• Title/Summary/Keyword: Factor V

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Calcium current on cryopreservation in mouse oocytes (동결 생쥐 난자에서의 calcium 전류)

  • Kang, Da-Won;Kim, Eun-Sim;Choe, Chang-Yong;Park, Jae-Yong;Han, Jae-Hee;Hong, Seong-Geun
    • Korean Journal of Veterinary Research
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    • v.42 no.1
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    • pp.35-43
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    • 2002
  • Cryopreservation is commonly used for an efficient utilization of semen, oocytes and embryos but has disadvantage in the survival, development of the post-thawed eggs. The high risk in the survival, development of eggs after thawing is thought to be caused by inappropriate internal regulation of $Ca^{2+}$ and/or formation of intracellular ice crystals. In this experiment, we tested whether the $Ca^{2+}$ current (iCa), a decisive factor to $Ca^{2+}$ entry, was altered in post-thawed oocytes by using whole cell voltage clamp technique. The quality and survival rates of the oocytes derived from both fresh and frozen groups were examined by morphology and FDA-test. Vitrified oocytes (VOs) were incubated for 4 hr after thawing and then donated to this experiment. Ethyleneglycol-ficoll-galactose (EFG) was used as a cryoprotectant for vitrification. The membrane potential was held at -80 mV and step depolarizations of 250 ms were applied from -50 mV to 50 mV in 10 mV increments. The survival rates showed a higher in VOs vitrified with EFG containing $Ca^{2+}$ than in VOs vitrified with EFG under the $Ca^{2+}$-free condition (82.0% vs 14%). In group with/without $Ca^{2+}$, the survival rates were significantly (P<0.01) difference. In the fresh metaphase II oocytes (FOs), current-voltage (I-V) relationship showed that iCa began to activate at -40 mV and reached its maximum at -10 mV. With same voltage pulses, inward currents were elicited in VOs. I-V relationships observed in VOs were similar to those in FOs. Time constants of activation and inactivation of the inward current shown in VOs were not different to those in FOs. This accordance in I-V relations and time constants in FOs with those in VOs indicates that the inward currents in FOs are unaltered by vitrification and thawing. Therefore, vitrification with EFG does not play as a factor to deteriorate $Ca^{2+}$ entry across the membrane of the oocytes.

Control of Platelet Rolling and Adhesion

  • Moskowitz, Samuel E.
    • 제어로봇시스템학회:학술대회논문집
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    • 2002.10a
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    • pp.77.1-77
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    • 2002
  • Platelets arrest bleeding and repair damaged blood vessels. The purpose of this paper is to formulate a mathematical model for the control of platelet adhesion within the vasculature consistent with experimental findings, particularly those of Frenette, Ruggeri , Savage, Yuan, Lawrence and Springer. In addition to providing some, albeit rudimentary, insight into the behavior of platelets, a numerical simulation of this theoretical model may be useful in a systematic study of pathological cases. Glycoprotein receptor complex (GPIb/V/IX), found on the platelet surface membrane, binds to the adhesive protein and ligand von Willebrand factor (vWf), located within the sub-endothelium. The binding...

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FPGA Implementation of Underlying Field Arithmetic Processor for Elliptic Curve Cryptosystems (타원곡선 암호시스템을 위한 기저체 연산기의 FPGA 구현)

  • 조성제;권용진
    • Proceedings of the IEEK Conference
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    • 2000.11b
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    • pp.148-151
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    • 2000
  • In recent years, security is essential factor of our safe network community. Therefore, data encryption/ decryption technology is improving more and more. Elliptic Curve Cryptosystem proposed by N. Koblitz and V. Miller independently in 1985, require fewer bits lot the same security, there is a net reduction in cost, size, and time. In this paper, we design high speed underlying field arithmetic processor for elliptic curve cryptosystem. The targeting device is VIRTEX V1000FG680 and verified by Xilinx simulator.

