• Title/Summary/Keyword: Sigma S

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An Empirical Study on the Six Sigma's Effects on Quality Circles (6시그마가 품질분임조 활동에 끼친 영향에 대한 실증 연구)

  • 구일섭;김태성;임익성
    • Journal of Korean Society for Quality Management
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    • v.31 no.1
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    • pp.1-10
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    • 2003
  • In 1999, Six Sigma was introduced into Korea and after that it had general influence on company-wide management system. Quality Circles apply the various quality problem solving techniques such as QC 7 Tool, New QC 7 Tool, and statistical methods to rationalization, improvement in the shop floor. This paper empirically investigates the effects of Six Sigma on Quality Circles by analyzing the difference of problem solving technique's use. The number of teams employed in this study is 342, which participate in National Quality Circles Contest from 1997 to 2002 in Korea.

Killing Activity and Molecular Properties of Bacteriophage Sigma FA1 of Bacillus circulans (Bacteriophage Sigma FA1의 치사활성과 구조특성)

  • 김철호;김동수
    • Microbiology and Biotechnology Letters
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    • v.19 no.6
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    • pp.553-560
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    • 1991
  • In the previous paper (10). a new temperate phage, Sigma FA1 had been isolated from B. circulans. Sigma FA1 had an icosahedral head with a diameter of about 70 nm, and a tail about 15 nm long, and beared a circularly permuted, linear duplex DNA. Signla FA1 killed sensitive cells by a single-hit process. Phage DNA injected into the cell immediately after infection was degraded slowly. Our results indicate that the killing action of Sigma FA1 is different from the phenomenon of abortive infection and suggest that the killing might be caused by a proteinaceous component of Sigma FA1.

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Stabilization of the primary sigma factor of Staphylococcus aureus by core RNA polymerase

  • Mondal, Rajkrishna;Ganguly, Tridib;Chanda, Palas K.;Bandhu, Amitava;Jana, Biswanath;Sau, Keya;Lee, Chia-Y.;Sau, Subrata
    • BMB Reports
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    • v.43 no.3
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    • pp.176-181
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    • 2010
  • The primary sigma factor ($\sigma^{A}$) of Staphylococcus aureus, a potential drug target, was little investigated at the structural level. Using an N-terminal histidine-tagged $\sigma^{A}$ (His-$\sigma^{A}$), here we have demonstrated that it exits as a monomer in solution, possesses multiple domains, harbors primarily $\alpha$-helix and efficiently binds to a S. aureus promoter DNA in the presence of core RNA polymerase. While both N- and C-terminal ends of His-$\sigma^{A}$ are flexible in nature, two Trp residues in its DNA binding region are buried. Upon increasing the incubation temperature from 25$^{\circ}$ to 40$^{\circ}C$, $\sim$60% of the input His-$\sigma^{A}$ was cleaved by thermolysin. Aggregation of His-$\sigma^{A}$ was also initiated rapidly at 45$^{\circ}C$. From the equilibrium unfolding experiment, the Gibbs free energy of stabilization of His-$\sigma^{A}$ was estimated to be +0.70 kcal $mol^{-1}$. The data together suggest that primary sigma factor of S. aureus is an unstable protein. Core RNA polymerase however stabilized $\sigma^{A}$ appreciably.

APPLICATION OF CONVOLUTION SUM ∑k=1N-1σ1(k)σ1(2nN-2nk)

  • Kim, Daeyeoul;Kim, Aeran
    • Journal of applied mathematics & informatics
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    • v.31 no.1_2
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    • pp.45-54
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    • 2013
  • Let $$S^{\pm}_{(n,k)}\;:=\{(a,b,x,y){\in}\mathbb{N}^4:ax+by=n,x{\equiv}{\pm}y\;(mod\;k)\}$$. From the formula $\sum_{(a,b,x,y){\in}S^{\pm}_{(n,k)}}\;ab=4\sum_{^{m{\in}\mathbb{N}}_{m<n/k}}\;{\sigma}_1(m){\sigma}_1(n-km)+\frac{1}{6}{\sigma}_3(n)-\frac{1}{6}{\sigma}_1(n)-{\sigma}_3(\frac{n}{k})+n{\sigma}_1(\frac{n}{k})$, we find the Diophantine solutions for modulo $2^{m^{\prime}}$ and $3^{m^{\prime}}$, where $m^{\prime}{\in}\mathbb{N}$.

