• Title/Summary/Keyword: Nuclear plant

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Gastroprotective Effect of Artemisia frigida Willd in HCl/Ethanol-induced Acute Gastritis (HCl/에탄올로 유발된 급성 위염에서 Artemisia frigida Willd의 위장 보호 효과)

  • Oh, Min Hyuck;Lee, Se Hui;Park, Hae-jin;Shin, Mi-rae;Sharav, Bold;Roh, Seong-soo
    • Korean Journal of Pharmacognosy
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    • v.52 no.4
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    • pp.242-250
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    • 2021
  • Artemisia frigida Willd (AW, Fringed sagewort), which is widespread in Mongolia, is a well-known medicinal plant as a member of the Compositae family. This study aims to explore the gastroprotective effect of water extract of AW on 150 mM HCl/60% ethanol-induced acute gastritis in 5 week old male ICR mice. Total polyphenols, total flavonoid contents, and anti-oxidant activity in vitro in AW were evaluated. First, the gross area of gastric mucosal damage was measured. Then western blot analysis was conducted to determine the possible mechanisms of action underlying the effects of AW. AW administration decreased gastric mucosal damage. Moreover, the group with AW treatment effectively inhibited nicotinamide adenine dinucleotide phosphate (NADPH) oxidase expression associated with oxidative stress. AW treatment enhanced an anti-oxidant effect through the increase of anti-oxidant proteins. Besides, the increased expressions of inflammatory cytokines induced by nuclear factor-kappa B (NF-κB) activation are alleviated through AW treatment. Taken together, AW exerted a gastroprotective effect against gastric mucosal damage. These results indicate that AW could have the potential used as a natural therapeutic drug for the treatment of acute gastritis.

A Study on Retrospective of External Radiation Exposure Dose by Optically Stimulated Luminescence of Smart Chip Card (스마트칩 카드을 이용한 광 자극 발광 특성 연구)

  • Park, Sang-Won;Yoo, Se-Jong
    • Journal of radiological science and technology
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    • v.42 no.5
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    • pp.379-385
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    • 2019
  • Radiation is used for various purposes such as cancer therapy, research of industrial and drugs. However, in case of radiation accidents such as terrorism, collapsing nuclear plant by natural disasters like Fukushima in 2011, very high radiation does expose to human and could lead to death. For this reason, many people are concerning about radiation exposures. Therefore, assessment and research of retrospective radiation dose to human by various path is an necessary task to be continuously developed. Radiation exposure for workers in radiation fields can be generally measured using a personal exposure dosimeter such as TLD, OSLD. However, general people can't be measured radiation doses when they are exposed to radiation. And even if radiation fields workers, when they do not in possession personal dosimeter, they also can't be measured exposure dose immediately. In this study, we conduct retrospective research on reconstruction of dose after exposure by using smart chip card of personal items through Optically Stimulated Luminescence (OSL). The OSL signal of smart chip card shows linear response from 0.06 Gy to 15 Gy and results of fading rate 45 %, 48% for 24 and 48 hours due to the natural emission of radiation in sample, respectively. The minimum detectable limit (MDD) was 0.38 mGy. This values are expected to use as correction values for reconstruction of exposure dose.

In Vitro Experiment to Evaluate 137Cs Dissolution in the Digestion Process of Mushrooms

  • Nishiono, Kanoko;Yamanishi, Hirokuni
    • Journal of Radiation Protection and Research
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    • v.45 no.4
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    • pp.154-162
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    • 2020
  • Background: Several studies have reported that wild mushrooms contain high amounts of radioactive cesium (137Cs). After the Fukushima Daiichi Nuclear Power Plant Accident, a significantly high concentration of 137Cs has been detected in wild mushrooms, and their consumption may be the cause of the chronic internal exposure of local consumers to radioactivity. Therefore, an accurate evaluation of the internal radioactivity resulting from mushroom ingestion is needed. Materials and Methods: The 137Cs elution rate through the cooking and digestion stages was evaluated using in vitro experiments. The edible mushroom Pleurotus djamor was taken as a sample for the experiments. The mushrooms were cultivated onto solid media containing 137Cs. We evaluated the internal dose based on the actual conditions using the elution rate data. For various cooking methods, the results were compared with those of other wild edible mushrooms. Results and Discussion: From the elution experiment through cooking, we proved that 25%-55% of the 137Cs in the mushrooms was released during soaking, boiling, or frying. The results of a simulated digestion experiment after cooking revealed that almost all the 137Cs in the ingested mushrooms eluted in the digestive juice, regardless of the cooking method. The committed effective dose was reduced by 20%-75% when considering the dissolution through the cooking process. Conclusion: We found that cooking lowers 137Cs concentration in mushrooms, therefore reducing the amount of radioactivity intake. Besides, since there were differences between mushroom types, we demonstrated that the internal exposure dose should be evaluated in detail considering the release of 137Cs during the cooking stages.

