Objective:The purpose of this study is to suggest the methodology for establishment of safety culture in industry. Background: There have been studies indicating positive relation between safety culture and safety performance. But the areas of those efforts have been mainly focused on elements or factors consisting of safety culture. So it is expected that studies on methodologies for developing process of the culture could contribute for the industry to understand and apply it accordingly in order to improve their practices. Method: In this study, the scope was considered just for industry, even though there are many fields of culture. As the first step, the limitations of regulatory control and efforts by industry were reviewed, and the trends of researches were presented. In the second step, the global company practices were provided with detailed activities. Results: This paper showed the limitations of present state in government strategies and industry for safety culture improvement. Also the restricted areas in researches were shown. As one of the solutions to resolve those things, such global company practices as perception to safety journey, the steps of culture development, total safety philosophy, structure and elements of safety process, standards and procedures, training, and up to keys to success were suggested. Conclusion: Through this study, the development of the structure of safety process which consists of many purposeful activities has been derived to be very important. Because it will be the seeds of safety culture expressing their thinking process and behaviors. Also it is required to approach success step by step according to the achievement of each step. Application: This study can be used to develop the methodology and safety process in industry with different viewpoints for safety culture establishment.