Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Clinical and Ultrasonographic Studies for the Liver Lesion Induced by Tetrachlorethylene in Dogs

개에서 Tetrachlorethylene에 의해 유발된 간장 병변의 임상 및 초음파학적 연구

  • 김영범 (충남대학교 수의과대학) ;
  • 김명철 (충남대학교 수의과대학)
  • Published : 1999.12.01
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Abstract

This study was performed to examine the clinical, serological, ultrasonographic and pathological findings in dogs with acute liver disease induced by tetrachlorethylene at 4 times of anthelminthic oral dose. The results obtained through this experiment could be summarized as follows: 1. The dogs administered with tetrachlorethylene, revealed decreased body weight, and showed lethargy and depression. 2. In serological findings, bilirubin values slightly increased, AST and ALT was decreased at 1∼3 days, and after that time increased according to the lapse of days, and revealed the highest at 5 days, and decreased to normal values at 6 days. 3. In ultrasonographic findings, branches of the portal vein were increased, the echodensity of the liver parenchyma was decreased at early stage, and increased at mid stage, and decreased at last stage. 4. In histopathological findings, necrosis of parenchymal cell, and perivascular hemorrhage were observed more severely at 6 days, as compared with 3 days. There results suggest that ultrasonographic examination is considered to be a more simple, rapid, non-invasive and useful diagnostic method for acute liver parenchymal lesion.

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References

  1. Vet radiol & Ultrasound v.35 Ultrasonographic features of diffuse hepatocelluar disorders in diary cattle Acorda,J.;Yamada,H.
  2. Res In Vet Sci v.20 Plasma bile acid elevation following CC14 induced liver damage in dogs, sheep, calves and ponies Anwer,M.S.;Engelking,L.R.;Gronwall,R.;Klentz,R.D.
  3. J Vet Int Med v.6 Ultrasonography of diffuse liver Biller,D.S.;Kantrowits,B.;Miyabuyashi,T.
  4. Libid Echocardiography. Congenital heart disease Bonagura,J.D.;Hering,D.S.
  5. Vet Radiol & Ultrasound v.36 Anatomy of the portal vein and hepatic veins of the dog : A basis for systematic evaluation of the liver by ultrasography Carlisle,C.H.;Heath,J.J.
  6. J am Anim Hosp Assoc v.17 Diagnostic real time ultrasonography of the lever of the dog and cat Cartee,R.E.
  7. Transabdominal sonographic evaluation of the canine prostate v.24 Cartee,R.E.;Rowles,T.
  8. J Am Vet Med Assoc v.184 Twodimensional, gray-scale ultrasonography for assessment of hepatic and oplenic neoplasia in the dog and cat Feeney,D.A.;Johnston,G.R.;hardy,R.M.
  9. AJR v.133 Accuracy of ultrasonography in diagnosis of hepatocellur disease Gosink,B.B.;Lemon,S.K.;Scheinble,W.;Lepoid,G.R.
  10. J In Vitro fert and Embryo Transfer Ultrasound scaning of the ovarian cycle Hackeler,B.J.
  11. Vet Res v.88 The application of some liver function tests to sheep dosed with carbon tetrachloride and hexachlorophene Harvey,D.G.;Hoe,C.M.
  12. Vet radiol & Ultrasound v.36 Ultrasonographic and biometer evaluation of sheep and cattle eyes Hussein,M.;E.L.Maghraby;Nyland,T.G.;Bellohorn,R.W.
  13. Vet radiol & Ultrasound v.36 Ultrasographic measurement of palmar metacarpal tendon and ligament structure in the horse Inmaculada Cuesta;Cristina,R.
  14. JAVMA v.195 Ultrasonography of noncardiac thorasic disease in small animal Jonathan,L.S.;Christopher,R.
  15. Radiology v.136 Ultrasound findings in gepatitis Kurtz,A.B.;Robin,C.S.;Cooper,H.S.;Nisenvaun,H.C.;Catherine Cole-Benglet, Medotl,J.; Goldberg,B.B.
  16. J Clin Ultrasound v.21 Chronic liver disease : comparison of ultrasound patterns with Laproscopy and Biopsy Martinez-Noguera A.;calonge,E.
  17. Vet Radioogy v.22 no.5 Grayscale ultrasonography of the canine abdomen Nyland,T.G.;Park,R.D.
  18. Vet Radiol v.24 Hepatic ultrasonography in the dog Nyland,T.G.;Park,R.D.
  19. Vet Radiol v.22 B-mode gray-scale ultrasound : Imaging artifacts and interpretation Park,R.D.;Nyland,T.T.;Lattimer,J.C.;Miller,C.W.;Lebel,J.L.
  20. Modern Veterinary Practice v.61 The diagnosis of liver disease in equine and food animals Pearson,E.G.;Craig,A.M.
  21. JAVMA v.191 Ultrasonographic diagnosis of portacaval shunts in young dogs Robert,H.W.;Linda,T.K.;Richard,D.P.;Jack,L.L.
  22. The priciples and practice of ultrasonography in obstetrics and gynecology(2nd ed.) Sanders,R.C.;Everette,Tames,A.
  23. Pathology of domestic animals(3rd ed.) Tubb,K.V.F.;Kennedy,P.C.;Palmer,N.
  24. Am J Vet Res v.29 Evaluation liver fomation tests and liver biopsy in experimental carbon tetratruction in the dog VanVleet,J.F.;Alberts,J.O.
  25. Veterinary pharmacholgy and Therapeutics(Fifth edition) The Iowa State University
  26. 한국임상수의 학회지 v.12 no.1 한우에서의 초음파 화상진단에 관한 연구 김명철;박관호
  27. 한국임상수의학회지 v.12 no.2 개에서 사염화탄소에 의해 유발된 간장병변의 초음파학적 관찰 성재기;윤정희;이영원;장동우;이희천
  28. 한국임상수의학회지 v.12 no.3 사염화탄소를 투여한 한국흑염소에 있어서 임상병리학적 연구 결과의 변동 이창우