• Journal of the Health Care and Life Science
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• v.9 no.1
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• pp.11-25
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• 2021

This study is to analyze the relationship between self-esteem and happiness of parents and children in the 4th-grade elementary school and the 1st-grade of middle school using Korean Children and Youth Panel Survey(KCYPS) 2018 data by the National Youth Policy Institute. The context of analysis is to determine how parents' self-esteem and happiness affect parenting attitudes, and furthermore, how they affect their children's academic activities, self-esteem and happiness. This study is able to explore the level at which self-esteem and happiness, the mental health measure of children and adolescents, were linked to parental self-esteem and happiness. And it suggests that the importance of the role of a parent as a family background has been confirmed in promoting the healthy development of children and adolescents.

• Horticulture, Environment, and Biotechnology : HEB
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• v.59 no.6
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• pp.875-888
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• 2018

Tulip (Tulipa L.) is one of the most important ornamental geophytes in the world. Analysis of molecular variability of tulips is of great importance in conservation and parental lines selection in breeding programs. Of the 70 genic microsatellites, 15 highly polymorphic and reproducible markers were used to assess the genetic diversity, structure, and relationships among 280 individuals of 36 wild and cultivated tulip accessions from two countries: Iran and the Netherlands. The mean values of gene diversity and polymorphism information content were 0.69 and 0.66, respectively, which indicated the high discriminatory power of markers. The calculated genetic diversity parameters were found to be the highest in wild T. systola Stapf (Derak region). Bayesian model-based STRU CTU RE analysis detected five gene pools for 36 germplasms which corresponded with morphological observations and traditional classifications. Based on analysis of molecular variance, to conserve wild genetic resources in some geographical locations, sampling should be performed from distant locations to achieve high diversity. The unweighted pair group method with arithmetic mean dendrogram and principal component analysis plot indicated that among wild tulips, T. systola and T. micheliana Hoog exhibited the closest relationships with cultivated tulips. Thus, it can be assumed that wild tulips from Iran and perhaps other Middle East countries played a role in the origin of T. gesneriana, which is likely a tulip species hybrid of unclear origin. In conclusion, due to the high genetic variability of wild tulips, they can be used in tulip breeding programs as a source of useful alleles related to resistance against stresses.

• International journal of advanced smart convergence
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• v.8 no.3
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• pp.151-160
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• 2019

Korea has the highest suicide rate among the OECD countries, and the suicide rate is highest among young adults in their 20s, most of whom are university students. Therefore, suicide among Korean university students is a public health issue that is of interest to us. The purpose of this study is to investigate the factors affecting the suicidal ideation of university students in Korea, and to use them as a basis to establish effective intervention for university suicide prevention through it. This was a cross-sectional descriptive study using convenience sampling method. The participants were 344 university students at universities in S and G cities. Data were collected with a structured questionnaire and analyzed using descriptive analysis, t-test, ANOVA, Pearson correlation coefficients, and hierarchical regression analysis using with the SPSS/Win 23.0 program. There was a significant correlation between depression (r=.45, p<.001), drinking alcohol (r=.14, p=.008), social support (r=-.26, p<.001), quality of life (r=-.46, p<.001), and suicidal ideation. In the first step of hierarchical regression analysis, satisfaction of school life (${\beta}=.198$, p<.001) was the significant factor influencing the suicidal ideation. Explanatory power was 25.2%. In the second step of the hierarchical regression analysis, absence of parents (${\beta}=-.095$, p=.044), depression (${\beta}=.247$, p<.001), quality of life (${\beta}=-.280$, p<.001), and explanatory power were increased to 42.0%. The results of the study indicate the need to actively identify the group of university students in their 20s with high risk of suicide through continuous evaluation of depression, and to improve the quality of life as a method of preventing suicide. In addition, the effect of absence of parents on the suicidal ideation among Korean university students suggests that parental support may play an important role in suicide prevention.

