정자 운동의 분석은 붙임의 원인 규명과 진단에 중요한 정보를 제공한다. 본 논문에서는 연속된 정자 운동 영상을 이용해 정자 운동성의 주요 척도인 선형속도, 곡선속도, 선형성, 운동력등의 운동특성을 검출해 내는 알고리즘을 구현했다. 비디오 신호로 보내진 정자 영상을 컴퓨터에 의해 디지털화하고, 각 정자 머리의 위치를 계산해내었고, 이로부터 정자 등의 경로 및 주요 운동특성를 찾았다.

화학적 이동성을 이용하여, 생체의 경우 지방질의 영상 혹은 물성분의 영상을 얻을 수 있다. 여러 가지 기술을 사용하여 분리된 성분의 자기공명 영상을 얻었다. Dixon의 방법은 두 번의 영상실험을 하여 지방질 영상과 물성분 영상을 구분할 수 있으며, 부분적 자기장의 불균질성에 영향을 적게 받고 다층 영상법에 용이하게 적용할 수 있다. CHESS와 SECSI 방법은 한번의 영상실험으로 물 또는 지방질 영상을 획득할 수 있다. 그러나 부분적 자기장의 불균질성에 영향을 많이 받으며, 다층영상법에 적용하기에는 어려운 점이 있다. 화학 성분의, 즉 지방질과 물성분의 분리의 척도가 되는 지방질 신호대 물성분신호 비에 있어 SECSI 방법이 가장 우수함을 보였다.

Texture analysis, one of the mage processing techniques, using statistical characteristics is applied to the ultrasound images, which are then classified into each types through neural network. This is a method to be used to diagnose ultrasound images automatically and objectively. First tone kinds of texture analysis techniques proposed already are used to classify ultrasound images and compared in terms of classification rate, and then a new technique if proposed which is invariant to multiplicative gain changes and image resolution.

We examine the compression performance of two irreversible (lossy) compression techniques, ADCT-VQ (Adaptive Discrete Cosine Trandform - Vector Quantization) and JPEG (Joint Photographic Experts group) which are basis of medical image information systems. Under the same compression ratio, MSE(Mean Square Error) is 0.578 lower in JPEG than in ADCT-VQ while SNR(Signal to Noise Ratio) is 1.236 dB higher in JPEG than in ADCT-VQ.

Color Doppler flow mapping (CDFM) was performed on an $\underline{in\;vitro}$ experimental setup with a regurgitant moving orifice using the proximal isovelocity surface area (PISA) technique. PISA flow rates underestimated actual flow rates by as much as 65%, which is very important in diagnosing patients with valvular regurgitations or stenosis. The correction factor considering the velocity of the orifice improved the PISA flow rates.

$\underline{In\;vitro}$ velocity measurements were made using both the pulsed Doppler ultrasound (PDU) machine and laser Doppler anemometer (LDA) system in order to investigate the flow characteristics near the aortic bifurcation. Velocities measured from the PDU machine was in good agreement with those from the LDA. The flow in the daughter branches was three-dimensional with a secondary flow. The oscillating wall shear stress with this secondary fluid motion is well correlated with the localization of the atherosclerosis.

This paper describes pattern classification algorithm of ECG using back-propagation neural network. We presents new feature extractor using second order approximating function as the input signals of neural network. We use 9 significant parameters which were extracted by feature extractor. 5 most characterized ECG signal pattern is classified accurately by neural network. We use AHA database to evaluate the performance ol the proposed pattern classification algorithm.

In this paper, we quantitatively evaluated the anxiety data from humans in an anxiety state. It has been reported that the electric signals of human can be correlated with their emotional state. We chose heart rate, respiration rate, temperature and skin conductance as the anxiety parameters. For experiment protocol, the subject was given exercising load to induce the anxiety state and the exercise was done using the FITRON Cycle Ergometer. We divided the data into three stages: rest period, exercise period, and recovery period. During evaluation, We counted the heart rate, slope of heart rate, temperature change, and the skin conductance.

Hybrid optical-electronic procedures are introduced for the automated estimation of cell parameters (e.g., size, size variation, and shape). Two different optical Fourier analysis procedures are applied to high contrast cell boundary patterns obtained from specular micrographs of the endothelial layer. In one case, a large number of cell patterns are illuminated to extract average cell size information. Once the average cell size information has been obtained, individual cells are illuminated to extract shape information.

