Hand characteristics related with structural properties of fabrics have something to do with mechanical properties of fabric. In this study, the mechanical properties and hand characteristics have been analyzed according to fabric structural parameters such as the weave structure and the linear density of weft of cotton fabric. Mechanical properties have been used by KES-FB system which measures hand characteristics and mechanical properties of fabric. Linear density of weft, tensile, bending, and shear properties are decreasing with increasing weft linear density, and there is no considerable effects on compression and surface properties. In case of formability with weft linear density, B/W, 2HG/G, 2HB/B, 2HB/W, $\sqrt[3]{B/W}$, $\sqrt{2HB/W}$, W/T except MMD/SMD, WC/T, and WC/W have been effected. There is a high correlation between the crimp, tightness, hand, formability and mechanical properties specially tensile linearity, bending, shear, and compression properties. The weft crimp influences the bending rigidity, shear properties, and the tightness which have effects on the tensile linearity, bending, shear, compression properties, hand, and formability.