• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.1
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• pp.39-49
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• 2007

Rheumatoid arthritis is an autoimmune disease involving multiple joint. In order to access the suppressive effects of JTT on rheumatoid arthritis and it's effects on immune system we investigated whether JTT could suppress the disease progression of collagen-induced arthritis. DBA/1 mice were immunized with bovine type II collagen. After a second collagen immunization, mice were treated with DW, JTT (200 or 400 mg/kg) or methotrexate (MTX, 30 mg/kg) as a positive control. Oral administration of JTT significantly suppressed the progression of CIA, which extend is comparable to that of MTX. Histological examination reveled that JTT inhibited infiltration of inflammatory cells into affected paw joint and bone erosion and cartilage destruction were greatly reduced compared with control. Total cell number of spleen, lymph node and peripheral blood were significantly reduced. The absolute number of CD19$^+$, CD3$^+$/CD69$^+$, CD4$^+$/CD25$^+$ cell in spleen from JTT treated mice were significantly decreased. The absolute number of CD19$^+$, CD3$^+$, CD3$^+$/CD69$^+$, CD4$^+$, CD4$^+$/CD25$^+$ CD8$^+$, CD49b, CD3/CD49b cells in draining lymph node were significantly increased compared with control. In peripheral blood mononuclear cells of JTT treated mice, the absolute number of CD4$^+$, CD4$^+$/CD25$^+$, CD3$^+$/CD69$^+$ cells were significantly decreased compared with control, while that of CD49b$^+$ was slightly increased. Infiltration of CD3$^+$ cells and CD11b$^+$/Gr-1$^+$ cells into paw joint was significantly reduced in JTT treated mice. The levels of pathologic cytokines including TNF-a and IL-6 in serum were significantly decreased by oral treatment with JTT The levels of IFN-g in the culture supernatant of splenocyte stimulated with CD3$^+$/CD28$^+$ or collagen were dramatically decreased, while the levels of IL-4 was increased under CD3$^+$/CD28$^+$ or collagen stimulation. Rheumatoid factors including IgG, IgM and collagen specific antibody were present much lower in the serum of JTT treated mice than control. Taken together, JTT has suppressive effects on rheumatoid arthritis by modulating immune system, and has potential to use anti-rheumatic arthritic agent in human.

• Journal of Embryo Transfer
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• v.22 no.2
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• pp.81-87
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• 2007

The purpose of the present study was to determine the preventive effects of the two antioxidant vitamin E and catechin on DEHP-induced disturbance of spermatogenesis in male rats. Rats at 4 weeks of age were randomly allocated into five groups with 20 animals per group. The first group was not any administrated as control. The second group was administrated DEHP (2 g/kg) daily for 14 days. The third group was administrated vitamin E (500 IU/kg) following DEHP treatment by the same method (daily for 14 days). The fourth group was administrated catechin (200 mg/kg) following DEHP treatment by the same method. The fifth group was co-administrated vitamin E (500 IU/kg) and catechin (200 mg/kg) following DEHP treatment by the same method. In order to determine the preventive effects, we examined pathological changes of testis with apoptotic index, and characteristics of sperm with computer assisted sperm analysis (CASA). Vitamin E and catechin supplementation were significantly prevented the testicular atrophy, apoptosis of germ cells in the seminiferous tubules and abnormal rate of sperm. Moreover, sperm concentration, viability and motility was significantly recovered in groups of alone and along with vitamin E and catechin. The results suggest that preventive effects of alone and along administration of vitamin E and catechin on DEHP-induced testicular atrophy damages have been demonstrated.

