• Journal of Information Processing Systems
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• v.8 no.1
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• pp.67-84
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• 2012

An important amount of clinical data concerning the medical history of a patient is in the form of clinical reports that are written by doctors. They describe patients, their pathologies, their personal and medical histories, findings made during interviews or during procedures, and so forth. They represent a source of precious information that can be used in several applications such as research information to diagnose new patients, epidemiological studies, decision support, statistical analysis, and data mining. But this information is difficult to access, as it is often in unstructured text form. To make access to patient data easy, our research aims to develop a system for extracting information from unstructured text. In a previous work, a rule-based approach is applied to a clinical reports corpus of infectious diseases to extract structured data in the form of named entities and properties. In this paper, we propose the use of a Boolean inference engine, which is based on a cellular automaton, to do extraction. Our motivation to adopt this Boolean modeling approach is twofold: first optimize storage, and second reduce the response time of the entities extraction.

• Child Health Nursing Research
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• v.27 no.4
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• pp.395-403
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• 2021

Purpose: This study aimed to identify the mediating and moderating effects of mindset and psychological collectivism, respectively, on the relationship between grit and nursing intention for children with emerging infectious diseases, including coronavirus disease 2019 (COVID-19), among pediatric nurses. Methods: We conducted a cross-sectional descriptive study with 230 pediatric nurses. Results: Grit directly impacted mindset (β=.27, p<.001) and nursing intention (β=.20, p=.001). The direct effect of mindset on nursing intension (β=.28, p<.001) and the indirect effect of grit on nursing intension via mindset (β=.08, p<.001) were significant. Accordingly, mindset mediated the effect of grit on nursing intention. The effects of grit and psychological collectivism (β=.19, p=.003), respectively, on nursing intention were significant. However, the interaction between grit and psychological collectivism was not significant. Thus, psychological collectivism did not moderate the effect of grit on nursing intention. Conclusion: The findings demonstrate the importance of pediatric nurses' grit and mindset on their intended care for patients in critical situations. Cultivating a gritty culture and developing interventions to enhance nurses' personality traits associated with their performance will be crucial, and such measures are especially salient for pediatric nurses to face the new adjustments required in the era of COVID-19.

• BLOOD RESEARCH
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• v.53 no.4
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• pp.299-306
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• 2018

Background IgG-mediated anaphylaxis occurs after infusion of certain monoclonal antibody-based therapeutics. New in vitro tests are urgently needed to diagnose such reactions. We investigated whether allergens trigger neutrophil oxidative burst (OB) and if neutrophil OB occurs due to allergen-specific IgG (sIgG). Methods Neutrophil OB was measured by dihydrorhodamine 123 flow cytometry using a leukocyte suspension spiked with a very small patch of the allergen crude extract, Dermatophagoides farinae (Der f). The mean fluorescence intensity ratio of stimulated to unstimulated samples was calculated as the neutrophil oxidative index (NOI). Results The Der f-specific NOI (Der f-sNOI) showed a time-dependent increase after Der f extract addition. At 15 min activation, higher Der f-sIgG levels were associated with lower Der f-sNOI values in 31 subjects (P<0.05). This inverse relationship occurs due to the initial blocking effect of free Der f-sIgG. Additionally, neutrophil OB was nearly absent (Der f-sNOI of -1) in two cases: a subject with undetectable Der f-sIgG levels and washed leukocyte suspensions deprived of Der f-sIgG. Conclusion Allergens can trigger neutrophil OB via preexisting allergen-sIgG. Neutrophil OB can be easily measured in a leukocyte suspension spiked with the allergen. This assay can be used to diagnose IgG-mediated anaphylaxis.

• Journal of Korean Critical Care Nursing
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• v.15 no.2
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• pp.14-26
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• 2022

Purpose : This study aimed to understand and describe the nurses' experiences caring for severe COVID-19 patients at isolation room with negative pressure in South Korea. Methods : Data were collected through individual in-depth interviews from February 16 to March 31, 2021 with 11 nurses who had been caring for severe COVID-19 patients at isolation room. Verbatim transcripts were analyzed according to Colaizzi's phenomenological analysis. Results : As a result, 5 theme clusters were extracted about nurses' experiences. The 5 theme clusters, "Adapting to unexpected adversity", "Accepting unresonable and heavy work", "Dulness and disconnection from the outside world", "Changing in perception of new infectious diseases", and "Pathetic isolated patients" emerged. Conclusion : The results of this study provided a deeper understanding of nurses struggling to care for COVID-19 severe patients. This study is expected to be useful in providing basic evidence for improving intensive care practices and for preparing policies in other infection disease situations.

• Journal of the Korean Society of School Health
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• v.34 no.3
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• pp.190-199
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• 2021

Purpose: The study aims to identify factors that influence university students' compliance with infection prevention behaviors in the early stage of COVID-19. Methods: A survey was conducted online from July 29 to August 2, 2020, involving 261 students enrolled in general universities. Frequency analysis, descriptive statistics, t-test, ANOVA, correlation, and multiple regression analysis were carried out on the collected data using SPSS 24.0. Results: The average score of university students' risk perception of COVID-19 was 3.80, while the average score of health risk communication was 3.92. The average score of efficacy beliefs was 4.42 and the average score of practicing infection prevention behaviors was 4.54. Factors influencing the level of infection prevention behaviors were efficacy of preventive behaviors (β=.48 p<.001), health risk communication (β=.16, p=.003), subjective health status (β=.12, p=.015), and the type of college (β=.11, p=.041). Conclusion: In order to improve college students' infection prevention behaviors related to COVID-19, consideration should be given to providing interventions that focus on accurate knowledge and dissemination of accurate information about new infectious diseases and effectiveness of infection preventive behaviors.

