Objective: Codeine may result in death or respiratory depression in children, particularly who are rapid metabolizer of CYP2D6, therefore it should be used cautiously among children under 12 years of age. This study was to investigate the prescribing pattern of codeine among children according to the age group, prescribed diagnosis, type of medical service and medical specialties. Method: We used Korea Health Insurance Review and Assessment Service-National Patient Sample (HIRA-NPS) database. Study subjects included inpatients or outpatients, who were prescribed codeine between January, 1, 2011 and December, 31, 2011. Contraindicated use of codeine was defined as the use of codeine at least one times under aged 12. Age groups were subclassified according to the <2 years, 2-4 years, 5-8 years, and 9-11 years. Frequently prescribed diagnosis (ICD-10), type of medical service, and medical specialties were also described among codeine users under aged 12. Results: Codeine users were 6,411 inpatients (9,958 prescriptions), and 3,397 outpatients (6,258 prescriptions), respectively. Codeine prescription under 12 years of age were 2.1% (210 prescriptions) among inpatients, and 12.3% (776 prescriptions) among outpatients (p-value<0.05). Outpatient prescriptions of codeine under 12 aged were issued mostly from primary care clinics and frequent diagnosis were unspecified bronchopneumonia (51.6%), and vasomotor rhinitis (23.7%). Conclusion: This study found prescribing of codeine under 12 aged is common in outpatient and primary clinics. Nationwide and community-based efforts should be needed to reduce inappropriate prescribing among children.
Vitamin mineral supplement usage by self-prescription is popular behavior among adolescents. This study was conducted to investigate the behaviors of vitamin·mineral supplement usage and the relationship between demographic variables and supplement usage by healthy adolescents. Nine hundred seventy two boys and girls, aged 13-18 years, attending general middle or high schools were chosen from various cities and rural communities in Korea. As a result, vitamin·]mineral supplements were taken by 31.3% of subjects. Users tended to take vitamin·mineral supplements more frequently when they were healthy than when they suffered from disease. The taking period of supplements was different according to school type such as middle or high school(p<.05), sex(p<.001) and residence of subjects(p<.01). The main information source of supplements was newspaper/magazine/TV, and it was affected by sex(p<.05) and residence(p<.01). Vitamin·mineral supplements were generally recommended by their mothers instead of health professionals. The commonly cited taking reason of supplements was affected by sex(p<.01)and socioeconomic status of family(p<.05). The frequently responded effect obtained from supplement use was recovery from fatigue and it was different according to sex(p<.01). The major mentioned reason of not taking vitamin·mineral supplements by non-users was 'I eat a balanced diet'. The most frequently consumed supplements were vitamin C, followed by multi-vitamins supplements, and this pattern was different according to school type(p<.001), sex(p<.01) and residence(p<.05). These findings show that the behaviors of vitamin·mineral supplement usage by subjects are not resonable, and their supplement usage tends to be affected by demographic variables. Therefore, nutritional understanding and education that are intended to form the resonable behaviors toward vitamin·mineral supplement usage of adolescents should be provided with considering the relationship between demographic variables and supplement usage.
Background: The treatment goal for patients with chronic hepatitis B infection is to prevent progression of the disease to cirrhosis and hepatocellular carcinoma. Current therapies include standard and pegylated interferon-alfa and nucleoside/nucleotide analogues: lamivudine, adefovir, entecavir, telbivudine, clevudine, and tenofovir. This study aims to analyze changes in the prescribing patterns of chronic hepatitis B (CHB) medications in South Korea between 2013 and 2014. Methods: A cross-sectional study was conducted using National Patients Sample data compiled by the Health Insurance Review and Assessment Service from 2013 and 2014. Patients with CHB were identified with Korean Standard Classification of Diseases code-6 (B18.0 and B18.1) and those who were maintaining active prescriptions with CHB medications covering the index date (December $1^{st}$, each year) were included. The utilization of antiviral therapy was investigated during 2013 and 2014. Results: A total of 4,204 and 4,552 patients in 2013 and 2014 respectively, were included in the analysis. The proportion of male patients was two of third and the patients 41-60 years old accounted for 60% of all analyzed patients. The most utilized drug was entecavir (55.1% in 2013 and 44.8% in 2014) and the second most utilized drug was tenofovir in both years (18.8% in 2013 and 29.0% in 2014). The percentage of combination therapy was 13.6% and 13.1% in 2013 and 2014, respectively. The proportion of tenofovir prescriptions was increased in 2014 compared with 2013. Conclusion: With the development of new drugs and the changes in clinical practice guidelines, the prescription pattern of the antiviral agents for patients with CHB has changed. The rate of utilization of tenofovir has increased.
