Purpose: The purpose of study was to assess the health promoting lifestyle among hospital nurses and to investigate the relationships between the health promoting lifestyle, resourcefulness, and perceived health status. Methods: The subjects were 400 nurses working at three university hospitals. The data were collected by self-administered questionnaires from September 1st to September 30th, 2008. Results: The range of Health Promoting Lifestyle Profile (HPLP) was 71-185, the average score was 112.50, and the item mean was 2.16 (total 4). The range of resourcefulness was 9-50, and the average score was 16.56. The range of perceived health status was 4-13, and the averae score was 9.52. Health promoting lifestyle was showed significantly positive correlations with resourcefulness (r=.473, p<.001), and with perceived health status (r=.176, p<.001). The independent variables including resourcefulness, religion, working shift, sleeping hours, and exercise explained 58.6% of the variance of health promoting lifestyle. Especially, resourcefulness explained 53.2% of the variance of health promoting lifestyle. Conclusion: Resourcefulness was identified as the most important variable contributing to the performance of health promoting lifestyle.