Recently, the R&D of weapon systems has been strengthened in terms of economic cost management throughout the entire life cycle from performance. This study proposes the method for setting the optimal maintenance concept based on RAM-C in weapon system acquisition stage by calculating the operation & maintenance cost as well as reliability, availability, and maintainability. First, we design a simulation model for analysis of weapon system logistic supportability. In addition, information such as weapon system Part Breakdown Structure, operation & maintenance system, cost, and etc for simulation analysis, is applied. Based on the obtained simulation results, the optimal plan is selected among alternatives designed with various maintenance concepts through normalization and weight setting. It is expected to be of technical help in the application of RAM-C in the weapon system acquisition stage.