• The Korean Journal of Cytopathology
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• v.4 no.2
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• pp.176-180
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• 1993

Clonorchiasis is common in Korea. The coinfection of amebic abscess with clonorchiasis is not rare in endemic areas. The coinfection may influence on its manifestations each other. We experienced a human case with unusal manifestation of amebic liver abscess associated with coinfection by Clonorchisis sinensis. The case was an 80-year-old female. She lived in Yongil-gun, Kyongsangbuk-do, Korea, She had multiple amebic abscess cavities in the liver, one of which subsided spontaneously and others newly appeared. She was diagnosed by CT guided aspiration of the cyst, which revealed trophozoites of ameba and eggs of C. sinensis. She was treated with praziquantel and metronidazale and was cured.

• Parasites, Hosts and Diseases
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• v.51 no.3
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• pp.383-385
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• 2013

Uzbekistan is endemic of cystic echinococcosis (CE). In order to estimate endemicity of CE, we collected data from emergency surgery due to CE in 2002-2010 and also investigated the prevalence of hydatid cysts in the liver and lungs of sheep at an abattoir in Uzbekistan from July 2009 to June 2010. In 14 emergency hospitals, 8,014 patients received surgical removal or drainage of CE during 2002-2010, and 2,966 patients were found in 2010. A total of 22,959 sheep were grossly examined of their liver and lungs, and 479 (2.1%) and 340 (1.5%) of them were positive for the cyst in the liver and lungs, respectively. Echinococcus granulosus is actively transmitted both to humans and sheep, and CE is a zoonotic disease of public health priority in Uzbekistan.

• Journal of fish pathology
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• v.2 no.2
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• pp.71-74
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• 1989

Ichthyophonus disease had broken out among rock bream in Dec. 1989. Diseased-fish showed markedly stunted growth and darkish coloration, and anatomically the liver with small white nodules, tumefied spleen with its granulous surface, and the markedly tumefied kidney. Microscopic examination of liver, kidney, spleen and gill from 10 rock bream revealed cyst of the fungus Ichthyophonus sp. Rock bream were heavily infected with the highest concentrations of spherical multinucleate bodies in the liver, the spleen, the kidney and the gills. In heavily infected sectors of tissue a common necrotic zone was formed around spore aggregates. Spherical multinucleate hyphal terminal bodies developed thin hyphae longer than 1mm which divided into many branches.

• Journal of Aquaculture
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• v.7 no.4
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• pp.225-237
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• 1994

Survival and growth rates of flounder larvae fed rotifers and Artemia nauplii enriched by various bio-enrichment techniques were investigated. Enriched materials used in the study were $12\omega-yeast$, 2 commercial emulsified oil and microparticulated products. $\omega-yeast$ were added with one kinds of oils (cuttlefish liver oil, sardine oil, Alaska pollock liver oil, linseed oil) at the level of $5\%,\;15\%\;and\;25\%$. The results are as follows: 1. The growth rate of rotifers cultured with $\omega-yeast$ added $15\%$ cuttlefish liver oil was the best among 12 kinds of $\omega-yeast$ and this performance was almost the same with that of rotifers fed on Chlorella. 2. Survival and growth rates of flounder larvae fed on rotifers and Artemia nauplii enriched with $\omega-yeast$ and the other commercial products were higher than that those of larvae cultured with only Chlorella and non-enriched Artemia. The optimum contents of the cuttlefish liver oil in $\omega-yeast$ for rotifers and Artemia enrichment were $15\%\;and\;25\%$, respectively. 3. Optimum enrichment time and supply amount of $\omega-yeast$ for Artemia nauplii were 6 hr., 1.5 g/g cyst, respectively.

• Korean Journal of Veterinary Research
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• v.15 no.1
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• pp.27-38
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• 1975

The following tumors occurring naturally in the dog were studied pathologically and discussed briefly. Tumors of the skin and subcutis: Fibroma, Lipoma, Epidermal cyst, Melanosarcoma, Sweat gland adenoma, Mastocytoma (2 cases), Mastosarcoma, and Sebaceous gland carcinoma. Tumors of the spleen and lymph node: Fibrosarcoma of the capsule of spleen, Leiomysarcoma of the spleen, and Lymphosarcoma of the lymph node (2 cases). Tumors of the lung: Bronchogenic carcinoma (3 cases), Adenocarcinoma type, Squamous carcinoma type, and Undifferentiated (round cell) carcinoma type respectively. Tumors of the alimentary tract and liver: Fibroma of the stomach, Hemangioma of the liver, Bile duct carcinoma, Liver cell carcinoma, and Myelogenous leukemia manifested in the liver. Tumor of the peritoneum: Fibrosarcoma. Tumors of the urogenital system: Fibroma of the uterus, Fibroma of the prepuce, Follicular cyst of the ovary, Transmissible venereal tumor of the vagina (6 cases), Carcinoma of the kidney, Adenoma of the prostate (2 cases), and Seminoma of the testis. Tumors of the mammary gland: Mixed tumor (2 cases), and Myoepithelioma. Tumor of the nervous system: Neurofibrosarcoma of the thigh.