In the relationship between post-modern feminism and the body. the body of women, which has been taken as 'other' by dominant arguments, has escaped from the fixed idea at post-modern times and the post-modern feminists tried to escape from the taste of the times about body image that was prevalent in the former times.'The taste of the times' here means the fixed physical form of ideal women's body by the educational custom, and it includes the educational prescription which establishes the docile body of women. This kind of educational custom aims at the perfect and permanent restriction on size, shape, desire, attitude and movement as well as on the overall demeanor and each part of the body. And the custom produces 'dependent and trained'. that is, inferiorized women's body. Hence, this paper points out that the feminity as a fixed Physical form should be overcome in order to move forward, and as one part of the effort, it attempts to analyze the designs which deformed and distorted women's body in 1990s. This research indicates that the work, which tries to deviate the fantasized and casted women's mystery, has been closely connected with the expression of 'non-separate bodies' and 'irregular body shapes' in 1990s, which aims at escaping from the fixation of women's body Image. Therefore, it is concluded that the target design trend of this research, which expressed the deformation and perversion of the body, provides the anti-these against the ideal body image of women and the these of feminity. which have been reproduced in various methods and patterns throughout the public and the culture on the whole by expressing the refusal and deviation of the existing women's body image through the post-fixation of the body pattern.
Objectives : The Hwabyung Research Center of The Korean Society Of Oriental Neuropsychiatry has attempted to develop the 'Clinical Guidelines for Hwabyung'. Methods : The Hwabyung Research Center constructed a committee of experts and advisory group. Relevant literature was collected and evaluated in order to find out effective Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, and cupping of Hwabyung. Results : We found some evidences that proved the effectiveness of Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, and cupping in the treatment of Hwabyung. 1) We recommend Pharmacotherapy (Herbal medicine), acupuncture and moxibustion, cupping, psychotherapy and management, other therapeutic approaches and education for Hwabyung. 2) Pharmacotherapy (Herbal medicine) should be determined according to the pattern identification of Korean medicine. Further, the prescription should be cost-effective, safe and have no side effects. Also, the interaction between Herbal and Western drugs should be considered carefully. 3) There are general acupuncture, scalp acupuncture, Pharmacopuncture, Sa-am acupuncture as well as acupuncture treatments for Hwabyung. 4) Moxibustion and cupping are useful, relieving various somatic symptoms of Hwabyung. Conclusions : Pharmacotherapy (Herbal medicine), Acupuncture and Moxibustion, Cupping for Hwabyung were studied. We hope that the 'Clinical Guidelines for the Treatment of Hwabyung' are helpful for oriental medical doctors and patients.
This research was planned and executed to evaluate how the composition of Yack-sun tea can affect the health conditions of people who are suffering from diet-related such as being overweight, are obese and have hyperlipidemia, by taking Yack-sun tea in a form of a nutritional supplement with our daily meals. We produced Kangjieum with Lycium chinense Mill., Polygonum multflorum Thunb, Cassia tora L., Crataegus pinnatifida Bge and Salvia miltiorrhiza Bge. Thus, we approach of oriental diet therapy area research of Kangjieum and analysis proximate composition, water soluble antioxidant content. The content(%, dry basis) of total carbohydrate was 60.23%, crude protein was 18.18%, crude ash was 11.36% and crude fat was 10.23% in Kangjieum. Total water soluble antioxidant content was 1.027 ${\mu}g/m{\ell}$ of Kangjieum. We think that scientific and objective evaluation was done on the components of the Kangjieum prescription. This basic data could help guide the application of oriental medicinal resources into other foods and serve as a stepping-stone for use of Kangjieum in the burgeoning field of nutraceutical foods. Last, the scientific effects of oriental medicinal foods developed according to oriental medicinal theory. This theory is believed to be essential for government policy development concerning validation of medicinal effects and assessment, with the aim of fostering systematic development and providing guidance to food development in the interest of national health.
