• Title/Summary/Keyword: ASCT

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A Case of Drug-Induced Hepatitis due to Bortezomib in Multiple Myeloma

  • Kim, Young-Woon;Kim, Ka-Young;Lee, Su-Hyun;Chung, Yoon-Yung;Yahng, Seung-Ah;Lee, Sung-Eun;Park, Gyeong-Sin;Min, Chang-Ki
    • IMMUNE NETWORK
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    • v.12 no.3
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    • pp.126-128
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    • 2012
  • We report on a case of severe hepatotoxicity in a 52-year-old male with multiple myeloma (MM) who had received bortezomib therapy. At patient presentation, liver enzymes were normal, but started to markedly increase 3 days after the patient's second dose of bortezomib was administered, when free kappa light chains were noticeably reduced in the serum. After discontinuation of bortezomib, liver enzymes recovered gradually to baseline. Then, the patient was started on a thalidomide-containing regimen, which he was able to tolerate well. The patient achieved complete remission prior to autologous stem cell transplantation (ASCT). The patient underwent ASCT without occurrence of further liver toxicity.

Fabrication of Disordered Subwavelength Structures on Curved Surfaces by Using a Thermal Dewetting Process

  • Lee, Jong Heon;Song, Young Min
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.172-177
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    • 2015
  • We present disordered moth eye structures on curved surfaces fabricated by dry etching of thermally dewetted metal nanoparticles. This lithography-free fabrication allows the formation of subwavelength scale nanostructures on the strongly inclined surfaces such as ball lens as well as on the microlens arrays with low curvature. In particular, we found that the size and average distance of nanostructures are closely related to the inclined angle of the surface. Experimental results on oblique angle deposition of metal thin films followed by thermal dewetting also support these effects.

Probing the Molecular Orientation of ZnPc on AZO Using Soft X-ray Spectroscopies for Organic Photovoltaic Applications

  • Jung, Yunwoo;Lee, Nalae;Kim, Jonghoon;Im, Yeong Ji;Cho, Sang Wan
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.151-155
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    • 2015
  • The interfacial electronic structure between zinc phthalocyanine (ZnPc) and aluminumdoped zinc oxide (AZO) substrates has been evaluated by ultraviolet photoemission spectroscopy and angle-dependent x-ray absorption spectroscopy to understanding the molecular orientation of a ZnPc layer on the performance of small molecule organic photovoltaics (OPVs). We find that the ZnPc tilt angle improves the ${\pi}-{\pi}$ interaction on the AZO substrate, thus leading to an improved short-circuit current in OPVs based on phthalocyanine. Furthermore, the molecular orientation-dependent energy level alignment has been analyzed in detail using ultraviolet photoemission spectroscopy. We also obtained complete energy level diagrams of ZnPc/AZO and ZnPc/indium thin oxide.

Failure Analysis of Filaments of Quadrupole Mass Spectrometer for Plasma Process Monitoring

  • Ha, Sung Yong;Kim, Dong Hoon;Joo, Junghoon
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.142-150
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    • 2015
  • A failure analysis of tungsten filaments used in quadrupole mass spectrometer for plasma process monitoring was carried by using SEM and EDS. Failed at high temperature, filaments showed two kinds of failure modes. The one is that diameter of filament became thinner gradually and finally snapped. The other is that filament abruptly snapped almost at a right angle. The EDS analysis showed Fe and C, including W and Fe, on the surface of failed filament. when failed filaments were treated with plasma in mixture of Ar and $CF_4$, the amount of Fe and C decreased. The failure analysis of filament showed that the cause of filament failure is thermal evaporation and grain growth of tungsten at high temperature.

Linear Ion Beam Applications for Roll-to-Roll Metal Thin Film Coatings on PET Substrates

  • Lee, Seunghun;Kim, Do-Geun
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.162-166
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    • 2015
  • Linear ion beams have been introduced for the ion beam treatments of flexible substrates in roll-to-roll web coating systems. Anode layer linear ion sources (300 mm width) were used to make the linear ion beams. Oxygen ion beams having an ion energy from 200 eV to 800 eV used for the adhesion improvement of Cu thin films on PET substrates. The Cu thin films deposited by a conventional magnetron sputtering on the oxygen ion beam treated PET substrates showed Class 5 adhesion defined by ASTM D3359-97 (tape test). Argon ion beams with 1~3 keV used for the ion beam sputtering deposition process, which aims to control the initial layer before the magnetron sputtering deposition. When the discharge power of the linear ion source is 1.2 kW, static deposition rate of Cu and Ni were 7.4 and $3.5{\AA}/sec$, respectively.

