• Journal of Veterinary Clinics
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• v.17 no.1
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• pp.252-255
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• 2000

A 13.5kg, 15-year-old male mongrel dog with anemia, anorexia, vomiting and abdominal distension was referred to the Veterinary Medical Center of the Tokyo University. Radiographic and ultrasonographic findings indicated primary splenic tumor. The tumor was located at body of the spleen, which was surgically removed by splenectomy. Histopathological examination of the mass revealed sarcoma type tumor derived from the mesenchymal origin. The patient was in good health after surgery but suddenly showed abdominal distension on the 3 months after. Radiographic findings indicated abdominal neoplasms. The 2nd operation was performed and removed the recurrent mast but suddenly died on the 4th day. Histopathological examination of the tumor was myxosarcoma.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.429-440
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• 1996

In order to know morphological changes on the female genital organs by Ivermectin(IVM) administration, the histopathological observation was carried out in the organs of rat and mouse treated with the overdose of IVM. In the microscopical findings of the uterus, there were many mitotic figures, epithelial hyperplasia and papillary foldings in the endometrial surface. The increased prevalance of uterine glands, uterine epithelia and glands hyperplasia were markedly presented on diverse patterns adenoma-like structure and single nodular or multiple polyp-like adenoma. In ovary, primary and mature follicles were decreased in number, and hypoplasia of ovarian follicles, atretic follicles, follicular cysts and ovarian atropy were observed. It was considered that IVM administration resulted in follicular hypoplasia and atropy of ovary, and hyperplasia of uterine gland and endometrial surface epithelium might be transformed to neoplasia of glandular structures.

• Korean Journal of Veterinary Research
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• v.36 no.2
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• pp.441-445
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• 1996

A case of necrotizing meningoencephalitis was described in a 3-year-old female pug dog. Significant histopathological changes were confined to the brain. Histopathologically, brain lesion of the pug dog was characterized by (1) severe lymphocyte, plasma cell and macrophage infiltration in the meninges and gray and white matter of the cerebral hemisphere, (2) perivascular mononuclear cell cuffing and (3) focal polioencephalomalacia in the gray matter of cerebrum. Replicate sections of the brain and lung were negative for fungal infection, canine distemper and toxoplasmosis on PAS stain and immunohistochemistry, respectively. Based on clinical signs, histopathological and immunohistochemical studies, this case was diagnosed as necrotizing meningoencephalitis in pug dog that had not been preriously described in Korea.

• The Journal of the Korean dental association
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• v.9 no.11
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• pp.701-704
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• 1971

The authors have studied histopathologically, based with symptoms, on 51 aged woman who treated in infirmary hospital of dental college of Seoul National University. The results are as follows: 1. Symptoms of patient were swelling of lower left mandible, gingival enlargement, ulceration and severe bleeding. 2. We observed characteristic features on the blood test such as decreased leukocytes with severe decrease of granular leuckocytes and sudden increase of lymphocytes. 3. On the histopathological studies, we observed severe destruction of gingival tissue with few granular leukocytic infiltration, but displaced with massive lymphochtic infiltration.

• Journal of Veterinary Clinics
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• v.16 no.2
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• pp.321-327
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• 1999

This study was performed to examine the clinical, serological, ultrasonographic and pathological findings in dogs with acute liver disease induced by tetrachlorethylene at 4 times of anthelminthic oral dose. The results obtained through this experiment could be summarized as follows: 1. The dogs administered with tetrachlorethylene, revealed decreased body weight, and showed lethargy and depression. 2. In serological findings, bilirubin values slightly increased, AST and ALT was decreased at 1∼3 days, and after that time increased according to the lapse of days, and revealed the highest at 5 days, and decreased to normal values at 6 days. 3. In ultrasonographic findings, branches of the portal vein were increased, the echodensity of the liver parenchyma was decreased at early stage, and increased at mid stage, and decreased at last stage. 4. In histopathological findings, necrosis of parenchymal cell, and perivascular hemorrhage were observed more severely at 6 days, as compared with 3 days. There results suggest that ultrasonographic examination is considered to be a more simple, rapid, non-invasive and useful diagnostic method for acute liver parenchymal lesion.

