Learning can be defined as its objects, main question for the objects, and its unique way to organize all the knowledge acquired as the results of the question. From the point of view like this, Traditional Korean Medicine(TKM) can be defined as learning for human body and its functions, health and diseases based on the theory of the Yin and Yang and of the five elements. Nowaday Many papers based on laboratory work publish for the name of scientization of TKM, but from the viewpoint of definition of learning, they have a problem that there is no basic theory. If TKM could be communicated with western natural science, it has to be solved. And oriental physiology has a same object and same questions with western physiology, so oriental physiology can be useful to make a bridge between TKM and western natural science.

Objectives : The anti-inflammatory and antioxidant effects of water extracts of Sasangja-tang(SSJ) and Gami-sasangja-tang(GSJ) were investigated. The effects of SSJ and GSJ were compared. Methods : We performed cell viability assay in HaCaT cells and RAW 264.7 cells using 3-(4,5-dimethylthiazol-2-yl)-2, 5 diphenyltetrazolium bromide(MTT) assay. We measured chemokines(regulated on activation normal T-cell expression and secreted ; RANTES/CCL5, interferon-inducible protein; IP-10/CXCL10, macrophage-derived chemokine; MDC/CCL22) in HaCat cells, also we measured cytokines (tumor necrosis factor-${\alpha}$; TNF-${\alpha}$, interleukin-6; IL-6) and nitric oxide(NO) production in RAW 264.7 cells using enzyme-linked immunosorbent assay(ELISA) and NO assay. Western blot assay was used to evaluate the expression for inducible nitric oxide synthase(iNOS) in RAW 264.7 cells. Results : SSJ and GSJ did not affect the cell viability at the concentrations treated ($0-800{\mu}g/ml$). As a result of SSJ and GSJ treatment in HaCat cells stimulated by TNF-${\alpha}$(10 ng/ml) and interferon(IFN)-${\gamma}$(10 ng/ml), the production of RANTES and IP-10 was inhibited significantly. However there was no significant difference in the secretion of MDC. And in RAW 264. 7 cells stimulated by lipopolysaccharide(LPS, $1{\mu}g/ml$), SSJ and GSJ treatment significantly inhibited the secretion of TNF-${\alpha}$ and IL-6 and the production of NO. The expression of iNOS was also decresed by SSJ and GSJ treatment in RAW 264. 7 cells. Compared with SSJ, GSJ was superior to SSJ in inhibition of RANTES, IP-10, TNF-${\alpha}$, IL-6 and NO production at the concentration of $200{\mu}g/ml$. Conclusion : Both SSJ and GSJ have anti-inflammatory and antioxidant effects. And GSJ has better effects than SSJ.

Objective : The purpose of this study is to demonstrate the characteristics of pulse diagnosis in infertile women. Methods : We have studied 38 women infertility patients in the Dunsan oriental hospital by using pulse diagnostic device. Pulsation and pulse types have been analyzed with variables of infertility factors. Statistical analysis was performed by adopting descriptive and inferential tests. Results : Both right and left chi parts were shown different from other parts. In small intestine and gall bladder showed significantly different pulsation according to the infertility factor. Short pulse, fine pulse, skipping pulse, shallow pulse and deep pulse were often representative pulse types for the main organs of woman infertility. In Triple energizers showed significantly different shallow pulse type according to the infertility factor. Conclusion : The results corresponded closely with previous literature on pulse diagnosis about infertile women.

Objective : The purpose of this study was to examine the level of the cognitive function, and to identify the influencing factors on cognitive function in women cancer patients receiving chemotherapy. This study attempted to provide basic data useful to development of nursing intervention and improve the quality of life in women cancer patients. Methods : As a cross-sectional descriptive study, women with receiving chemotherapy above one cycle were recruited. One hundred and twenty-five women cancer patients who met the study criteria agreed to participate in the study. The questionnaire set consisted of cognitive function, quality of life, depression, anxiety and information on demographic and clinical characteristics. Results : There was no statistically significant difference in clinical characteristics according to the cognitive function. The cognitive function was higher the more low age (F=9.937, p<.001), and the more high education level (F=12.332, p<.001). Multiple regression analysis showed the predictors were significantly related to cognitive function. age, education, and the number of chemotherapy explained 31.8% of the cognitive function. Conclusions : This result of this study provides basic information about factors influencing cognitive function, although study findings are insufficient in explaining related variables among women cancer patients. Even though women cancer patients were receiving chemotherapy, this study showed that the level of cognitive function was high. In order to receive better results and findings the period decreasing cognitive function, further studies are need to measure cognitive function according to the passage of time during or after chemotherapy.

The purpose of this study was to report the effect of Bogijetong-tang on post-herpetic neuralgia(PHN). The main symptoms were numbness, pain, burning, paresthesia on left dorsum pedis and insomina. We prescribed Bogijetong-tang (BJT) three times a day and performed acupuncture and moxibustion twice a day. We observed the change of symptoms to evaluate the therapeutic effect. The symptoms were evaluated with numerical rating scale(NRS). After the treatment, pain decreased from 8 to 3, burning from 5 to 1, paresthesia from 7 to 5, numbness from 5 to 3 and insomina improved. Above the results, Bogijetongtang is effective in treating post-herpetic neuralgia.

2010년 2월 3일~ 2014년 12월 3일까지 본원에서 입원 및 외래치료한 기존 치료에 불응성 2형 당뇨병 환자에 한약, 침치료를 가하여 증상개선과 함께 혈당 강하 효과를 보여 주어 당뇨병에서의 한방치료의 가능성을 확인하였다.

Object : This study is designed to confirm the effect of Traditional korean Medicine on oculomotor nerve palsy patient. Method : We treated with acupuncture therapy, electro-acupuncture therapy, herbal therapy, physical therapy, moxibustion therapy. And we evaluated a patient's eyelid ptosis, eyelid levator function, eyeball movement, eyeball pain. Result : After Traditional korean Medical treatment, ptosis and pain caused by ophthalmoplegia were improved. Conclusion : This study shows Traditional korean Medicine has a good effect on oculomotor nerve palsy.