• 대한기계학회논문집
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• 제19권3호
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• pp.639-646
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• 1995

The objective of this study is to minimize the weight of a damped anisotropic roto-bearing system considering whirl natural frequency and stability. The system is modeled as an assemblage of rigid disks, flexible shafts and discrete bearings. The system design variables are the crosssectional areas of shaft elements and the properties of bearings. To analyze the system, the polynomial method which is derived by rearranging the calculations performed by a transfer matrix method is adopted. For the optimization, the optimization software IDOL (Integrated Design Optimization Library) which is based on the Augmented Lagrange Multiplier (ALM) method is employed. Also, an analytical design sensitivity analysis of the system is used for high accuracy and efficiency. To demonstrate the usefulness of the proposed optimal design program incorporating analysis, design sensitivity analysis, and optimization modules, a damped anisotropic rotor-bearing system is optimized to obtain 34$ weight reduction.

• 정보처리학회논문지A
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• 제13A권7호
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• pp.589-598
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• 2006

본 논문에서는 블루투스 무선 링크를 이용한 실시간 오디오 스트리밍을 위해 DSP를 내장한 SoC (System-on-Chip) 플랫폼 상에서 임베디드 블루투스 솔루션의 개발과 최적화에 대해 설명한다. 개발된 솔루션을 이식성을 고려해서 가상 운영체제 상에서 구현된 임베디드 블루투스 프로토콜 스택, 프로파일과 타겟 멀티미디어 SoC의 특성을 이용한 최적화 기법들을 포함한다. 수요 최적화 기법으로는 SoC 내의 스크래치 패드 메모리의 활용을 통한 메모리 접근 최소화, DSP 연산과 병렬 메모리 접근 명령을 이용한 코덱 구현, 무선 통신 환경을 고려한 동적 오디오 품질 조정 등이 있다. 실험 결과는 본 연구에서 제안한 최적화 기법을 적용한 임베디드 솔루션은 별도의 외부 메모리 없이 고품질 오디오 스트리밍을 지원할 수 있음을 보여준다.

• 한국전산구조공학회논문집
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• 제33권4호
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• pp.217-224
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• 2020

본 논문에서는 초고층 건물의 철근콘크리트 아웃리거 벽체 개구부의 최적설계를 위한 수학적 최적화 프레임워크를 제시하였다. 전용 유한요소해석 프로그램을 이용하여 아웃리거 벽체를 해석하였으며 깊은 보의 스트럿-타이 거동을 고려하여 개구부를 배치하였다. 최적화를 위해 파이썬 SciPy 라이브러리 중 순차이차계획법(Sequential Quadratic Programming)을 이용하여 제약 경계 최적화를 수행하였다. 최적화에 필요한 미분가능한 연속 함수를 얻어내기 위해 선형 보간법을 사용하였으며, 최적화 프로그램의 효율성을 위해 데이터베이스를 이용하였다. 2변수 최적화의 결과를 탐색 알고리즘의 이동 경로를 통해 살펴본 결과 알고리즘이 최적화된 결과를 효율적으로 찾아냄을 확인하였다. 그리고 개구부의 폭을 모두 같게 설정한 것이 아닌 각각의 개구부의 크기를 개별 변수로 설정하였을 경우 목적함수의 값이 최소화되어 더 우수한 최적화 결과를 도출함을 확인하였다. 또한, 최적화의 과정에 있어 데이터베이스를 이용할 경우 최적화 시간을 효과적으로 단축시킬 수 있음을 확인하였다.

• 한국소음진동공학회논문집
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• 제19권12호
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• pp.1356-1363
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• 2009

The aim of this research is to construct eigenfrequency optimization codes for plates with Arbitrary Rank Microstructures. From among noise factors, resonance sound is main reason for floor's solid noise. But, Resonance-elusion design codes are not fixed so far. Besides, The prediction of composite material's capability and an resonance elusion by controlling natural frequency of plate depend on designer's experiences. In this paper, First, using computer program with arbitrary rank microstructure, variation on composite material properties is studied, and then natural frequency control is performed by plate topology optimization method. The results of this study are as followed. 1) Programs that calculate material properties along it's microstructure composition and control natural frequency on composite material plate are coded by Homogenization and Topology Optimization method. and it is examined by example problem. 2) Equivalent material properties, calculated by program, are examined for natural frequency. In this paper, Suggested programs are coded using $Matlab^{TM}$, Feapmax and Feap Library with Homogenization and Topology Optimization method. and Adequacy of them is reviewed by performing the maximization or minimization of natural frequency for plates with isotropic or anisotropic materials. Since the programs has been designed for widely use. If the mechanism between composite material and other structural member is identified, extension application may be possible in field of structure maintenance, reinforcement etc. through application of composite material.

• 대한의생명과학회지
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• 제15권2호
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• pp.105-112
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• 2009

The screening of the anti-cancer activity of the chemical library provided 2-thio-4-aminopyrimidine as the initial hit. The confirmation of structure and biological effect of hit was performed by synthesis and biological evaluation. The optimization of hit was performed by derivatization of substituents while keeping the core structure. The evaluation of growth inhibitory activity was carried out using SRB assay against 6 human cancer cell lines and human fibroblast. The growth inhibitory activity of compounds showed substituent dependency and more than 5 compounds showed complete growth inhibition of cancer cell lines at 10 ${\mu}M$ concentration. Chemical library screening followed by synthetic modification provided possibility that 2-thio-4-aminopyrimidine can be used as a new scaffold for the development of anti-cancer agent.

