• Title/Summary/Keyword: 김지혜

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Neuronal Cell Protective Effects of Methanol Extract from Cheonggukjang Using in vitro System (In vitro system에서 청국장 메탄올 추출물의 신경세포 보호효과)

  • Jeong, Chang-Ho;Kwak, Ji-Hyun;Kim, Ji-Hye;Choi, Gwi-Nam;Jeong, Hee-Rok;Heo, Ho-Jin
    • Korean Journal of Food Science and Technology
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    • v.42 no.6
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    • pp.768-772
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    • 2010
  • In this study, the neuronal cell protective effects of methanol extract from cheonggukjang were evaluated. The proximate composition and total phenolics of the methanol extract were 40.95% crude protein, 22.49% crude fat, 15.99% nitrogen free extract, 7.91% moisture, 6.74% crude ash, 5.92% crude fiber, and 28.43 mg/g of total phenolics. Intracellular ROS accumulation resulting from $H_2O_2$ treatment of PC12 cells was significantly reduced when methanol extract was present in the media compared to PC12 cells treated with $H_2O_2$ only. In a cell viability assay using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium-bromide (MTT), the methanol extract showed protective effects against $H_2O_2$-induced neurotoxicity, and lactate dehydrogenase (LDH) release into the medium was also inhibited. Furthermore, the inhibitory effect of the methanol extract against acetylcholinesterase was dose-dependent.

Acetylcholinesterase Inhibitory Effect of Green Tea Extracts According to Storage Condition (저장 조건에 따른 녹차 추출물의 acetylcholinesterase(AChE) 저해 효과)

  • Kwak, Ji Hyun;Jeong, Chang-Ho;Kim, Ji Hye;Choi, Gwi Nam;Shin, Young-Hee;Lee, Seung-Cheol;Cho, Sung Hwan;Choi, Sung-Gil;Heo, Ho Jin
    • Korean Journal of Food Science and Technology
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    • v.41 no.4
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    • pp.435-440
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    • 2009
  • Acetylcholinesterase (AChE) inhibitors, which enhance cholinergic transmission by reducing the enzymatic degradation of acetylcholine, are the only source of the compound that is currently approved for the treatment of Alzheimer's disease (AD). In these experiments, the concentration samples of green tea extracts were 100, 500, and 1,000 ${\mu}g$/mL. Among them, the highest concentration (1,000 ${\mu}g$/mL) of fresh green tea extracts showed the most potent inhibitory effect on AChE by reducing more than 40% of enzyme activity, and in a concentration-dependent pattern. In addition, we examined the effect of other storing conditions on AChE inhibition. In order to maintain storage for 3 months, the materials were held at the certain storing conditions of temperature (room temperature, 4 and $-20^{\circ}C$) and for water activity (0.81, 0.69, and 0.23). In these storing conditions, the difference in temperature did not contribute to the AChE inhibitory effect. Our presented data showed that the AChE inhibitory effect was affected by the concentration of green tea extract and by water activity (0.81). These results suggest that green tea may serve as a potential dietary source of AChE inhibitor.

A Case Study of Developing E-Learning Contents of Agricultural Safety and Health based on Risk Assessment (위험성 평가에 기반한 농작업 안전관리 E-Learning 체험 프로그램 개발 사례 연구)

