• 생명과학회지
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• 제11권2호
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• pp.121-125
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• 2001

Some attempts were made to investigate the biological characterisitcs of the green rice leafhopper(GLH) , Nepthotettix cincticeps Uhler in terms of nymphal development, emergence ratio. preovipositional period, growth index, adult longevity and fecundity fed on rice cultivar, Chucheongbyeo with no resistance gene and water foxtail, Alpecurus aequalis Sobol. var. amurensis Ohwi at 20 and $25^{\circ}C$ with a 16L;8D photoperiod. Development period of nymph on rice cultivar and water foxtail at $25^{\circ}C$ was shorter than that at 2$0^{\circ}C$ by twofold. The nymphal period of female was about one day longer than that of male. The mean emergence ratio of female and male on rice cultivar and water foxtail was 40.0, 76.7, 38.3, 73.3% at 20 and $25^{\circ}C$, respectively. Preovipositional period on rice cultivar and water foxtail at $25^{\circ}C$ was shorter that at 2$0^{\circ}C$ by twofold. Growth index on rice cultivar adn water foxtail at $25^{\circ}C$was higher than that at 2$0^{\circ}C$ by fourfold. Under the 20 and $25^{\circ}C$ condition, the longevity of female and male was longer on water foxtail than on rice cultivar, but the fecundity of GLH was higher on rice cultivar than on water foxtail. In conculsion, water foxtail seems to be adequate for spring host of GLH.

• 동의생리병리학회지
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• 제25권4호
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• pp.721-727
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• 2011

The purpose of this study was to review the current situation of Sasang typology studies and get a recommendation for ameliorating it by systematically reviewing articles published in Korea from 2000 to 2009. Six hundred seventy-seven articles were found by searching the representative Korean databases such as KISS, RISS, KISTI, DBPIA, NDSL and also by hand search. Yearly analysis was performed by academic field, journal, author and affiliation, type of article and content. The analysis showed that the number of published articles has increased from 61 in 2000 to 86 in 2009. 607(89.6%) were related to medical field, 627(92.6%) were published in Korean Citation Index-listed journals, and 413(68.8%) were published in the Journal of Sasang Constitutional Medicine. The authors listed on one article were 3.98 persons and affiliated in 1.66 departments in average. Sixty six percents are for the clinical studies or case reports, and twenty-five for Sasang type diagnosis. This study showed that more active collaborations with diverse research fields and various research methods are needed for the improvement of Sasang typology studies and the scope expansion of Korean traditional medicine.

• 대한한의학방제학회지
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• 제32권3호
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• pp.247-261
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• 2024

Objectives : Zuojin Pill, recognized as an effective herbal remedy, has undergone investigation for its potential in alleviating symptoms like indigestion, vomiting, and abdominal distension. The purpose of this study was to investigate the mechanism of digestive function activation through network pharmacology, particularly focused on improving functional dyspepsia. Methods : The two components, Coptidis Rhizoma and Evodiae Fructus, constituting Zuojin Pill were analyzed based on broad information on chemical and pharmacological properties, confirming 40 active compounds and 115 digestive-related molecular targets. Concentration analysis revealed impacts on various pathways related to digestive functions. Results : According to network pharmacological analysis of Zuojin Pill, quercetin and beta-sitosterol were exhibited relatively numerous targets, suggesting their potential significance in the therapeutic activity of Zuojin Pill and by a Protein-Protein Interaction (PPI) network, JUN, RELA, MAPK1, HSP90AA1, TP53, TNF, AKT1, IL6, MAPK14, ESR1, FOS, MYC were identified. Also, berberine exhibited the highest contribution index (92.58%), indicating that this compound may be a major contributor to the digestive activity of Zuojin Pill. Additionally, functional interaction analysis by GeneMANIA indicated that targets of Zuojin Pill could functionally interact through various mechanisms, implying similarities in pharmacological roles. Conclusions : These findings contribute valuable insights into the digestive function activation mechanism and highlight the therapeutic potential of Zuojin Pill in improving functional dyspepsia.

• 한국한의학연구원논문집
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• 제18권2호
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• pp.55-64
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• 2012

Objectives: This study was performed to review the use of statistical analysis methods for the Traditional Korean Medicine studies listed on the Korea Citation Index from 1999 to 2008. Methods: A total of 4217 studies published on four journals of Traditional Korean Medicine were screened and 2682 articles using statistical methods were selected for the review. The selected studies were analysed according to their published year, statistical method and statistical package for use. Results: Statistical methods were used steadily in 64.6% of the articles after 2001, the most used statistical methods(57%) were mean difference comparison between 2 groups. The number of statistical methods mostly used in one article was identified as one in 1931 articles (72.0%). Duncan (36.8%) and Tukey (26.5%) were used for the ANOVA post hoc analysis. SPSS was most frequently used 68% out of Statistical package programs.(the number of mean difference comparison among more than 3 groups was continuously increasing and that makes post hoc being used. skills of statistical methods need to be diversified.) Conclusion: The interest on the proper use of statistical analysis in the research is increasing. This study will contribute to the Evidence-based Teaching on research methodology in Traditional Korean Medicine.

