• 제목/요약/키워드: ${\omega}-3$

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Omega-3 Fatty Fish의 섭취가 정상인의 Serum Insulin, Glucose에 미치는 영향 (Effects of Dietary Omega-3 Fatty Fish on Serum Insulin and Glucose in Normal Subjects)

  • 김영선
    • 한국식품영양학회지
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    • 제8권4호
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    • pp.318-324
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    • 1995
  • The purpose of this study was to Investigate the response of fasting serum glucose and basal insulin to dietary omega-3 fatty fish in normal subjects. Nineteen healthy female volunteer subjects were divided into two groups, depending on fish preference test. Low ap3 fatty acid group for 7 days received a experimental Inlet containing mackeral fish 100g. Calorie intake was 1780 kcal /day. The average 4ally u-3 fatty acid consumption from fish was 3.87g /day (1.03g EPA, 2.849 DHA) . High n-3 fatty acid group was given 7.74g maine u-3 fatty acid (200g mackeral fish) consisting of 2.06g EP45.68g DHA. Calorie intake was 1815 local /day Fasting blond serum glucose, insulin levels were measured at baseline, 7days after experimental diet. In the beginning the levels of fasting serum glucose, basal insulin were not different between both groups. There were no significant changes in fasting serum glucose, insulin levels by experimental diets. These data indicate that marine ar3 fatty acid consumption have no deleterious effect on glycemic control in normal subjects.

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Structure and Expression of a Perilla (Perilla frutescens Britt) Gene, PfFAD3, Encoding the Microsomal ${\omega}-3$ Fatty Acid Desaturase

  • Lee, Hyang-Hwa;Pyee, Jae-Ho
    • 한국약용작물학회지
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    • 제12권5호
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    • pp.424-427
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    • 2004
  • Microsomal ${\omega}-3$ fatty acid desaturase (FAD3) is an essential enzyme in the production of the n-3 polyunsaturated fatty acid ${\alpha}-linolenic$ acid during the seed developing stage. To understand the regulatory mechanism of the gene encoding the ${\omega}-3$ fatty acid desaturase, a genomic fragment corresponding to the previously isolated perilla seed PfFAD3 cDNA was amplified from perilla (Perilla frutescens Britt) by GenomeWalker PCR. Sequence analysis of the fragment provided with identification of a 1485-bp 5'-upstream region and a 241-bp intron in the open reading frame. To determine the tissue-specificity of the PfFAD3 gene expression, the 5'-upstream region was fused to the ${\beta}-glucuronidase$ (GUS) gene and incorporated into Arabidopsis thaliana. Histochemical assay of the transgenic plants showed that GUS expression was restricted to seed and pollen, showing that PfFAD3 gene was exclusively expressed in those tissues.

Synthesis and in vitro cytotoxicity of a homologous series of 5-halosubstituted $1,3-Bis(\omega-cyanoalkyl)$uracil analogues

  • Kim, Jack-C.;Dong, Eun-Soo;Park, Jin-Il;Kim, Young-Hyeun;Choi, Soon-Kyu
    • Archives of Pharmacal Research
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    • 제19권1호
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    • pp.62-65
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    • 1996
  • A homologous series of twenty, hitherto unreported, analogues of 5-halosubstituted $1, 3-Bis(\omega-cyanoalkyl)uracil$acyclic nucleosides were synthesized by the series of alkylation reactions of 5-halouracils with the corresponding chloroacetonitrile, chloropropionitrile, chlorobutyronitrile and 5-chlorovaleronitrile $(Cl-(C_ 2)_n-CN: n=l, 2, 3, 4)\; in\; anhydrous\; DMSO\; (or DMF)/K_2CO_3(or NaH)\; under\; 75^{\circ}C$ temperature. Antitumor activities for the synthesized compounds were determined against three cell lines (FM-3A cell, P-388 cell and U-938 cell lines). The compounds that exhibited moderate activity to significant activity, included la-b, 2a-b, 3a-c, and 4a, whose compounds were active against P-388, FM-3A and U-937 cell lines with the compounds la, lb, and 2a, showing significant antitumor activity (inhibitory concentrations $(IC_{50})$ ranged from 2.2 to $7.0\mug/ml$). Their strucrure-activity relationship did not show any activity differences in their effective chain length (methyl, ethyl, propyl, butyl) in 1, 3-bis(.omega.-cyanoalkyl) uracils.