• Journal of the Korean Society of Radiology
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• v.7 no.6
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• pp.427-431
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• 2013

The purpose of this study in the patient suffering from scoliosis analyse the degree of scoliosis, Cobb's angle, by Yoga exercise therapy and then find the effects of Yoga program on idiopathic scoliosis. In this study, yoga program restores flexibility and elasticity by relaxing and contracting muscles around vertebrea. It could help scoliosis from balancing agonistic muscle, antagonistic muscle and synergistic muscle during exercise. so did pelvis movement and vertebral twisting movement. The subject for this experiment was a meddle school girl diagnosed with scoliosis in C hospital in Gwang-ju city. In order to find the effects of yoga program on idiopathic scoliosis, conducted yoga program 60minutes a day, 5days a week for 12weeks. Before and after experiment, measured Cobb's angle by radiation and verified effects. First, master of yoga and chiropractor studied and made movement together. Second, Yoga program-developed about scoliosis was prescribed for the meddle school girl suffering from scoliosis during 12weeks. Third, Feasibility and effect was verified on idiopathic scoliosis by yoga program. As a result, the amount of curvature was reduced about 5degrees than before and improved the idiopathic scoliosis. Lots of Yoga movements help patients of idiopathic scoliosis to be improved. It shows that Yoga program could give adolescent scoliosis a hand.

• The Journal of Korean Physical Therapy
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• v.13 no.3
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• pp.551-559
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• 2001

The purpose of this study is to investigate the effects of the practice exercising and cycling on the gait abilities of dementia elderly patients. Forty forty elderly patients with dementia were participants. Participants were divided into three groups as A, B, and C, Group A was a standard group which had been treated with electric treatment, hot pack, and exercise. The second group B had been treated with cycling added to the treatments of group A. Finally, treatments of group C were arranged by subtraction of exercise from those of group A. The test was a 'timed up and go test' used for measuring the rates of the gait ability through four months. The gait ability of each group was measured after each month. The results of this study are as following: 1. After first month, the averages of changes in gait ability of group C, A and B were -1.69, -1.67, and -1.13 seconds respectively. That means that dementia control was achieved significantly in group A and B (p<0.05)whereas it was not in group C. 2. The averages after two months were -4.00 seconds for group C, -2.60 seconds for group A, and -1.56 seconds for B, respectively. All groups acquired significant effects in treating dementia (p<0.05). 3. After three months, -6.38, -3.00 and -2.31 seconds were average values of group C, A and B respectively. Same as results after two months, there were significant effects in all groups (p<0.05). 4. After four months, the averages of changes in gait ability of three groups were -8.00. -3.93 and -3.00 seconds for group C, A and B respectively. In the all patients treated analysis, treatments showed significant results (p<0.05). 5. Compared with each other through four months. three groups testing the timed up and go test showed more efficient in maintaining gait ability, in order of group B. A, and C

• Journal of Animal Science and Technology
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• v.60 no.4
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• pp.9.1-9.11
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• 2018

Background: In recent years, with the prohibition of antibiotics used as growth stimulants in the nutrition of farm animals, researchers have searched for alternative natural and reliable products in order to be able to sustain the developments experienced during the use of antibiotics and to overcome the possible inconveniences. In this context, studies on evaluation of essential oils in poultry nutrition have been reported to improve the utilization of feed, stimulate the release of digestive enzymes, increase absorption in the stomach and intestines, antimicrobial and anti-parasitic effects and thus, can be an alternative to antibiotics and improve meat quality as well. Indeed, this study has been carried out to explore the effects of the addition of 150 mg/kg capsicum oleoresin (CAP), carvacrol (CAR), cinnamaldehyde (CIN) or their mixture (CAP+CAR+CIN) into the broilers' ration over sensory, physical and chemical properties in breast meat and leg meat. Methods: Experiments were conducted over 400 male and female broiler chicks (Ross-308) in 5 groups (1 control group and 4 treatment groups), each composed of 80 chicks. The control group was fed without feed additives while the second, third, fourth and the fifth groups were fed with 150 mg CAP/kg feed, 150 mg CAR/kg feed, 150 mg CIN/kg feed, and 150 mg CAP+CAR+CIN/kg feed, respectively. Results: Addition of CAP, CAR, CIN or CAP+CAR+CIN had effects on the sensory (of taste, tenderness, juiciness and overall acceptability); physical properties (of $L^*$ value and toughness), the chemical properties (of DM, CF, CP, linoleic, EPA, behenic, MUFA, PUFA and ${\Sigma}n-6$ of the leg meat), the physical characteristics (of toughness and firmness), and the chemical properties (of CF, CP, linoleic, ecosenic, EPA, lignoseric, MUFA and ${\Sigma}n-3$) of the breast meat in comparison to control group. Furthermore, while the treatments had positive impacts on thawing loss, cooking loss and water holding capacity in both breast and leg meat; no effect was observed on pH value and lipid oxidation on day 1, day 4 and day 8. Conclusion: The results strongly suggested that the addition of CAP, CAR, CIN or CAP+CAR+CIN to the rations of the broiler chicks changed the sensory, physical and chemical properties of breast and leg meat. It was also observed that these compounds were more effective when they were added to the ratio as a mixture rather than adding them individually.