• Journal of Korean Public Health Nursing
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• v.36 no.3
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• pp.347-360
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• 2022

Purpose: The purpose of this study was to identify the risk perception, safety climate and preventive behaviors of COVID-19 infections, and to verify the factors influencing the adoption of preventive behaviors by health care workers. Methods: A mixed-method approach was used based on a survey carried out in a general hospital. Quantitative data (N=181) were collected through a questionnaire and analyzed using multiple regression. Qualitative data (N=8) were collected through individual interviews and analyzed through Colaizzi's phenomological research method. Results: The factors influencing adoption of preventive behaviors by health care workers were safety climate (β=.41, p<.001), education (β=-.20, p=.025), work unit (β=-.16, p=.032), and risk perception (β=.15, p=.020). The explanatory power was 28.3%, and they have shown that these health care workers felt 'the threat of a pandemic like a battlefield', experienced 'struggle with quarantine rules' and realized 'the reality of infection control and the reorganization for change'. Conclusion: The findings of this study indicate that to increase the adoption of infection control preventive behaviors by health care workers when faced with new infectious diseases in the future, it is necessary to establish organizational support and a safe climate. This study confirms the need for preemptive support and education.

• Journal of the Korean Society for Industrial and Applied Mathematics
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• v.26 no.4
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• pp.280-295
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• 2022

This paper contains an introduction to industrial problems, solutions, and results conducted with the Korea Association of Machinery Industry. The client company commissioned the problem of upgrading the method of identifying global supply risky items. Accordingly, the factors affecting the supply and demand of imported items in the global supply chain were identified and the method of selecting risky items was studied and delivered. Through research and discussions with the client companies, it is confirmed that the most suitable factors for identifying global supply risky items are 'import size', 'import dependence', and 'trend abnormality'. The meaning of each indicator is introduced, and risky items are selected using export/import data until October 2022. Through this paper, it is expected that countries and companies will be able to identify global supply risky items in advance and prepare for risks in the new normal situation: the economic situation caused by infectious diseases such as the COVID-19 pandemic; and the export/import regulation due to geopolitical problems. The client company will include in his report, the method presented in this paper and the risky items selected by the method.

• International Journal of Knowledge Content Development & Technology
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• v.12 no.4
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• pp.41-65
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• 2022

This study would understand the overall perception of our society about public libraries, analyzing the texts related to public libraries, utilizing the semantic connection network & sentiment analysis. For this purpose, this study collected data from the last five years with keywords, 'Library' and 'Lifelong Learning Center' from January 1, 2016 through November 30, 2020 through the blogs and cafés of major domestic portal sites. With the collected data, text mining, centrality of keywords, network structure, structural equipotentiality, and sensitivity analyses were conducted. As a result of the analysis, First, 'reading' and 'book' were identified as representative keywords that form the social perception of public libraries. Second, it turned out that there were keywords related to the use of the library and the untact service due to the recent spread of COVID-19. Third, in seeking a plan for the development of public libraries through the keywords drawn to have positive meanings, it is necessary to create continuous services that can form a new image of the library, breaking away from the existing fixed role and image of the library and increase the convenience of use. Fourth, facilities and facilities for library services were recognized from a neutral point of view. Fifth, the spread of infectious diseases, social distancing, and temporary closure and closure of libraries are negatively related to public libraries, and awareness of librarians has been identified as negative keywords.

• Journal of Korean Academy of Rural Health Nursing
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• v.18 no.1
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• pp.40-48
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• 2023

Purpose: This study is a descriptive research that analyzes the current status of education for COVID-19 response tasks and factors affecting work fatigue of primary health care practitioners who have experience in dispatching to respond to COVID-19. Methods: This study collected data through an online survey from September 21 to 29, 2022, targeting 193 primary health care practitioners. The data were analyzed by frequency, percentage, mean, standard deviation, and logistic regression analysis using the SPSS 25.0 program. Results: 74.1% of the study subjects were dispatched without receiving disaster medical training to respond to COVID-19. 59.6% of the study subjects' work fatigue was above the level of being very tired. The factors that affect the work fatigue of the subjects were disaster participation experience, work intensity, compensation regulations, compensation satisfaction, and understanding of COVID-19 guidelines. Conclusion: Based on the results of this study, an educational program for systematic disaster response and preparation for primary health care practitioners in charge of public health care should be developed to efficiently cope with the occurrence of new infectious diseases in the future.

• Clinical and Experimental Vaccine Research
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• v.12 no.3
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• pp.193-208
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• 2023

One of the most significant medical advancements in human history is the development of vaccines. Progress in vaccine development has always been greatly influenced by scientific human innovation. The main objective of vaccine development would be to acquire sufficient evidence of vaccine effectiveness, immunogenicity, safety, and/or quality to support requests for marketing approval. Vaccines are biological products that enhance the body's defenses against infectious diseases. From the first smallpox vaccine to the latest notable coronavirus disease 2019 nasal vaccine, India has come a long way. The development of numerous vaccines, driven by scientific innovation and advancement, combined with researcher's knowledge, has helped to reduce the global burden of disease and mortality rates. The Drugs and Cosmetics Rules of 1945 and the New Drugs and Clinical Trials Rules of 2019 specify the requirements and guidelines for CMC (chemistry, manufacturing, and controls) for all manufactured and imported vaccines, including those against coronavirus infections. This article provides an overview of the regulation pertaining to the development process, registration, and approval procedures for vaccines, particularly in India, along with their brief history.