• Journal of Pharmaceutical Investigation
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• v.40 no.6
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• pp.379-386
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• 2010

Mono PEGylated rhG-CSF (PEG-G-CSF) prepared by utilizing unique PEG was purified and characterized by cation-exchange chromatography. A unique, trimer-structured PEG was chosen for PEGylation of rhG-CSF among various PEG moieties. The in-vitro bioactivity, stability, and pharmacokinetics of mono-PEG-G-CSF were examined and compared to those of native rhG-CSF. Mono PEG-G-CSF exhibited reduced in-vitro bioactivity to native rhG-CSF but showed an excellent in-vivo bioactivity and stability. Furthermore, it showed markedly reduced clearance in rats, thereby increasing the biological half-life by about 4.5-fold compared to that of native rhG-CSF. The results suggest that this unique, trimer-structured 23 kDa PEG can provide advantages to improve the bioactivity of therapeutic proteins in clinical use.

• Journal of Institute of Control, Robotics and Systems
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• v.19 no.12
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• pp.1089-1093
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• 2013

Depth extraction using the structured illumination method is popularly applied since it has the benefit of measuring the object without contact. With multiple spatial frequencies and phase-shifting techniques, it is possible to extract the depth of objects with large discontinuity. For applications such as 3D (Three Dimensional) displays, 3D information of the object is required and is useful if corresponding to each view of the display. For this purpose, hypercentric optics is appropriate to measure the depth information of an object with a large field of view that is applicable for a 3D display. By experiment, we present the feasibility for phase-shifting profilometry using hypercentric optics to obtain the depth information of an object with the field of view appropriate for a 3D display.

• The Journal of the Korea institute of electronic communication sciences
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• v.5 no.5
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• pp.459-464
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• 2010

Computer programs are required from all areas in society including machine, space, aviation, and medicine. However, the programming curriculum is getting hard despite a lot of teaching materials and video lessons. Programming languages are very diverse, but most of them use the same structure, and they only have different expression methods. Therefore, if one learns one programming language, then it doesn't need to spend a lot of time and efforts to learn another programming langue. Most programming languages use the structure of sequence, selection, and repletion in general. The important thing for programming learners is the structure or algorithm of programming not the grammar of program. This study designed and implemented the language learning system to learn structured programming by using a flowchart.

• Journal of the Ergonomics Society of Korea
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• v.26 no.2
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• pp.61-66
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• 2007

The networked home is connected to the external world using a high speed network. The devices inside the house are connected using a wired and wireless network. Acquiring the user data is an essential step for designing the user interface in user centered design. In networked home, the numbers of use cases are exponentially increased because connected use cases are considered. Because the user data for networked home are too complicated, they are acquired and analyzed by a structured methodology. We surveyed 40 people to acquire the context data home and analyzed by 5W1H (Who, Where, What, When, Why, How). We established a framework for the user data using tasks, user, time, space, objects and environment. The data for home context was structured by our framework. This framework makes simple the home context and is helpful for user interface design in home network.

• Journal of East-West Nursing Research
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• v.20 no.1
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• pp.1-8
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• 2014

Purpose: The purpose of this study was to investigate the effectiveness of the coping and self-care behaviors between the individual and group education using the structured programs for the patients in chemotherapy. Methods: The quasi experimental study was designed for this study, and 30 patients received individual education and 30 patients received group education. Collecting data had been done through the seven months from March to Oct. 2011. Results: Hypothesis 1: "There could be differences in aspects of coping between the two groups educated using a structured education program" was rejected (F=2.71, p=.105). Hypothesis 2: "The individually educated group using the structured education program will have higher scores than the group education in self-care behaviors" was supported because there were statistically significant differences (F=4.16, p=.046). Conclusion: It was confirmed that individual education programs, among the patient education for cancer patients can be adopted as nursing intervention in nursing practice to improve self-care behaviors. However, there were no differences between th two group in the aspects of coping.

