• 대한간호학회지
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• 제3권2호
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• pp.121-132
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• 1973

Introduction : Nursing as a profession is gelling wide acceptance today, especially among independent -minded women with necessary physical, mental and academic qualifications. This is particularly true of "comprehensive nursing", which requires to total dedication on the part if the nurse herself-physical, mental and sociocultural. Such comprehensive approach is like-wise called for in the institutional training of professional nurses. Undergraduate nursing courses nowadays place an increasing emphasis on the microscopic approach of training a nurse as an intelligent and well-balanced human being with an optimum degree of cultural sophistication. Greater attention then ever before is now paid to close observation of the individual traits and aptitude of nursing students, so as to permit full development of individual capabilities, interests and propensities within the concept of "comprehensive human education. " Purpose of study 1. To determine the degree of understanding of the part of nursing students of the various aspects of the subject taught in undergraduate nursing course. 2. To determine the motivation of nursing students in choosing the profession and possible subsequent change or attitude and outlook in the course of under graduated studies, as a means of presenting a new practical approach in nursing training based on the concept of "comprehensive human education. " Problems of study 1. The environments of nursing training will impinge on individual nursing students with different psychological impacts from lower to upper classes of under graduated studies. 2. Educational environments will have varying psychological impacts on students: a. Difference in religious faith among students. b. Difference in campus environments. c. Difference in domestic (family) circumstances. d. Difference in innate capabilities of students, 3. The understanding and attitude of individual nursing students towards the science of nursing will Have a close correlation with their respective motivations in choosing-nursing as a profession, and will also be closely influenced by the peculiarities of the subject taught, tile campus environments, etc, Delimitations of the study 1. Two universities offering 4-year nursing courses were selected. Due to the limited number of potential subjects, the optimum conditions of sample collection could not be fulfilled. 2. Subjects were confined to two classes in each university (sophomores and seniors) but without regard to the ages or scholastic achievements of individual students. 3. The conclusions derived from this study should be limited in application to the subject groups covered by the present study: they should not in any event be extended or applied to other groups. Procedures 1. Subjects: 40 nursing students each from the sophomore and senior classes of the "Y" and "K" universities situated in Seoul, aggregating 160 students altogether. 2. Instruments: Use has been made of questionnaires on (1) family backgrounds and (2) general information concerning. 3. Statistical Method: The findings of the present survey have been subjected to critical analysis as to the means, percentages, Cgi squares (X), standard deviations and the significance of the difference in means. Findings 1. Nursing students have chosen their subject of study with a confident outlook towards their future in society. 2. Horsing students have the necessary abilities to complete the prescribed courses of study. 3. The campus life of nursing students has been judged as very constructive, not with-standing certain in adequacies in the available educational facilities and the shortages of teaching staff. 4. The achievement levels of nursing trainees varied greatly according to their respective educational environments as well as their school years. 5. Clear and definite distinctions were discernible between the two universities as regards certain aspects of this survey, while no signifiant difference was observed in other: a. Sophomores and seniors in both universities gave nearly identical answers to questions concerning (1) motivation in choosing nursing as a profession, and (2) the way of spending leisure hours. b. Both universities revealed similar respective differences between sophomores and seniors as regards the abilities of fulfilling academic requirements ill the basic subjects. c. Educational environments have been found to be somewhat superior in the "Y"university to those of the "K" university, particularly as regard general campus and dormitory conditions. d. The high degree of dissatisfaction with the faculty, found in both universities, was considered to be a consequence of the universal phenomenon of "brain drain" and the relative neglect of the "comprehensive approach"in education.

• 대한간호학회지
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• 제5권1호
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• pp.93-111
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• 1975