• Korean Journal of Veterinary Research
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• v.35 no.4
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• pp.785-791
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• 1995

The kidney, heart and lung were examined of cats fallen sick lower urinary tract disease(LUTD). There cases typically clinical findings were urinary retention, hematuria, dehydration, cytoplegia and uremia. It is believed that these histopathological and clinical findings resulted from the struvite crystal thrombus in ureter. But we have many factors of an unsolved problem on LUTD. Accordingly, this LUTD demands to process of pathological diposition.

• Imaging Science in Dentistry
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• v.41 no.1
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• pp.29-33
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• 2011

A 46-year-old man was referred to our hospital for treatment, complaining of swelling on the right mandibular molar region. Radiographic examination revealed a well defined multilocular radiolucent lesion with root resorption of right lower anteriors and molars. Following biopsy, a diagnosis of unicystic ameloblastoma of mural type was made and hemimandibulectomy was performed under general anesthesia. Histopathological examination of the surgical specimen exhibited a unicystic ameloblastoma of luminal, intraluminal, and mural type. Intraluminal proliferation was of plexiform pattern and mural proliferation showed unusual histopathological findings, which revealed follicular, acanthomatous areas coexisted with desmoplastic areas. This mural picture was similar to the so-called 'hybrid lesion of ameloblastoma', whose biological profile is not elicited due to the lack of adequate published reports. Two years follow up till date has not revealed any signs of recurrence.

• Toxicological Research
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• v.17 no.1
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• pp.11-15
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• 2001

This study was carried out to evaluate the irritant potential of A mouthwash in hamster cheek pouch. The test substances were applied twice daily to right pouches of hamsters for 14 consecutive days. Animals were administered with A mouthwash, Listerine, saline and control solution, respectively. In order to evaluate the irritant potential in mucosa of hamster cheek pouch, we observed clinical signs, mortality, body weight changes and gross and histopathological findings for 14 days. In all groups, there were neither dead animals nor significant changes of body weights. In addition, there were no differences between saline and A mouthwash treated group in gross and histopathological findings. Therefore, these results suggest that there was no irritant potential of A mouthwash in hamster cheek pouch.

• Proceedings of the Korean Society of Toxicology Conference
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• 2002.05a
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• pp.126-126
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• 2002

Histopathological changes and cadmium accumulations in the gills were investigated in crucian carp(Carassius auratus) exposed to 0, 0.01, 0.1, 0.5mg/$\ell$ cadmium(Cd) concentrations for 25 days. After 25 days of exposure, cadmium accumulations increased in each of the different exposure concentrations.(omitted)

• Korean Journal of Veterinary Pathology
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• v.7 no.1
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• pp.27-41
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• 2003

The purpose of this study was to evaluate the effect of a subsequent infection of porcine reproductive and respiratory syndrome(PRRS) virus to pigs with A. pleuropneumonia in pigs. Twenty three 7-weeks-old commercial pigs were infected with PRRS virus and/or A. pleuropneumoniae serotype 5 intratracheally. Feed conversion, clincal signs, gross and histopathological lesions and immunohistochemical findings were examined. 1. Feed conversion ratio in dual-infected pigs with PRRS virus and A. pleuropneumoniae were higher than that of single- infected pigs with PRRS virus or A. pleuropneumoniae. 2. Dual-infected pigs with PRRS virus followed by A. pleuropneumoniae showed more severe clinical signs and gross, histopathological and immunohistochemical pulmonary lesions. The results indicated that dual infections with PRRS virus and A. pleuropneumoniae caused more severe respiratory lesions and growth retardation in pigs than single infection with PRRS virus or A. pleuropneumoniae.