• 한국건설관리학회논문집
• /
• 제14권2호
• /
• pp.22-34
• /
• 2013

최근 건설 프로젝트가 대형화, 복잡화, 전문화되면서 다양한 참여자들 사이에서 발생하는 방대한 양의 정보 활용이 중요해지고 있다. 특히 이러한 정보는 건설프로젝트에서 주도적인 역할을 담당하는 건설현장에서 주로 생산된다. 건설현장 관련 참여자 간 정보 교환의 미흡은 공기지연, 품질하자와 같은 건설생산성 저해 요인을 유발한다. 이러한 문제점을 해결하기 위하여 건축물의 전 생애주기 동안에 필요한 데이터를 생산하고 관리하는 프로세스인 BIM(Building Information Modeling)에 대한 관심이 높아지고 있다. 그러나 국내에서 BIM의 도입은 주로 설계단계에 집중되어 있으며 시공단계에서 BIM의 활용정도는 미비한 실정이다. 따라서 본 연구는 선행연구 고찰을 통하여 골조공사에서 정보 교환의 미비로 인한 실패요인을 구분하고, BIM의 적용이 가능한 업무를 전문가 면담조사를 통하여 도출할 것이다. 그리고 BIM이 도입된 다수의 골조공사 현장의 분석을 통해 업무별 BIM 지원을 위한 참여자간 정보의 흐름을 실무 수준으로 제안하고 이에 따른 기대효과를 제시하는데 본 연구의 목적이 있다.

• Earthquakes and Structures
• /
• 제2권4호
• /
• pp.357-376
• /
• 2011

Ground motion models predict the mean and standard deviation of the logarithm of spectral acceleration, as a function of predictor variables such as earthquake magnitude, distance and site condition. Such models have been developed for a variety of seismic environments throughout the world. Some calculations, such as the Conditional Mean Spectrum calculation, use this information but additionally require knowledge of correlation coefficients between logarithmic spectral acceleration values at multiple periods. Such correlation predictions have, to date, been developed primarily from data recorded in the Western United States from active shallow crustal earthquakes. This paper describes results from a study of spectral acceleration correlations from Japanese earthquake ground motion data that includes both crustal and subduction zone earthquakes. Comparisons are made between estimated correlations for Japanese response spectral ordinates and correlation estimates developed from Western United States ground motion data. The effect of ground motion model, earthquake source mechanism, seismic zone, site conditions, and source to site distance on estimated correlations is evaluated and discussed. Confidence intervals on these correlation estimates are introduced, to aid in identifying statistically significant differences in correlations among the factors considered. Observed general trends in correlation are similar to previous studies, with the exception of correlation of spectral accelerations between orthogonal components, which is seen to be higher here than previously observed. Some differences in correlations between earthquake source zones and earthquake mechanisms are observed, and so tables of correlations coefficients for each specific case are provided.

• 한국생물공학회:학술대회논문집
• /
• 한국생물공학회 2001년도 추계학술발표대회
• /
• pp.827-828
• /
• 2001

이 실험은 특정 DNA를 검출 할 수 있는 새로운 방법을 제시하고 개발하려는 것이다. 이것은 geno-chromatography 분석방법이라고 하여 DNA capture probe를 membrane상에 고정하고 PCR을 통하여 증폭된 특정 유전자를 hybridization 반응을 이용하여 탐지하는 것이다. 이러한 개념을 식중독균의 일종인 Salmonella 균의 탐지에 적용하여 그 분석시스템의 성능을 확인 할 수 있었다.

• Journal of Microbiology and Biotechnology
• /
• 제28권5호
• /
• pp.826-830
• /
• 2018

A Cre/loxP-${\delta}$-integration system was developed to allow sequential and simultaneous integration of a multiple gene expression cassette in Saccharomyces cerevisiae. To allow repeated integrations, the reusable Candida glabrata MARKER (CgMARKER) carrying loxP sequences was used, and the integrated CgMARKER was efficiently removed by inducing Cre recombinase. The XYLP and XYLB genes encoding endoxylanase and ${\beta}$-xylosidase, respectively, were used as model genes for xylan metabolism in this system, and the copy number of these genes was increased to 15.8 and 16.9 copies/cell, respectively, by repeated integration. This integration system is a promising approach for the easy construction of yeast strains with enhanced metabolic pathways through multicopy gene expression.