• Journal of the Korea Society of Computer and Information
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• v.10 no.3 s.35
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• pp.331-337
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• 2005

'Supplement 23:DICOM SR' announced on April 2000 made possible co-relations between the clinical reports and human body parts by standardizing the exchange of clinical information. DICOM SR uses its own coding schemes and values to represent information, which convey hierarchically structured content items. This paper analyzes radiology reports produced in HIS(Hospital Information System) and categorizes content structures into three parts such as, finding, conclusion, and recommendation, and implements a system which can be used by clinicians. Digital X-ray images and their reports have been managed separately. Since the report made by DICOM SR can refer to images, the integrated information of reports and images is possible.

• Korean Journal of Food Science and Technology
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• v.37 no.5
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• pp.709-712
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• 2005

Structured lipid (SL) was synthesized by enzymatic interesterification of algae oil and corn oil in stirred tank batch reactor, The reaction, performed for 15hr at $65^{\circ}C$, was catalyzed by sn-1,3-specific lipase RM IM from Rhizonucor miehei without organic solvent. DHA, oleic acid, and linoleic acid contents of SL were 14.9, 17.3, and 31.8 mol%, respectively. ${\alpha}-,\;{\gamma}-,\;and\;{\delta}-tocopherol$ contents and physiochemical property of SL were evaluated. During 15 hr reaction, most reaction occurred within 6 hr, and highest relative production rate was observed between 3 to 6 hr.

• Journal of the Korean housing association
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• v.15 no.3
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• pp.83-91
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• 2004

In a planning stage, the assessment system is required to select the proper alternative, reflected the environmental affects such as energy, $CO_2$ and $SO_x$. Unit of energy consumption, $CO_2$ emission and $SO_x$ emission among various assessment systems could be effectively utilized to select the better alternative among various building types. But researches for these areas has not been conducted systematically, but limitedly and sporadically. In this paper, it aimed at providing the unit of energy consumption, $CO_2$ emission and $SO_x$ emission to evaluate the environmental affects between the steel-structured apartment building and wall-typed apartment building. For this, the input-output analysis could be utilized in the construction stage with two-type apartment housing. This approach can be utilized to compare the various alternatives in aspect of the energy consumption and the environment affect, and to select the relatively better alternative. This study found that the unit of energy, $CO_2$ and $SO_x$ of the steel-structured apartment building is lower than that of the wall-typed building

• Journal of Sensor Science and Technology
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• v.14 no.2
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• pp.116-124
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• 2005

In this paper range measurement systems are designed using an ultrasonic sensor and a camera. An ultrasonic sensor provides the range measurement to a target quickly and simply but its low resolution is a disadvantage. We tackle this problem by employing a camera. Instead using a stereoscopic sensor, which is widely used for 3D sensing but requires a computationally intensive stereo matching, the range is measured by focusing and structured lighting. In focusing a straightforward focusing measure named as MMDH(min-max difference in histogram) is proposed and compared with existing techniques. In the method of structure lighting, light stripes projected by a beam projector are used. Compared to those using a laser beam projector, the designed system can be constructed easily in a low-budget. The system equation is derived by analysing the sensor geometry. A sensing scenario using the systems designed is in two steps. First, when better accuracy is required, measurements by ultrasonic sensing and focusing of a camera are fused by MLE(maximum likelihood estimation). Second, when the target is in a range of particular interest, a range map of the target scene is obtained by using structured lighting technique. The systems designed showed measurement accuracy up to 0.3[mm] approximately in experiments.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.665-666
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• 2006

Undoped $CoSb_3$ powders were synthesized by mechanical alloying (MA) of elemental powders using a nominal stoichiometric composition. Nano-structured, single-phase skutterudite $CoSb_3$ was successfully produced by vacuum hot pressing (VHP) using MA powders without subsequent annealing. Phase transformations during synthesis were investigated using XRD, and microstructure was observed using SEM and TEM. Thermoelectric properties in terms of Seebeck coefficient, electrical conductivity, thermal conductivity and figure of merit(ZT) were systematically measured and compared with the results of analogous studies. Lattice thermal conductivity was reduced owing to increasing phone scattering in nano-structured MA $CoSb_3$, leading to enhancement in the thermoelectric figure of merit. MA associated with VHP technique offers an alternative potential processing route for the process of skutterudite.