• 한국미생물·생명공학회지
• /
• 제10권3호
• /
• pp.227-232
• /
• 1982

삶은 콩을 이용한 고체 배지상에서 Aspergillus oryzae의 성장 속도를 측정하는 방법에 대하여 연구하고 이들 방법을 대두와 루우핀콩 배지에서의 균 성장 특성을 비교하는데 적용하였다. 여러가지 배지 조건에서 배양 기간에 따른 균체 colony의 형성시간 크기변화, $\alpha$-아미노 질소함량의 변화, 포자형성 시간 및 균사길이의 변화등을 측정 비교하였다. 배지의 종류에 따라 Aspergillus oryzae는 특정한 균체 colony 형성시간을 나타내었으며 colony 형성후 부터는 colony 직경의 크기는 배양시간에 따라 직선적으로 증가하였다. 균체colony 직경은 배지중의 $\alpha$-아미노 질소함량과 높은 직접적인 상관관계를 나타내었으나 배지의 수분함량이 변하면 이러한 상관관계가 성립되지 않았다. 오히려 배지의 수분함량이 증가하면(60%-85%) $\alpha$-아미노 질소함량은 증가하나 colony 직경은 감소하는 역 관계를 나타내었다. 일반적으로 Aspergillus oryzae는 삶은 루우핀콩 페이스트에서 최초 성장 속도가 대두보다 발랐으며. 루우핀콩 배지에서의 colony 형성시간이 24시간인데 반해 대두에서는 44.4 시간이 걸렸다. 그러나 colony 형성이후의 성장 속도는 대두에서 더 빠르게 나타나 대두의 경우 8.83mm/day 인데 반하여 루우핀 콩에서는 7.05mm/day이었다. spore 형성 시간은 colony 형성 시간과 깊은 상관관계를 나타내었으며 일반적으로 루우핀콩에서 spore 형성 시간이 짧았다. 콩의 표면에서 균사길이를 측정하는 방법은 간단하고 빨리 균체의 성장 속도를 비교할수 있 었으며 특히 콩의 구조와 형태가 균체 성장에 미치는 영향을 조사하는데 편리하였다. 본 실 험에서는 이 방법으로 루우핀콩의 두꺼운 외피가 균체 성장을 저해하고 있음을 발견하였다.

• 멤브레인
• /
• 제23권5호
• /
• pp.367-374
• /
• 2013

본 논문에서는 Pebax-2533 판형 분리막을 1-프로판올과 n-부탄올 혼합용매를 이용하여 용해, 건조하여 제조하였고 time-lag 장치를 이용하여 $CO_2$, $N_2$ 투과특성을 평가하였다. 제조된 분리막은 평가조건에 따라서 130-288 barrer의 $CO_2$ 투과율을 가졌으며, $CO_2/N_2$ 투과선택도는 5-8이었다. Time-lag 장치의 주입부 압력이 증가함에 따라서, 투과온도가 낮아짐에 따라서, 그리고 혼합용매의 n-부탄올 양이 증가함에 따라서 $CO_2$ 투과도는 감소하였다. 이러한 실험 자료는 Pebax-2533 분리막의 $CO_2$ 투과율이 $CO_2$ 용해에 매우 의존할 것이라 예측과 달리, $CO_2$ 용해뿐만 아니라 $CO_2$ 확산도 매우 중요한 단계임을 의미하였다.

• Journal of Mechanical Science and Technology
• /
• 제16권2호
• /
• pp.155-164
• /
• 2002

The power steering system for vehicles is becoming essential for supporting the steering efforts of the drivers, especially for the parking lot maneuver Although hydraulic power steering has been widely used for years, its efficiency is not high enough. The problems associated with a hydraulic howe. steering system can be solved by a motor driven power steering (MDPS) system. In this study, a dynamic model and a control algorithm for the ball screw type of MDPS system have been derived and analyzed by using the method of discrete modeling technology. To improve steering feel and power steering characteristics, two derivative gains are added to the conventional power boosting control algorithm. Through simulations, the effects of the control gain on the steering angle gain were verified in the frequency domain. The steering returnability and steering torque phase lag in on-center handling test were also evaluated in the time domain.

• 한국생산제조학회지
• /
• 제6권3호
• /
• pp.58-64
• /
• 1997

A micromechanics model to describe the elastic behavior of fiber or whisker reinforced metal matrix composites was developed and the stress concentrations between reinforcements were investigated using the modified shear lag model with the comparison of finite element analysis (FEA). The rationale is based on the replacement of the matrix between fiber ends with the fictitious fiber to maintain the compatibility of displacement and traction. It was found that the new model gives a good agreement with FEA results in the small fiber aspect ratio regime as well as that in the large fiber aspect ratio regime. By the calculation of the present model, stress concentration factor in the matrix and the composite elastic modulus were predicted accurately. Some important factors affecting stress concentrations, such as fiber volume fraction, fiber aspect ratio, end gap size, and modulus ratio, were also discussed.