Park, Dong-Kyun;Kim, Jong-Hun;Kim, Jae-Kwon;Jung, Eun-Young;Lee, Young-Ho
The Journal of the Korea Contents Association
/
v.11
no.8
/
pp.23-32
/
2011
U-health services have been progressed as treatment and management for specific diseases and prevention services for providing the behavior management to customers according to the increase in chronic patients. The conventional U-health services provide required services and bio-information monitoring only through remote diagnoses and counsels and that represent limitations in preventing and managing metabolic syndrome patients like chronic patients. Thus, in this study a multi platform based U-health service model for managing the health of chronic patients is proposed. The multi-platform based U-health service model can provide continuous health information, diet, and exercise services regardless of the location of customers through PCs and smart phones. In addition, it is able to provide prescription services to doctors and nurses using a CDS (Clinical Decision Support) module based on clinical information. Doctors can identify the life pattern of patients through a behavior modification program and provide customized services to patients. The U-health service model provides effective services in multi-platform environments to customers and that will improve the health of chronic patients.
Objectives: The experiment was to estimate the value of Saengmaegsan as a therapeutic anti-aging agent with an analysis of ingredients and their bio-activating effects by enzymologic methods. Methods: We analyzed anti-aging effects of the ingredients of Saengmaegsan being Liriope Platyphylla, Schizandrae Chinensis, and Schizandrae Chinensis. Results: In Liriope Platyphylla and Schizandrae Chinensis, reducing sugar concentration was shown at the highest level. Of mineral contents, K+ and Na+ were the highest in Saengmaegsan and each ingredient also, and then Ca++ and Al. The amount of polyphenol showed was in order Schizandrae Chinensis > Saengmaegsan > Panax Ginseng > Liriope Platyphylla. The electron donating ability of Schizandrae Chinensis doubled that of Saengmaegsan and Panax Ginseng, at the same time that one per 1 ml in Saengmaegsan was significantly found the greatest level as compared to each single ingredient. SOD-like activity was high in Saengmaegsan and Schizandrae Chinensis. SOD-like activity of Saengmaegsan was higher than in single components. Nitric oxide inhibition in pH 1.2 was high in Saengmaegsan and Schizandrae Chinensis, and for per 1 ml it showed the same pattern as above. In pH 3.0 the result was not different from in pH 1.2. Xanthine oxidase inhibition was high in Schizandrae Chinensis and for per 1 ml showed the greatest activity in Liriope Platyphylla. Tyrosinase inhibition in Omija was the most noticeable, and for per 1 ml was Liriope Platyphylla more than any others. Conclusions: With this analysis of ingredients, it is proven that Saengmaegsan and each component fosters antioxidation. On the whole, the composite prescription Saengmaegsan was superior to each individual component.
Park, Ji-Yeun;Lee, Soon-Ho;Kim, Song-Yi;Park, Hi-Joon
Korean Journal of Acupuncture
/
v.34
no.2
/
pp.88-99
/
2017
Objectives : Saam acupuncture initiated by Saamdoin in $17^{th}$ century is one of the most widely adopted acupuncture techniques used by Korean medical doctors in clinic. Our study aimed to analyze the application of the Saam acupuncture method to pain diseases based on the literature data. Methods : Based on the contents described in "(Do Hae Kyo Kam) Saam's acupuncture method", the texts related to pain condition were analyzed. The frequency of prescription of Saam acupuncture method was analyzed, and then the relationships between each acupoint were visualized by network analysis and hierarchical cluster analysis for the quantitative aspect. Results and conclusions: In our study, Lung tonifying and Liver tonifying acupuncture were the most frequently used method for the treatment of pain disease. As the acupoints, BL66 and SI5 were used the most frequently. It was found that visceral pattern identification was considered as the most important factor in the selection of the Saam acupuncture method. Network analysis and hierarchical clustering analysis showed that each acupoint was closely related to other acupoints, and most of them were connected more closely according to the method of Saam acupuncture operation. The experiential prescriptions of Saam acupuncture were classified as an independent group. In the future, fundamental research on the principle of Saam acupuncture method is needed for the various diseases, and research for the clinical efficacy and the mechanism of Saam acupuncture method should be preceded.
Journal of the Korean Institute of Intelligent Systems
/
v.24
no.5
/
pp.542-547
/
2014
This paper describes the medical and IT convergence system using a smart phone and a heuristic method for the measurement of the dripping speed of the liquid in a drip chamber, which can estimate the remaining time using pattern recognition and difference image from video frame information based on Android technology. The video frames were first made using a smartphone camera and we calculated the difference image between the n image and the (n-1) image and then changed into binary images using the threshold value. At this point, it is very important to find an optimal threshold value using heuristic method to recognize the dripping of the liquids. In addition, the user can adjust the dripping speed according to the doctor's prescription, exactly like watching the progress bar of a mobile application. The experiment results show that our method using video processing technique accurately measures the dripping speed for a wide range of speeds that are sufficient for ordinary practice.
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