• BMB Reports
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• v.37 no.5
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• pp.612-617
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• 2004

Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder characterized by the formation of fluid-filled cysts in the kidney and progressive renal failure. Other manifestations of ADPKD include the formation of cysts in other organs (liver, pancreas, and spleen), hypertension, cardiac defects, and cerebral aneurysms. The loss of function of the polycystin -1 and -2 results in the formation of epithelium-lined cysts, a process that depends on initial epithelial proliferation. cDNA microarrays powerfully monitor gene expression and have led to the discoveries of pathways regulating complex biological processes. We undertook to profile the gene expression patterns of epithelial cells derived from the cysts of ADPKD patients using the cDNA microarray technique. Candidate genes that were differently expressed in cyst tissues were identified. 19 genes were up-regulated, and 6 down-regulated. Semi-quantitative RT-PCR results were consistent with the microarray findings. To distinguish between normal and epithelial cells, we used the hierarchical method. The results obtained may provide a molecular basis for understanding the biological meaning of cytogenesis.

• Tuberculosis and Respiratory Diseases
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• v.70 no.4
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• pp.338-341
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• 2011

Hydatid disease is caused by the larval stage of taenia $Echinococcus$, which endemic in the Mediterranean region. Recently, the prevalence of the disease has increased worldwide due to an increase in the frequency of travel and immigration. As the infested larvae migrate through the bloodstream, the final destination is most commonly the liver or lungs; direct pleural invasion is very rare. A 50-year-old diabetic Korean man presented with an incidentally noted 2 cm right pleural nodule. On follow up imaging after three months, its size had increased. To confirm the diagnosis of the lesion, surgical excision was performed. Histopathological examination showed the diagnosis of a hydatid cyst. The patient had no history of overseas travel, but lives in an urban area where many foreign workers from endemic countries reside. This is the first reported case of primary pleural hydatid disease in a non-endemic country.

• Parasites, Hosts and Diseases
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• v.50 no.1
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• pp.53-56
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• 2012

Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of $Satureja$ $khuzestanica$ leaves and aqueous extracts of $Olea$ $europaea$ leaves on hydatid cyst protoscolices. $Echinococcus$ $granulosus$ protoscolices were collected from the liver of sheep infected with the hydatid cyst. Various concentrations of plant extracts were used in different exposure times for viability assay of protoscolices. Among the olive leaf extracts tested, 0.1% and 0.01% concentrations had strong scolicidal effects in 120 min. $S.$ $khuzestanica$ 0.1% had very strong scolicidal effects in 30, 60, and 120 min of exposure times and the mortality rate decreased with the lower concentration. The finding have shown that the scolicidal activity of $S.$ $khuzestanica$ against cystic echinococosis protoscolices were more effective, while the $O.$ $europaea$ extract showed less effects.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.4 no.1
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• pp.113-119
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• 2001

Mesenchymal hamartoma is an uncommon benign tumor usually found in childhood, especially during the first two years of life. The tumor consists of a solid component and multiple cyst. Without treatment, these lesions can grow to an enormous size. We experienced a case of mesenchymal hamartoma which was found incidentally, in a 8 month old girl who had ascending cholangitis after Kasai operation due to biliary atresia. On abdominal ultrasonography and CT, there was a well-defined homogeneous small echogenic mass in the right lobe of the liver with cirrhosis. Five months later, she underwent liver transplantation. Gross picture of the resected liver showed a dark greenish pigmented solid mass in the right lobe of the cirrhotic liver. Microscopic findings showed reactive mesenchyma and epithelial overgrowth.

• Journal of Veterinary Clinics
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• v.22 no.4
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• pp.401-403
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• 2005

A seven-year old female captive Japanese macaque (Macaca fuscata) was mobbed by its cage mates and subsequently died due to trauma. An incidental finding of multiple biliary cystadenoma in the liver is herein reported. Grossly, multiple small cysts were observed throughout the surface of the liver. One particular cyst that measured $1.3\times1.2\times1.0cm$ and contained mucinous fluid was observed in the center of the liver. Microscopically the cysts were lined by biliary epithelium that varied from simple cuboidal to columnar cells. Signs of malignancy and metastasis to other organs were not observed. This is the first report of biliary cystadenoma in Japanese macaque.