  • Kim, J.H.;Lee, K.S.;Kim, D.M.;Lee, K.S.;Kong, Y.K.;Jung, M.C.;Lee, Inseok
    • Journal of the Korean Society of Safety
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    • v.29 no.4
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    • pp.140-146
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    • 2014
  • This paper presents a case study to develop e-learning contents of agricultural safety based on the assessment of risks of 4 selected crops and stock farming: rice, potatoes, apples, tomatoes and stock raising. The aged farmers, who are main workforce of current Korean agriculture and relatively more vulnerable to various risks of agricultural work compared to younger workers, were considered as the main users of the contents in developing them. The safety guidelines were presented as simple as possible and the interfaces were designed to be simple and easy to use so that the older users can use it without much difficulty. In making the scenarios of the contents, risk assessments were carried out for each crop and stock farming with the focus being on occupational diseases rather than accidental injuries. To make the contents more attractive to the farmers, the functions requiring active responses from the users, such as answering simple questions, were included in the contents. Usability evaluation by experts of ergonomics and agricultural tasks were carried out in modifying the draft version, whereas formal usability test was not included in the case study. Though there are some limitations in the developed contents in the aspects of evaluation of usability and effectiveness, this case study shows the structured procedure of developing e-learning safety contents based on the risk assessments on agricultural tasks. The developed e-learning contents are expected to be used practically and easily in educating and training older farmers about safety and health of agricultural tasks.

An Efficient Dynamic Network Status Update Mechanism for QoS Routing (QoS 라우팅을 위한 효율적인 동적 네트워크 상태 정보 갱신 방안)

  • Kim, Jee-Hye;Lee, Mee-Jeong
    • Journal of KIISE:Information Networking
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    • v.29 no.1
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    • pp.65-76
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    • 2002
  • QoS routing is a routing technique for finding feasible path that satisfies QoS requirements required by application programs. Since QoS routing determines such paths in terms of dynamic network state, it satisfies the requirement of applications and increases the utilization of the network. The overhead is, however, generated by routers to exchange the information of the dynamic state of network. In order to reduce this protocol overhead, a timer based update mechanism is proposed in which router checks the change of the network status periodically and network state information is exchanged if the change is greater than a certain value. Using large update period makes, though, routing performance irresponsive to the parameters which determine the update of the network state of the router. In addition to this, large update period may result in inaccurate network state information at routers and cause resource reservation failure. The resource reservation failure generates additional overhead to cancel the resource reservation of the part of the path. In this paper, we propose mechanisms enhancing the existing network state update policy with respect to these two problems. Performance of the proposed schemes are evaluated through a course of simulation.

Associations between Serum 25-hydroxyvitamin D and Consumption Frequencies of Vitamin D Rich Foods in Korean Adults and Older Adults (한국 성인과 노인의 계절별 혈중 25-hydroxyvitamin D 농도와 비타민 D 급원식품 섭취빈도와의 관계)

  • Yu, Areum;Kim, Jihye;Kwon, Oran;Oh, Se-Young;Kim, Junghyun;Yang, Yoon Jung
    • Korean Journal of Community Nutrition
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    • v.19 no.2
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    • pp.122-132
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    • 2014
  • Objectives: This study was conducted to investigate the vitamin D status and to determine the association between serum 25-hydroxyvitamin D [25(OH)D] concentrations and consumption frequencies of vitamin D rich foods in Korean adults and older adults. Methods: Subjects were 10,374 adults and 2,792 older adults participating in the 2008-2009 Korea National Health and Nutrition Examination Survey (KNHANES). Consumption frequencies of vitamin D rich foods were estimated by using a qualitative food frequency questionnaire (FFQ). Eleven food items such as beef, egg, mackerel, tuna, yellow corvina, pollack, anchovy, mushroom, milk, yogurt, and ice cream were selected as vitamin D rich foods based on previous research. Results: The proportions of deficiency (< 12 ng/mL), inadequacy (12-20 ng/mL) and sufficiency (${\geq}20ng/mL$) of serum 25(OH)D concentrations from June to November and December to May in adults were 8.8%, 42.3%, 48.8%, and 28.2%, 52.8%, 19.1%, respectively. The proportions of deficiency, inadequacy and sufficiency of serum 25(OH)D concentrations from June to November and December to May in older adults were 10.1%, 32.4%, 57.5%, and 24.1%, 45.4%, 30.5%, respectively. The mean serum 25(OH)D concentrations in adults were positively related to the consumption frequencies of mackerel, anchovy, all fish, milk and milk dairy products. The mean serum 25(OH)D concentrations in older adults were positively related to the consumption frequencies of yellow corvina and negatively related to the consumption frequencies of ice cream. Conclusions: Our results suggest that Korean adults were more deficient in serum 25(OH)D concentrations than older adults. The consumption of vitamin D rich foods may affect vitamin D status in Korean adults. Further studies are required to confirm these findings.