• 동의생리병리학회지
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• 제23권4호
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• pp.765-771
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• 2009

The medical informatics for clustering Sasang types with collected clinical data is important for the personalized medicine, but it has not been thoroughly studied yet. The purpose of this study was to examine the usefulness of neural network data mining algorithm for traditional Korean medicine. We used Kohonen neural network, the Self-Organizing Map (SOM), for the analysis of biomedical information following data pre-processing and calculated the validity index as percentage correctly predicted and type-specific sensitivity. We can extract 12 data fields from 30 after data pre-processing with correlation analysis and latent functional relationship analysis. The profile of Myers-Briggs Type Inidcator and Bio-Impedance Analysis data which are clustered with SOM was similar to that of original measurements. The percentage correctly predicted was 56%, and sensitivity for So-Yang, Tae-Eum and So-Eum type were 56%, 48%, and 61%, respectively. This study showed that the neural network algorithm for clustering Sasang types based on clinical data is useful for the sasang type diagnostic test itself. We discussed the importance of data pre-processing and clustering algorithm for the validity of medical devices in traditional Korean medicine.

• 사상체질의학회지
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• 제28권3호
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• pp.246-257
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• 2016

Objectives The Sasang Personality Questionnaire (SPQ) measures the Yin-Yang temperament of Sasang typology with proven structural and clinical validity in adults, however it was not examined with teenagers. The purpose of this study was to validate the biopsychological structure of SPQ in middle school students.Methods 681 Korean high school students (356 boys and 325 girls) completed SPQ, Junior version of Temperament and Character Inventory (JTCI), and height and weight measures. The correlation between SPQ and JTCI subscales were examined, and the differences of SPQ and JTCI subscales, Body Mass Index (BMI) and Pondera Index (PI) among high (30%), middle (40%), and low (30%) SPQ total score groups were investigated with Analysis of Variance (ANOVA). The profile analysis was also performed to compare JTCI subscale profiles of three SPQ total score groups.Results The SPQ score was significantly (p<0.001) correlated positively with JTCI Novelty-Seeking and negatively with JTCI Harm-Avoidance. The JTCI Novelty-Seeking score of high SPQ group was significantly (p<0.001) higher than that of low SPQ group, and the JTCI Harm-Avoidance score of low SPQ group was significantly higher than that of high SPQ group. The JTCI subscale profiles for three SPQ groups were significantly different for boys and girls. Significant correlations or differences for the PI and BMI among SPQ groups were not found.Conclusions This study presented that the biopsychological structure of SPQ is robust as shown in adults. The SPQ would be a useful clinical measures of Sasang typology in pediatric patients.

• Journal of Periodontal and Implant Science
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• 제51권3호
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• pp.163-178
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• 2021

Purpose: The aim of this study was to evaluate clinical factors affecting the longevity of fixed retainers and the influence of fixed retainers on periodontal health in periodontitis patients. Methods: In total, 52 patients with at least 2 years of follow-up after periodontal and orthodontic treatment were included in this study. After scaling and root planing, orthodontic treatment with fixed appliances or clear aligners was performed. Fixed retainers with twist-flex stainless steel wires were bonded to the palatal or lingual sides of anterior teeth. Changes in clinical parameters, including the plaque index, gingival index, calculus index (CI), probing pocket depth, and radiographic bone levels, were evaluated before bonding of fixed retainers and at a 12-month follow-up. Cumulative survival rates (CSRs) for retainer failure were evaluated according to sex, site, CI, stage of periodontitis, and the severity of the irregularity with the log-rank test and hazard ratios (HRs). Results: Twelve months after bonding of fixed retainers, improvements were observed in all clinical parameters except CI and radiographic bone gain. The overall CSR of the retainers with a CI <1 at the 12-month follow-up after bonding of fixed retainers was significantly higher than that of the retainers with a CI ≥1 at the 12-month follow-up (log-rank test; P<0.001). Patients with stage III (grade B or C) periodontitis had a higher multivariate HR for retainer failure (5.4; 95% confidence interval, 1.22-23.91; P=0.026) than patients with stage I (grade A or B) periodontitis. Conclusions: Although fixed retainers were bonded in periodontitis patients, periodontal health was well maintained if supportive periodontal treatment with repeated oral hygiene education was provided. Nonetheless, fixed retainer failure occurred more frequently in patients who had stage III (grade B or C) periodontitis or a CI ≥1 at 12-month follow-up after bonding of fixed retainers.

