• Journal of Oriental Neuropsychiatry
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• v.32 no.3
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• pp.141-154
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• 2021

Objectives: Pharmacopuncture is a Korean medicine treatment that combines acupuncture and herbal medicines. The aim of this study was to investigate the current usage status of pharmacopuncture for insomnia among Korean medicine doctors (KMDs). Methods: We conducted a self-reporting online survey targeting KMDs from February 23 to March 15, 2021 with cooperation of the Association of Korean Medicine. Responses of 957 KMDs were analyzed. Results: Types of pharmacopuncture mainly used in treatment for insomnia were placenta pharmacopuncture and Hwangryunhaedok-tang pharmacopuncture. Cephalic and facial region were preferred as the treatment site. For one treatment, total usage of pharmacopuncture was more than 0.5 cc but less than 1 cc. Among respondents, the largest number of respondents thought that clinical experience and patient symptoms were important as selection criteria of acupoints using Pharmacopuncture for insomnia. Average treatment duration of using Pharmacopuncture for insmonia was more than 4 weeks. Most KMDs preferred treatment for one to four times a week regarding the treatment cycle. The use of Pharmacopuncture for insomnia was recognized as having a good effect, although other KMDs were concerned about the insufficient evidence and the high cost due to non-reimbursement of pharmacopuncture therapy. Conclusions: In order to activate pharmacopuncture treatment for insomnia, it is necessary to secure effectiveness and safety through basic research, create evidence through clinical research, and reduce costs for patients.

• Journal of IKEEE
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• v.25 no.3
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• pp.467-472
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• 2021

Stable operation of semiconductor devices is needed even at high temperatures. Among the structures of semiconductor devices, the area that can cause unstable electrical responses at high temperatures is the contact layer between the metal and the semiconductor. In this study, the effect of annealing conditions included in the process of forming a contact layer of nickel silicide(NiSix) on a p-type SiC layer on the specific contact resistance of the contact layer and the total resistance between the metal and the semiconductor was investigated. To this end, a series of electrodes for TLM (transfer length method) measurements were patterned on the 4 inch p-type SiC layer under conditions of changing annealing temperature of 1700 and 1800 ℃ and annealing time of 30 and 60 minutes. As a result, it was confirmed that the annealing conditions affect the resistance of the contact layer and the electrical stability of the device.

• Journal of Fashion Business
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• v.25 no.2
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• pp.63-79
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• 2021

In order to expand the overseas market of the Korean fashion industry, it is necessary to investigate the fashion-related purchases and fashion consciousness of Muslim women, who are increasingly attracting attention as global fashion consumers. Therefore a survey was conducted to identify the fashion design preferences and fashion consciousness of Malaysian Muslim women. A total of 245 responses were collected and analyzed. The survey included questions on demographic characteristics, fashion product purchases, design preferences and environmental awareness. The data were analyzed through frequency, average and standard deviation. The analysis showed that the majority of respondents were young Malaysian Muslim women in their 20s and 30s. They preferred a modern, Sophisticated, and sporty image, and their preference for unpatterned fabrics was high. When choosing fashion products, these women seek to both pursue fashion trends and comply with Islamic laws. When the women buy clothes, they consider practicality and design elements. The women also collected fashion trend information through SNS and the Internet, and ues this information to purchase fashion products through the Internet and shopping malls. This study was based on a practical survey of local consumers. Therefore, it is expected that the results can be used as data for fashion-related studies and to expand overseas markets to reach Muslim women in Southeast Asia.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.3
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• pp.217-225
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• 2021

Neuropathic pain (NP) that contributes to the comorbidity between pain and depression is a clinical dilemma. Neuroinflammatory responses are known to have potentially important roles in the initiation of NP and depressive mood. In this study, we aimed to investigate the effects of paeoniflorin (PF) on NP-induced depression-like behaviors by targeting the hippocampal neuroinflammation through the toll-like receptor 4 (TLR4)/nuclear factor-kappa B (NF-κB) signaling pathway. We used a murine model of NP caused by unilateral sciatic nerve cuffing (Cuff). PF was injected intraperitoneally once a day for a total of 14 days. Pain and depression-like behavior changes were evaluated via behavioral tests. Pathological changes in the hippocampus of mice were observed by H&E staining. The levels of proinflammatory cytokines in the hippocampus were detected using ELISA. Activated microglia were measured by immunohistochemical staining. The TLR4/NF-κB signaling pathway-associated protein expression in the hippocampus was detected by western blotting. We found that the PF could significantly alleviate Cuff-induced hyperalgesia and depressive behaviors, lessen the pathological damage to the hippocampal cell, reduce proinflammatory cytokines levels, and inhibit microglial over-activation. Furthermore, PF downregulated the expression levels of TLR4/NF-κB signaling pathway-related proteins in the hippocampus. These results indicate that PF is an effective drug for improving the comorbidity between NP and depression.

• Journal of Digital Convergence
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• v.19 no.12
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• pp.397-404
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• 2021

Product image location in search engine advertising plays an important role in consumer perception when the product is relatively low involved and has functional value. The purpose of this research is to investigate the interaction effects of product image location and product type on advertising effectiveness. Building on the literature of location effects, we show that for products for which heaviness is considered a positive attribute, product image placed on the right are preferred. To test hypotheses, a 2(product image location: left vs. right) × 2(product type: single vs. bundle) experiment is conducted and a total of 144 paricipants took part in the experiment. The results revealed that respondents show higher brand attitude and purchse intention toward a bundle product's advertising with product image place on the right. The results provide implications and suggestions for improving search engine advertising and marketing strategies.

