• Journal of Oriental Neuropsychiatry
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• v.19 no.2
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• pp.223-230
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• 2008

소합향원 (蘇合香元) 가감방(加減方) 정유향기의 진통효과가 투여방법에 따라 어떤 차이가 있는지를 비교, 검토함으로서 본 약재의 새로운 적용방법을 탐색해 보고자 한다. 방법 : 가감소합향원에서 추출한 정유향기를 실험동물을 대상으로 7일간 경구 (50mg/kg, 100mg/kg), 흡입 (매일 3시간씩 1일 2회), 또는 피부도찰 (10mg) 방법으로 투여하여 페닐퀴논-유도 writhing test, 아세트산-유도 writhing test 및 hot-plate test를 실시하였다. 결과 : 가감소합향원 정유향기는 페닐퀴논-유도 writhing test에서는 피부도찰이 가장 효과적 이었으며 그 효과는 양성 대조약물인 아세트아미노펜 보다 약간 더 우수하였다 (p<0.05). 아세트산-유도 writhing test에서도 피부도찰법이 가장 좋은 효과를 나타내었으며 양성대조 약물인 아미노피린보다는 좀 더 좋은 효과를 보여주었다 (p<0.05). 그러나 hot-plate test에서는 경구투여가 가장 좋은 진통효과를 나타내었는데 고용량 (100mg/kg)에서는 양성 대조약물인 아세트아미노펜보다 유의적으로 더 효과적이었으나 저용량 (50mg/kg )에서는 이보다 다소 약하였다. 이상의 연구결과, 가감소합향원의 정유향기는 피부도찰시에는 비특이적 화학자극제인 페닐퀴논이나 아세트산에 의한 통증의 완화에 보다 효과적이며, 경구투여시에는 중추신경계에 영향을 미치는 hot plate에 의한 열자극성 통증에 더 유효함을 의미한다. 결론 : 가감소합향원의 정유향기액은 향기흡입보다는 피부흡수나 경구투여방법으로 진통의 목적으로 응용될 수 있을 것으로 사료된다.

• Journal of Life Science
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• v.23 no.7
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• pp.933-940
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• 2013

The aim of this work was to determine the chemical composition of essential oil from aerial partsof Mentha arvensis L. f. piperascens (MAO) and to evaluate the effect of its fragrant chemicals on electroencephalographic (EEG) activity of human brain. The MAO was obtained by supercritical $CO_2$ extraction. The maximum yield was 2.38% at conditions of $70^{\circ}C$ and 200 bar. There were 32 volatile chemicals with 6 alcohols (67.11%), 13 hydrocarbons (17.05%), 9 esters (11.50%), 2 ketones (7.16%), 1 oxide (2.77%), and 1 aldehyde (0.56%). The major components were (Z,Z,Z)-9,12,15-octadecatrien-1-ol (50.06%), 2-hydroxy-4-methoxyacetophenone (7.50%), and 3,4-dihydro-8-hydroxy-3-methyl-1H-2-benzopyran-1-one (6.60%). Results of the EEG study showed that inhalation of MAO significantly changed the EEG power spectrum values of relative gamma, relative fast alpha, and spectral edge frequency 90%. During the inhalation of MAO, the value of relative fast alpha was significantly increased (p<0.05). On the other hand, the values of gamma and the spectral edge frequency 90% were significantly decreased (p<0.05). The present study suggests that fragrant chemicals of essential oil of M. arvensis reduce the level of mental stress and that they could be used in the treatment of psychophysiological disorders.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.16 no.3
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• pp.300-306
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• 2009

Purpose: This study was done to investigate differences between lavender abdominal massage and inhalation on dysmenorrhea, menstrual pain, anxiety, and depression. Methods: This study used a non equivalent quasi-experimental design. Lavender essential oil and almond oil were used in massage and a lavender necklace and artificial perfume necklace in inhalation for female college students. Frequencies, percentages, Chi-square, Fisher's exact test and t-test with the SPSS/WIN 12.0 program were used to analyze the data. Results: Dysmenorrhea was significantly higher inhalation for placebo treatment compared to lavender inhalation (p< .001). There was not significant difference between lavender abdominal massage and inhalation. Conclusion: Lavender abdominal massage and inhalation could be effective methods to reduce dysmenorrhea. However, before lavender abdominal massage and inhalation can be considered as intervention, it is more needed to study of menstrual pain, anxiety and depression.

• The Journal of the Convergence on Culture Technology
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• v.4 no.2
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• pp.171-178
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• 2018

The study was done to analyze the effects of aroma inhalation method on preoperative anxiety of upper and lower surgical patients. The research design was a nonequivalent control group non-synchronized design. The subjects were a total 60 patients of each group 30 patients that were operated on under general anesthesia for upper and lower limbs surgery. The tool of the Amsterdam preoperative anxiety information scale(APAIS), systolic and diastolic blood pressure, and pulse rate levels was measured the day before surgery. The data were analyzed by the $x^2$ test Fisher's exact test, paird t-test, and the independent t-test using SPSS 20.0. Study result indicated that Lavender aroma therapy had the effect on reduction of anxiety before surgery and reduction of blood pressure, and pulse rate levels. Therefore, the study result could be used as a scientifical data that can be applied to the nursing interventions that use the aroma inhalation method and contributing to development of the holistic nursing care.

• Korean Journal of Adult Nursing
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• v.16 no.1
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• pp.135-145
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nausea vomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city after receiving more than two Cisplatin combination chemotherapy treatments. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, $x^2$-test, t-test, Repeated Measures ANOVA. Result: 1) The degree of nausea and vomiting in the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2) The degree of anorexia in the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nausea vomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nausea vomiting and anorexia who are receiving chemotherapy.

