• Asian-Australasian Journal of Animal Sciences
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• v.25 no.11
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• pp.1511-1514
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• 2012

Epistasis that may explain a large portion of the phenotypic variation for complex economic traits of animals has been ignored in many genetic association studies. A Baysian method was introduced to draw inferences about multilocus genotypic effects based on their marginal posterior distributions by a Gibbs sampler. A simulation study was conducted to provide statistical powers under various unbalanced designs by using this method. Data were simulated by combined designs of number of loci, within genotype variance, and sample size in unbalanced designs with or without null combined genotype cells. Mean empirical statistical power was estimated for testing posterior mean estimate of combined genotype effect. A practical example for obtaining empirical statistical power estimates with a given sample size was provided under unbalanced designs. The empirical statistical powers would be useful for determining an optimal design when interactive associations of multiple loci with complex phenotypes were examined.

• Communications for Statistical Applications and Methods
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• v.26 no.6
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• pp.527-538
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• 2019

This paper considers the issue of obtaining the optimal design in Poisson regression model when the sample size is small. Poisson regression model is widely used for the analysis of count data. Asymptotic theory provides the basis for making inference on the parameters in this model. However, for small size experiments, asymptotic approximations, such as unbiasedness, may not be valid. Therefore, first, we employ the second order expansion of the bias of the maximum likelihood estimator (MLE) and derive the mean square error (MSE) of MLE to measure the quality of an estimator. We then define DM-optimality criterion, which is based on a function of the MSE. This criterion is applied to obtain locally optimal designs for small size experiments. The effect of sample size on the obtained designs are shown. We also obtain locally DM-optimal designs for some special cases of the model.

• Journal of Preventive Medicine and Public Health
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• v.40 no.2
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• pp.114-121
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• 2007

Power and sample size estimation is one of the crucially important steps in planning a genetic association study to achieve the ultimate goal, identifying candidate genes for disease susceptibility, by designing the study in such a way as to maximize the success possibility and minimize the cost. Here we review the optimal two-stage genotyping designs for genomewide association studies recently investigated by Wang et al(2006). We review two mathematical frameworks most commonly used to compute power in genetic association studies prior to the main study: Monte-Carlo and non-central chi-square estimates. Statistical powers are computed by these two approaches for case-control genotypic tests under one-stage direct association study design. Then we discuss how the linkage-disequilibrium strength affects power and sample size, and how to use empirically-derived distributions of important parameters for power calculations. We provide useful information on publicly available softwares developed to compute power and sample size for various study designs.

• The Korean Journal of Applied Statistics
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• v.7 no.1
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• pp.47-58
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• 1994

The farm population survey and the livestock survey are sample surveys related to agriculture. Two new sample designs for these surveys are considered. Shi-Gun(county) estimates in the farm population survey and Shi-Do(county) estimates in the livestock survey can be obtained. Also the sample sizes are reduced. To increase the precision of the estiamtes strarified simple random samples are used and particularly purposive samples are introduced in livestock survey. Lastly the method of management and replacement of samples are investigated for successive occasion survey.

• Journal of the Korean Statistical Society
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• v.29 no.1
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• pp.29-44
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• 2000

In this paper, we consider one-level rotation designs with finite rotation groups such that the design satisfies two basic requirements: all rotation groups are included in any given survey period, and overlapping rates depend only on the time lag. First we present the necessary number of rotation groups and a rule for the length of time the sample units are to be in or out of the sample to satisfy the requirements. Second, an algorithm is presented to put rotation groups to proper positions in a panel in order to include all finite rotation groups for any survey period. Third, we define an one-level rotation pattern which is invariant in the survey period and has useful properties in practical sense.

• Proceedings of the Korean Statistical Society Conference
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• 2003.10a
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• pp.123-130
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• 2003

We define a broad class of rotation designs whose monthly sample is balanced in interview time, level of recall, and rotation group, and whose rotation scheme is time-invariant. The necessary and sufficient conditions are obtained for such designs. Using these conditions, we derive a minimum variance unbiased generalized composite estimator (MVUGCE). To examine the existence of time-in-sample bias and recall bias, we also propose unbiased estimators and their variances. Numerical examples investigate the impacts of design gap, non-sampling error sources, and two types of correlations on the variance of MVUGCE.

• Journal of the Korean Statistical Society
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• v.27 no.4
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• pp.459-469
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• 1998

Balanced half sample method is a simple variance estimation method for complex sampling designs. Since it is simple and flexible, it has been widely used in large scale sample surveys. However, the usual BHS method overestimate the true variance in without replacement sampling and two-stage cluster sampling. Focusing on this point , we proposed an unbiased BHS variance estimator in a stratified two-stage cluster sampling and then described an implementation method of the proposed estimator. Finally, partially BHS design is explained as a tool of reducing the number of replications of the proposed estimator.

• The Korean Journal of Applied Statistics
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• v.17 no.1
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• pp.61-73
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• 2004

Rotation sampling designs may be classified into two categories. The first type uses the same sample unit for the entire life of the survey. The second type uses the sample unit only for a fixed number of times. In both type of designs, the entire sample is partitioned into a finite number(=G) of rotation groups. This paper is generalization of the first type designs. Since the generalized design can be identified by only G rotation groups and recall level 1, we denote this rotation system as l/G rotation design. Under l/G rotation design, variance and mean squared error (MSE) of generalized composite estimator are derived, incorporating two type of biases and exponentially decaying correlation pattern. Compromising MSE's of some selected l/G designs, we investigate design efficiency, design gap effect, ans the effects of correlation and bias.

• Journal of Fashion Business
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• v.13 no.6
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• pp.89-98
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• 2009

Computer development and new printing technology allow us to express a new type of digital textile designs those were not possible in the past. In this study, watercolor overlaying effect of various colors was tried using airbrush tool in Photoshop program. Photoshop program is a powerful graphic tool and can be used in textile design area to generate various types of designs. Woven texture was also applied to the design to give yarn dyed effects or rich appearance. Photoshop program was also used to develop woven texture without the help of the professional textile CAD. Photoshop channels enables the designers to apply various textures to the image. Plain weave and houndstooth were applied in this study. Colorways of the developed designs having watercolor effect and woven texture by applying Photoshop color adjustment function. Quick and simultaneous changes of colors were possible using this method. The developed textile designs were printed by transfer DTP. Successful textile design prints were expressed and showed watercolor overlaying effect and woven texture. The printed textiles show a little brighter color, and therefore, sample printing is recommendable in case of color sensitive production.

• Proceedings of the Korean Association for Survey Research Conference
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• 2002.11a
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• pp.255-274
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• 2002

We classify rotation sampling designs into two classes. The first class replaces sample units within the same rotation group while the second class replaces sample units between different rotation groups. The first class is specified by the three-way balanced design which is a multi-level version of previous balanced designs. We introduce an extended generalized composite estimator (EGCE) and derive its variance and mean squared error for each of the two classes of design, cooperating two types of correlations and three types of biases. Unbiased estimators are derived for difference between interview time biases, between recall time biases, and between rotation group biases. Using the variance and mean squared error, since any rotation design belongs to one of the two classes and the EGCE is a most general estimator for rotation design, we evaluate the efficiency of EGCE to simple weighted estimator and the effects of levels, design gaps, and rotation patterns on variance and mean squared error.