흉부 X선 영상을 판독함에 있어서 중요한 정보중의 하나로 폐실질의 조직 특성이 이용된다. X선 영상에서 뼈 혹은 심장, 굵은 혈관등은 X선의 투과율이 적어 시각적으로 밝고 균일한 재질로 나타나며, 공기가 채워져 있는 폐실질은 어둡고 산소/이산화탄소 교환에 관계되는 미세한 조직들에 따라 균일하지 않은 재질로 나타나는 특성을 보이고 있다. 본 연구에서는 공간적인 주위조직의 경보를 이영하여 현지의 부분을 예측하여 인식하도록 수정된 경쟁 순환 신경망을 이용하여 흉부 X선 영상에서의 순수한 폐실질 부위를 영역 분할한다.

We have designed the speech signal processor for cochlear prosthesis using quadrature mirror filter (QMF). And it is real-time implemented using DSP macros TMS 320C30.

In this study, Fuzzy control algorithm to generate a change of rocomotion cordition according to an outer environment is introduced on a motorized wheelchair control. An optimal control rules for conquesting the less of safety and system inefficiency in the past are given to this motorized wheelchair. And dynamic analysis is also adopted to it. Using those rules, a proportional control was possible when the vehicle changed its moving direction. The proposed method which considers the relationship between a moving velocity and the command from the joystick shows better performance in the change of moving direction.

In this study, the PSD and coherence spectra of electroencephalogram are estimated us ins multichannel AR model. This enables us to perform the topographic mapping of EEG by interpolation.

Under the assumption that the EMG signal was used as the reference signal for driving a prosthetic arm, function discrimination of EMG signal from the biceps and triceps of subject was achived with LPC CEPSTRUM coefficients. By varying the number of coefficients, the types of windows, window size, and window overlaping rates, the best conditions for the function discrimination of EMG signal were obtained.

In this paper, the Infant Incubator Consisting of amp lifer, A/D Convert, I/O Expand, Watchdog Timer, Alarm Circuit. Display, and mirco-Computer part was developed. The care of Premature new borns of the required that they be in an environment in which temperature is elevaled and Controlled, because they are unable to regulated their own temperature. The central and processing methods based on micro-processor employ the flexibility, and economy over other conventional system. The system characteristic were as follows 1) system based on micro-processor. 2) Easy-to read, touch-Operate control panel all displays and indicators 3) System flexibility.

The sensory nerve study is the important index to diagnosis peripheral neuromyotic disease. This paper discusses about the design of parameter - latency, amplitude, conduction velocity - measurement system in the sensory nerve. This system consists of three parts which are Main Control Unit(MCU), Stimulator, and external output unit. Also new measurement algorithms which is adaptive threshold method is presented in this paper. The designed system is controlled by MCU includes automatic detection algorithms and self-diagnostic functions.

The object of this research is to develop the autobalancing system based-on microprocessor for hemodiafiltration(HDF). The results obtained from the proposed system are as follows: (1) Conventional HD system is not proper for removal medium molecular articles but HDF is proper when this autobalaning system is interfaced. (2) we can get mere exact information than conventional HD system using electronic balancemeter.

After development of order communication system for out-patients using PC and LAN in May 1992, this system had been tested for 2 months. The system also use Host computer(IBM 9221-170) as a data bank and communicats wi th emulation card(3270 emulator. Interlink Inc., Korea). Since September 1992, this system(named YOUSEI-PC) has been running successfully in the Yonsei Cardiovascular Center of the Severance Hospital, Yonsei University College of Medicine. After introducing this system, it enables patients to receive drugs wi thin 30 minutes after prescription and revealed effective system not to reduce waiting time for the patients but also to remove charge-troubling(due to mis-entry of prescription). This system also seems to be effective in terms of office automatism for hospital management. However users, usually physitions, required more friendly and easy system to operate and we thought that the most important one to successfully introduce order communication computer system in the hospital is user interface.

Currently, detection of sacroilitis is necessary in detect ion of ankylosing spondylitis. So early detection of sacroilitis is needed for early detection of ankylosing spondylitis. But it is difficult to detect sacroiliac abnormalities in early stage by conventional plain X-ray. Therefore, it is performed 3-dimensional volume rendering from the CT image of sacroiliac. Then early detection of sacroilitis is made by analyzing the reconstructed 3-dimensional image.

Automatic transmission of data from the blood analyzer to the request site is one of the most important part in hospital computerization. We have developed a system to automatically transmit the data from the atrial blood gas analyzer. In this system, HOST computer, FILE server, LAN(Local Area Network), 3270 Emulator and Multi-port card were integrated. Also, 3 blood gas analyser(NOVA Inc., USA) were connected to a single multi-port card which is attached in a personal computer for data acquisition. When specimen is collected from sampling sites, it is transfered to the lab. After analysis, the result is transmitted to the personal computer via serial communication between machine and multi-port card using interrupt method. Then, the patient's information (Name, Sex, etc.) is obtained from the HOST computer througth the emulator. The combined data(patient information & lab data) is transmitted to the each request site via LAN automatically. From the collected data, patient's previous data could be reviewed, and it could be used for the various statistics and the flow chart for clinical research. Also, we found that this system reduces the personal labor.

