• Proceedings of the Korean Society for Bio-Environment Control Conference
• /
• 2003.04a
• /
• pp.132-134
• /
• 2003

독특한 향기와 향미를 지닌 식물성 천연 정유는 향수, 향신료 및 의약품 등 다양한 산업분야에서 응용되고 있다. 특히, 정유를 이용한 면역성 증가(Buchbauer, 1991), 신경계 안정효과, 항암효과(Zheng, 1993), 노화억제 및 항균력(Sowthwell,1996) 등의 약리적 특성이 보고됨에 따라 천연정유를 산업적으로 응용하게 되었고, 더욱 증가하게 되었다 (Lawless, 1995). 식품 및 화장품업계에서 천연향신료, 천연방부제 및 감미료가 갖는 항균작용과 항산화 활성에 관한 연구에 관심이 집중되면서, 식물성 천연정유는 본래의 향미 기능 외에 부가가치가 더욱 상승되고 있다(Deans and Waterman, 1993). (중략)

• YAKHAK HOEJI
• /
• v.14 no.1_2
• /
• pp.21-27
• /
• 1970

Isoimperatorin and Oxypeucedanin isolated from root of Angelica Koreana Max. (Umbelliferae) that is used as "Kang-Whal" a botanical drug, in Korea, Show following general pharmacologic activities. The treatment with Oxypeucedanin on the exercised duodenum of the rabbit increased the motility of it while isoimperatorin shows little effects. But on the exercised heart of the frogs, both components depressed its contractility. Whereas Oxypeucedanin depressed both blood pressure of the carotied artery and respiration of the rabbit, Isoimperatorin tends to increase blood pressure, respiration and the tonus of the muscle of the earth worm. Oxypeucedanin did not affect the tonus of the muscles of the earth worm, but depressed the uterus contraction of the rabbit, which was, on the contrary, increased by Isoimperatorin.

• Korean Journal of Pharmacognosy
• /
• v.11 no.2
• /
• pp.57-60
• /
• 1980

Water fractions prepared from Plantaginis Semen and Plantaginis Folium exhibited both significant liver-protective activities against $CCl_4$ intoxication. Aucubin, an iridoid glycoside. isolated from both leaves and seeds of Plantago asiatica(Plantaginaceae) also showed potent liver protective activities against the animal model of hepatitis induced by $CCl_4$ intoxication.

• Journal of Plant Biotechnology
• /
• v.37 no.1
• /
• pp.47-56
• /
• 2010

Sea buckthorn (Hippophae rhamnoides L.) is deciduous shrubs in the genus Hippophae, mainly cultivated in Europe and Asia. Sea buckthorn berries have a high vitamin C, vitamin E, carotenoids, carbohydrates, protein, organic acids, dietary minerals, triterpenoids, polyphenolic acids and amino acids. Extracts of sea buckthorn berries have anti- obesity, anti-oxidantive, anti-microbial, anti-ulcerogenic, anti-diabetic and nutritional effects. Sea buckthorn used as a traditional medicine for the treatment of cough, aid digestion, invigorate blood circulation and alleviate pain. Extracts of sea buckthorn branches and leaves was administered to humans and animals to treat gastrointestinal distress in Mongolia. This paper briefly reviews the most relevant experimental data on the pharmacological effects and isolated component of sea buckthorn. And, we also describe the importance of sea buckthorn as the environmental-friendly crops.

• Korean Journal of Veterinary Research
• /
• v.2 no.2
• /
• pp.29-31
• /
• 1962

Although Lycaconitine, one of the alkaloids of Radix Jingyu, had been identified in 1884, its use in practice has not been known probably because of our limited knowledge on pharmacologic actions of the drug. Recently repellent efficacy of Lycaconitine against Korean cattle ticks and goat ticks was demonstrated. Obviously, there in a need to investigate toxicologic aspects of Lycaconitine before its widespread use for the control of animal ticks can be attempted. As will be reported in this paper, Lycaconitine Shows a wide margin of safety in the concentration applied as cattle or goat tick repellent.