• Korean Journal of Hospice Care
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• v.4 no.2
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• pp.42-51
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• 2004

Purpose: The purpose of this study was to examine the effects of aroma oil inhalation using peppermint and bergamot on nauseaㆍvomiting and anorexia in cancer patients receiving chemotherapy. Method: Study subjects were 30 patients who had experienced nausea and vomiting when they had been hospitalized in K university hospital located in D city to receiving more than two Cisplatin combination chemotherapy. Among them 15 patients were in the experimental group doing aroma oil inhalation and the other 15 patients were in the control group without aroma oil inhalation. The data were collected from February 1, 2002 to May 17, 2002. The data were collected from February 1, 2000 to May 17, 2002. The data were analyzed with SPSS WIN 10.0 program using frequency, percentage, X2-test, t-test, Repeated Measures ANOVA. Result: 1)The degree of nauseaㆍvomiting on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. 2)The degree of anorexia on the experimental group with aroma oil inhalation using peppermint and bergamot were significantly lower than that of the control group. Conclusion: aroma oil inhalation was effective for relieving patients' nauseaㆍvomiting and anorexia receiving chemotherapy. Therefore, it is proposed that aroma oil inhalation should be applied as a supportive nursing arbitration method to relieve patients' nauseaㆍvomiting and anorexia who are receiving chemotherapy.

• Journal of Life Science
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• v.26 no.3
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• pp.346-352
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• 2016

Aroma inhalation therapy has traditionally been used not only in alternative medicinal treatment but also in psychotherapy. In the first stage of the study, the in silico molecular binding affinity of the major ingredients of Smart-Wave (SW) on the active site of the odorant-binding protein (OBP) was compared with that of citrate anions. The binding affinity of the chemical mixture formula of the major ingredients of SW on the OBP was relatively higher than that of citrate anions. In addition, nasal inhalation of SW had a positive effect upon changes in brain waves. Eighteen healthy volunteers participated in the experiment. The study consisted of measurements of the brain’s meditation level recordings in the pre- and post-SW inhalation periods as compared with negative (EV) and positive (HB) control groups. After SW inhalation, all the subjects stated that they felt “fresher” and that the SW trial group had significantly changed the brain’s meditation in a positive way. SW inhalation also converted EV-induced unstable brain meditation wave patterns into more stable patterns. Collectively, the results of this empirical study strongly suggest that the SW mixture activates the OBP and controls the mental state by regulating brain waves. The results provide scientific evidence that the SW formula has potential as an effective mental-stress controller.

• Korean Journal of Adult Nursing
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• v.22 no.2
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• pp.153-160
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• 2010

Purpose: The purpose of this study was to investigate the effects of aromatherapy on stress, fatigue, mood, and vital signs of the nurses in the operating rooms. Methods: The data were collected from September 2007 to February 2008 in the operating room at K hospital located in Seoul, Korea. A total of 48 nurses were recruited. Among them, 25 nurses were randomly assigned to an experimental group and 23 were assigned to a control group. Experimental group was provided with aroma inhalation by necklace which had essential oil mixture of 0.2 cc. For aroma inhalation, Lavender, Zeranium and Mazoram were mixed in ratio of 5:3:2. In order to test the effectiveness of aroma inhalation, the pretest and posttest results for stress, fatigue, mood, and vital signs were compared between the experimental group and the control group. The data were analyzed by unpaired t-test and ANCOVA using the SPSS/WIN 15.0 program. Results: There were statistically significant decreases in the stress and fatigue scores, and increase in the mood scores and showed significant relaxation in the vital signs after the aroma inhalation. Conclusion: The aromatherapy had the positive effects on stress, fatigue, mood, and vital signs.

• Korean Journal of Adult Nursing
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• v.17 no.3
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• pp.358-367
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• 2005

Purpose: This study was to test some effects on pain, depression and ego integrity of the elderly by adapting group reminiscence therapy with mugwort fragrance to the elderly with chronic pain. Method: The research was executed from April 2001 through September 2001, and research participants were male and female olderly people randomly assigned from 3 environmentally similar day care centers. They were divided into experimental group A and B, and a control group; The control group was divided into a daily care group and a regularly visiting group, and the experimental group A was for group reminiscence therapy with mugwort fragrance inhalation and the group B for group reminiscence therapy. Result: The group reminiscence therapy with mugwort fragrance inhalation showed significant effects on decrease of pain and depression, and improvement of ego integrity, and for 2 weeks after the treatment proved its continuous effect. Conclusion: The result above explains the fact the mugwort fragrance stimulates reminiscence and shows curing effects. In further researches, it is necessary to adapt various health problems of the elderly, not only to the aged with chonic pain.

• Women's Health Nursing
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• v.9 no.1
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• pp.70-79
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• 2003

The purpose of this study was to investigate the effects of Aromatherapy, inhalhtion method using Clarysage essential oil on stress in middle-age women. The study design was a one-group pretest-posttest design. The subject were 44 middle-age women with stress in inhalation method of Clarysage essential oil was 2 drops of oil on tissue at 10, 14, 18, before bed for 2 weeks. The study was carried out from August 1 to September 20, 2002. The scale used in the study was the stress scale of Park, Sun Young(1999). The study data was analyzed by frepuency, percent age and t-test using SPSS Win 10.0 program. Result were as follows : 1. The score of physical stress scale was significantly decresed after use of inhalation of Clarysage essential oil. 2. The score of psychological stress scale was significantly decresed after use of inhalation of Clarysage essential oil. In conclusion, the results of this study suggest that inlalation method using Clarysage essential oil is positively supported in stress reduction in middle-aged women.