As the hospitalized patients will be facing new stress situation due to change of his environment from home to hospital it will be very important to understand the psychological stress experienced by hospital patients not only for helping patients in the process of recovery from illness but also fulfil1ing the objective of comprehensive nursing care by understanding the needs of the patients. There is no doubt that it would be very helpful for treatment of patients as well as for improvement of nursing care if we know more about psychological needs of patients and give them adequate support to meet these needs. The study to find out the causes and degree of stress events experienced by hospitalized patients, with the objective of instituting improvement of nursing care program based on the needs of patients, was conducted during the month of September 1974 with 60 patients randomly selected from those admitted to medical and surgical wards at Yonsei Medical Center in that period The questionnaire form included 36 questions which are considered to be stress events for hospital patients, and was devide into five areas namely, such events related to 1) disease itself, 2) hospital environment, 3) nursing care and treatment, 4) communication and human relations, and 5) family and economic problems. The results of the study were as follows: 1. It was confirmed that hospitalization considered to be a stress producing factor and most patients perceived the admission to hospital as a stress factor. 2. According to the rating scale, it was found that degree of perceived stress shows a variation according to the source of stress producing event. 3. No significant differences in the mean values were observed statistically with the perceived stress levels according to demographic and other variables of patients related to hospitalization. 4. Among the questions related to disease itself, "Admission for surgery" was perceived most frequently as a stress event (97.14%) by patients. 5. With regard to the questions related to hospital environment, "death of the patient room-mate" was the most serious stress event perceived by patients (90%) and "living with hospital regulations"was considered to be less serious stress event (23.33%). 6. As for the questions related to nursing care and treatment, "limitation of freedom" was perceived as a stress factor most frequently (70.91%) by the patients and "worry for wrong treatment" turned out to be less frequent stress event (50.0%). 7. As for the questions related to communication and human relations, "difficulty to meet doctors when wanted"appeared to be the most frequent stress event by the respondents (75.86%) , followed by "no explanation about treatment or examination"(75.0%) and "no explanation about nursing care procedures"(71.66%). 8. With regard 111 tile questions related to family and economic problems, "inadequate finances for family living due to hospitalization"and "high cost of hospitalization" were the most frequent cause of stress mentioned by the patients. (80.0%). 9. As a result of application of the stepwise regression analysis, it was found that about 89% was explained by those events associated with disease itself, hospital environment and family and economic problems. By adding those events related to "nursing care and treatment" and "communication and human relation", 100% of stress associated with hospitalization was explained.

• The Korean Journal of Physiology and Pharmacology
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• 제19권5호
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• pp.389-399
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• 2015

Zinc has been considered as a vital constituent of proteins, including enzymes. Mobile reactive zinc ($Zn^{2+}$) is the key form of zinc involved in signal transductions, which are mainly driven by its binding to proteins or the release of zinc from proteins, possibly via a redox switch. There has been growing evidence of zinc's critical role in cell signaling, due to its flexible coordination geometry and rapid shifts in protein conformation to perform biological reactions. The importance and complexity of $Zn^{2+}$ activity has been presumed to parallel the degree of calcium's participation in cellular processes. Whole body and cellular $Zn^{2+}$ levels are largely regulated by metallothioneins (MTs), $Zn^{2+}$ importers (ZIPs), and $Zn^{2+}$ transporters (ZnTs). Numerous proteins involved in signaling pathways, mitochondrial metabolism, and ion channels that play a pivotal role in controlling cardiac contractility are common targets of $Zn^{2+}$. However, these regulatory actions of $Zn^{2+}$ are not limited to the function of the heart, but also extend to numerous other organ systems, such as the central nervous system, immune system, cardiovascular tissue, and secretory glands, such as the pancreas, prostate, and mammary glands. In this review, the regulation of cellular $Zn^{2+}$ levels, $Zn^{2+}$-mediated signal transduction, impacts of $Zn^{2+}$ on ion channels and mitochondrial metabolism, and finally, the implications of $Zn^{2+}$ in health and disease development were outlined to help widen the current understanding of the versatile and complex roles of $Zn^{2+}$.

• 한국수정란이식학회:학술대회논문집
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• 한국수정란이식학회 2002년도 국제심포지엄
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• pp.118-118
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• 2002

