• Asian Pacific Journal of Cancer Prevention
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• v.16 no.6
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• pp.2459-2463
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• 2015

Background: To investigate the expression and clinical significance of zinc finger protein 217 (ZNF217) in human colorectal carcinoma (CRC). Materials and Methods: The expression of ZNF217 in 60 CRC tissues and matched tumor adjacent tissues, collected between January 2013 and June 2014, was assessed immunohistochemically. The relationship between the expression of ZNF217 and clinicopathlogical features was analyzed by Pearson chi-square test. In addition, siRNA was used to down-regulate the expression of ZNF217 in CRC cells. The effects of ZNF217 for cell migration and invasion were measured by wound healing assay and transwell assay, respectively. Results: The expression level of ZNF217 was significantly higher in CRC tissues than in tumor adjacent tissues (p<0.05), positively correlating with tumor size, lymphatic metastasis and advanced TNM stage (p<0.05). Down-regulation of ZNF217 in CRC cells could significantly suppress cell migration and invasion. Conclusions: ZNF217 is overexpressed in colorectal carcinoma tissues and is associated with tumor malignant clinicopathological features. ZNF217 may promote CRC progression by inducing cell migration and invasion.

• Proceedings of the KSME Conference
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• 2001.06b
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• pp.228-234
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• 2001

NTMS(Non-contact Tilted-angle Measuring System) is developed by using the principle that the magnetic field of an anisotropic magnet's inner space is uniform and it's possible to measure the strength of the magnetic field using a linear hall effect sensor. In order to implement the caliper system of the geometry PIG(Pipeline Inspection Gauge) which has high accuracy and proper output voltage of the hall sensor without additional driving module or a signal amplifier, it is necessary to consider the size of the magnet, the inner space and back-yoke and the position of pin-hole in the magnet. So the optimal design method of the caliper system is proposed through analysis of NTMS's magnetic field adopting a FEM(Finite Element Method). The experimental results show that the developed caliper system can be used for the geometry pig with good performances.

• Molecules and Cells
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• v.41 no.12
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• pp.1024-1032
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• 2018

The central mechanisms coordinating growth and sexual maturation are well conserved across invertebrates and vertebrates. Although mutations in the gene encoding makorin RING finger protein 3 (mkrn3) are associated with central precocious puberty in humans, a causal relationship has not been elucidated. Here, we examined the role of mkrn1, a Drosophila ortholog of mammalian makorin genes, in the regulation of developmental timing. Loss of MKRN1 in $mkrn1^{exS}$ prolonged the $3^{rd}$ instar stage and delayed the onset of pupariation, resulting in bigger size pupae. MKRN1 was expressed in the prothoracic gland, where the steroid hormone ecdysone is produced. Furthermore, $mkrn1^{exS}$ larvae exhibited reduced mRNA levels of phantom, which encodes ecdysone-synthesizing enzyme and E74, which is a down-stream target of ecdysone. Collectively, these results indicate that MKRN1 fine-tunes developmental timing and sexual maturation by affecting ecdysone synthesis in Drosophila. Moreover, our study supports the notion that malfunction of makorin gene family member, mkrn3 dysregulates the timing of puberty in mammals.

• Korean Journal of Human Ecology
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• v.23 no.3
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• pp.483-500
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• 2014

Survey was conducted on 201 female college students who in at the university to analyze perceptions and satisfaction levels about their body shapes. Results revealed that the Chinese female students recognized that they had broader shoulder angles, bigger breasts and longer calves and legs than Korean female students whereas the Korean female students had larger hip and thigh circumference than Chinese female students. It was found that the Chinese female students had preference for drooping shoulders while the Korean students perceived themselves as thinner and have longer arms, fingers, waist measurement, torso thickness, calves, feet and legs are ideal body shapes. The results of this study show that body weight, height and chest size have a lot of influence on it and the Korean female students were less satisfied their body shape compared with the Chinese female college students. The correlation analysis indicated that body shapes were an important indicator of satisfaction and the thinner the body shape, chest, thigh, waist, finger, arms, the greater the satisfactions.

• Journal of Institute of Control, Robotics and Systems
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• v.6 no.4
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• pp.327-332
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• 2000

In this paper, a new multi-fingered robot hand using ultrasonic motors and its control system are developed. The developed robot hand has four fingers and fifteen articulated joints. The distal joint of each finger is directly driven by ultrasonic motor and all joints except the distal joint has low transmission gear mechanism with the motor. The developed robot hand has several advantages in size compared to a hand using conventional DC motors, and in performance compared to a hand using tendons to drive joints. A VME-bus based hand control system and ultrasonic motor driver are also developed. The performance of the hand is confirmed by using the developed control system in real-time.

• Journal of the Korean Institute of Telematics and Electronics
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• v.21 no.5
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• pp.17-26
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• 1984

This paper reports the design methods and fabrication processes developed for a TV-lF SAW filter. The windowing method, the frequency sampling method, and the time sampling method were studied and compared to obtain a satisfactory initial impulse response. To obtain high attenuation near the trap frequency, diffraction effects were compensated. The 4fo sampling technique was used for avoiding multiple reflections at finger edges and obtaining an asymmetrical frequency response, and effective photolithographic techniques were used for electrode fingers with 11.2$\mu$ width. The developed filter is of sufficiently small size to be cost-effective and satisfies the industry specifications required for mass production.

