• Genomics & Informatics
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• v.14 no.4
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• pp.187-195
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• 2016

In genetic association studies with high-dimensional genomic data, multiple group testing procedures are often required in order to identify disease/trait-related genes or genetic regions, where multiple genetic sites or variants are located within the same gene or genetic region. However, statistical testing procedures based on an individual test suffer from multiple testing issues such as the control of family-wise error rate and dependent tests. Moreover, detecting only a few of genes associated with a phenotype outcome among tens of thousands of genes is of main interest in genetic association studies. In this reason regularization procedures, where a phenotype outcome regresses on all genomic markers and then regression coefficients are estimated based on a penalized likelihood, have been considered as a good alternative approach to analysis of high-dimensional genomic data. But, selection performance of regularization procedures has been rarely compared with that of statistical group testing procedures. In this article, we performed extensive simulation studies where commonly used group testing procedures such as principal component analysis, Hotelling's $T^2$ test, and permutation test are compared with group lasso (least absolute selection and shrinkage operator) in terms of true positive selection. Also, we applied all methods considered in simulation studies to identify genes associated with ovarian cancer from over 20,000 genetic sites generated from Illumina Infinium HumanMethylation27K Beadchip. We found a big discrepancy of selected genes between multiple group testing procedures and group lasso.

• Smart Structures and Systems
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• v.14 no.6
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• pp.1005-1030
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• 2014

The need for assessing dynamic response of typical industrial piping systems subjected to seismic loading motivated the authors to apply model reduction techniques to experimental dynamic substructuring. Initially, a better insight into the dynamic response of the emulated system was provided by means of the principal component analysis. The clear understanding of reduction basis requirements paved the way for the implementation of a number of model reduction techniques aimed at extending the applicability range of the hybrid testing technique beyond its traditional scope. Therefore, several hybrid simulations were performed on a typical full-scale industrial piping system endowed with a number of critical components, like elbows, Tee joints and bolted flange joints, ranging from operational to collapse limit states. Then, the favourable performance of the L-Stable Real-Time compatible time integrator and an effective delay compensation method were also checked throughout the testing campaign. Finally, several aspects of the piping performance were commented and conclusions drawn.

• Journal of Electrical Engineering and Technology
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• v.7 no.5
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• pp.778-783
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• 2012

The synthetic short-circuit making test to adequately stress the circuit breaker has been specified as the mandatory test duty in the IEC 62271-100. The purpose of this test is to give the maximum pre-arcing energy during making operation. And this requires the making operation with symmetrical short-circuit current that is established when the breakdown between contact gap occurs near the crest of the applied voltage. Also, if the interrupting chamber of circuit breakers is designed as the type of common enclosure or the operation is made by the gang operated mechanism that three-phase contacts are operated by one common mechanism, three-phase synthetic making test is basically required. Therefore, several testing laboratories have developed and proposed their own test circuits to properly evaluate the breaker performance. With these technical backgrounds, we have developed the new alternative three-phase making circuit.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.13 no.2
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• pp.95-101
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• 2020

In this paper, we consider a group testing (GT) framework which is to find a set of defective samples out of a large number of samples. To handle this framework, we propose a maximum product detection algorithm (MPDA) which is based on maximum a posteriori probability (MAP). The key idea of this algorithm exploits iterative detection to propagate belief to neighbor samples by exchanging marginal probabilities between samples and output results. The belief propagation algorithm as a conventional approach has been used to detect defective samples, but it has computational complexity to obtain the marginal probability in the output nodes which combine other marginal probabilities from the sample nodes. We show that the our proposed MPDA provides a benefit to reduce computational complexity up to 12% in runtime, while its performance is only slightly degraded compared to the belief propagation algorithm. And we verify the simulations to compare the difference of performance.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.35 no.1
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• pp.124-131
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• 2012