• Journal of Microbiology and Biotechnology
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• 제24권3호
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• pp.408-420
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• 2014

Yeast surface-displayed antibody libraries provide an efficient and quantitative screening resource for given antigens, but suffer from typically modest library sizes owing to low yeast transformation efficiency. Yeast mating is an attractive method for overcoming the limit of yeast transformation to construct a large, combinatorial antibody library, but the optimal conditions have not been reported. Here, we report a large synthetic human Fab (antigen binding fragment) yeast surface-displayed library generated by stepwise optimization of yeast mating conditions. We first constructed HC (heavy chain) and LC (light chain) libraries, where all of the six CDRs (complementarity-determining regions) of the variable domains were diversified mimicking the human germline antibody repertoires by degenerate codons, onto single frameworks of VH3-23 and $V{\kappa}1$-16 germline sequences, in two haploid cells of opposite mating types. Yeast mating conditions were optimized in the order of cell density, media pH, and cell growth phase, yielding a mating efficiency of ~58% between the two haploid cells carrying HC and LC libraries. We constructed two combinatorial Fab libraries with CDR-H3 of 9 or 11 residues in length with colony diversities of more than $10^9$ by one round of yeast mating between the two haploid HC and LC libraries, with modest diversity sizes of ${\sim}10^7$. The synthetic human Fab yeast-displayed libraries exhibited relative amino acid compositions in each position of the six CDRs that were very similar to those of the designed repertoires, suggesting that they are a promising source for human Fab antibody screening.

• 한국컴퓨터정보학회논문지
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• 제24권2호
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• pp.119-126
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• 2019

As interest in augmented reality has increased recently, attempts have been made to incorporate augmented reality into various fields. In implementing augmented reality, the method by which markers are used is to extract feature points of markers to recognize 3D coordinates and, in some cases, it is necessary to recognize multiple markers simultaneously. Therefore, this paper proposes optimization methods for recognising multiple markers at the same time. Unity 3D and augmented reality library Vuforia are used to implement the experimental environment. The augmented reality program produced was implemented in an application form and tested using a mobile camera. We looked for optimization methods for manufacturing markers directly and for recognizing multiple markers through changes in the experimental environment. The results of the experiment can provide a higher recognition rate in an environment where multiple marker recognition is required later.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• 제5권2호
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• pp.63-69
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• 2001

In this study, we shall be concerned with computing in parallel a few of the smallest eigenvalues and their corresponding eigenvectors of the eigenvalue problem, $Ax={\lambda}Bx$, where A is symmetric, and B is symmetric positive definite. Both A and B are large and sparse. Recently iterative algorithms based on the optimization of the Rayleigh quotient have been developed, and CG scheme for the optimization of the Rayleigh quotient has been proven a very attractive and promising technique for large sparse eigenproblems for small extreme eigenvalues. As in the case of a system of linear equations, successful application of the CG scheme to eigenproblems depends also upon the preconditioning techniques. A proper choice of the preconditioner significantly improves the convergence of the CG scheme. The idea underlying the present work is a parallel computation of the Multi-Color Block SSOR preconditioning for the CG optimization of the Rayleigh quotient together with deflation techniques. Multi-Coloring is a simple technique to obatin the parallelism of order n, where n is the dimension of the matrix. Block SSOR is a symmetric preconditioner which is expected to minimize the interprocessor communication due to the blocking. We implemented the results on the CRAY-T3E with 128 nodes. The MPI(Message Passing Interface) library was adopted for the interprocessor communications. The test problems were drawn from the discretizations of partial differential equations by finite difference methods.

• 전자공학회논문지A
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• 제28A권1호
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• pp.74-84
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• 1991

This paper presents an algorithm for technology-dependent logic optimization and technology mapping, and describes a performance-driven logic synthesis system, SILOS, implemented based on the proposed algorithm. The system analyzes circuits and resynthesizes the critical sections such that generated circuit operates opertes within time constraints, using only gate types supported by library for direct implementation. Experimental results show that the system can be a viable tool in synthesizing high-performance logic circuits.

• 한국데이타베이스학회:학술대회논문집
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• 한국데이타베이스학회 1995년도 제4회 멀티미디어 산업기술 학술대회 논문집
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• pp.3-19
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• 1995

시스템 Technology ★ Server Technology - 운영환경구축 ★ Network 구성설계 - ATM, FDDI, NMS ★ Client/Server시스템 구성별 Bench Marking ★ Windows 메뉴 및 GUI 설계 ★다기능 PC 운영환경 설정 시스템 Technology ★ Data Base Technology - DB Administration - BB Performance Tuning ★ System Integration Technology - Application Integration - System Flow Control - Task Control - Applicational Interface - S/W Down Load 시스템 Technology ★ Memory Optimization ★ IBM/Facom Host API ★ 영상전화 Customizing - Intel Proshare ★ Auto Dialing - CTI Link ★ IC-Card Interface 시스템 Technology ★ Sound 처리 - Voice Mail - 음절 처리 ★ Image 처리 ★도움말 처리 - Hyper Text 시스템 Technology ★ Socket Programming - 긴급메일 - Peer to peer message switching ★ Set Up Programming -Install Shield ★ DB Access Programming - DB-Library ★ TCP/IP Programming(중략)