The Accuracy Estimation of Profile Generation for Planning using 3D Topographical Model (3차원 지형모델을 이용한 설계용 프로파일 생성 정확도 평가)

  • Um, dae-yong;Lee, eun-soo;Kim, ji-hye
    • Proceedings of the Korea Contents Association Conference
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    • 2008.05a
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    • pp.892-896
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    • 2008
  • In construction work's process of a basic planning, we must carry out a topographical for construction reserved land and to the basis of this, production of profile is Indispensable factor for the purpose of every construction work such as road, rail way, canal and etc. From this research, the production of profile about construction reserved land, using topography information of numerical value topographical map produced by NGIS construction project, construct precision 3D topography model and from this, propose plans for utilizing by producing automatic profile. With the aim of this, abstract every layers of main facilities and altitude from numerical value topographical map and while producing 3D topography model by using this, we produce and product automatic profile from construct precision 3D topography. And about the produced profile's process, a topographical by mutual analysis was carried out to check whether the automatic produced profile's accuracy could be accepted at actual estimation and permissible accuracy. It is considered that the result of the research could be suggested as a new formation techniques concept which can reduce the designing time and expenses and increase the efficiency of planning in the basic design process for the construction.

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Evaluating the Effectiveness of Work with the Remote System in PACS Room (PACS실에서 원격시스템을 이용한 업무의 효율성 평가)

  • Kim, Ji-Hye;Lee, Jong-Woong;Lee, Seung-Jin;Dong, Kyung-Rae
    • Korean Journal of Digital Imaging in Medicine
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    • v.13 no.4
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    • pp.171-175
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    • 2011
  • Server and Pi view management, external image and internal image Copy Import business in PACS room is through the medical assistance. Import and Copy, and in particular the number of cases is increasing the number of import is a fast growing trend. Although the increase in workload With limited human resources to increase business efficiency so Remote system is using PACS room. This remote system will want to evaluate the effectiveness of using the service. Amount of data each 437.5 MB, Copy and Import time is to compare and evaluate sees by use 1 PC. 4 PC, 4 PC+ remote system. The use of the remote system before the January 2010 to June daily average waiting time and the use of the remote system after the January 2011 to June compared to a daily average patient waiting time, evaluate. Using the remote system in January 2011 to June Find out the average remote utilization. The biggest difference on the four copy and eight continued, Were performed two times faster by use 4 PC+ remote system than use 4 PC and four times faster than use 1 PC. Before using the remote system, the daily average wait time is 14.5 minutes after using the daily average 10.2 minutes, waiting time 30% of the existing waiting time was 4.3 minutes, to reduce. Using the remote system in January 2011 to June the average daily number of cases is 107 number and The number of remote and on average 35 cases with 32% in a day remote usage. The use of the remote system to Import, CD Copy and greatly increase the efficiency of their time could be. Hours due to efficiency could also reduce customer waiting time. As a result, the manpower and the use of a remote system over time to maximize efficiency in business hours, work was evaluated by.