• Journal of Microbiology and Biotechnology
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• v.31 no.11
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• pp.1591-1600
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• 2021

Streptomyces coelicolor is a filamentous soil bacterium producing several kinds of antibiotics. S. coelicolor abs8752 is an abs (antibiotic synthesis deficient)-type mutation at the absR locus; it is characterized by an incapacity to produce any of the four antibiotics synthesized by its parental strain J1501. A chromosomal DNA fragment from S. coelicolor J1501, capable of complementing the abs- phenotype of the abs8752 mutant, was cloned and analyzed. DNA sequencing revealed that two complete ORFs (SCO6992 and SCO6993) were present in opposite directions in the clone. Introduction of SCO6992 in the mutant strain resulted in a remarkable increase in the production of two pigmented antibiotics, actinorhodin and undecylprodigiosin, in S. coelicolor J1501 and abs8752. However, introduction of SCO6993 did not show any significant difference compared to the control, suggesting that SCO6992 is primarily involved in stimulating the biosynthesis of antibiotics in S. coelicolor. In silico analysis of SCO6992 (359 aa, 39.5 kDa) revealed that sequences homologous to SCO6992 were all annotated as hypothetical proteins. Although a metalloprotease domain with a conserved metal-binding motif was found in SCO6992, the recombinant rSCO6992 did not show any protease activity. Instead, it showed very strong β-glucuronidase activity in an API ZYM assay and toward two artificial substrates, p-nitrophenyl-β-D-glucuronide and AS-BI-β-D-glucuronide. The binding between rSCO6992 and Zn²⁺ was confirmed by circular dichroism spectroscopy. We report for the first time that SCO6992 is a novel protein with β-glucuronidase activity, that has a distinct primary structure and physiological role from those of previously reported β-glucuronidases.

• Journal of Industrial Convergence
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• v.20 no.4
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• pp.85-93
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• 2022

The purpose of this study was to verify whether strengthening family competency plays a mediating role in the influence of parents' parenting efficacy on the independent life of children with developmental disabilities. The subjects of the study were 146 parents with developmental disabilities, and data analysis using the SPSS 22.0 program was conducted. The mediating effect was Baron and Kenny Hierarchical regression analysis and sobel-test were conducted. As a result of the study, the positive effect of parents' parenting efficacy on the level of self-reliance and strengthening family competency of children with developmental disabilities was verified. In addition, the positive mediating effect of strengthening family competency was verified between the parenting efficacy of parents and the level of independence of children with developmental disabilities. As a result of the study, it is important to support parents' parenting and family capacity enhancement to support the independence of children with developmental disabilities.

• Journal of Industrial Convergence
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• v.20 no.10
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• pp.147-156
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• 2022

The purpose of this paper was to verify the mediated effect of grit in the relationship with the effect of youth social support on aggression. To this end, data from the 2018 Children and Youth Panel (KCYPS) survey were used, and 2,590 first-year middle school students were selected and analyzed. As for the analysis method, Baron & Kenny's regression analysis and Sobel Test were performed. As a result of the main analysis, first, it was found that grit had a partial mediating effect in the effect of parental support, a sub-factor of social support of adolescents, on aggression. Second, it was found that grit had a partial mediating effect in the effect of friend support, a sub-factor of social support of adolescents, on aggression. Third, it was found that grit had a partial mediating effect in the effect of teacher support, a sub-factor of social support of adolescents, on aggression. Based on the above research results, various program development and policy alternatives that can reduce youth aggression and improve grit were suggested.

• Clinical and Experimental Pediatrics
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• v.65 no.1
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• pp.35-46
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• 2022

Background: The growing prevalence of overweight and/or obese children is an important public health problem in both developed and developing countries. Although the association of obesity between parents and their children is well known, its underlying mechanisms are not well established. Purpose: This meta-analysis examined parent-child (PC) relationships in obesity and identified factors such as world region and country income level that may influence this relationship. Methods: We identified all related studies published between January 1, 2015 and May 31, 2020 by conducting a literature search using the MeSH terms "obesity," "overweight," "body mass index," "parent," "child," "associate," and "relate" in the PubMed database in English. Results: The meta-analysis of 23 studies that reported an odds ratio (OR) for parent and child obesity associations found a significant association between parents and children who were overweight or obese (pooled OR, 1.97; 95% confidence interval, 1.85-2.10). A meta-regression analysis was used to examine the sources of interstudy heterogeneity. The association between parent and child obesity was higher in Asia than in Europe and the Middle East and higher in high-income countries than in middle-or low-income countries. In addition, a higher association between parent and child obesity was found when both parents were obese than when only the father or mother was obese. This study from multiple countries indicates a significant PC relationship in weight status that varies according to PC pair type, parent and child weight statuses, world region, and country income level. Conclusion: These results demonstrate that the risk of childhood obesity is greatly influenced by parental weight status and indicate that parents could play an important role in preventing child obesity.