• Molecules and Cells
• /
• 제41권1호
• /
• pp.11-17
• /
• 2018

Autophagy is critical for the maintenance of organelle function and intracellular nutrient environment. Autophagy is also involved in systemic metabolic homeostasis, and its dysregulation can lead to or accelerate the development of metabolic disorders. While the role of autophagy in the global metabolism of model organisms has been investigated mostly using site-specific genetic knockout technology, the impact of dysregulated autophagy on systemic metabolism has been unclear. Here, we review recent papers showing the role of autophagy in systemic metabolism and in the development of metabolic disorders. Also included are data suggesting the role of autophagy in human-type diabetes, which are different in several key aspects from murine models of diabetes. The results shown here support the view that autophagy modulation could be a new modality for the treatment of metabolic syndrome associated with lipid overload and human-type diabetes.

• 한국건축시공학회:학술대회논문집
• /
• 한국건축시공학회 2017년도 춘계 학술논문 발표대회
• /
• pp.152-153
• /
• 2017

In the construction site, it is necessary to estimate the compressive strength of concrete in order to adjust the demolding time of the form, and establish and adjust the construction schedule. The compressive strength of concrete is determined by various influencing factors. However, the conventional method for estimating the compressive strength of concrete has been suggested by considering only 1 to 3 specific influential factors as variables. In this study, six influential factors (Water, Cement, Fly ash, Blast furnace slag, Curing temperature, and humidity) of papers opened for 10 years were collected at three conferences in order to know the various correlations among data and the tendency of data. After using algorithm of various methods of machine learning techniques, we selected the most suitable regression analysis model for estimating the compressive strength.

• 한국정밀공학회:학술대회논문집
• /
• 한국정밀공학회 2006년도 춘계학술대회 논문집
• /
• pp.621-622
• /
• 2006

In this paper, we performed the customization of CAE analysis in the process of product development and verification. The purpose of customized analysis is to implement collaboration framework of inter-corporate, inter-division for knowledge process based on product development. Customized analysis methodology using ANSYS Workbench API is presented for the web-based and workbench-based application. Cellular phone was selected as a CAD model, and template based process of analysis is conducted. By using this system, customized analysis is suitable to site or user oriented specific analysis and for user who has little experience on CAE analysis.

• 한국병원경영학회지
• /
• 제14권2호
• /
• pp.41-59
• /
• 2009

Modern job seekers often visit recruitment web-site for employment. Recruiting on the Internet is one of the fastest-growing recruitment methods. But there was not research about Internet recruitment in health care labor market. The purpose of this study is to research the actual conditions of hospital recruitment by using internet homepage of Korea College of Hospital Administrators(KCHA). Data were collected from 399 iob posting and job seeker's interest in Internet homepage of KCHA. This study analyzed the research model using data mining method. This study shows that the frequency of job posting and job seeker's interest depend upon a season. The result of this study indicates that there is necessity to present the various and specific employment conditions. As the recruitment becomes job seeker-centered in other industry labor market, it is also recommended in the health labor market. Therefore a job posting should provide a salary range and emphasize competitive benefits for job seekers in the health labor market.

• 한국전산구조공학회:학술대회논문집
• /
• 한국전산구조공학회 2003년도 가을 학술발표회 논문집
• /
• pp.495-502
• /
• 2003

This study proposed the Probability Density Function (PDF) interpolation technique to evaluate the seismic fragility curves as a function of the return period. Seismic fragility curves have been developed as a function of seismic intensities such as peak ground acceleration, peak pound velocity, and pseudo-velocity spectrum. The return period of design earthquakes, however, can be more useful among those seismic intensity measurements, because the seismic hazard curves are generally represented with a return period of design earthquakes and the seismic design codes also require to consider the return period of design earthquake spectrum for a specific site. In this respect the PDF interpolation technique is proposed to evaluate the seismic fragility curves as a function of return period. Seismic fragility curves based on the return period are compared with ones based on the peak ground acceleration for the bridge model.

• Wind and Structures
• /
• 제32권5호
• /
• pp.501-508
• /
• 2021

The turbine industry demands a reliable design with affordable cost. As technological advances begin to support turbines of huge sizes, and the increasing importance of wind turbines from day to day make design safety conditions more important. Wind turbines are exposed to environmental conditions that can affect their installation, durability, and operation. International Electrotechnical Commission (IEC) 61400-1 design load cases consist of analyses involving wind turbine operating conditions. This design load cases (DLC) is important for determining fatigue loads (i.e., forces and moments) that occur as a result of expected conditions throughout the life of the machine. With the help of FAST (Fatigue, Aerodynamics, Structures, and Turbulence), an open source software, the NREL 5MW land base wind turbine model was used. IEC 61400-1 wind turbine design standard procedures assessed turbine behavior and fatigue damage to the tower base of dynamic loads in different design conditions. Real characteristic wind speed distribution and multi-directional effect specific to the site were taken into consideration. The effect of these conditions on the economic service life of the turbine has been studied.