• Journal of Engineering Education Research
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• v.24 no.6
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• pp.3-19
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• 2021

This study aimed to introduce a case study of a basic engineering design course using the ENACT model for fostering social responsibility of engineers, and to investigate the educational effects of the course. Since the ENACT model was designed to encourage STEM college students to pursue responsible problem solving based on their understanding of socioscientific issues, we assumed that it would be beneficial for engineering students to foster their social responsibility as well as their understanding of science/engineering-related issues. A total of 49 engineering students who enrolled in the course participated in the study. Data included students' course artifacts, reflection papers, and responses to survey questionnaires. Results indicated that the students became more aware of nature of science and technology after the program, and began to solve the problems while considering the views of multiple stakeholders. They highly valued the experience of communicating with others as engaging in the civic activities. They also expressed high satisfaction and feeling of achievement on the course learning. We expect the ENACT model to be an effective teaching guideline that fosters the social responsibility of engineering students and furthermore, engineering ethics.

• Journal of Obesity & Metabolic Syndrome
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• v.27 no.4
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• pp.248-253
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• 2018

Background: Sirtuins mediate metabolic responses to nutrient availability and slow aging and accompanying decline in health. This study was designed to assess the expressions of sirtuin1 (SIRT1) and sirtuin3 (SIRT3) in the liver and hypothalamus after duodenal-jejunal bypass (DJB) surgery in rats. Methods: A total of 38 rats were randomly assigned to either sham group (n=8) or DJB group (n=30). DJB group was again divided into three groups according to the elapsed time after surgery (10 weeks, DJB10; 16 week, DJB16; 28 week, DJB28). The mRNA and protein expressions of SIRT1 and SIRT3 in the liver and hypothalamus were measured by reverse transcription polymerase chain reaction, Western blot, and immunohistochemistry analyses. $NAD^+/NADH$ ratio was also measured. Results: We found increased mRNA and protein expression levels of SIRT1 in the liver of DJB16 and DJB28 groups compared with those of sham group. The mRNA and protein expressions of SIRT3 in the liver of DJB group increased proportionally to the elapsed time after DJB surgery. The mRNA expression levels of SIRT1 in the hypothalamus increased in DJB16 and DJB28 groups and protein expression levels of SIRT1 in the hypothalamus increased in DJB10, DBJ16, and DJB28 groups compared with sham group. We observed that mRNA and protein levels of SIRT3 in the hypothalamus of DJB group were not changed. Conclusion: This study proves that DJB increases SIRT1 and SIRT3 expressions in the liver and SIRT1 expression in the hypothalamus. These results suggest the possibility of sirtuins being involved in bypass surgery-induced metabolic changes.

• Korean Journal of Breeding Science
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• v.43 no.1
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• pp.1-13
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• 2011

Low temperature stress is one of the major negative factors affecting vegetative and reproductive growth of rice. To better understand responses of rice plants to low temperature we analyzed transcriptome expression patterns in glumous flower of cold-tolerant japonica rice variety, Stejaree45, and cold-susceptible variety, HR19621-AC6 at booting stage under cold water irrigation. A total of 2,411 probes were differentially expressed by low temperature in glumous flowers of the two varieties. Some important genes involved in hormone biosynthesis showed variety-specific regulation. Expression of GA20ox3 and GA2ox, among the genes involved in GA biosynthesis, was regulated differentially in the two varieties. Among the genes involved in IAA biosynthesis, YUCCA1 and TAA1:1 showed variety-specific regulation. Among the genes involved in cytokinin biosynthsis and signaling, expression of LOG, HK1 and HK3 was significantly down-regulated only in the cold-susceptible variety. Among the genes involved in ABA biosynthesis, NSY and AAO3 were down-regulated only in the cold-tolerant variety. In general, genes involved in GA, IAA and cytokinin biosynthesis responded to cold temperature in such a way that capacity of those bioactive hormones is maintained at relatively higher levels under cold temperature in the cold-tolerant variety, which can help minimize cold stress imposed to developing reproductive organs in the cold-tolerant variety.

• The Journal of the Korea Contents Association
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• v.19 no.4
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• pp.227-240
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• 2019

This study, To find practical problems with the imaging of webtoons, propose their alternatives, and secure the professionalism of research along with 22 field experts including writers, directors, producers, investors and importance survey was carried out with 30 practical experts. There were four major interview areas including the stages of imaging production, investment and support for imaging, difficulties with imaging, and improvement of production methods and systems. Responses were collected from a total of 13 questions. All agreed that the biggest difficulty with imaging was a low level of collaboration, but they had different ideas about an ideal collaboration system. A low level of collaboration was mainly attributed to a shortage of professionals and lack of communication. There should be an effort to bring up such experts in three major areas including professional adaptation writers, professional IP producers, and investment agencies specialized in content.

• Journal of Environmental Health Sciences
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• v.45 no.2
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• pp.164-172
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• 2019

Objectives: This study's purpose is finding children's activity spaces that demand environmental safety management. Methods: The method of this study is analysing children's life patterns based on a questionnaire survey. Results: This study analyzed children's life patterns through a questionnaire survey. In total, 2,447 questionnaires were provided to analyze children's life patterns. The results of the questionnaire indicated a highly simple form because many children generally stayed in their home (66%) or nursery facility (2%). In the case of other facilities, playground was ranked first and amusement park was ranked second. In addition, kids cafe (including play facilities installed in shopping centers, etc.), library, and internet cafe were among the responses. Conclusions: The priority for new high-maintenance children's activity spaces are academy (rank 1), kids cafe (rank 2), indoor playground (rank 3).