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Rhizobium fredii Pectate Lyase 유전자의 Marker-Exchange 변이 (Marker-Exchange Mutagenesis of Pectate Lyase Gene in Rhizobium fredii)

  • 정민화;박용우;윤한대
    • 한국미생물·생명공학회지
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    • 제19권3호
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    • pp.222-227
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    • 1991
  • Rhizobium fredii USDA193은 대두(Peking)의 근모 세포벽에 침투하여 근류를 형성한다. 본 실험에서는 전보 (1)에서 분리 보고한 R.fredii의 pectate lyase 유전자 clone(SY1)으로부터 $\Omega$변이를 시켰다. 이것을 R.fredii USDA193에 다시 marker-exchange시켜 얻은 변이주(R.fredii USDA193$\Omega$와 R.fredii USDA193omega1)의 pectate lyase 활성이 완전히 block되지 못하였다. R.fredii 내에서는 다른 종류의 pel 유전자가 존재하 것으로 생각되며 pelB 및 pelE의 Rhizobium mutants들은 근류형성 초기단계에서 직접적으로 영향을 미치지 못하였다.

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Analysis and Approximation of Linear feedback control problems for the Boussinesq equations

  • 최영미;이형천
    • 한국전산응용수학회:학술대회논문집
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    • 한국전산응용수학회 2003년도 KSCAM 학술발표회 프로그램 및 초록집
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    • pp.6-6
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    • 2003
  • In this work we consider the mathematical formulation and numerical resolution of the linear feedback control problem for Boussinesq equations. The controlled Boussinesq equations is given by $$\frac{{\partial}u}{{\partial}t}-{\nu}{\Delta}u+(u{\cdot}{\nabla}u+{\nabla}p={\beta}{\theta}g+f+F\;\;in\;(0,\;T){\times}\;{\Omega}$$, $${\nabla}{\cdot}u=0\;\;in\;(0,\;T){\times}{\Omega}$$, $$u|_{{\partial}{\Omega}=0,\;u(0,x)=\;u_0(x)$$ $$\frac{{\partial}{\theta}}{{\partial}t}-k{\Delta}{\theta}+(u{\cdot}){\theta}={\tau}+T,\;\;in(0,\;T){\times}{\Omega}$$ $${\theta}|_{{\partial}{\Omega}=0,\;\;{\theta}(0,X)={\theta}_0(X)$$, where $\Omega$ is a bounded open set in $R^{n}$, n=2 or 3 with a $C^{\infty}$ boundary ${\partial}{\Omega}$. The control is achieved by means of a linear feedback law relating the body forces to the velocity and temperature field, i.e., $$f=-{\gamma}_1(u-U),\;\;{\tau}=-{\gamma}_2({\theta}-{\Theta}}$$ where (U,$\Theta$) are target velocity and temperature. We show that the unsteady solutions to Boussinesq equations are stabilizable by internal controllers with exponential decaying property. In order to compute (approximations to) solution, semi discrete-in-time and full space-time discrete approximations are also studied. We prove that the difference between the solution of the discrete problem and the target solution decay to zero exponentially for sufficiently small time step.

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STABILITY RESULTS OF POSITIVE WEAK SOLUTION FOR SINGULAR p-LAPLACIAN NONLINEAR SYSTEM

  • KHAFAGY, SALAH;SERAG, HASSAN
    • Journal of applied mathematics & informatics
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    • 제36권3_4호
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    • pp.173-179
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    • 2018
  • In this paper, we investigate the stability of positive weak solution for the singular p-Laplacian nonlinear system $-div[{\mid}x{\mid}^{-ap}{\mid}{\nabla}u{\mid}^{p-2}{\nabla}u]+m(x){\mid}u{\mid}^{p-2}u={\lambda}{\mid}x{\mid}^{-(a+1)p+c}b(x)f(u)$ in ${\Omega}$, Bu = 0 on ${\partial}{\Omega}$, where ${\Omega}{\subset}R^n$ is a bounded domain with smooth boundary $Bu={\delta}h(x)u+(1-{\delta})\frac{{\partial}u}{{\partial}n}$ where ${\delta}{\in}[0,1]$, $h:{\partial}{\Omega}{\rightarrow}R^+$ with h = 1 when ${\delta}=1$, $0{\in}{\Omega}$, 1 < p < n, 0 ${\leq}$ a < ${\frac{n-p}{p}}$, m(x) is a weight function, the continuous function $b(x):{\Omega}{\rightarrow}R$ satisfies either b(x) > 0 or b(x) < 0 for all $x{\in}{\Omega}$, ${\lambda}$ is a positive parameter and $f:[0,{\infty}){\rightarrow}R$ is a continuous function. We provide a simple proof to establish that every positive solution is unstable under certain conditions.

