatment using aromatic herbs for a long ago. The exisiting research of oriental medical herbs is mainly focused on the theory of qi and flavor(氣味論). But on aromatherapy used with aromatic herbs, it is necessary to study the aromatic herbs by aroma. So "xi$\bar{a}$ng p$\check{u}$, 香譜" and "b$\check{e}$n c$\check{a}$o g$\bar{a}$ng m$\grave{u}$, 本草綱目" mainly contain the study about clinical effects of aromatic herbs. And "b$\check{e}$n c$\check{a}$o p$\check{i}$n hu$\grave{i}$ j$\bar{i}$ng y$\grave{a}$o, 本草品彙精要"mainly explains the effects of medical herbs with five aroma classification of x$\bar{i}$ng(腥), sh$\bar{a}$n(膻), xi$\bar{a}$ng(香), ch$\grave{o}$u(臭), xi$\check{u}$(朽). The former one makes more clinical uses of medical herbs, and the latter one grows up the theory of medical herbs. This study is expected to have a good influence on aromatherapy and classification of oriental medical herbs.

There are two methods in inspection diagnosis(望診), the viewing shape(觀形) and the inspecting color(察色). Acquiring proper analysis from viewing shape(觀形) requires several standards of shape that can be compared with. We can identify major defects and flaws of the shape from comparing it with the standards that is defined as very normal shape. Also, It can eventually provide us interpretation of health related meanings of the objective shapes. Those standards need symmetrical and proportional details. In this research, I put some physiognomy and inspection diagnosis related documents, and standards for restorative plastic surgery together to suggest standards on viewing shape diagnosis of nose which is one of the most important spot in facial inspection. It is expected to improve delicacy of Oriental medine's inspection diagnosis, as the result of the comparison between plastic surgery and inspection diagnosis.

A Case of dizziness treated with Singi-hwan is reported. Singi-hwan is an herbal formula historically used for Jing(精) deficiency in Traditional Korean Medicine and dizziness is a common symptom presented in patients with Jing(精) deficiency. An elderly patient diagnosed with senile dizziness was treated using Singi-hwan for ten consecutive days in Dunsan Oriental Hospital, and has shown positive outcome.

Objectives: This study aimed to investigate the effects of Amyda sinensis (AS) on allergic inflammation mechanism related atopy dermatitis. Methods: To investigate the effects of AS, We study inhibitory effect of AS on the levels of pro-inflammatory cytokines released from Raw264.7 cell stimulated with LPS (lipopolysaccaride), and EoL-1, THP-1, Jutkat cell stimulated with DP (Dermatophagoides pteronyssinus), and LPS indused acute inflammatory BALB/c mouse model. Result: AS reduced the levels of IL-$1{\beta}$ released from Raw264.7 cell stimulated with LPS at 20 ug/ml, 5 ug/ml concentration, and reduced the levels of IL-6 in a dose-dependent. AS significantly reduced the levels of MCP-1 released from EoL-1 cell stimulated with DP (Dermatophagoides pteronyssinus) at all the concentration, and significantly reduced the level of IL-8 at 0.1 ug/ml concentration. AS significantly reduced the levels of MCP-1 released from THP-1 cell stimulated with DP (Dermatophagoides pteronyssinus) at 1 ug/ml concentration, and reduced the level of IL-6 in a dose-dependent. AS significantly reduced the levels of IL-4 released from Jutkat cell stimulated with DP at all the concentration, and significantly reduced the level of IL-5 at 0.1 ug/ml. 1 ug/ml concentration,. and reduced the level of TNF-${\alpha}$ in a dose-dependent. AS significantly reduced the levels of TNF-${\alpha}$, IL-6, IL-$1{\beta}$, in LPS indused acute inflammatory BALB/c mouse model, in a dose-dependent. Conclusion: These result suggested that AS has suppressive effect on pro-inflammatory cytokines in various cell lines through the regulation of immune system. AS could be applied on the medicinal sources for treatment of immune abnormal diseases such as atopy dermatitis afterward.

Hyperhidrosis is common complication of spinal cord injury, but localized unilateral hyperhidrosis is relatively rare disorder without autonomic disreflexia. A 52-year-old man with a 10-month history of cervical injury induced tetraplegia complained of excessive intermittent left-sided sweating. The sweating occurred by urinary retention or without any autonomic dysreflexia. The patient sweated excessively on the left face and upper body. In the point of Differentiation of Syndrom (辨證), the patient was diagnosed as Gi-Heo-Hyeol-Eo (Pi-Wei-Qi-Xu 氣虛血瘀) and was administered revised Boyanghwano-tang (reserved Bu-Yang-Huan-Wu-tang), and he was almost complaint free during 4 month about none dysreflexial hyperhidrosis.