• Journal of Labour Economics
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• v.24 no.1
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• pp.97-124
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• 2001

Co-residence is a type of intergenerational private transfers of resources: money, time and space. Adult daughters and their elderly parents decide to co-reside, depending on their utility levels before and after co-residence that mainly depend on the health status of the elderly. Therefore, co-residence implies positive net benefits to both parties in the sense that, when they co-reside, elderly parents share childcare and adult daughter provide elderly care. In other words, formal (paid) care can be substituted with informal (unpaid) one. Both marriage and giving births are considered as the major obstacles to labor market attachment of women who bear burdens of home production and childcare. Co-residence can be a solution for married women to avoid career interruption by sharing burdens with their elderly parents. However, most previous studies using the U.S. data on intergenerational private transfers focused on elderly care and have concluded that they reduce government expenditures associated with public subsidies to the elderly. This study focuses on adult daughters and it examines effects of co-residence on labor supply of married women in Korea, who face limited formal childcare programs in terms of both quantity and quality. It applies the Tobit model of married women's labor supply to the data from the Second Wave of the Korean Labor and Income Panel Survey( 1999), in order to investigate effects of co-residence and the work and health status of the co-residing elderly as well as their own health status. Four specifications of the empirical model are tested that each includes co-residence with elderly parents, their gender, or their work and health status. Estimation results show that co-residence, co-residence with female elderly, and co-residence with not-working female elderly have significant positive effects on labor supply of married women while poor health status of co-residing female elderly does not bring about any negative effects. However, co-residence with male elderly, regardless of their work and health status, has no significant effect The results indicate that co-residence is closely related to sharing of home production among female elderly and adult daughters who are married and, through intergenerational private transfers of resources in terms of time, it helps women avoid career interruption.

• Korean Security Journal
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• no.37
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• pp.269-293
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• 2013

Raising the level of quality of the security industry is an urgent matter. Since security service is provided through direct contact with customers, the security agents' expression of emotion directly influences the evaluation of the security company or their own earnings. So emotion control at customers demand is necessary above all things, and this research established what difference the service career makes in the influence that the security agent's emotional labor exerts on customer orientation, and the results of the analysis are summarized as follows. First, the security agent's emotional labor exerted negative effects on customer orientation. From this, the conclusion that the higher the security agent's emotional labor, the lower the customer orientation, was obtained. Second, the service career showed differences in the effects of the security agent's emotional labor on the customer orientation. In other words, the conclusion that the lower the security agent's service career, the greater effects the emotional labor exerts on the customer orientation, was obtained. In conclusion, in order to raise the level of customer service, systematic education to control the emotional labor of the security agents with low service career is necessary. Particularly, since the emotional labor of new employees is related to the service environment, the improvement of the service environment of the security agents is more important than anything else.