Anomalous Behavior of the Ethyl Group in the Aminolysis of S-Phenyl Acetate with Benzylamine in Acetonitrile

  • Lee, Ik-Choon;Lee, Hai-Whang;Lee, Byung-Choon;Choi, Jin-Heui
    • Bulletin of the Korean Chemical Society
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    • v.23 no.2
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    • pp.201-204
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    • 2002
  • The rates of the aminolysis of S-phenyl substituted-acetate series $(RC(=O)SC_6H_4Z$, with R=Me, Et, i-Pr, t-Bu and Bn) with benzylamines $(XC_6H_4CH_2NH_2)$ are not correlated simply with the Taft's polar $({\sigma}^{\ast})$ and/or steric effect constants $(E_s)$ of the substituents due to abnormally enhanced rate of the substrate with R=Et. Furthermore, the cross-interaction constant, ${\rho}x_z$ , is the largest with R=Et. These anomalous behaviors can only be explained by invoking the vicinal bond $({\sigma})$-antibond $({\sigma}^{\ast})$ charge transfer interaction between C-$C{\alpha}$ and C-S bonds. In the tetrahedral zwitterionic intermediate, $T^{\pm}$ , formed with R=Et the vicinal ${\sigma}_{c-c}-{\sigma}^{\ast}_{c-s}$ delocalization is the strongest with an optimum antiperiplanar arrangement and a narrow energy gap, ${\Delta}{\varepsilon}={\varepsilon}_{{\sigma}^{\ast}}-{\varepsilon}_{\sigma}$. Due to this charge transfer interaction, the stability of the intermediate increases (with the concomitant increase in the equilibrium constant K (= $k_a/k_{-a}$)) and also the leaving ability of the thiophenolate leaving group increases (and hence $k_b$ increases) so that the overall rate, $k_n\;=\;Kk_b$, is strongly enhanced. Theoretical support is provided by the natural bond orbital (NBO) analyses at the B3LYP/6-31+$G^{\ast}$ level. The anomaly exhibited by R=Et attests to the stepwise reaction mechanism in which the leaving group departure is rate limiting.

A Study on the Stress and Crystal in Die-Upsetted Nd-Fe-B-Cu Alloys as a Function of Working Temperature (가공온도에 따라 다이업셋한 Nd-Fe-B-Cu 합금의 응력과 결정에 관한 연구)

  • Park, J.D.;Yang, H.S.;Kwak, C.S.;Jeung, W.Y.
    • Journal of the Korean Society for Heat Treatment
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    • v.7 no.1
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    • pp.61-71
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    • 1994
  • This study is to investigate the stress distributions, crystal orientations and magnetic properties during die-upsetting according to working temperature of Nd-Fe-B-Cu alloys. The stress distributions in the specimens during compressing process were calculated by a finite element method program(SPID). The calculated stresses were effective stress (${\sigma}_{eff}$), compression stress(${\sigma}_z$), radial direction stress(${\sigma}_r$) rotational direction stress(${\sigma}_e$) and shear stress(${\tau}_{rz}$). The stress distributions of ${\sigma}_z$, obtained by a computer simulation showed that the stress components causing the magnetic alignment during die-upsetting of the cast magnets were very high at the center-part of a specimen, and decreased toward the periphery-part of a specimen. In view of the above results the magnetic properties should be better at the center-part of a specimen than any other parts. But the measured magnetic properties were better at the mid-part. These results should be due to the fact that the specimens were casted. Normally the magnetic properties are affected by the casting process as well as by the stress levels. ${\sigma}_r$, ${\sigma}_e$ are thought to affect the liquid phase flowing and domain patterns, respectively. The influence of ${\tau}_{rz}$ was trivial, ${\sigma}_{eff}$ distributed similar throughout the specimen. The Nd-rich phase appeared at the peripheral of the specimen where the stress level of ${\sigma}_r$, ${\sigma}_z$, was low or the stress level of ${\sigma}_e$ was high. The Nd-rich phase was squeezed out during die-upsetting. This phase had an effect on the crystal orientation and grain growth. The stress distributions of alloy were irregular at the parts of the specimen where the die contacted with specimen.