Diamagnetic Shift of a InGaP-AlInGaP Semiconductor Single Quantum Well under Pulsed-magnetic Fields

  • Choi, B.K.;Kim, Yongmin;Song, J.D.
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.156-161
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    • 2015
  • Application of magnetic fields is important to characterize the carrier dynamics in semiconductor quantum structures. We performed photoluminescence (PL) measurements from an InGaP-AlInGaP single quantum well under pulsed magnetic fields to 50 T. The zero field interband PL transition energy matches well with the self-consistent Poisson-$Schr{\ddot{o}}dinger$ equation. We attempted to analyze the dimensionality of the quantum well by using the diamagnetic shift of the magnetoexciton. The real quantum well has finite thickness that causes the quasi-two-dimensional behavior of the exciton diamagnetic shift. The PL intensity diminishes with increasing magnetic field because of the exciton motion in the presence of magnetic field.

Interband Transition and Confinement of Charge Carriers in CdS and CdS/CdSe Quantum Dots

  • Man, Minh Tan;Lee, Hong Seok
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.167-171
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    • 2015
  • Quantum-confined nanostructures open up additional perspectives in engineering materials with different electronic and optical properties. We have fabricated unique cation-exchanged CdS and CdS/CdSe quantum dots and measured their first four exciton transitions. We demonstrate that the relationship between electronic transitions and charge-carrier distributions is generalized for a broad range of core-shell nanostructures. These nanostructures can be used to further improve the performance in the fields of bio-imaging, light-emitting devices, photovoltaics, and quantum computing.

Vanadium Oxide Microbolometer Using ZnO Sandwich Layer

  • Han, Myung-Soo;Kim, Dae Hyeon;Ko, Hang Ju;Kim, Heetae
    • Applied Science and Convergence Technology
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    • v.24 no.5
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    • pp.178-183
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    • 2015
  • Optical, electrical and structural properties of VOx/ZnO/VOx thin film are studied. The VOx/ZnO/VOx multilayer is deposited by using a radio frequency (RF) sputtering system. The VOx/ZnO/VOx thin film shows the high temperature coefficient of resistance (TCR) of $-3.12%/^{\circ}C$ and the low sheet resistance of about 80 $k{\Omega}/sq$ at room temperature. The responsivity and detectivity of the bolometer are measured as a function of modulation frequency.

Direct Growth of Graphene on Insulating Substrate by Laminated (Au/Ni) Catalyst Layer

  • Ko, Yong Hun;Kim, Yooseok;Jung, Daesung;Park, Seung Ho;Kim, Ji Sun;Shim, Jini;Yun, Hyeju;Song, Wooseok;Park, Chong-Yun
    • Applied Science and Convergence Technology
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    • v.24 no.4
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    • pp.117-124
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    • 2015
  • A direct growth method of graphene on insulating substrate without catalyst etching and transfer process was developed using Au/Ni/a-C catalyst system. During the growth process, behavior of the Au/Ni catalyst was investigated using EDX, XPS, SEM, and Raman spectroscopy. The Au/Ni catalyst layer was evaporated during growth process of graphene. The graphene film was composed mono-layer flakes. The transmittance of the graphene film was ~80.6%.

Quantitative Evaluation on Photocatalytic Activity of Anatase TiO2 Nanocrystals in Aqueous Solution

  • Jeon, Byungwook;Kim, Yu Kwon
    • Applied Science and Convergence Technology
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    • v.24 no.4
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    • pp.96-101
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    • 2015
  • Quantitative evaluation of photocatalytic activity of oxide nanoparticles in aqueous solution is quite challenging in that the kinetic reaction rate is determined by a complicated interplay among various limiting factors such as light scattering and absorption, diffusion and adsorption of reactants in condensed liquid phase, photoexcited charge separation and recombination rate, and the exact nature of active sites determined by detailed morphology and crystallinity of nanocrystals. Here, we present our simple experimental results showing that the kinetic regime of a typical photocatalytic degradation experiment over UV-irradiated $TiO_2$ nanoparticles in aqueous solution is in that dominated by the photoactivity of $TiO_2$ and its concentration. This result lays a firm ground of using the measured kinetic reaction rate in evaluating photocatalytic efficiency of oxide nanocrystals under evaluation.