• 대한한의학원전학회지
• /
• 제19권4호
• /
• pp.219-225
• /
• 2006

The result is the followings after investigating composition, dosage and usage of Sagunjatang(四君子湯), Samultang(四物湯), Palmultang(八物湯), Sipjeondaebotang(十全大補湯) in literature by country and Era 1. Sagunjatang has become equal to Panax ginseng(人蔘), Atractylodes japonica(白朮), Poria cocos(복령) each for 2 Jeon(錢), Glycyrrhiza uralensis(甘草) 1 jeon since the Ming Dynasty in China and it is standardized by Panax ginseng, Atractylodes japonica, Poria cocos and Glycyrrhiza uralensis each for 1 Jeon 2 Pun(分) 5 Ri(里) since Dongeuibogam in Korea. 2. Samultang has become equal to Angelica gigas(當歸) and Rehmannia glutinosa(地黃) each three Jeon, Cnidium officinale(川芎) is 1 Jeon 2 Pun or 1 jeon and Paeonia lactiflora(芎藥) 2 Jeon since the Ming Dynasty in China and it is standardized by Angelica gigas, Cnidium officinale, Paeonia lactiflora and Rehmannia glutinosa each for 1 Jeon 2 Pun 5 Ri since Dongeuibogam in Korea. 3. In the case of Palmultang, compositional usage of medicine was different in the Ming Dynastry and the Ching(靑) Dynastry in China. Total dosage was increased and ratio of Angelica gigas and Rehmannia glutinosa was increased comparatively in the Ching Dynasty. All prescription of medicine was consisted of 1 Jeon 2 Pun and specific dosage was presented except Euirimchwalyo(醫林撮要) that dosage was not recorded in Korea. 4. Sipjeondaebotang tended to increase total dosage in the latter part in China. Dosage was mostly used 1 Jeon thus Dongeuibogam but Bangyakhap(方藥合編) used 1 Jeon 5 Pun differentially.

• 대한한의학방제학회지
• /
• 제23권1호
• /
• pp.25-53
• /
• 2015

This report describes 90 prescriptions related to the use of Ostericum Radix(OR) blended as the main ingredient in the Dongeuibogam.

The following conclusions were reached through investigations on the prescriptions that use OR as a key component.

Prescriptions where OR was used as one of the monarch(drug) utilized for 27 therapeutic purposes in total.

It was searched that the frequency of prescriptions in the therapeutic purposes were as follows. The chapter of eyes is 22.2%, the wind is 13.4%, the child 11.1%, the cold is 8.9%, the head is 6.7%, the malaria disease 4.5% in the order.

Prescriptions that utilized OR as the main ingredient were most used for treating diplopia, facial nerve palsy, headache and a fever in the whole body. These were also used for treating 55 different types of diseases.

The dosage of OR in formulas was ranging from 2pun(about 0.75g) to 2don(about 7.5g). However, 1don(about 3.75g) was most used for clinical application.

We can find out that according to herbs or prescriptions blended with itself, OR made a variety of functions to eliminate cold with wind, humidity, pain, and convulsions from the body. And also, Bangpungtang was the most useful base prescription which used OR as the main component.

• 대한한의학방제학회지
• /
• 제25권3호
• /
• pp.413-427
• /
• 2017

Objectives : This report describes 75 studies related to the use of Zingiberis siccatum Rhizoma mainly blended from Dongeuibogam. Methods : The 75 Prescriptions of Consumptive part in DonguiBogam analysed frequency of basic prescriptions, symptoms of prescriptions and the pathology. Results : Prescriptions that Zingiberis siccatum Rhizoma was taken as a monarch drug are utilized for 25 therapeutic purposes, for example, cold disease, stool disease, cough disease. In particular, 16.0% of prescriptions appear in the chapter of cold. Prescriptions that utilize Zingiberis siccatum Rhizoma as the main component are used in the treatment of cold, stool and cough disease. Zingiberis siccatum Rhizoma is used in pathogenic factors such as weakness cold and cold strength and used in pathology related to the spleen and stomach system. The dosage of Zingiberis siccatum Rhizoma is 5pun(about 1.88g) to 4nyang(about 150.4g), however 1don(about 3.75g) has been taken the most for clinical application. Ijungtang is the most useful base prescriptions which use the Zingiberis siccatum Rhizoma as the main ingredient. Conclusions : As a result of Study on Analysis all Prescriptions of Zingiberis siccatum Rhizoma in DonguiBogam. We can understand more about basic prescriptions, symptoms of prescriptions and the pathology that are using for Zingiberis siccatum Rhizoma.