Programmed cell death (PCD) is thought as a well-controlled process by which unwanted cells are selectively eliminated. During the last decade many researches have elucidated molecules and their interactions involved in cell death by using largely in vitro induction of cell death or survival signals in a more defined manner, While these critical information and novel findings provide us with clearer understanding of mechanisms underlying cell death, it does by no means explain how PCD occurs and which cells or tissues are affected during normal embryonic development in vivo. In this study, we used zebrafish to examine whether the PCD is occurring selectively or randomly in developing embryos by whole mount in situ TUNEL analysis with specific markers for neural cells. The result revealed that the degree and distribution of TUNEL staining varied considerably throughout gastrulation stage, and there was also a number of TUNEL-negative embryos. Most of TUNEL-positive cells were scattered randomly throughout the blastoderm. During the gastrulation stage about 75 % of the embryos analyzed exhibited more than 5 TUNEL-positive cells. As the dorsal epiblast begins to thicken rather abruptly near the end of gastrulation, TUNEL-positive cells were mainly located along the dorsal side. Although there were some variations in TUNEL staining during segmentation and pharyngeal stages, TUNEL staining continued to be localized to the central nervous system, and was also detected in the sensory organs, trigeminal ganglions, and the primary sensory neurons. High levels of the cell death in developing brain between 20-somite and prim-6 stages are thought to play a role in the morphogenesis and organization of the brain. At prim-16 stage, cell death is considerably reduced in the brain region. Dying cells are mainly localized to the prospective brain region where ectodermal cells are about to initiate neurogenesis. As development progressed, high levels and more reproducible patterns of cell death were observed in the developing nervous system. Intensive TUNEL staining was restricted to the trigeminal ganglions, the primary sensory neurons, and sensory organs, such as olfactory pits and otic vesicles. Thus, PCD patterning in zebrafish embryos occurs randomly at early stages and becomes restricted to certain region of the embryos. The spatio-temporal pattern of PCD during the early embryonic development in zebrafish will provide basic information for further studies to elucidate genes involved in. regulation of PCD largely unknown in vivo during vertebrate embryogenesis.

• 한국가정과교육학회지
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• 제18권3호
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• pp.61-79
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• 2006

본 연구의 목적은 제7차 가정 교육과정에 대해 CIPP모형을 적용한 상황과 투입을 평가하여 차기 가정과 교육과정의 발전에 기여하는데 있다. 본 연구는 경상남도에 소재한 중학교 가운데임의 표집한 250 개교에서 제7차 교육과정 기술 가정교과의 가정 영역을 담당하고 있는 교사를 대상으로 설문지를 발송한 후, 응답 수집된 109명의 설문지를 최종 분석 자료로 사용하여 이루어졌다. 자료에 대해서는 SPSS 10.0 for Windows 프로그램을 이용하여 빈도, 비율, 평균, 표준편차를 산출하였다. 연구결과를 요약하면 다음과 같다. 첫째, 상황 평가(교육 상황 평가)로 보면 가정 교육과정의 교육목표와 성격에 대한 요구 조사에서 '진로탐색'에 대한 요구도가 높게 나타나고, '가정생활에 대한 이해를 높임'에 대한 요구도는 낮게 나타났다. 담당 교사의 자신감도 부족하지만, 교과에 대한 학생의 흥미와 관심도 낮은 것으로 나타났다. 둘째. 투입 평가(교육 계획 평가)로 보면 기술 가정 교육과정의 가정 영역에 대한 적절성에서 시간 배당, 내용 수준, 내용 분량에 대해 적절하지 못하다고 여기는 것으로 나타났으며 학교 수준에서 기술 가정 교육과정 구성과 교사의 수업지도안도 충실하게 이루어지지 않는 것으로 나타났다. 조사 항목 중에서 평가에 대한 학교 수준 계획 수립이 상대적으로 충실한 것으로 나타났고, 이에 비하여 교과 협의는 충실하게 이루어지지 않아 다양한 내용들을 제대로 협의하지 않는 것으로 나타났다.

• 마케팅과학연구
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• 제17권4호
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• pp.247-269
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• 2007