• 한국환경생태학회지
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• 제16권3호
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• pp.223-232
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• 2002

자연생태계의 보전을 위한 지역구분을 위하여 백두대간(피재-도래기재) 구간을 조사한 식생조사 자료를 바탕으로 식생의 보전가치를 식생지수라는 것으로 수치화하는 방법을 제시해 보고자 한다. 식생지수는 생물다양성, 임분의 보전가치, 환경의 청정성, 임분의 역사성 입지의 생산성 등을 바탕으로 수치화하였다. 식생지수는 백두대간 관리범위 설정에 이용될 수 있을 것이라 사료된다. 식생지수 I의 경우 총 113개의 조사지 중에서 59개 지역 52.2%가 핵심지역에 속하고, 34개 지역 30.1%, 20개 지역 17.7%가 각각 완충지역과 전이지역에 속하는 것으로 나타났다. 식생지수II의 경우 49개 지역 43.4%가 핵심지역에 속하고, 38개 지역 33.6%, 26개 지역 23.0%가 각각 완충지역과 전이지역에 속하는 것으로 나타났다.

• 대한한방소아과학회지
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• 제27권2호
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• pp.1-10
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• 2013

Objectives The aim of this study was to explore the effect of parental attitude on the behavioral problems in children who visited the traditional Korean pediatrics clinic. Methods The subjects were consist of 190 outpatients ($56.6{\pm}12.9$ months) and their mother. The Behavior problems of children were measured with Korean version of Child Behavior Checklist for Ages 1.5-5 (K-CBCL1.5-5) while parental perception of child vulnerability, parent overprotection, parenting stress were measured by Child Vulnerability Scale (CVS), Parent Protection Scale (PPS), Korean-Parenting Stress Index-Short Form scale (K-PSI-SF), respectively. Correlation and multiple regression were conducted for the analysis. Results Significant correlations between child total problems score and child vulnerability (r=.272, p<.001), parent overprotection (r=.243, p=.001), and parenting stress (r=.597, p<.001) were reported. Multiple regression analysis revealed that the parenting stress (${\beta}$=.548, p<.001) was a major predictor for the child behavior problems rather than child vulnerability and parent overprotection. Conclusions It was shown that the parenting stress has a significant influence on the emotional and behavioral development of children. These results can be useful for improving clinical diagnosis and treatment in traditional Korean pediatrics.

• 한국작물학회지
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• 제58권4호
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• pp.432-438
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• 2013

This study was conducted to compare seed viability among 42 species after ten years of storage in the midterm storage complex ($4^{\circ}C$, 30-40% RH) at the National Agrobiodiversity Center (NAC) Korean genebank maintained by the Rural Development Administration (RDA), Republic of Korea and to suggest the relative seed longevity and suitable monitoring intervals. The germination data from initial tests and after ten years of storage were compared to measure changes in viability during storage. The decline in seed viability varied greatly among seeds from -11.5% for Triticum sp. to 80% for melon. Coriander, crowndaisy, safflower, cosmos, Chinesebellflower, waxgourd, melon, castorbean, Welch-onion, hollyhock, wild barley, and tallfescue showed significant decreases in viability of 34.2%, 73.4%, 36.5%, 30.0%, 40.2%, 71.3%, 80.0%, 65.9%, 45.5%, 51.4%, 53.0%, and 33.5%, respectively. Gardenpea, soybean, perilla, onion, wild rice, Italian-ryegrass, and pepper showed a 15-30% decline in viability, while the viability of morningglory, adzukibean, maize, and Capsicum sp. decreased by 15% to 5%. Chicory, radish, Chinese-cabbage, bottlegourd, watermelon, cucumber, pumpkin, Cucurbita sp., groundnut, kidneybean, clubwheat, sesame, wheat, Triticum sp., rice, barley, orchardgrass, buckwheat, and wild tomato showed changes in viability of <5%. The changes in storage viability also varied within families. The wild types of rice and barley showed rapid viability loss and presented different aspects from cultivars. Since seed viability of species, classified as index 1 or 2, showed germination losses >15% after ten years of storage, a viability test should be conducted with five year intervals, while species with germination loss of <15% (in index 3 or 4) can be retested at ten year intervals.