Development of Multiplier Operator for Input Signal Control of Electronic Circuits (전자회로의 입력신호 제어용 곱셈연산기 개발)

  • Kim, Jong-Ho;Chang, Hong-Ki;Kwon, Dae-Shik;Che, Gyu-Shik
    • Journal of Advanced Navigation Technology
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    • v.22 no.2
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    • pp.154-162
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    • 2018
  • The multiplier circuit is necessary to estimate degradation status of electronic cards in nuclear power plant, but its accuracy is not easy in processing those functions to multiply two input signals. What is important in multiplier circuit is that the multiplication result must be accurate and its linearity must be perfect. We developed and proposed excellent linearity multiplier circuit using operational amplifiers and transistor characteristics, and then proved its validity in this paper. We have made efforts to eliminate nonlinearity components of semiconductors with this circuit in order to ensure excellent linearity of developed multiplier circuit. We conducted multiplication operations through simulation, applying adequate values to each component in order to verify the circuit composed of that method. We showed step-by-step output signals, and then compared the logical analyses and measuring results as simulation results. We confirmed that this method is superior to existing multiplication or linearity.

Hydrogen Recombination over Pt/TiO2 Coated Ceramic Honeycomb Catalyst (Pt/TiO2 코팅 세라믹 허니컴 촉매를 이용한 수소 제어)

  • Kang, Youn Suk;Kim, Sung Su;Seo, Phil Won;Lee, Seung Hyun;Hong, Sung Chang
    • Applied Chemistry for Engineering
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    • v.22 no.6
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    • pp.648-652
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    • 2011
  • Passive autocatalytic recombiner (PAR) is considered as an explosive gas control system in operating NPP plants. This work investigates and evaluates hydrogen recombination performance over manufactured $Pt/TiO_2$ catalysts. When the space velocity increases, the hydrogen conversion decreased, while hydrogen depletion rate (g/sec) increases highly in $35000{\sim}100000hr^{-1}$ Gas Hourly Space Velocity (GHSV). Hydrogen conversion and depletion rate with Pt loading is investigated. As a result, there were no differences in the hydrogen conversion, but exothermic heating rate (K/sec) is increases as Pt loading increases. The catalyst showes a high hydrogen conversion efficiency of 80% under atmospheric conditions.

Processing of Low Tin Zr-1Nb-0.69Sn-0.11Fe Alloy Tubes and Effect of Final Heat Treatment on Their Mechanical and Corrosion Properties (저 Sn 함유 Zr-Nb-Sn-Fe 합금 튜브 제조 및 최종 열처리 온도에 따른 기계적/부식특성 변화)

  • Cho, Nam Chan;Lee, Jong Min;Hong, Sun Ig
    • Korean Journal of Metals and Materials
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    • v.49 no.1
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    • pp.17-24
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    • 2011
  • To investigate the relationship between heat treatment in zirconium alloy tubing process and metallurgical characteristics of Zr-1Nb-0.69Sn-0.11Fe alloy tubes, mechanical and oxidation behaviors of tubes heat treated at different temperatures after the final pilgering were investigated. The stress strain curves exhibited the saturation behaviors in all heat treatment conditions ($460{\sim}600^{\circ}C$) in this study with the onset strain of saturation increased with increase of post-pilgering annealing temperature. The strength fell off rapidly with increasing annealing temperature. The ultimate strength of the low tin Zr-1Nb-0.69Sn-0.11Fe alloy with slightly higher iron and oxygen contents in this study was found to be higher than Zr-1Nb-1Sn-0.1Fe alloy. The oxidation experiments in steam condition revealed that the corrosion resistance of low tin Zr-1Nb-0.69Sn-0.11Fe alloy was better than the Zr-1Nb-1Sn-0.1Fe alloy with a higher Sn content. The weight gain of low tin Zr-1Nb-0.69Sn-0.11Fe alloy tubes gradually increased with the increasing annealing temperature possibly due to the decreased Nb content in the matrix because of the formation of ${\beta}-Nb$ particles.

Estimation of the carryover effect of Japanese radiation-related news on domestic seafood consumption (일본 방사능 관련 보도가 국내 수산물 소비액에 미치는 이월효과 추정)

  • Jung, Ji-Sook;Lee, Hyo-jin;Kim, Seung Gyu
    • Journal of the Korea Convergence Society
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    • v.13 no.4
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    • pp.373-381
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    • 2022
  • The Fukushima nuclear power plant water spill caused by the Great East Japan Earthquake in March 2011 raised fears about radiation exposure through consumption of radioactively contaminated seafood. The Korean government banned importing agricultural and fishery products from eight prefectures near Fukushima, but the related news were continuously reported partly due to the WTO dispute with Japan, which seems to have aggravated consumers' anxiety about seafood. In this study, data on daily purchases of products for three years (2018-2020) were collected and the effect of Japanese radiation-related news on domestic consumers' purchases of seafood was estimated using a polynomial lag distributed model. As a result of the analysis, it was found that radiation-related news had a statistically significant negative effect on the purchase of seafood on the 5th and 6th days after exposure to consumers through the media. It captures the carryover effect in which consumers' perceptions are reflected in the purchase of seafood after exposure to related news.