• Journal of Periodontal and Implant Science
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• v.32 no.1
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• pp.89-112
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• 2002

The earliest reports of the use of electrical energy to directly stimulate bone healing seem to be in 1853 from England, the techniques involved the introduction of direct current into the non-united fracture site percutaneously via metallic needles, with subsequent healing of the defect. One endpoint of the periodontal therapy is to generate structure lost by periodontal diseases. Several procedural advances may support regeneration of attachment, however, regeneration of alveolar bone does not occur consistently. Therefore, factors which stimulate bone repair are areas for research in periodontal reconstructive therapy. Effects of cytokines or growth factors on bone repair are examples of such areas. Another one is electrical current which occurs in bone naturally, so that such bone may be particularly susceptible to electrical therapy. The purposes of this study were to observe the effects of electrical stimulation on the normal periodontium, to determine whether the electricity is the useful means for periodontal regeneration or not. Forty rats weighted about 100 gram were used and divided into 4 groups, the first group, there was no electrical stimulation with the connection of electrodes only. In the second group, there was stimulated by the 10 mA during 10 minutes per a day, in the third group was stimulated by the 25 mA , and the fourth by the 50 mA. At 3, 5, 10 and 15 days post-appliance , two rats in each group were serially sacrificed. and the maxillae and the mandible processed to paraffin, and the specimens were prepared with Hematoxylin-Eosin stain for the light microscopic evaluation. The results of this study were as follows : 1. There was the distinct reversal line on the lingual alveolar crest, whereas a little changes in the labial alveolarcrest to the duration and amount of currents. 2. In 50 mA group, the cells were highly concentrated at the apex of anterior teeth, and was observed the necrotic tissue. In posterior root apex, the hypercementosis was appeared, and newly formed cementum layer has been increased continuously with the time. 3. The periodontal ligament fiber and Sharpey's fiber were arranged in order, and the bone trabeculae were increased as the experiment proceeded by, relatively the bone marrows were decreased. 4. In the pulp tissue, the blood vessels were increased with blood congestion in the experimetal specimens remarkably, and the dentinal tubules were obstructed . 5. The osteoblasts in alveolar bone proper had been showed highly activity, and also observed the formation of bone trabeculea. In the conclusion, it was suggested that the electrical stimulation has influence on the periodontium and the pulp tissue. However, there might be the injurious effects.

• International Area Studies Review
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• v.20 no.1
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• pp.53-78
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• 2016

This study is to analyze the effects of both the bilateral FTA and a home and its trade partner's FTAs on the trade with 62 country-pair panel data over the period of 2003-2013 using the gravity model and the spatial autoregressive model. First, the study analyzes how the bilateral FTAs affect the trade using the gravity model and the spatial model. Next, the article analyzes how the home and its trade partners' FTAs affect their trade using only the spatial model under controlling the bilateral FTA. The empirical results are summarized as the followings: first, the spatial mode fits well more than the gravity model in analyzing the relationship between the bilateral FTA and trade. It implies that the spatial spillover effect of FTA is important in the international trade with FTA. Second, the bilateral FTA plays a role in expanding the trade between or among the FTA members as proved by the previous studies. Third, the more the home and its trade partners' FTAs, the more the bilateral trade are extended. Fourth, with the bilateral FTAs, as the home and its trade partners enter into more FTAs, the bilateral trade reduces due to trade diversion effects. In conclusion, this study provides a political implication that in order to increase the trade volume, a country enters into as many FTAs as possible because the effects of the bilateral FTAs would decrease.

• Information Systems Review
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• v.22 no.2
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• pp.167-199
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• 2020

The ICT-based curation as a series of experiences with the mobile exhibition-guide applications or guide programs in art galleries helps visitors fully immersed in the exhibition and allows them to have more informative and convenient guide experience at art galleries. This study aims to verify how the factors of ICT-based curation affects the commitment and satisfaction of visitors at art galleries, figure out whether the visitors' commitment has effects on their satisfaction, and then finally test the impact of their commitment and satisfaction on their revisit intention. In order to validate the cause-and-effect relationships between these factors, the ICT-based curation in this paper is categorized into five factors - gamification, quality of image/video information, quality of sound/text information, contextual offer, and instant connectivity. The main results of the study are as follows. First, only the gamification has significantly positive effects on the commitment of art gallery visitors, while other two factors - the instant connectivity, and the quality of sound/text information - have significantly positive effects on the satisfaction of visitors. Second, the commitment of visitors also has significantly positive effects on their satisfaction. Third, the commitment of the visitors don't have significantly positive relationship with their intention of revisit, but the satisfaction of the visitors have significantly positive relationship with their intention of revisit.