• 대한한의학방제학회지
• /
• 제28권4호
• /
• pp.365-384
• /
• 2020

Objectives : This report describes 241 prescriptions related to the use of Gardenia Fructus blended prescriptions from Dongeuibogam. Methods : The following conclusions were reached through investigations on the prescriptions that use Gardeniae Fructus. Results : The Gardeniae Fructus is used in 49 fields of treatment such as urinary diseases, jaundice and furuncle, etc. Prescriptions that utilize Gardeniae Fructus are used in the treatment of fever, eye disease, hemorrhage, skin disease, ear disease, internal disease and so on. In the view of the causative agent of a disease, the prescriptions which are compounded with Gardeniae Fructus are related to endogenous agents such as jaundice, seven emotion, alcohol, exogenous agents such as cold, wind, heat and non-endo-exopathogenic factors like disease due to external factor, injury. The dosage of Gardeniae Fructus is 1pun(about 0.375) to 5don 5pun(about 21g), however 5pun(about 1.87g)~1don(about 3.75g) has been taken the most for clinical application. Conclusions : Hwangryunhaedok-tang is the most base prescriptions which use the Gardenia Fructus. Gardeniae Fructus is mainly used as a raw material.

• 대한한의학원전학회지
• /
• 제23권6호
• /
• pp.27-44
• /
• 2010

In order to setup the diet guideline of five grains, five meats, five fruits, and five vegetables for the diseases of five organs, I reviewed the their tastes by comparing "Naekyeong" with "Euhakibmun", "Dongeuibogam". 'Ma(麻)' in "Naekyeong" means not a hemp, a ramie or a jute, but a sesame(胡麻;참깨). 'Maik(麥)' in it means both a barley(大麥;보리) and a wheat(小麥;밀). 'Guak(藿)' in it means bean leaves(콩잎), leaves of a red-bean(팥잎) or brown seaweed(海藻;미역). 'Gyu(葵)' in "Euhakibmun Jangbujobun(臟腑條分)" is a miswritten word for 'Welsh onion' caused by similarity of shape of word. Food of a salty taste according to five elemental arrangement in "Naekyeong" is really salty according to "Euhakibmun" and "Dongeuibogam". But a barley(大麥) and a wheat(小麥) of sour taste are bitter, a chicken of sour taste or hot taste is sweet, nonglutinous millet of sour taste is sweet, an apricot of bitter taste is hot, a sesame seed of sweet taste is sour, a nonglutinous rice of hot taste is sweet, and a horsemeat of hot taste is bitter according to them. There are two ways to recommend the food for diseases of five organs. One way is to promote or control the Qi(氣) of five organs according to "Somun(素問)" and "Euhakibmun Jangbujobun", the other way is to build up the Yin(陰血) of five organs according to "Yungchu(靈樞) five tastes(五味)". The two different ways are not contradictory to each other, but complement on the view point of their substances(體) or actions(用).

