• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7149-7152
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• 2014

A large number of epidemiological studies have demonstrated that obesity is a risk factor for several human cancers. Several animal studies using rodents with diet-induced or genetic obesity have also demonstrated that obesity can promote tumor development. However, the effects of obesity on the early stages of carcinogenesis, and especially on the spontaneous occurrence of somatic gene mutations, remain unclear. To investigate the effects of obesity on the rate of spontaneous gene mutations, we performed reporter gene mutation assays in liver, kidney, and colon, organs in which obesity appears to be associated with cancer development on the basis of epidemiological or animal studies, in mice with high fat diet (HFD)-induced obesity. Six-week-old male and female C57BL/6 gpt delta mice were fed HFD or standard diet (STD) for 13 or 26 weeks. At the end of the experiments, reporter gene mutation assays of liver, kidney, and colon were performed. Final body weights and serum leptin levels of male and female mice fed HFD for 13 or 26 weeks were significantly increased compared with corresponding STD-fed groups. Reporter gene mutation assays of liver, kidney, and colon revealed that there were no significant differences in gpt or $Spi^-$ mutant frequencies between STD- and HFD-fed mice in either the 13-week or 26-week groups. These results indicate that HFD treatment and consequent obesity does not appear to influence the spontaneous occurrence of somatic gene mutations.

• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.15 no.1
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• pp.37-42
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• 2004

Electrolarynx(EL), battery operated vibrators which are held against the neck by on-off button, has been widely used as a verbal communication method among post-laryngectomized patients. EL speech can produce easily without need of any additional surgery or special training and be used with any other methods. This institute developed a neck-typed EL named "Blueton" in commperation with EL Company Linkus, which consists of 3 parts : Vibrator part, Control part, Battery part. In this study we evaluated the acoustic characteristics of the produced voices by Blueton compared with Servox-inton using MDVP. Three EL users (2 full time users, 1 part time user) were participated. The results revelaed that NHR higher in Servox than Blueton and intensity is higher in Blueton than Servox. The spectra for vowels produced by EL speakers are mixed signals combined with talkers' vocal output and electrolarynx noise. The spectra pattern is similar with two ELs. High, SPI index and vowel spectra from MDVP demonstrated characteristics of both electrolarynxes related to noise signal. This finding suggests that Blueton helps to provide one of useful rehabilitation options in the post laryngectomy patients.

• Proceedings of the Korea Water Resources Association Conference
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• 2012.05a
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• pp.446-446
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• 2012

농업은 다른 산업과 달리 원천적으로 기후 조건과 변화에 크게 좌우되는 분야로, 기후변화로 인한 영향에 가장 민감한 분야라고 할 수 있다. 안정적이고 지속적인 작물 생산을 위해서는 기후변화가 농업수자원에 미치는 영향에 대하여 정확히 파악하고, 이로 인해 발생할 수 있는 부정적 효과를 최소화하기 위한 연구가 필요하다. 특히 기온 상승, 강수량 및 강우강도 변화, 증발산량 및 일조시간 변화 등의 기후변화는 우리나라의 가뭄 발생의 양상에도 변화를 야기하게 될 것이다. 따라서 현 상황을 바탕으로 미래에 발생할 가뭄에 대하여 예측하고, 그 취약성을 줄이기 위한 합리적인 계획이 필요하다. 즉 기후변화에 대처하기 위해서는 향후 발생할 수 있는 가뭄의 특성을 파악하여 미래 수자원 관리에 활용하기 위한 가뭄특성 분석이 필요하다. 가뭄은 기상학적 가뭄, 기후학적 가뭄, 농업적 가뭄, 대기학적 가뭄, 수문학적 가뭄, 사회경제적 가뭄 등으로 구분할 수 있는데, 일반적으로 강우량 등의 기상조건을 분석하는 방법에서부터 저수량과 유역 유출량, 그리고 토양수분 등의 수문학적 조건들로 가뭄을 분석하는 방법들까지 매우 다양하다. 가뭄의 정량화는 가뭄을 표현하는 대상의 특성에 따라 평가방법이 달라질 수 있다. 가뭄의 경향이나 그 정도를 파악하기 위해서는 하나의 가뭄 지수가 아닌 다양한 항목을 바탕으로 평가가 이루어져 한다. 현재 기후변화와 관련한 가뭄 연구에 있어서 기상학적 가뭄지수인 SPI (Standardized Precipitation Index) 중심으로 많은 연구 이루어졌을 뿐, 농업적 가뭄지수를 바탕으로 한 연구는 이루어지지 않고 있다. 따라서 본 연구에서는 기후변화에 따른 우리나라의 농업가뭄 특성을 분석하기 위하여 토양수분지수 (Soil Moisture Index)를 이용하여 중권역별 가뭄 평가하고 그 변화를 분석하였다. 본 연구를 위하여 이를 위하여 CGCM3.1 (Coupled Global Climate Model Ver. 3.1) 및 LARS-WG (Long Ashton Research Station Weather Generator)를 이용하여 2011년부터 2100년까지의 A1B, A2 및 B1 시나리오별로 기상자료를 생성하고, 이를 바탕으로 SMI 지수를 산정하여 유역별 가뭄 발생 빈도 및 심도를 시나리오별로 분석하였다. 본 연구 결과는 향후 기후변화로 인한 농업가뭄 발생의 양상 및 특성을 파악하고 전망함으로써, 추후 발생할 수 있는 부정적 효과를 최소화하기 위한 대응 전략 및 농업수자원 정책의 기초 자료로 활용될 수 있을 것으로 판단된다.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.311-311
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• 2018

Generally, the water resources in South Korea were supplied from river flow and dam. Among them, the dam is the most important supplier for the residential and industrial water. However, the climate change has caused a setback in water supply chain. The objective of the study is therefore to suggest a drought index consideing dam water shortage for efficiently dam and water resources management. The standardzied balanced index(SBI), which has same concept with the standardzied precipitation index, were suggested. Also, the management index for the dam were established with SSVI and the storage percentage that compared to previous years.