Background : Although chronic non-bacterial prostatitis is increasing, it is hard to treat effectively. In western medicine, antimicrobials drug, ${\alpha}$-adreno-ceptor antagonists, anti-inflammatory drugs, tricyclic antidepressants and anticholinergic agents are used commonly, but chronic prostatitis/chronic pelvic pain syndromes is confusing and frustrating for urologist. IDS(Indongsoyeom-bang) is used in treatment of chronic prostatitis/chronic pelvic pain syndromes. And it is reported that GLS(Gleditsiae spina) and TOF(Toosendan fructus) components of IDS have significant effect on protection of the glandular epithelial cells. Objective : In this study was conducted to investigate the therapeutic effects and action machanism of IDS in the rat model of non-bacterial prostatitis induced by castration and testosterone treatment. Methods : We observed six experimental objects of normal group, control group, testosterone group, and IDS 50 mg/kg, 200mg/kg, 400mg/kg group. Rats were treated with 17 ${\beta}$-estradiol after castration for induction of experimental non-bacterial prostatitis, which is similar to human chronic prostatitis in histophatological profiles. IDS and testosterone were administered as an experimental specimen and a positive control, respectively. The prostates were evaluated by histological parameters including the epithelial score and epithelio-stromal ratio for glandular damage. Also, the prostates were observed by Hematological alterations of WBC, RBC, hemoglobin and platelet. Results : While prostates of control rats revealed severe acinar gland atrophy and stromal proliferation, the rats treated with IDS-50 showed a diminished range of the tissue damage. Epithelial score was improved in IDS than that of the control. The epithelio-stromal ratio was lower in IDS when compared to that of the control. Also, the examination of bloods were not observed hematological change. Conclusion : These finding suggests that IDS may protects the glandular epithelial cells. We concluded that IDS could be a useful remedy agent for treating chronic non-bacterial prostatitis.

Purpose: This paper is aimed to report the effects of Gamiguibitang on the Climacteric Syndrome. Methods: A patient who had been suffering from Climacteric symptoms was enrolled in this study. She received oriental treatment such as herbal medicine for 3 months. We gave her Gamiguibitang five times. During the treatments, we requested her to visit hospital twice a week. If she could not come to hospital, we called her to take follow-up. Results : After oriental medical treatments, several symptoms of Climacteric Syndrome were improved. Conclusion: This clinical case indicate that Gamiguibitang is effective in treatment of the Climacteric Syndrome. More clinical data and studies are requested for the treatment of Climacteric Syndrome Patient.

Purpose: This paper is aimed to report the effects of oriental medicine on general pain after childbirth Methods: Two patients, 35 years old and 33 years old, who had a general pain after childbirth, were enrolled in this study. They received oriental medicine for several months. During the treatments, we gave them Gamikunguitang(加味芎歸湯) 2 times, each for 3 weeks. we check changes of symptoms. Results: After the oriental medicine treatments, symptoms of general pain after childbirth and other symptoms were decreased or disappeared. Conclusion: This clinical cases indicate that Gamikunguitang(加味芎歸湯) is effective in treatment of the general pain after childbirth progress and relapse of symptoms. More clinical data and studies are requested for the treatment of general pain after childbirth.

Objective : This study is to investigate the effect of Yukmijihwangtang Gamibang on Male Acne patients. Methods : We treated 3 male acne patients diagnosed as the deficiency of Yin with Yukmijihwangtang Gamibang and comedon extraction. After treatments We compared the before and after photos, and estimated by Korean Acne Grading System(KAGS). Results & Conclusions : After taking Yukmijihwangtang Gamibang, extruding comedones by needle and appling acupuncture, the acne was improved. This study shows that the acne can possibly be diagnosed as the deficiency of Yin. So further studies are needed continuously.