• Journal of the Korean Professional Engineers Association
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• v.17 no.3
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• pp.22-31
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• 1984

Sardine ant mackerel so called dark muscled fish have been underutilized due to the disadvantages in bloody meat color, high content of fat, and postmortem instability of protein. Recent efforts were made to overcome these defects and develope new types of product such as texturized protein concentrates and dark muscle eliminated minced fish. Approach of this study is based on the rapicl dehydration of foamed fish-starch paste by dielectric heating. In process comminuted sardine meat was washed more than three times by soaking and decanting in chilled water and finally centrifuged. The meat was ground in a stone mortar added with adequate amounts of salt, foaming agent, and other ingredients for aid to elasticity and foam stability. The ground meat paste was extruded in finger shape and heated in a microwave oven to give foamed, expanded, and porous solid structure by dehydration. Dielectric constant ($\varepsilon$′) and dielectric loss ($\varepsilon$") vcalues of sardine meat paste were influenced by wavelength and moisture level. Those values at 100KHz and 15MHz were ranged 2.25∼9.86 ; 2.22∼4.18 for $\varepsilon$′ and 0.24∼19.24 ; 0.16∼1.25 for $\varepsilon$", respectively, at the moisture levels of 4.2∼13.8％. For a formula for fish-starch paste preparation, addition of 20∼30% starch (potato starch) to the weight of fish meat, 2∼4% salt, and 5∼10% soybean protein was adequate to yield 4∼5 folds of expansion in volume when heated. Addition of egg yolk was of benefit to micronize foam size and better crispness. In order to provide better foaming and dehydration, addition of 0.2∼0.5% sodium bicarbonate foaming agent, was proper to result in foam size of 0.5∼0.7mm and foam density of 200∼400/$\textrm{cm}^2$ which gave a good crispness.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.558-564
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• 2021

The water purifier market has increased rapidly in recent years. The welding technology of the evaporator is a key component that determines the level of ice production and the cold water performance of an ice purifier. The finger type evaporator of an ice purifier can remove ice and is divided largely into an instant heat method and a hot gas method. In the hot gas type evaporator, particularly during the production process, the pinhole phenomenon inside the copper pipe and clogging problems occur intermittently when welding high-pressure pipes due to the high-temperature oxygen welding. Its use in a water purifier can cause a problem in that ice and cold water do not form, and repairs cannot be made on site. To solve this problem, in this study, a cap jig was applied to improve the welding defect of the hot gas evaporator. In addition, the oxygen welding flame size was adjusted so that the heat source could be well supplied to the cap jig, and the effectiveness was confirmed through a wave pressure test, a test, and a thermal shock test.

• Journal of Korea Multimedia Society
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• v.13 no.9
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• pp.1337-1347
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• 2010

Fingerprint recognition is a biometric technology to identify individual by using fingerprint features such ridges and valleys. Most fingerprint systems perform the recognition based on minutiae points after acquiring a fingerprint image from contact type sensor. They have an advantage of acquiring a clear image of uniform size by touching finger on the sensor. However, they have the problems of the image quality can be reduced in case of severely dry or wet finger due to the variations of touching pressure and latent fingerprint on the sensor. To solve these problems, the contactless capturing devices for a fingerprint image was introduced in previous works. However, the accuracy of detecting minutiae points and recognition performance are reduced due to the degradation of image quality by the illumination variation. So, this paper proposes a new LDP-based fingerprint recognition method. It can effectively extract fingerprint patterns of iterative ridges and valleys. After producing histograms of the binary codes which are extracted by the LDP method, chi square distance between the enrolled and input feature histograms is calculated. The calculated chi square distance is used as the score of fingerprint recognition. As the experimental results, the EER of the proposed approach is reduced by 0.521% in comparison with that of the previous LBP-based fingerprint recognition approach.

• Science of Emotion and Sensibility
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• v.13 no.4
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• pp.703-710
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• 2010

In this study, a tactile stimulator was developed to resolve some problems from the previous version of the system such as system configuration, inappropriate stimulation control and additional problems. The developed tactile stimulator consists of control unit, drive unit and vibrator unit. The control unit was controlled by E-Prime software to generate appropriate vibration pulses. The drive unit supplies enough energy to the vibrator to generate effective stimulation pulses. The vibrator unit consists of small coin type vibrator and velcro, and was made to be attached at the hand easily. The developed tactile stimulator was designed by small-size, light-weight, low-power, simple-fabrication, max 35 channels and little delay time from instruction signal of E-Prime software to vibrator. The duration and magnitude of stimulation was controlled by 10 grades and the problems concerning stimulation control were compensated by wideband frequency ranges. Additionally, the electrical safety was ensured by low voltage operation. Vibrator was made to be attached on finger as well as on any part of the subject. Since this tactile stimulator is developed based on E-Prime software which is widely used in cognitive science, it is believed that this stimulator be suitable for the wide application of cognitive science study.