A pilot-scale experiment for the treatment of red tide in the enclosure was done in sea area of Shandong Province, P. R. China on Aug. 25, 2002. With the method of strong dielectric barrier discharge in microgap, $O_2$in air and $H_2O$ in seawater are ionized and dissociated into large numbers of OHㆍradicals, and then dissolved into a part of seawater to form OHㆍsolution of high concentration. With OH' concentration of 0.68mg/L, the kill efficiencies of 29 kinds of red tide organisms such as Chaetoceros lorenzianus and so on reached 99.89%, in which the kill efficiencies of bacterium and vibrio were 100%, and that of Gonyaulax cysts and Prei. Cysts were up to 100%. At the same time, the content of chlorophyll-a was decreased into the lowest limit of test. DO saturation of seawater was greatly increased to 100% because the residual OHㆍradical was decomposed into $H_2O$ and $O_2$after 20 minutes, Therefore the treatment of red tide using OHㆍradicals is a kind of advanced oxidation technology, which realizes zero pollution, zero emission and zero residual in the process of the production of OHㆍradicals and the treatment of red tide.