In this paper, we have implemented the telemedicine system which has a color image system and a biosignal processor. The inputted image is acquisited to 512 by 480 color image data. The col looted data is compressed to 1/5 of the original image data by using 1/5 and compression algorithm. A biological signals are inputted by 12 bit A/D converter into the system. In case of using 2400bps modem, a frame full color image data and biological information data needed 10 minutes in transmission.

In systems in which inductive coupling between a pancake-shaped coil on the surface of the body and a similar coil within the body is utilized for the transfort of electromagnetic energy, the minimization of temperature rise in the tissue is intimately related to the achievement of minimum losses in the region of the implanted coil. The new class of amplifiers, named "class E", for inverter is defined and is illustrated by a detailed description and a set of desist equations for one simple member of the class. For TET circuit the authors measured 65 to 76 percent efficiency at 1985kHz at 30 to 50 W output from IRF250 MOSFET transistor.

In this paper, we describe about control system for eletro-hydraulic LVAD(Left Ventricular Assist Device) and control algorithm for two operation mode. One is asynchronous operation mode and the other is synchronous operation mode synchronized with natural heart's R pulse. We also present implementation method of software PI algorithm for velocity control of motor used in LVAD system and its response.

In this paper a new cardiac output control method without pressure sensors is presented for the rotor-driven totally implantable TAH using motor-current wavelet analysis. Theoretical analysis and mock circulation system experiment results show that cardiac output of TAH, which is indeperdent of afterload and sensitively dependent to preload, is well controlled for the independently variable preload.

심부전 환자의 심근회복을 도울 수 있는 장비인 전기유압방식 좌심실보조기를 개발하였다. 좌심실보조기는 혈액펌프, 압력펌프, 제어기로 구성되어 있으며, 혈액펌프에 내장된 혈액주머니는 동물실험을 위하여 50 ml의 크기로 제작하였다. 좌심실보조기의 성능평가를 위하여 최대 박출량을 측정하고 있으나 실험실에서 측정된 간은 동물 실험에서 관찰되는 것보다 일반적으로 증가된 박출량을 보이게 된다. 이는 생체에서는 좌심방의 체적이 박동 주기에 따라 변하여 좌심실보조기가 받아들일 수 있는 유효 혈액량이 변하는 반면, 모의순환장치에서는 좌심방을 단순 저장고로 사용하기 때문에 좌심방의 박동주기에 따른 체적변화를 감안하지 못하여 생기는 것이다. 본 실험에서는 모의순환 장치에 체적변화 가능한 100ml 크기의 좌심방을 연결하여 좌심방으로 들어오는 혈류량이 제한된 동물실험 상황을 모방하였다. 좌심실보조기의 제어방식중 수측기 이완기 비율(SD 비율)변화에 따른 좌심방 음압발생효과를 관찰한 결과 SD 비율을 40 %로 유지하면 행정거리가 클때도 좌심실의 음압발생을 줄일 수 있는 것을 관찰하였다.

The cardiac depolarization model using three dimensional ventricular model is simulated. To study this theme, we constructed a cardiac ventricular model and simulated the cardiac activation process using the action potential duration and the activation time. The cardiac potential model is generated by the logical combination of the elliptic equations. The action potential duration could be obtained from the fact that it is linearly distributed between model cells. The cardiac activation process was simulated by the law of "all-or-none". Based on the activation time and the action potential duration the cardiac potential at the arbitrary time after the activation of the model cell was computed. To test the validity of model, the comparison the results of model simulation with the physiological data was performed.

표면에 여러 가지 기능성기를 가지는 microspheres는 immunoassay, drug delivery system, cell separation등 의용공학분야에 응용이 기대되고 있다. 이들 분야의 응용을 위하여 유화제를 사용하지 않으면서, 기존의 회분식, 반회분식, seed 중합법등의 문제점을 극복한 two stage shot growth technique올 개발하여 여러 가지 기능성기가 표면에 도입된 microspheres를 제조하였으며, 응용의 전단계로서 이들 microspheres에 대한 모델 단백질(BSA)의 흡착실험을 pH, 기능 성기의 종류와 양, BSA농도를 변수로 행하여 최대 흡착량을 보이는 조건을 결정하였다.