• 한국기술혁신학회:학술대회논문집
• /
• 한국기술혁신학회 2000년도 추계 학술대회(The 2000 Autumn Conference of korea Technology Inovation Society)(한국기술혁신학회)
• /
• pp.346-356
• /
• 2000

This paper aims to analyse the relationship between R＆D investment and economic growth in Korea. The analysis result shows 38 percent of average economic growth rate(7.1%) of Korea between 1976 and 1998 was achieved by the growth of Total Factor Productivity (TFP), and the R&D investment during the period contributed in achieving the economic growth rate by as much as 9.86 percent. In the process of the estimate, the rate of return of the R&D investment from both government and private was calculated as 47 percent. The relationship between private R&D investment, government R&D investment and the GDP was also investigated, and it was estimated that the private sector invested 2.0 percent of the GDP in R&D during the period, and was found that 1 won of government R&D investment induced 0.202 won of private sector's R&D investment. However, the time-lag effect, which is naturally believed to exist between the R&D investment and the economic growth, could not be analysed in a mathematical form, because of the lack of the data to establish this relationship. However, this paper believe that the time-lag effect in this relationship was included implicitly by using the data of 23 years.

• International Journal of Concrete Structures and Materials
• /
• 제3권1호
• /
• pp.33-37
• /
• 2009

Fiber Bragg grating (FBG) sensors already have been the focus for structural health monitoring (SHM) due to their distinguishing advantages. However, as bare optical fiber is very fragile, bare FBG strain sensor without encapsulation can not properly be applied in practical infrastructures. Therefore encapsulation techniques for making encapsulated FBG strain sensor show very important in pushing forward the application of FBG strain sensors in SHM. In this paper, a simplified approximate method to analyze the stress transferring rules for embedded FBG strain sensors in concrete monitoring is put forward according to mechanics of composite materials. Shear lag theory is applied to analyze the stress transferring rule of embedded FBG strain sensor in measured host material at the first time. The measured host objects (concrete) and the encapsulated FBG strain sensor are regarded as a composite, and then the stress transfer formula and stress transfer coefficient of encapsulated FBG strain sensor are obtained.

• 한국군사과학기술학회지
• /
• 제3권2호
• /
• pp.121-130
• /
• 2000

A practical method is proposed to improve hit probability of the digital gun fire control system, when the measured rate of the tracking sensor becomes biased under some operational situation. For ground moving target it is shown that the well-known Kalman filter which uses position measurement only can be optimally used to eliminate the rate bias error. On the other hand, for 3D moving aircraft we present a new algorithm which incorporate FIR-type filter, which uses position and rate measurement at the same time, and the fixed-lag smoother using position measurement only, and show that it has the optimal performance in terms of both estimation accuracy and response time.

• Macromolecular Research
• /
• 제10권5호
• /
• pp.246-252
• /
• 2002

In order to the development of the delivery device of long-acting local anesthetics for postoperative analgesia and control of chronic pain of cancer patient, fentnyl-loaded poly (L-lactide-co-glycolido) (PLGA, molecular weight, 5,000 g/mole; 50 : 50 mole ratio by lactide to glycolide) microspheres (FMS) were studied. FMS were prepared by an emulsion solvent-evaporation method. The influence of several preparation parameters such as initial drug loading, PLGA concentration, emulsifier concentration, oil phase volume, and fabrication temperature has been investigated on the fentanyl release profiles. Generally, the drug showed the biphasic release patterns, with an initial diffusion followed by a lag period before the onset of the degradation phase, but there was no lag time in our system. Fentanyl was slowly released from FMS over 10 days in vitro with a quasi-zero order property. The release rate increased with increasing drug loading as well as decreasing polymer concentration with relatively small initial burst effect. From the results, FMS may be a good formulation to deliver the anesthetic for the treatment of chronic pain.

• Journal of Animal Science and Technology
• /
• 제62권1호
• /
• pp.74-83
• /
• 2020

Organic waste used as a feedstock in the anaerobic digestion (AD), it includes carbon and nitrogen. Carbon and nitrogen have an effect on the various digestive characteristics during AD, however, the study is rare about those of the interaction. This study investigates the influence of carbon type and carbon to nitrogens (C/N ratios) on the AD characteristics of organic waste. Experimental treatments involved a combination of three carbon types with three C/N ratios. The AD tests were carried out using a 125-mL serum bottle at a constant temperature of 37℃ and moisture 95% for 18 days. Degradation pattern shows the difference among three-carbon treatments, the starch group was faster than other groups. Maximum methane production date was similar between starch (9.96 ± 0.05 day) and xylan group (10.0 ± 0.52 day), those of the cellulose group (14.6 ± 1.80 day) was slower than other groups (p < 0.05). The lag phase was only affected by the carbon type (p < 0.05). Ammonia nitrogen was mainly affected by nitrogen concentration regardless of carbon type (p < 0.05). This study showed that xylan is useful as feedstock in order to decrease the lag phase, and it showed that ammonia was independently affected by the nitrogen concentration.

• Journal of Pharmaceutical Investigation
• /
• 제33권3호
• /
• pp.157-162
• /
• 2003

The feasibility of [P(AA-co-PEGMM)] film as a buccal mucoadhesive patch was previously reported by estimating mucoadhesiveness and release characteristics. To find a rational penetration enhancer of [P(AA-co-PEGMM)] film containing butorphanol tartrate (Bt), penetration of Bt from [P(AA-co-PEGMM)] film which contained various additives was estimated by measuring its flux, Papp and lag tme in in vitro buccal membrane of porcine. EDTA showed almost no increase of Bt permeability, wherease SGC, STDHF and SLS increased the permeability of Bt with the order of SGC > STDHF > SLS. The rational additive concentration of SGC was 4% and its Papp and lag time were $1.93{\times}10^{-4}{\pm}4.21{\times}10^{-6},\;126.60{\pm}21.88min\;(control\;:\;Papp\;0.45{\times}10^{-4};\;lag\;time\;211.01{\pm}16.77\;min)$, respectively.