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Schur Multipliers and Cohomology of Finite Groups

  • LEE, YEANG-SOO
    • Honam Mathematical Journal
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    • v.1 no.1
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    • pp.43-49
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    • 1979
  • G를 유한군으로, C를 모든 복소수체로 가정하고, V를 C상에서의 유한차원 벡터공간이라 하자. V상에서의 G의 사영적 표시는, X, $y{\epsilon}G$이고 ${\alpha}:\;G{\times}G{\rightarrow}C$를 Facto set이라 할 때 $T(x)T(y)=T(xy){\alpha}(x,y)$이 되는 함수 $T=\;G{\rightarrow}GL(V)$를 말한다. 본 논문의 목적은 군에 대한 Extension theory를 사용해서, G상의 factor set들의 동치류들은 G의 Second Cohomology group과 동형이라는 것을 증명하는 것이다.

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A Study on V.M.D(Visual Merchandising Design) Environment of Mobile Telecommunication Company Store (이동통신 회사 매장의 V.M.D(Visual Merchandising Design) 환경에 관한 연구)

  • Kim, Jong Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.4
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    • pp.1589-1594
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    • 2013
  • V.M.D(Visual Merchandising Design) covers every space, environment, and visually stimulating factor. This includes not only the architectural appearance but interior, graphic sign boards, window display, layout, store appliances, lighting, and even the looks and service attitude that sales employees have and show to customers. V.M.D aims to display merchandise in multiple ways; to heighten brand images; to steadily lure many customers to the store. One of the characteristics that V.M.D has is, that this abandons the previous design concept which solely puts stress on luxurious interior-focused display; that this displays merchandise in a rational and systemic way and induces customers to buy products. In this regard, the objective of this study is to study brand perception and effect of V.M.D displayed in the stores, on customers, and thereby to present the concepts of V.M.D, suitable for display in the stores, which can be used continuously in the future.

Seasonal and Spatial Variation of Pathogenic Vibrio Species Isolated from Seawater and Shellfish off the Gyeongnam Coast of Korea in 2013-2016 (2013-2016년 경남 연안 해수 및 패류에서 병원성 비브리오균의 계절적 및 지역적 변동)

  • Park, Kunbawui;Mok, Jong Soo;Kwon, Ji Young;Ryu, A Ra;Shim, Kil Bo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.1
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    • pp.27-34
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    • 2019
  • The seasonal and spatial variation of pathogenic Vibrio species, such as V. parahaemolyticus, V. vulnificus, V. alginolyticus, and V. cholerae were investigated in seawater and in bivalves off the Gyeongnam coast of Korea, which is an important area for shellfish production, during the period 2013-2016. V. parahaemolyticus, V. vulnificus, V. alginolyticus, and V. cholerae were detected in 12.1%, 5.2%, 15.4%, and 0.9% of seawater samples, respectively. V. parahaemolyticus, V. vulnificus, V. alginolyticus, and V. cholera were detected in 21.9%, 7.1%, 12.2%, and 0.0% of shellfish samples, respectively. The Vibrio spp. in seawater and bivalve samples were detected at high levels during the summer to early autumn; however, the levels were low during the winter. Therefore, their occurrence was seasonally dependent and correlated with high water temperature, which is also the biggest factor contributing to foodborne outbreaks associated with Vibrio. Relatively high detection rates of the strains were also found in the sea area that was continually exposed to inland wastewater. Our findings show that continuous monitoring is needed to reveal the patterns of occurrence of these pathogens from marine samples collected off the Korean coast, to reduce seafood-borne outbreaks caused by Vibrio.

SNU 1.5 MV Van de Graaff Accelerator (V) -on the Operation of the High Voltage Stabilization System- (NU 1.5MV 반데그라프 가속기 (V) -고전압 안정화 계통의 동작-)

  • Bae, Y.D.;Bak, H.I.;Chung, K.H.;Woo, H.J.;Choi, B.H.
    • Nuclear Engineering and Technology
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    • v.19 no.2
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    • pp.115-121
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    • 1987
  • A high voltage stabilization system for the SNU 1.5MV Tandem Van do Graaff accelerator was set up and its operational characteristics were examined and optimized. The optimum parameters of beam transport system were experimentally determined, and under the proper condition the accelerated proton beam current of 350nA was obtained at the target chamber. Without the high voltage stabilization the observed magnitude of voltage fluctuation was $\Delta$V/ V=5.2$\times$10$^{-3}$ without ion beam and 7.2$\times$10$^{-3}$ with ion beam, respectively, and its apparent ripple frequency for voltage fluctuations was about 3Hz or less. Through the optimized operation of the high voltage stabilization system, the terminal voltage fluctuation was reduced to $\Delta$V/V=2.45$\times$10$^{-4}$ and the energy stability with $\Delta$E/E=2.44$\times$10$^{-4}$ was steadily maintained at the 247.3kV terminal voltage, and the stabilization factor was deduced to be 29.4.