• Journal of Pharmaceutical Investigation
• /
• v.6 no.3
• /
• pp.70-76
• /
• 1976

Pharmacological studies on the water extracts of Sambbcus latipnna var. coreana have confirmed that there are: 1) Remarkable sedative actions in preteated mice with C.N.B (caffeine and sodium benzoate) by the administration of intraperitoneal injection. 2) Antihypertensive actions in rabbits intraperitoneally injected with the extract, and as antihypertensive components, rutin, and crystal A (m.p. $250{\sim}254^{\circ}$, Liberman-Buchard's reaction, positive) were isolated from Sambucus latipinna var. coreana. 3) Marked diuretic actions in mice intramuscular injection with the dose of 600mg/kg.

• Proceedings of the Korean Society of Fisheries Technology Conference
• /
• 2000.05a
• /
• pp.80-81
• /
• 2000

미역(Sea mustard, Undaria pinnatifida)은 옛부터 임산부나 환자들에게 영양식으로 공급되어 온 우리나라의 전형적인 해조류이다. 미역에는 Ca, Fe, I등과 같은 무기질이 풍부할 뿐만 아니라(립원, 1975; 전중) 미역의 세포막 구성성분으로 다량 존재하는 알긴산은 콜레스테롤 배출작용, 중금속(Cd), 방사능 물질(Sr)의 체내 흡수 억제 및 배출 작용과 정장작용 등이 있는 것으로 보고되고 있으며(태전, 1987; Suzuki et al., 1993), 비만을 방지하기 위한 dietary fiber 식품으로서 각광을 받고 있다(홍소, 1984). 그리고 미역과 같은 갈조류에 존재하는 fucoidan은 항암효과가 있는 것으로 알려져 있다(Yamamoto and Maruyama, 1983; Sakagami, 1983). 이처럼 미역은 열량보다는 건강 및 약리적으로 우수한 식품임에도 불구하고 계속적인 내수소비 및 대일 수출감소로 재고가 매년 누적됨에 따라 미역 양식산업의 채산성은 날로 악화되어 가고 있는 실정이다. (중략)

• YAKHAK HOEJI
• /
• v.45 no.3
• /
• pp.251-257
• /
• 2001

The study was carried out to evaluate the preliminary toxicity and general pharmacology of KML-IIU, a purified pectin from Korean Mistletoe (Viscum album coloratum). KML-IIU was administered intravenously to ICR mice and Spargue-Dawley rats to investigate the acute toxicity. LD50 values in mice and rats were above 30 $\mu$g/kg. KML-IIU had no effects on the general behaviors, acetic acid induced writhing syndrome, pentobarbial induced sleeping time, pentylenetetrazole induced convulsion and the change of body temperature. In addition, KML-IIU did not show any effects on digestive system and blood coagulation system.

• YAKHAK HOEJI
• /
• v.7 no.4
• /
• pp.86-91
• /
• 1963

Crystal A and B were isolated from L. pseudo-leave Nakai and their pharmacological action was observed. Crystal A, in dose of 5 * $10^{-4}$ - 5 * $10^{-5}g/ml$, stimulated excised frog heat but at 2.5 * $10^{-6}$ - 0.5 * $10^{-5}g/ml$ of crystal B, depressant effect was observed. Mild stimulation of rhythmicity of exercised rabbit intestine was produced by 1 * $10^{-4}$ g/ml of crystal A and 2 * $10^{-4}g/ml$ of crystal B. Marked depression of tone was produced by 2 * $10^{-4}g/ml$ of crystal A, antagonizing by pilocarpine. Crystal B(4 * $10^{-4}gm/l)produced$ mild stimulation, followed by depression of tone. No curare-like action on excised frog abdominal muscle was elicited with both substances.

• Korean Journal of Pharmacognosy
• /
• v.1 no.1
• /
• pp.25-32
• /
• 1970

Decursin, decursinol and nodakenin which were isolated from the root of Angelica gigas $N_{AKAI}$ (Umbelliferae) that is used as a botanical drug Dang-Gui (當歸) in Korea show following general pharmacologic activities. Decursin and decursinol increased the motility of the excised duodenum of the rabbit, but nodakenin did not. All of these three compounds depressed the heart contraction of the frog and blood pressure of the carotid artery and respiration of the rabbit. Decursin increased uterus contraction of the rabbit, but decursinol depressed it. And the tonus of the muscle of the earth worm was increased by decursinol, but was decreased by decursin.