• 대한한의학방제학회지
• /
• 제26권2호
• /
• pp.129-145
• /
• 2018

Objectives : This report describes 70prescriptions related to the use of Radix Aconiti Lateralis Preparata mainly blended from Dongeuibogam. Methods : The following conclusions were drawn through investigations on the pre-scriptions that use Radix Aconiti Lateralis Preparata as a key component. Results : Prescriptions that Radix Aconiti Lateralis Preparata was taken as a monarch drug are utilized for 31 therapeutic purposes, for example, cold disease, stool disease, child disease. In particular, 17.3% of prescriptions appear in the chapter of cold. Prescriptions that utilize Radix Aconiti Lateralis Preparata as the main component are used in the treatment of cold, diarrhea and child disease, Bi syndrome due to pathogenic wind, cold and damp and they are also used for treating 55 different types of disease. Radix Aconiti Lateralis Preparata is used in pathogenic factors such as wind, cold and dampness and used in pathology related to the kidney and spleen and stomach system. The dosage of Radix Aconiti Lateralis Preparata is 2pun(about 0.75g) to 5don(about 18.8g), however 1don(about 3.75g)~1don 5pun(about 5.63g) has been taken the most for clinical application. Conclusions : Gangbutang and Ijungtang are the most useful base prescriptions which use the Radix Aconiti Lateralis Preparata as the main ingredient.

• 대한한의학방제학회지
• /
• 제19권1호
• /
• pp.79-90
• /
• 2011

Objectives : This study was performed to analysis the composition of herbal formulations about a series of Wolgug-Hwan(WGH, formed by Gukchur-won and Sagung-san) in Dongeuibogam written by Heo Jun. Methods : The series of WGH in Dongeuibogam were selected by 'Prescription Lineage Graph' (http://164.125.206.43/PrescriptionLineageGraph.aspx) established by prof. Lee at Pusan National University. In the analysis of a series of WGH, we used some formulation books including classics. Results : Gaeuldogi-tang(GDT) is formed by WGH, Yeonggangchulgam-tang(YGT), Yugil-san (YIS) and Gungchul-san. Cheongul-san(CUS) is formed by WGH, Ijin-tang(IJT), YGT and Haegeum -hwan(HGH). Sosikcheongul-san(SCS) is formed by CUS and IJT. Jeungmiijin-tang(JIT) is formed by WGH, IJT, Sambaek-tang and Gyullyeonjichul-hwan. Sihoeokgan-tang(SET) is formed by WGH, Sihosogan-san(SSS) and Jigolpi-eum. Wolgukbohwa-hwan(WBH) is formed by WGH, Bohwa-hwan, Mokyangjichul-hwan and Hwangnyeon-tang(HNT). Chimsa-hwan(CSH) is formed by WGH, Injinho-tang(IHT), Yungmisamneung-hwan, Jeungmisamul-tang and Sinseongugi-tang. Conclusions : SCS, CUS, or JIT has been used frequently in case of phlegm-fire. These are formulated by the combination of WGH and IJT with Samseon-san or HGH or Jichul-hwan according to the special symptoms, respectively. SET which is formulated by WGH and SSS has been used in case of stagnation of liver-qi. GDT, WBH or CSH has been used in damp-heat. These are formulated by the combination of WGH with YIS, HNT, or IHT, respectively.

• 한국의사학회지
• /
• 제21권2호
• /
• pp.13-28
• /
• 2008

Medical Science in general is a study dedicated to human. It is important to understand how human is being seen in medical science. The difference of this perspective among various medical science in different parts of the world shows the difference in ways of understanding human, and furthermore, difference in ways of understanding diseases. On the other side, Oriental Medicines tends to perceive human as a whole. Heo Joon's perspective on human is elaborated in his book, Dongeuibogam. The foundation of this perspective is found is the Thesis of Four Generals and Five Constants, Neijing. There are many discussions in the Thesis of Four Generals and Five Constants, which include the thesis of correspondence between nature and human: which define the relationship between human and nature in terms of four generals and five constants, and the thesis of xing and color: which offers the tool of making diagnosis on Four Generals and Five Constants, since xing and color designates the result of Four Generals and Five Constants. Other methods are also merely ways of expressing Four Generals and Five Constants in different angle. After all, the perspective of human shown by Heo Joon can be explained in one word as the thesis of Four Generals and Five Constants, and the principles of its theory, which are the thesis of correspondence between nature and human and the thesis of xing and color are also nothing more than a tool of underatanding Four Generals and Five Constants more efficiently.