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An Application Study of Six Sigma in Clinical Chemistry (6 시그마의 적용에 대한 연구)

  • Chang, Sang Wu;Kim, Nam Yong;Choi, Ho Sung;Park, Yong Won;Chu, Kyung Bok;Yun, Kyeun Young
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.121-126
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    • 2004
  • The primary goal of six sigma is to improve patient satisfaction, and thereby profitability, by reducing and eliminating defects. Defects may be related to any aspect of customer satisfaction: high product quality, schedule adherence, cost minimization, process capability indices, defects per unit, and yield. Many six sigma metrics can be mathematically related to the others. Literally, six means six standard deviations from the mean or median value. As applied to quality metrics, the term indicates that failures are at least six standard deviations from the mean or norm. This would mean about 3.4 failures per million opportunities for failure. The objective of six sigma quality is to reduce process output variation so that on a long term basis, which is the customer's aggregate experience with our process over time, this will result in no more than 3.4 defect Parts Per Million(PPM) opportunities (or 3.4 Defects Per Million Opportunities. For a process with only one specification limit (upper or lower), this results in six process standard deviations between the mean of the process and the customer's specification limit (hence, 6 Sigma). The results of applicative six sigma experiment studied on 18 items TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA tests in clinical chemistry were follows. Assessment of process performance fits within six sigma tolerance limits were TP, ALB, T.B, ALP, AST, ALT, CL, CK, LD, K, Na, CRE, BUN, T.C, GLU, AML, CA with 72.2%, items that fit within five sigma limits were total bilirubin, chloride and sodium were 3 sigma. We were sure that the goal of six sigma would reduce test variation in the process.

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Framework and Tool for Quantitative Six Sigma Project Management (정량적 식스 시그마 프로젝트 관리를 위한 프레임워크와 도구)

  • Park, Hyun-Cheol;Ryu, Ho-Yeon;Baik, Jong-Moon
    • Journal of KIISE:Software and Applications
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    • v.35 no.4
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    • pp.234-244
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    • 2008
  • Since the advent of Six Sigma in 1980's, Six Sigma is widely used in various industry areas, such as manufacturing, financial, government, and service, and proves its innovation ability and value by providing lots of success stories. Several researches have been conducted to adopt Six Sigma for Software Development and Software Quality Assurance-Software Six Sigma. Although the wide use of Six Sigma, there is no software tool to support the execution of Six Sigma Project. For this reason, the Quantitative Six Sigma Project Management is required to support for measuring and analyzing Six Sigma Projects, storing and reporting the results from Six Sigma Projects, and managing Six Sigma Projects through the whole process of, DMAIC or DMADV. In this paper, we introduce the design and implementation of a Quantitative Six Sigma Project Management Framework and Tool. The execution of Six Sigma Project based on Six Sigma Project Management Tool benefits the quantification, the systematization, and the integration.

Effects of an Anisotropic Consolidation on the Undrained Shear Strength of a Normally Consolidated Clay (정규압밀점토의 비배수 전단강도에 대한 이방압밀효과)

  • 강병희;윤호창
    • Geotechnical Engineering
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    • v.10 no.1
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    • pp.63-70
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    • 1994
  • In-situ soil is anisotropically consolidated at rest, and the coefficient of earth pressure at rest $K_0$ is dependent on the properties of soil and stress history. In order to estimate roughly the in-situ undrained shear strength of a $K_0$-anisotropically normally consolidated clay from isotropic consolidated undrained test, consolidated undrained shear testy with four different consolidation pressure ratios ($K={\sigma}'_{3c}/{\sigma}'_{1c}$) were performed and test results showed K-$\alpha$ relationship, representing the strength ratio $\alpha$ as ($S_u/{\sigma}'_{1c})_{CKU}=\alpha(S_u/{\sigma}'_{1c})_{CIU}$. Strength ratio u increases with increasing consolidation pressure ratio. And the angle of internal friction $\Phi'$and angle ratio $\Phi'_{CKU}/\Phi'_{CIU}/$ are increased with the increament of K-value.

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A study the success of six sigma in the service industry (서비스 기업에서의 6시그마 성공요인에 관한 연구)

  • Kim, Soo-Youn;Ree, Sang-Bok
    • Proceedings of the Korean Society for Quality Management Conference
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    • 2006.04a
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    • pp.450-455
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    • 2006
  • The methodology of six sigma originated at Motorola in the early 1980s is now days proved to be an effective way in improving the quality. Many companies are paying their attentions to 6 sigma quality technique, proved to be successful by many examples of advanced firms. However most companies where Six sigma is implemented confront many difficulties in service industry. In paper we research successful Six Sigma in the service industry.

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