• Journal of Korea Water Resources Association
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• v.57 no.7
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• pp.481-491
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• 2024

Recent droughts make hydroelectric power generation (HPG) decreasing. Due to climate change in the future, the frequency and intensity of drought are expected to increase, which will increase uncertainty of HPG in multi-purpose dams. Therefore, it is necessary to estimate the amount of HPG according to climate change scenarios and analyze the effect of drought on the amount of HPG. This study analyzed the future HPG of the Soyanggang Dam and Chungju Dam according to the SSP2-4.5 and SSP5-8.5 scenarios. Regression equations for HPG were developed based on the observed data of power generation discharge and HPG in the past provided by My Water, and future HPGs were estimated according to the SSP scenarios. The effect of drought on the amount of HPG was investigated based on the drought severity calculated using the standardized precipitation index (SPI). In this study, the future SPIs were calculated using precipitation data based on four GCM models (CanESM5, ACCESS-ESM1-5, INM-CM4-8, IPSL-CM6A) provided through the environmental big data platform. Overall results show that climate change had significant effects on the amount of HPG. In the case of Soyanggang Dam, the amount of HPG decreased in the SSP2-4.5 and SSP5-8.5 scenarios. Under the SSP2-4.5 scenario the CanESM model showed a 65% reduction in 2031, and under the SSP5-8.5 scenario the ACCESS-ESM1-5 model showed a 54% reduction in 2029. In the case of Chungju Dam, under the SSP2-4.5 and SSP5-8.5 scenarios the average monthly HPG compared to the reference period showed a decreasing trend except for INM-CM4 model.

• Korean Journal of Food Science and Technology
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• v.24 no.4
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• pp.311-314
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• 1992

Several Physico-chemical properties of the retentate obtained from reverse osmosis of soybean curd whey were studied. The contents of sucrose, raffinose and stachyose in the retentate were 32.59%d.b., 4.76%d.b. and 9.99%d.b., respectively. Potassium (5.23%d.b.), in the retentate was a dominant element in ash. Protein content (18.69%d.b.), amino acid composition and subunit pattern of protein in PAG-electrophoresis were somewhat different from those of the soybean protein. Emulsification activity, emulsification stability and viscosity of protein isolated from soybean curd whey (WPI) were slightly inferior compared to protein isolated from soybean (SPI), with the exception of solubility that depended on the pH of WPI.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2003.10a
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• pp.661-664
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• 2003

Trade-off of sorority and speed always exists in the latest network environment. Recently, developed security processors is improved very performance, and sorority connection algorithms of a lot of part were embodied by hardware. This high speed security processor is essential ingredient in string network security solution equipment development that require very big band width. In this paper, we wish to describe about design and implementation of 10 Giga VPN equipments. In this system, embodied 10 Giga to use Cavium company's Nitrox-II processor, and supports two SP14-2 interface and PCI interface. All of the password algorithm that password algorithm that support is used in common use VPN equipment for compatibility with common use VPN equipment are supported and support SEED algorithm developed in domestic. Designed to support IPsec and SSL protocol, and supports all of In-Line structure that is profitable in high speed transaction and the Look-Aside structure that is profitable in practical use degree of NPU(Network Processor Unit).

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.274-277
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• 2006

The EAC(Estimate at Completion) among existing methods, which estimate cost and time effectively, help managers anticipate changeable several results at the point of $15{\sim}30%$ in the project progress. However, this method may cause such some problems as not to consider the periodically changing circumstances caused by construction risks or uncertainties which can affect the cost and time in the project, and to regard collected and accumulated data only as a single value when predicting the results on the progress. Accordingly, it is very difficult to accept the even small range of variability based on the anticipation of EAC. Consequently, the study focuses on the possibility methodology to anticipate time and cost accurately on the way to utilize EVMS(Earned Value Management System), and also suggest the way to perform the right estimation of EAC as considering various risks and uncertainties in construction projects.

• International Journal of Highway Engineering
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• v.10 no.3
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• pp.221-230
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• 2008

In Korea, Expressway and National Highway System has been continually managed by their own pavement management system. The pavement condition evaluation system has not been developed for the municipal roads except for Seoul city. Therefore, this study focuses on analyzing the characteristics of distress in major city's pavement and developing the pavement condition index for the municipal PMS. Panel rating and pavement condition survey for the selected pavement sections were conducted for developing pavement condition index. Municipal level pavement condition index(MPCI) was developed by statistical analysis. Also, a sensitivity analysis for each independent variable of the MPCI and comparison with other pavement condition indicies, such as SPI and HPCI, were performed.

• Applied Biological Chemistry
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• v.41 no.5
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• pp.349-354
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• 1998

The protease produced by Bacillus subtilis YG-95 was purified by precipitating with ammonium sulfate, DEAE-sepharose 6B and Sephadex G-100 column chromatogtaphies and its purified enzymological characteritics were investigated. The molecular weight of purified protease was estimated about 43kilodalton by SDS PAGE The optimum pH and temperature for the purified protease activity were pH 10.0 and $55^{\circ}C$, respectively. The enzyme was stable in broad range of pH 5.0 to 12.0. and at the below $45^{\circ}C$. The purified enzyme activty was inhibited by $Fe^{3+}$ and $Al^{3+}$. The activity was significantly inhibited more than 80% by O-Phenanthroline, PMSF and SDS. The $K_m$ value of the purified enzyme against Soy Protein Isolate as a substrate was 1.28 mg/ml.