• Title/Summary/Keyword: method validation #5

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Validation of a Needs Assessment Tool for Case Management in Korean Medical Aid Beneficiaries (의료급여수급권자의 사례관리 요구측정도구의 타당도와 신뢰도 검증)

  • Ahn, Yang-Heui;Kim, Eui-Sook;Ham, Ok-Kyung;Kim, Soo-Hyun;Kim, Soon-Ok;Song, Myung-Kyung
    • Journal of Korean Academy of Nursing
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    • v.42 no.4
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    • pp.549-558
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    • 2012
  • Purpose: The purpose of this study was to validate the Needs Assessment Tool for Case Management (NATCM) for use with Korean medical aid beneficiaries. Methods: Psychometric testing was performed with a sample of 645 Korean medical aid beneficiaries, which included 41 beneficiaries who were selected using proportional sampling method, to examine intraclass correlation coefficients (ICC). Data were evaluated using item analyses, exploratory factor analysis (EFA), confirmatory factor analysis (CFA), Cronbach's alpha, and ICC. Results: Through psychometric testing the final version of NATCM was found to consist of two subscales: 1) Appropriateness of Health Care Utilization (5 items) and 2) Self Care Ability (6 items). The two subscale model was validated by CFA (RMSEA=.08, GFI=.97, and CFI=.93). Internal consistency measured by Cronbach's alpha was .82, and subscale reliability ranged from .79 to .84. The ICC of the NATCM between case managers was .73 and between case managers and health care professionals. .82. Conclusion: This study suggests that the final version of NATCM is a brief, reliable, and valid instrument to measure needs of Korean medical aid beneficiaries. Therefore, the NATCM can be effectively utilized as an important needs assessment as well as outcome evaluation tool for case management programs in Korea.

Efficiency calibration of a coaxial HPGe detector-Marinelli beaker geometry using an 152Eu source prepared in epoxy matrix and its validation by efficiency transfer method

  • Yucel, Haluk;Zumrut, Senem;Nartturk, Recep Bora;Gedik, Gizem
    • Nuclear Engineering and Technology
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    • v.51 no.2
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    • pp.526-532
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    • 2019
  • In this study, an in-house $^{152}Eu$ calibration source was produced from a custom epoxy matrix with a density of ${\rho}=1.14g\;cm^{-3}$, which is chemically stable and durable form after its solidification. The homogeneity of $^{152}Eu$ in matrix was obtained better than 98%. For a Marinelli beaker geometry, an efficiency calibration procedure was applied to a n-type, coaxial, 78.5% relative efficient HPGe detector in the energy range of 121.7-1408.0 keV by using in-house $^{152}Eu$ calibration source. Then the measured efficiencies for Marinelli geometry were compared with the results calculated by MEFFTRAN and ANGLE softwares for the validation. Although MEFFTRAN and ANGLE have two different efficiency transfer algorithms to calculate the efficiencies, they usually need to use a reliable and accurate reference efficiency values as input data. Hence, reference efficiency values were obtained experimentally from a multinuclide standard source for the same detector-Marinelli geometry. In the present source characterization, the corrections required for self-absorption and true coincidence summing effects for $^{152}Eu$ gamma-rays were also obtained for a such close counting geometry condition. The experimental results confirmed the validity of efficiency calculations obtained by MEFFTRAN and ANGLE softwares that are calculation tools.

Predicting the mortality of pneumonia patients visiting the emergency department through machine learning (기계학습모델을 통한 응급실 폐렴환자의 사망예측 모델과 기존 예측 모델의 비교)

  • Bae, Yeol;Moon, Hyung Ki;Kim, Soo Hyun
    • Journal of The Korean Society of Emergency Medicine
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    • v.29 no.5
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    • pp.455-464
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    • 2018
  • Objective: Machine learning is not yet widely used in the medical field. Therefore, this study was conducted to compare the performance of preexisting severity prediction models and machine learning based models (random forest [RF], gradient boosting [GB]) for mortality prediction in pneumonia patients. Methods: We retrospectively collected data from patients who visited the emergency department of a tertiary training hospital in Seoul, Korea from January to March of 2015. The Pneumonia Severity Index (PSI) and Sequential Organ Failure Assessment (SOFA) scores were calculated for both groups and the area under the curve (AUC) for mortality prediction was computed. For the RF and GB models, data were divided into a test set and a validation set by the random split method. The training set was learned in RF and GB models and the AUC was obtained from the validation set. The mean AUC was compared with the other two AUCs. Results: Of the 536 investigated patients, 395 were enrolled and 41 of them died. The AUC values of PSI and SOFA scores were 0.799 (0.737-0.862) and 0.865 (0.811-0.918), respectively. The mean AUC values obtained by the RF and GB models were 0.928 (0.899-0.957) and 0.919 (0.886-0.952), respectively. There were significant differences between preexisting severity prediction models and machine learning based models (P<0.001). Conclusion: Classification through machine learning may help predict the mortality of pneumonia patients visiting the emergency department.