• Biomolecules & Therapeutics
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• v.31 no.3
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• pp.253-263
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• 2023

The biogenesis and biological roles of extracellular vesicles (EVs) in the progression of liver diseases have attracted considerable attention in recent years. EVs are membrane-bound nanosized vesicles found in different types of body fluids and contain various bioactive materials, including proteins, lipids, nucleic acids, and mitochondrial DNA. Based on their origin and biogenesis, EVs can be classified as apoptotic bodies, microvesicles, and exosomes. Among these, exosomes are the smallest EVs (30-150 nm in diameter), which play a significant role in cell-to-cell communication and epigenetic regulation. Moreover, exosomal content analysis can reveal the functional state of the parental cell. Therefore, exosomes can be applied to various purposes, including disease diagnosis and treatment, drug delivery, cell-free vaccines, and regenerative medicine. However, exosome-related research faces two major limitations: isolation of exosomes with high yield and purity and distinction of exosomes from other EVs (especially microvesicles). No standardized exosome isolation method has been established to date; however, various exosome isolation strategies have been proposed to investigate their biological roles. Exosome-mediated intercellular communications are known to be involved in alcoholic liver disease and nonalcoholic fatty liver disease development. Damaged hepatocytes or nonparenchymal cells release large numbers of exosomes that promote the progression of inflammation and fibrogenesis through interactions with neighboring cells. Exosomes are expected to provide insight on the progression of liver disease. Here, we review the biogenesis of exosomes, exosome isolation techniques, and biological roles of exosomes in alcoholic liver disease and nonalcoholic fatty liver disease.

• Journal of the Korean Applied Science and Technology
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• v.39 no.2
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• pp.169-181
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• 2022

The study is a descriptive research to determine relationships between variables: perceived parenting attitude of nursing students, emotional intelligence, problem-solving ability and look at the effect of perceived parenting attitude on emotional intelligence and problem-solving ability of nursing students. We collected 134 data nursing students who are attending J university in C do and analyzed 126 data of them using the SPSS/WIN 22.0 version. The study period lasted two weeks, going from Nov 29 to Dec 13, 2021. The factor influencing emotional intelligence and problem-solving ability of perceived parenting attitude is emotional warmth attitude(B=.349, p=.001),(B=.255, p=.018) with 25.1%, 22.3% of the total explanatory power. It will need to be informed that emotional warmth attitude of perceived parenting attitude when educating for parents is a important factor to improve emotional intelligence and problem-solving ability of children who are future nurses and be used it as a basic data of parenting education for a desirable parental role.

• Industry Promotion Research
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• v.5 no.3
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• pp.53-60
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• 2020

This paper describes the role of counselors' transitional object for the therapeutic activation of clients who have lost the function of selfobject based on Heinz Kohut's Self theory. In this study, it was an opportunity to confirm that human beings need self-target throughout their lives. Next, referring to the process of metamorphic internalization, infants return to reality from a fantasy world, experiencing parental limitations due to optimal frustration through self-targeting. The role of a counselor as a transfer target shall ensure that the counsellor establishes an cohesive self-identity and uses the appropriate self-target. And they should empathize with the over-the-topism and flauntism of the physician, and the counselor should be the object of idealization, giving the interviewer the opportunity to be recognized and identified. The counselor may provide the best frustration for the counsellor during the consultation process. When the counselor acknowledges his mistake, the counselor looks at the counselor realistically and builds a healthy self to achieve transformative internalization. If you form an cohesive self to a physician through counseling, you can empathize with others and form a healthy human relationship. Then you can control your emotions and have a vision. And the patient realizes that he or she has no choice but to live by having a relationship with the right person throughout his or her life.