Objectives : The purpose of this study was to investigate the effect of treatment with Sacro-Occipital Technique block on musculoskeletal pain caused by traffic accident by analysis of the Visual Analogue Scale(VAS), Neck Disability Index(NDI), Pain Disability Index(PDI), Oswestry Low back Pain Disability Index(ODI) and Short Form - McGill Pain Qusetionnaire (SF-MPQ). Methods : This study carried out on 18 patients who have received hospital treatment in Daejeon Univ. Dun-San Oriental Hospital. Control group got acupunture-therapy, herbal medication, physical therapy and Experimental group got all the therapies and treatment with Sacro-Occipital Technique block. We measured VAS, NDI, PDI, ODI and SF-MPQ on 1st day and 7 days later. Results : After being treated by our methods, Both group were improved in VAS, NDI, PDI, ODI, and SF-MPQ. Especially, Experimental group was significantly meaningful improved in VAS, PDI, and ODI. Control group was significantly meaningful improved in VAS and SF-MPQ. But, differences between control and experimental group were nonsignificant. Conclusions : The results suggest that treatment with Sacro-Occipital Technique block is not significantly meaningful but gives a positive impact on musculoskeletal pain caused by traffic accident. But further long term study in a large scale is needed.

Objective : The purpose of this study was to review on the need for early screening of scoliosis. Methods : We have researched and analyzed theories and literatures of scoliosis screening program. Result : The following results were obtained in this study. 1. Scoliosis screening should be carried out to improve middle and high school students's health and learning abilities. 2. The methods are the forward bending test, Moire test and X-Ray. 3. After the examination held by differentiating the degree of scoliosis, surgery or brace treatment for students should be carried out. 4. After the examination, appropriate acupuncture, exercise therapy and orthodontic treatment for students should be carried out. 5. Spinal health courses for young people should be held regularly to equip and encourage a healthy body and healthy mind and contribute to improve the learning efficiency. Conclusion : Scoliosis screening and early detection should be done in the Daejeon city middle school or high school students, and appropriate treatment should be performed as soon as possible.

Objectives : This study is to research the trend of the oriantal medical treatment for tinnitus and to establish the hereafter direction for the study on oriantal medical treatment for tinnitus. Methods : We reviewed the domestic articles published last eleven years(2000- 2010). Results : We have searched 21 articles in 5 journals of korean oriental medical ophthalmology &dermatology, korean acupuncture & moxibustion, korean oriental medicine, oriental physiology & pathology, sasang constitutional medicine. 1. There were the most research done 2006. They have 5 articles. In other years there were 3 or less articles. 2. The pattern of study was as follow: the consideration of documents were 5, clinical trials were 6, case studies were 8 and the others were 2. the rate of case studies were increased. 3. After mid 2000s, there were more studies of new research method appearing. Conclusions : The oriental medical treatment already effective for tinnitus. But we need more studies about various kind of oriental medical treatment for tinnitus.

Objective : The objective of this study is to observe the effect of Pharmacopuncture of Anti-inflammatory Herbal compound(AiC) theraphy on elbow pain Methods : The patients diagnosed as lateral epicondylitis and treated mainly with Anti-inflammatory Herbal compound(AiC). After the application of herbal acupuncture, The NRS and ROM of elbow were assessed. Results & conclusion : Symptoms of the patient such as elbow pain and dysfunction were improved after above treatments. so, it is suggested that oriental medical treatment(Pharmacopuncture of Anti-inflammatory Herbal compound(AiC)) is effective on Tennis elbow.

Objectives : This paper researched methods of washing Herb medicine through research papers of washing Crops Materials and Methods : We collected research papers on Washing crops. Then we analysed them according to washing methods. Results : The following results were obtained in this study. 1. Herbal fruit, wash using a conveyor belt. 2. Leafy herbs, soak in a chlorine solution or ozone solution and rinse it. sometimes using micro bubble system. 3. Radix, wash with high pressure sprinkling water. 4. Cortex, wash under running water by hand washing. Conclusion : Herb medicines need a washing methods for each region. so Herbs should be washed in a suitable methods for each region.

This study aims to summarize and make a reference of Sagunjatang and Samultang by investigating and comparing the effects of prescriptions. In this process, this review surveyed all papers used Sagunjatang and Samultang in PubMed database and finally 36 papers were included. The publication year, the nations of authors, the type of materials, the formation of experiments, the type of herbal medicine, and their action and mechanisms were analyzed. The number of studies on Sagjunjatang and Samultang has increased since 1990's. The main formation of experiments was in vivo study and the portion was 55%. The proportion of the research using prescriptions was 71%. Sagunjatang was investigated in the field of GI track function, anticancer effect, radioprotective effect and etc. Samultang was studied in the field of anticancer effect, brain cognitive function, anti-inflammatory effect, cell protective effect, and etc. Based on these results, Sagunjatang and Samultang showed the different bioactivities. This study will provide the useful information on differentiation and analysis of the effect of herbal prescriptions by the theory of Korean traditional medicine.