Development of an Objective Judgement Procedure for Determining Involvement of Violation-Type Unsafe Acts caused Industrial Accidents (사고 유발 불안전행동의 위반 여부에 대한 객관적 판단절차 개발)

  • Lim, Hyeon Kyo;Ham, Seung Eon;Bak, Geon Yeong;Lee, Yong Hee
    • Journal of the Korean Society of Safety
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    • v.37 no.2
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    • pp.35-42
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    • 2022
  • When an accident occurs, the associated human activity is typically regarded as a "human error," or a temporal deviation. On the other hand, if the accident results in a serious loss or if it evokes a social issue, the person determined to be responsible may be punished with a "violation" of related laws or regulations. However, as Heinrich stated, it is neither appropriate nor reasonable in terms of probability theory and cognitive science to distinguish whether it is a "human error" or a "violation" with a criterion of resultant accident severity. Nonetheless, some in society get on the social climate to strengthen regulations on workers who have caused accidents, especially violations. This response can present a social issue due to the lack of systematic judgment procedure which distinguishes violations from human errors. The purpose of this study was to develop an objective and systematic procedure to assess whether workers' activities which induced industrial accidents should be categorized as violations rather than human errors. Various analysis techniques for the determination of violation procedure were investigated and compared using an analysis approach method. An appropriate technique was not found, however, for judging the culpability of intentional violations. As an alternative, this study developed the process of creating violations, based on cognitive procedure, as well as the criteria to determine and categorize an activity as a violation. In addition, the developed procedure was applied to cases of industrial accidents and nuclear power plant issues to test its practical applicability. The study demonstrated that the proposed model could be used to determine the existence of a violation even in the case of multiple workers who work simultaneously.

Protective Effect of Cotoneaster mongolicus Pojark. Extract in HCl/ethanol-induced Gastritis Mice (Cotoneaster mongolicus Pojark. 추출물의 HCl/ethanol로 유발된 위염 mice에 대한 보호효과)

  • Choi, Jeong Won;Lee, Jin A;Shin, Mi-Rae;Park, Hae-jin;Roh, Seong-Soo
    • Korean Journal of Pharmacognosy
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    • v.53 no.3
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    • pp.153-161
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    • 2022
  • Cotoneaster mongolicus Pojark. (CM), in the family Rosaceae is an endemic plant to the Mongolian region (its name: Moнroл чapraй). In Mongolia, Cotoneaster species as a crude drug is mainly used for inflammatory diseases, diarrhea, and stomach indigestion. In this study, we evaluated the gastro-protective activity underlying mechanism of CM. For in vivo experiments, mice were divided into 5 groups; normal mice (Normal), gastritis mice (Control), gastritis mice treated with sucralfate 10 mg/kg (SC), gastritis mice treated with CM 100 mg/kg (CML), gastritis mice treated with CM 200 mg/kg (CMH). Gastritis was provoked by HCl/ethanol (60% ethanol in 150 mM HCl). After oral administration of each drug, HCl/ethanol was orally administered 90 mins later to induce gastritis. CM alleviated the damage to the gastric mucosa caused. As a result of confirming the expression of protein in gastric tissue through western blot, CM significantly reduced the expression of NF-κB activated due to gastritis. Also, it significantly modulated the Nrf2-Keap1 pathway. These results indicate that CM not only inhibits the nuclear metastasis of NF-𝛋B but also modulates the Nrf2-Keap1 pathway to relieve inflammation of the gastric mucosa.

Economic Analysis and Comparison between Low-Power and High-Power SOEC Systems (저출력 및 고출력 SOEC 시스템의 경제성 분석 비교)

  • TUANANH BUI;YOUNG SANG KIM;DONG KEUN LEE;KOOK YOUNG AHN;YONGGYUN BAE;SANG MIN LEE
    • Journal of Hydrogen and New Energy
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    • v.33 no.6
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    • pp.707-714
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    • 2022
  • Hydrogen production using solid oxide electrolysis cells (SOEC) is a promising technology because of its efficiency, cleanness, and scalability. Especially, high-power SOEC system has received a lot of attention from researchers. This study compared and analyzed the low-power and high-power SOEC system in term of economic. By using revenue requirement method, levelized cost of hydrogen (LCOH) was calculated for comparison. In addition, the sensitivity analysis was performed to determine the dependence of hydrogen cost on input variables. The results indicated that high-power SOEC system is superior to a low-power SOEC system. In the capital cost, the stack cost is dominant in both systems, but the electricity cost is the most contributed factor to the hydrogen cost. If the high-power SOEC system combines with a nuclear power plant, the hydrogen cost can reach 3.65 $/kg when the electricity cost is 3.28 ¢/kWh and the stack cost is assumed to be 574 $/kW.