This paper presents a spreadsheet-based reliability prediction simulation framework for the conceptual product design stage to acquire system reliability information in timely manner. During early stage, reliability performance deals with both known and unknown failure rates and component-level and subsystem-level failure estimate to predict system reliability. A technique for performing life testing simulation using Excel spreadsheet has been developed under the such circumstances. This paper also discuss the results obtainable from this method such as reliability estimate, mean and variance of failures and confidence intervals. The resultant of this reliability prediction system is mainly benefitting small and medium-sized enterprise's field engineers.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.34C no.8
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• pp.49-63
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• 1997

This paper presents a current sensor that detects defects in CMOS integrated circuits using the current testing technique. The current sensor is built in a CMOS integrated circuit to test an abnormal current. The proposed circuit has a very small impact on the performance of the circuit under test during the normal mode. In the testing mode, the proposed circuit detects the abnormal current caused by permanent manufacturing defects and determines whether the circuit under test is defect-free or not. The proposed current sensor is simple and requires no external voltage and current sources. Hence, the circuit has less area and performance degradation, and is more efficient than any previous works. The validity and effectiveness are verified through the HSPICE simulation on circuits with defects.

• Journal of the Korean Society of Industry Convergence
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• v.25 no.4_2
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• pp.687-697
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• 2022

An automated system is needed for the effectiveness of non-destructive testing. In order to utilize the radiographic testing data accumulated in the film, the types of welding defects were classified into 9 and the shape of defects were analyzed. Data was preprocessed to use deep learning with high performance in image classification, and a combination of one-stage/two-stage method and convolutional neural networks/Transformer backbone was compared to confirm a model suitable for welding defect detection. The combination of two-stage, which can learn step-by-step, and deep-layered CNN backbone, showed the best performance with mean average precision 0.868.

• Fire Protection Technology
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• s.10
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• pp.5-8
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• 1991

This report is explained about test results of heat responsive links for fire protection service, such as fire dampers and fire doors, automatic fire suppression systems and so forth. The testing program was progressed divided by two testing items, external appearance test and performance test. The object of this report is present the problem which appear from the analysis of test results.

• Korean Journal of Clinical Pharmacy
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• v.27 no.3
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• pp.171-177
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• 2017

Objective: The study purpose was to develop a drug information leaflet for the elderly and to evaluate it with performance-based user-testing. Methods: We performed a stratified randomized controlled trial. We recruited 62 elderly patients with age of 65 or above who were taking antidiabetic medications at the point of participating and excluded those who suffered illiteracy. We randomly allocated them into the intervention group with a leaflet for the elderly and the control group with a leaflet for the general public. Main outcome measures were to 'be able to find information' and to 'be able to understand information.' We measured outcome variables by employing performance-based user-testing and analyzed data to find any differences between two groups with t-tests, chi-squared tests or Fisher's exact tests accordingly. Results: More participants in the intervention group understood how to store their medications than those in the control group (intervention group 93% vs. control group 70%; p=0.02). There were no significant differences in other information items between two groups. Mostly 'being able to understand information' was lower than 'being able to find information.' The gaps between two outcome variables were about 10% in the intervention group and about 18% in the control group. The lowest understanding was observed in information relating to drug names and their potential adverse events. Conclusion: Without providing personalized drug information, it might be hard for the elderly to improve their drug knowledge even with leaflets that were developed specifically for the elderly.

• Journal of Satellite, Information and Communications
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• v.2 no.2
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• pp.36-40
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• 2007

EGSE is used to check out satellite payload during the development prior to launch. The EGSE represented in this paper is a test system for Ka band communication transponder of COMS. The EGSE consist of two subsystems as CTS subsystem and PCTS subsystem. Communication Test subsystem (CTS) performs satellite transponder RF performance testing, data analysis and trending. Most of transponder RF performances are automatically tested by the CTS subsystem. Power, Command & Telemetry subsystem (PCTS) monitor telemetry messages from the transponder and send tele-commands to satellite transponder for the configuration change. PCTS also provide simulated S/C power to the transponder during the ground validation testing. The EGSE test functions are verified by the transponder simulator testing and will be used for the flight model transponders testing.