• 대한한의학방제학회지
• /
• 제26권3호
• /
• pp.223-236
• /
• 2018

Objectives : We compared the inhibitory effects of herb-combined remedies, which were recorded on "Yooam" prescription of Dongeuibogam, on cell migration and invasion, two critical cellular processes that are often deregulated during metastasis, in B16F10 melanoma cells. For this purpose, water extracts of Sipyukmiryukieum (SYMRKU), Danjacheongpitang (DJCPT), Cheongganhaeultang (CGHUT) and Jipaesan (JPS) were used. Methods : Cytotoxicity was assessed by an MTT assay. Wound healing and matrigel transwell assays were used to examine on B16F10 cell migration and invasion. The levels of mRNA and protein expression of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) were analyzed by RT-PCR and Western blotting. Results : Our data showed that DJCPT showed the strongest inhibitory effect among the four prescriptions in inhibiting cell motility of B16F10 melanoma cells within the concentration range that was not cytotoxic. The inhibitory potential of colony formation was higher in DJCPT and SYMRKU compared to the other two types of prescriptions, and the inhibitory effect of invasiveness is shown in order of DJCPT, SYMRKU, CGHUT and JPS. DJCPT, and SYMRKU strongly inhibited the activity and expression of MMP-2 and MMP-9, which are important mediators in cancer invasion, compared to CGHUT and JPS, and the increased expression of TIMP-1 and TIMP-2 was also more effective in these two prescriptions. In conclusion, DJCPT is expected to exhibit the most potent blocking effect on migration and invasion among four herb-combined remedies compared in B16F10 melanoma cells. Conclusion : Overall, the results of this study will be used as an important source to validate these prescriptions in animal models and to understand the mechanism of action of herbal remedies recorded in Dongeuibogam.

• 대한한의학방제학회지
• /
• 제22권1호
• /
• pp.13-32
• /
• 2014

Objectives : Until now the study of Cnidii Rhizoma, hemorrhage, brain waves, such as ischemic brain injury, analgesic, effect overcome of the stress from pregnancy melanin formation and inhibiting effects skin whitening have been published regarding this article. Cnidii Rhizoma demonstrates its different abilities depending on the characteristics. This paper reported that effect of Cnidii Rhizoma in Dongeuibogam blended prescriptions as main medicine. In addition, by analyzing data, we studied about utilizing of Cnidii Rhizoma. Methods : Cnidii Rhizoma in Dongeuibogam Prescriptions as the main ingredient was built with database of 202 prescriptions. Thus analyzed data was summarized in detail.(Table-1) If there is no difference in the title of the prescription but in other case the configuration information is different, formulations 1 and 2 were divided by the table. Results : The following results were reached through investigations on the prescriptions usikng Cnidii Rhizoma as a key component. 1. Prescriptions taking Cnidii Rhizoma as a monarch drug are utilized for 40 therapeutic purposes. In particular, 12.3% of prescriptions appear in the chapter of head, and 10.8% of those appear in the chapter of women, and 9.4% of eye, 8.9% of child, 6.4% of wind disease respectively. 2. Prescriptions utilizing Cnidii Rhizoma as the main ingredient are used in the treatment of headache, dizziness and pregnancy hemorrhage fetal movement, premature birth and they are also used for treating 131 different types of disease. 3. The dosage of Cnidii Rhizoma in formulas is from 2pun(about 0.75g) to 5don(nearly 18.75g), however 1don(nearly 3.75g) has been taken the most for clinical application. 4. We find out that according to herbs or prescriptions, Cnidii Rhizoma has a variety of functions such as ascending & descending of energy. Samultang is the most useful base prescription which used the Cnidii Rhizoma as the main component. Conclusion : These results suggest that, Cnidii Rhizoma once-amount use (don nearly 3.75g) 4g in head, gynecology, ophthalmology, pediatrics and paralysis disease associated with oriental medicine resource development can be considered to be widely used These results suggest that Cnidii Rhizoma was used most with 1 don(4g) and can be widely used for the resource development to the disease such as brain, gynecology, ophthalmologhy, pediatrics and wind-associated symptoms.