현대에 있어 동질적인 품질과 편익을 제공하는 제품을 가지고 다수의 기업들이 시장점유율 증대와 고객확보를 위하여 치열한 경쟁을 벌이고 있는 가운데 가격할인은 기업이 즐겨 사용하는 촉진수단이다. 가격할인은 단기적 매출향상, 소비자의 브랜드전환, 신제품의 시장침투 등의 목적을 달성하기 위하여 사용된다. 실제로 과거의 실증연구에 의하면 다양한 형태의 가격할인이 판매증대에 효과적이며 가격할인은 소비자의 지각가치를 증가시킨다고 하였다. 하지만 할인된 가격은 제품의 품질을 의심하게 하거나 낮게 평가하는 부정적인 효과가 있다는 사실이 밝혀졌으며, 모든 제품카테고리와 모든 구매상황에 대하여 가격할인이 소비자의 지각가치를 향상시킨다고 볼 수 없다. 이에 따라 본 연구에서는 브랜드애호도의 차이가 있는 제품을 대상으로 가격할인율에 따라 소비자의 지각가치에 어떠한 영향을 미치는지를 연구함으로서 브랜드애호도의 조절효과를 분석하였다. 브랜드애호도가 강한 제품에 대한 지각획득가치와 지각거래가치는 가격할인율이 낮을 때 보다 큰 경우에 증가할 것으로 예측하였으나 분석결과 유의적인 차이가 없는 것으로 나타났는데, 이것은 브랜드애호도가 강한 경우에는 가격할인에 의한 지각희생의 감소량이 크지 않았고 브랜드 자체에 대한 신뢰도와 속성에 대한 만족도가 높기 때문에 가격인하가 브랜드선택에 큰 영향을 미치지 않았다는 것을 의미한다고 할 수 있다. 반면 브랜드애호도가 약한 제품에 대한 지각획득가치와 지각거래가치는 가격할인율이 낮을 때 보다 큰 경우에 감소한 것으로 나타났다. 이는 브랜드애호도가 약한 경우에는 제품으로부터 획득하게 되는 편익에 대한 만족도와 신뢰도가 낮은데 이러한 특성을 고려해보면 가격할인이 클 때에 제품의 품질과 편익을 더욱 평가절하하거나 심리적으로 지각희생의 크기가 증가됨에 따라 지각가치가 감소되었음을 의미한다고 할 수 있다.

• 경영과정보연구
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• 제35권4호
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• pp.229-250
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• 2016

본 연구는 조직유효성에 영향을 미치는 요소 중에서 최근 이슈화 되고 있으며 심리학과 교육학에서 중시되어 다루어지는 주제인 공감(empathy)을 경영학에 접목시켜 직무스트레스라는 매개를 통해 조직유효성(직무만족, 이직의도)과의 관계와 연구의 한계점을 알아보고자 한다. 수도권을 중심으로 충청도, 경상도, 전라도 등을 포함한 5개 지역에 분포되어있는 기업 직장인들을 대상으로 설문조사를 실시하였고 결과는 spss 21 통계프로그램 사용하여 분석하였다. 본 연구의 결과 첫째, 공감의 하위요인 인지적, 정서적 공감 중에서 인지적 공감은 직무스트레스에서 부(-)의 영향을 미치는 것으로 확인되었다. 둘째, 공감의 하위요인 인지적, 정서적 공감은 모두 직무만족에 정(+)의 영향을 미치는 것으로 나타났다. 셋째, 공감의 하위요인 인지적, 정서적 공감에서 인지적 공감은 이직의도에 대해 부(-)의 영향을 미치는 것을 알 수 있으나 정서적 공감은 유의미한 영향을 미치지 않는 것으로 나타났다. 넷째, 직무스트레스는 직무만족에 부(-)의 영향을 미치며 이직의도에 정(+)의 영향을 미치는 것을 발견하였다. 마지막으로 공감과 직무만족 및 이직의도의 관계에 있어서 직무스트레스의 매개역할을 확인하였다. 이상의 실증연구결과를 바탕으로 연구의 의의 및 한계점, 향후 연구방향을 제시하였다.

• 한국산림과학회지
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• 제104권4호
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• pp.543-548
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• 2015

단목모수, 군상모수, 군상개벌, 대상개벌 등의 천연갱신 방법이 적용된 소나무림의 nSSR 유전변이를 조사하였다. 작업(벌채) 전 성목과 작업 후 임내에서 자연 발생한 1년생 치수들의 유전다양성을 비교한 결과 큰 차이가 없는 것으로 나타났으며(성목: A=13.4; $A_e$=4.3; $H_o$=0.596; $H_e$=0.598, 치수: A=13.6; $A_e$=4.3; $H_o$=0.571; $H_e$=0.597), 각각의 작업종에서도 통계적으로 유의한 차이를 발견할 수 없었다. 성목과 치수의 유전분화 정도는 매우 낮은 것으로 나타났으며($F_{ST}$=0.002), 각 작업종별 유전분화 정도 역시 낮은 값($$F_{ST}{\leq_-}0.01$$)을 보여 작업 전, 후 임분의 유전구조 변화는 크지 않은 것으로 추정되었다. 결과적으로 본 연구가 수행된 소나무 임분의 경우 유전다양성과 유전적 조성 변화에 미치는 천연갱신 작업종의 효과가 두드러지지 않은 것으로 나타났다. 그러나, 천연갱신 작업종이 유전변화에 미치는 영향을 보다 정확하게 평가하기 위해서는 작업 후 남겨진 개체(모수)의 교배로부터 발생한 치수들의 시계열적 유전변이와 유전구조 변화를 지속적으로 추정할 필요가 있는 것으로 판단된다.