Active Queue Management using Adaptive RED

  • Verma, Rahul;Iyer, Aravind;Karandikar, Abhay
    • Journal of Communications and Networks
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    • 제5권3호
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    • pp.275-281
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    • 2003
  • Random Early Detection (RED) [1] is an active queue management scheme which has been deployed extensively to reduce packet loss during congestion. Although RED can improve loss rates, its performance depends severely on the tuning of its operating parameters. The idea of adaptively varying RED parameters to suit the network conditions has been investigated in [2], where the maximum packet dropping probability $max_p$ has been varied. This paper focuses on adaptively varying the queue weight $\omega_q$ in conjunction with $max_p$ to improve the performance. We propose two algorithms viz., $\omega_q$-thresh and $\omega_q$-ewma to adaptively vary $\omega_q$. The performance is measured in terms of the packet loss percentage, link utilization and stability of the instantaneous queue length. We demonstrate that varying $\omega_q$ and $max_p$ together results in an overall improvement in loss percentage and queue stability, while maintaining the same link utilization. We also show that $max_p$ has a greater influence on loss percentage and queue stability as compared to $\omega_q$, and that varying $\omega_q$ has a positive influence on link utilization.

사료내 아마종실과 사료첨가물질의 조합첨가가 난황내 지방산 함량과 산란능력에 미치는 영향

  • 이준엽;이선연;오상집
    • 한국가금학회:학술대회논문집
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    • 한국가금학회 2002년도 가을 학술발표논문집
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    • pp.128-129
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    • 2002
  • 본 연구결과로 $\omega$-3 지방산을 포함한 지방산의 계란내 이행정도는 flaxseed의 첨가와 지방산대사에 영향을 미치는 미량 사료 첨가물질의 병용첨가로 변화되는 것으로 나타났으며, 특히 생균물질과 lecithin의 생리적 기능에 의한 계란내 $\omega$-3 지방산의 급증이 특이적인 것으로 나타났다. 그러나 미량 사료 첨가물질의 지방대사 조절기전에 관해서는 추가연구가 필요한 것으로 판단된다.

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20개(個) 조경수종(造景樹種)의 형성층전기저항치(形成層電氣抵抗値)의 수종간(樹種間) 차이(差異)와 계절적(季節的) 변화(變化) (Differences between Species and Seasonal Changes in Cambial Electrical Resistance of Twenty Ornamental Tree Species)

  • 이경준;한심희;정용선
    • 한국산림과학회지
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    • 제86권4호
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    • pp.415-421
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    • 1997
  • 본 연구는 Shigometer를 조경수목의 건강도 측정에 활용하기 위하여 계절별로 형성층 부근의 전기저항치를 조사하여 수종별 평균치를 구하고, 관목, 침엽수교목, 활엽수교목의 개엽, 개화, 생장정지등 계절별 생장에 따른 전기저항 특성을 상호 비교하기 위하여 수행하였다. 1996년 3월부터 11월까지 경기도 수원시 서울대학교 농업생명과학대학 교내에 식재되어 있는 조경수 20 수종을 대상으로 Shigometer를 이용하여 각 수목의 형성층의 전기저항치(CER)를 개화와 개엽시기인 3월에서 5월까지 주 1회씩, 6월부터 10월까지 월 1회씩, 그리고 11월에는 2주마다 측정하였다. 수종별로 건강한 4개체를 사용하였으며, 매회 개체당 4반복으로 조사하였다. 모든 수종이 3월에 높은 CER을 보이다가 4월부터 감소하기 시작하여 5월부터 8월 사이에 가장 낮은 값을 보였으며, 9월부터 다시 증가하기 시작하여 11월에는 3월과 같은 수준의 높은 값을 나타냈다. 전체 20 수종 중에서 년 평균 CER 값이 가장 낮은 수종은 $5.5k{\Omega}$의 메타세코이아였으며 가장 높은 수종은 $22.7k{\Omega}$$22.9k{\Omega}$의 박태기나무와 쥐똥나무였다. 여름철 (6~8월)에 가장 낮은 CER 값을 보여준 수종은 등나무 ($2.4k{\Omega}$)였으며, 그 다음은 메타세코이아($2.5k{\Omega}$)이었다. 11월 혹은 3윌 중에 가장 높은 CER 값을 가진 나무는 사철나무($46.8k{\Omega}$)이었고 그 다음은 쥐똥나무($45.0k{\Omega}$)이였다. 봄철 개엽시기에 맞추어 대부분 수종의 CER이 감소하였으며, 특히 관목에서 현저히 나타났다. 개화시기에도 많은 수종의 CER이 감소하였는데 특히 개화량이 많은 관목과 활엽수 교목에서 관찰되었다. 관목, 활엽수 교목, 침엽수 교목간의 비교에서는 관목의 평균 CER치가 교목보다 높은 편이었으며, 상록수의 계절간 변화폭은 낙엽수보다 적게 나타났다. 메타세코이아는 낙엽성 침엽수이지만 년간 평균치가 가장 낮았다.

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