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Analysis of Coagulation Factor Activity of Normal Adults with APTT Limit Range (APTT에서 경계치에 속한 정상 성인의 혈액응고인자 활성도 분석)

  • Kwon, Eui-Hoon;Koo, Bon-Kyung;Bang, Sung-Hwan;Kim, Hee-Jin;Cho, Young-Kuk
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.4
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    • pp.237-242
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    • 2015
  • The coagulation factor activity compared two groups of the lower 10% (29.1~30.9 sec) and the upper 10% (38.0~41.9 sec) of the normal reference range of aPTT. The aim of this study was to investigate the influence of sex, age, and ABO blood type on coagulation factor activity. There was significant difference in the activity of the coagulation factor assay based on age. The VIII (p<0.0001) and IX (p=0.0050) in the lower group of samples from those over sixty years of age is higher than from those under sixty. In contrast, XII (p=0.0285) for samples over sixty was lower than for samples under sixty. While in the upper group V (p=0.0219), VIII (p=0.0005), and IX (p=0.0014) for samples from the over sixty group was higher than those under sixty. In the case of activity of coagulation factor between O and non-O blood type, VIII (p<0.001) activity of the non-O blood type was higher than that of the O blood type in the both groups. The XII (p=0.016) activity of non-O blood type was lower than that of O blood type in the upper group. According to the multiple logistic regression analysis, when other variables are under the same conditions between lower and upper groups, there is a strong possibility for the lower group when activity of V (p=0.001), VIII (p<0.001), X (p<0.001) and XII (p<0.001) is increased. Furthermore, there is also a strong possibility of upper group when activity of II (p=0.004) and IX (p=0.012) is increased. However, no significant difference in between sex, age and XI was observed.

The Problem of Disjunctive Causal Factors: In Defense of the Theory of Probabilistic Causation

  • Kim, Joon-Sung
    • Korean Journal of Logic
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    • v.5 no.2
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    • pp.115-131
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    • 2002
  • The problem of disjunctive causal factors is generalized as follows. Suppose that there are no factors of the kind considered so far that need to be held fixed in background contexts. Nevertheless, it is still possible that within the background contexts, each disjunct of a disjunctive causal factor X v W confers a different probability on an effect factor in Question. So a problem arises of how we identify a single causally significant probability of the effect factor in the presence of the disjunctive causal factor, assuming that each disjunct of the disjunctive causal factor confers a different probability on the effect factor. In this paper, I first introduce an experiment in which disjunctive causal factors seem to pose a problem for the theory of probabilistic causation. Second, I show how Eells' solution to the problem of disjunctive causal factors meets the problem that arises in the experiment. Third, I examine Hitchcock's arguments against Eells' solution, arguing that Hitchcock misconstrues Eells' solution, and disregards the feature of the theory of probabilistic causation such that a factor is a causal factor for another factor relative to a population P of a population type Q.

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Efficiency factor of high calcium Class F fly ash in concrete

  • Sata, V.;Khammathit, P.;Chindaprasirt, P.
    • Computers and Concrete
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    • v.8 no.5
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    • pp.583-595
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    • 2011
  • This paper studied the cement efficiency factor (k factor) of high calcium Class F fly ash. This k factor represents a unit of fly ash with efficiency equivalent to k unit of cement. The high calcium Class F fly ash was used to replace cement in concrete. The modified Bolomey's law with linear relationship was used for the analysis of the result of compressive strength, cement to water ratio (c/w) and fly ash to water ratio (f/w) by using the multi-linear regression to determine the k factor and other constants in the equations. The results of analysis were compared with the results from other researcher and showed that the k factor of high calcium Class F fly ash depends on the fineness of fly ash, replacement level and curing age. While the amount of CaO content in Class F fly ash not evident. Furthermore, necessary criteria and variables for the determination of the k factor including the use of the k factor in concrete mix design containing fly ash were proposed.