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Study on Comparison of Dental Prosthesis Condition according by Educational Level (교육수준에 따른 구강 보철물 상태 비교 연구)

  • Kim, Hye Youn;Lee, Mi Hee;Kim, Ji Hye
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.123-129
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    • 2017
  • This study investigated the dental prosthesis condition from the sixth primitive data of Korea National Health and Nutrition Examination Survey to analyze and compare the necessity of existent dental prosthesis condition, dental bridge and dentures in order to determine the real oral health condition by educational level targeting adults aged over 20 years old. From the results, based on demographic-sociologic features, 32.2% of females were under elementary school graduation level, which was lower than males, and the educational level decreased with increasing age, and these trends were statistically significant. As for income level, 45.3% of university graduates had the highest income level and 77.4% of this age group were professionals, which was the highest percentage and was statistically significant. In terms of dental prosthesis condition according to educational level, the under elementary school graduation group had the most dental prosthesis and the greatest need for partial dentures and full dentures. As for the necessary number of fixed implants, the upper jaw had the most number of fixed implants and in the lower jaw, the under middle school graduation needed the most fixed implants.

Study on the Characteristics of Gray Water from an Apartment Complex for Reuse (재이용을 위한 공동주택 Gray Water의 특성 연구)

  • Park, Su Jeong;Kwon, Oh Sang;Tanaka, Hiroaki;Kim, Chang Soo;Kim, Eun Seok;Kim, Ji Hye;Jang, Seok Jea;Ahn, Kyung Hee
    • Journal of Korean Society on Water Environment
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    • v.29 no.6
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    • pp.847-851
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    • 2013
  • This study describes the results of an investigation conducted in order to characterize the quantity and quality of individual gray water streams. The highest pollutants concentrations were found in gray water originating from kitchen and laundry with $BOD_5$ concentrations in the order of several hundreds $mgl^{-1}$. In contrast to this, bathroom was regarded as a major contributor of Escherichia coli. Laundry gray water has higher pH, sodium, sulfate, anionic surfactants. Individual gray water types had different contribution to the overall daily discharge and relative pollutants loads. Kitchen, although accounting for only 13% of the total volume, was identified as a major source of microorganisms with Total coliforms, Escherichia coli, Fecal streptococcus taking up 82%, 74% and 54% of their relative daily load, respectively. The laundry gray water, although being responsible for 36% of the total daily discharge, was established as a significant contributor of sodium, sulfate, anionic surfactants and TOC (70%, 72%, 84% and 52%, respectively). But the laundry gray water was a minor source of microorganisms. Bathroom was found to be a major gray water producer, making up 51% of the flow, but constituted less than 50% of the relative daily load in most cases.

Potential effects of Novel Lactic Acid Bacteria on Fermentation Quality of Rye Haylage (신규 젖산균 첨가가 저 수분 호밀 사일리지의 발효 품질에 미치는 영향)

  • Choi, Ki Choon;Soundarrajan, Ilavenil;Srisesharam, Srigopalram;Park, Hyung Soo;Kim, Ji Hye;Jung, Jeong Sung;Kim, Hyun Seup
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.36 no.1
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    • pp.23-28
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    • 2016
  • The present study was carried out to explore the potential effects of novel lactic acid bacteria Pediococcus penticeous KCC-23 (KCC-23) and Lactobacillus plantarum KCC-24 (KCC-24) on rye haylage fermentation at National Institute of Animal Science, Cheonan province in Korea. The experiment contains three different groups such as control without lactic acid bacteria, rye haylage with KCC-23 and rye haylage KCC-24. After experimental periods, the content of crude protein, acid detergent fiber (ADF), neutral detergent fiber (NDF), the activity of total digestible nutrient (TDN) and In-vitro digestibility (IVD) was similar in control and LAB treated haylage (p<0.05). The pH was reduced in KCC-23 and KCC-24 treated rye haylage as compared to control (p<0.05). The lactic acid concentration in haylages was increased by L. plantarum KCC-23, and KCC-24 supplement. Whereas, the less amount of acetic acid and butyric acid was noted in KCC-23 and KCC-24 treated haylage as compared with control (p<0.05). The KCC-23 and KCC-24 were dominantly grown in experimental haylage as compared with control. It indicates, the addition of KCC-23, and KCC-24 enhances fermentation quality of haylages as compared control. The present study suggests that KCC-23 and KCC-24 are potent strains that were improving the fermentation process in rye haylage