• 대한감각통합치료학회지
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• 제9권1호
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• pp.1-9
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• 2011

목적 : 초등학교 고학년 학생의 장애아동에 대한 인식을 알아보는 것이다. 연구방법 : 연구 대상은 김해시에 소재한 통합교육을 실시하지 않는 초등학교의 4, 5, 6학년의 비장애 아동이었다. 연구 기간은 2008년 10월 2일부터 10월 17일까지였으며, 설문지를 사용하였다. 설문지의 하위 영역은 사귐, 활 동, 학업 영역의 세 부분으로 각 10문항으로 이루어져 있으며 SPSS 12.0을 사용하여 분석하였다. 결과 : 장애아동에 대한 인식조사 결과 첫째, 성별에 따른 인식은 남학생보다 여학생의 평균 점수가 높았으나 통계 적으로 유의미한 차이는 없었다. 둘째, 학년에 따른 인식은 4학년의 평균 점수가 가장 높았고 6학년이 가장 낮았으며 통계적으로 유의미한 차이가 있었다(F=3.546, p<0.05). 셋째, 장애인 접촉 유무에 따른 인식은 접촉 경험이 없는 학생이 있는 학생보다 평균점수가 높았으나 통계적으로 유의미한 차이는 없었다. 결론 : 비장애학생의 장애아동에 대한 인식은 학년에 따라 차이가 있었다. 본 연구는 작업치료사들에게 장애아동에 대한 또래집단의 인식에 대한 정보를 제공함으로써 학교환경에 대한 이해를 도울 수 있을 것이다.

• Journal of Korean Neurosurgical Society
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• 제65권6호
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• pp.834-840
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• 2022

Objective : C-reactive protein (CRP) level, erythrocyte sedimentation rate (ESR), and white blood cell (WBC) count are inflammatory markers used to evaluate postoperative infections. Although these markers are non-specific, understanding their normal kinetics after surgery may be helpful in the early detection of postoperative infections. To compliment the recent trend of reducing the duration of antibiotic use, this retrospective study investigated the inflammatory markers of patients who had received antibiotics within 24 hours after surgery according to the Health Insurance Review & Assessment Service guidelines and compared them with those of patients who had received antibiotics for 5 days, which was proven to be non-infectious. Methods : We enrolled 74 patients, divided into two groups. Patients underwent posterior lumbar interbody fusion (PLIF) at a single institution between 2019 and 2020. Group A included 37 patients who received antibiotics within 24 hours after the PLIF procedure, and group B comprised 37 patients who had used antibiotics for 5 days. A 1 : 1 nearest-neighbor propensity-matched analysis was used. The clinical variables included age, sex, medical history, body mass index, estimated blood loss, and operation time. Laboratory data included CRP, ESR, and WBC, which were measured preoperatively and on postoperative days (POD) 1, 3, 5, and 7. Results : CRP dynamics tended to decrease after peaking on POD 3, with a similar trend in both groups. The average CRP level in group B was slightly higher than that in group A; however, the difference was not statistically significant. Multiple linear regression analysis revealed operation time, number of fused levels, and estimated blood loss as significant predictors of a greater CRP peak value (r²=0.473, p<0.001) in patients. No trend (a tendency to decrease from the peak value) could be determined for ESR and WBC count on POD 7. Conclusion : Although slight differences were observed in numerical values and kinetics, sequential changes in inflammatory markers according to the duration of antibiotic administration showed similar patterns. Knowledge of CRP kinetics allows the assessment of the degree of difference between the clinical and expected values.