Life Risk Assessment of Landslide Disaster in Jinbu Area Using Logistic Regression Model (로지스틱 회귀분석모델을 활용한 평창군 진부 지역의 산사태 재해의 인명 위험 평가)

  • Rahnuma, Bintae Rashid Urmi;Al, Mamun;Jang, Dong-Ho
    • Journal of The Geomorphological Association of Korea
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    • v.27 no.2
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    • pp.65-80
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    • 2020
  • This paper deals with risk assessment of life in a landslide-prone area by a GIS-based modeling method. Landslide susceptibility maps can provide a probability of landslide prone areas to mitigate or proper control this problems and to take any development plan and disaster management. A landslide inventory map of the study area was prepared based on past historical information and aerial photography analysis. A total of 550 landslides have been counted at the whole study area. The extracted landslides were randomly selected and divided into two different groups, 50% of the landslides were used for model calibration and the other were used for validation purpose. Eleven causative factors (continuous and thematic) such as slope, aspect, curvature, topographic wetness index, elevation, forest type, forest crown density, geology, land-use, soil drainage, and soil texture were used in hazard analysis. The correlation between landslides and these factors, pixels were divided into several classes and frequency ratio was also extracted. Eventually, a landslide susceptibility map was constructed using a logistic regression model based on entire events. Moreover, the landslide susceptibility map was plotted with a receiver operating characteristic (ROC) curve and calculated the area under the curve (AUC) and tried to extract a success rate curve. Based on the results, logistic regression produced an 85.18% accuracy, so we believed that the model was reliable and acceptable for the landslide susceptibility analysis on the study area. In addition, for risk assessment, vulnerability scale were added for social thematic data layer. The study area predictive landslide affected pixels 2,000 and 5,000 were also calculated for making a probability table. In final calculation, the 2,000 predictive landslide affected pixels were assumed to run. The total population causalities were estimated as 7.75 person that was relatively close to the actual number published in Korean Annual Disaster Report, 2006.

A Study on Calculation of Cross-Section Properties for Composite Rotor Blades Using Finite Element Method (유한요소법 기반의 복합재료 블레이드 단면 특성치 계산에 관한 연구)

  • Park, Il-Ju;Jung, Sung-Nam;Cho, Jin-Yeon;Kim, Do-Hyung
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.37 no.5
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    • pp.442-449
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    • 2009
  • A two-dimensional cross-section analysis program based on the finite element method has been developed for composite blades with solid, thin-walled and compound cross-sections. The weighted-modulus method is introduced to determine the laminated composite material properties. The shear center and the torsion constant for any given section are calculated according to the Trefftz' definition and the St. Venant torsion theory, respectively. The singular value problem of cross-section stiffness properties faced during the section analysis has been solved by performing an eigenvalue analysis to remove the rigid body mode. Numerical results showing the accuracy of the program obtained for stiffness, offset and inertia properties are compared in this analysis. The current analysis results are validated with those obtained by commercial software and published data available in the literature and a good correlation has generally been achieved through a series of validation study.

Rapid and Sensitive Analysis of Valproic Acid in Human Red Blood Cell by LC-MS/MS

  • Han, Song-Hee;Kim, Yun-Jeong;Jeon, Ji-Young;Hwang, Min-Ho;Im, Yong-Jin;Jeong, Jin-A;Lee, Chang-Seop;Chae, Soo-Wan;Kim, Min-Gul
    • Bulletin of the Korean Chemical Society
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    • v.33 no.5
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    • pp.1681-1685
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    • 2012
  • A sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) method was developed to determine valproic acid in human red blood cell (RBC). It is important to measure the drug concentration of the RBC as well as that of the plasma because of drug partitioning for pharmacokinetic and pharmacodynamic study. The method was linear over the dynamic range of 1-100 ${\mu}g$/mL with a correlation coefficient $r$ = 0.9997. The linearity of this method was established from 1 to 100 ${\mu}g$/mL for valproic acid in red blood cell with accuracy and precision within 15% at all concentrations. The intra-run and inter-run assay accuracy and coefficient of variations are all within 15% for all QC samples prepared in plasma and red blood human samples. Then, valproic acid amount by protein precipitation in plasma was quantified by LC-MS/MS mass spectrometry. The distribution ratio of VPA in RBC and plasma was analyzed by clinical samples. Based on measurement of the valproic acid in human red blood cell, this method has been applied to clinical research for study of distribution ratio of valproic acid in blood.

Accurate Measurement of Arsenic in Laver by Gravimetric Standard Addition Method Combined with High Resolution Inductively Coupled Plasma Mass Spectrometry

  • Lee, Kyoung-Seok;Kim, Hyeon-Ji;Yim, Yong-Hyeon;Kim, Jeongkwon;Hwang, Euijin
    • Mass Spectrometry Letters
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    • v.5 no.2
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    • pp.57-61
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    • 2014
  • A gravimetric standard addition method combined with internal standard calibration has been successfully developed for the accurate analysis of total arsenic in a laver candidate reference material. A model equation for the gravimetric standard addition approach using an internal standard was derived to determine arsenic content in samples. Handlings of samples, As standard and internal standard were carried out gravimetrically to avoid larger uncertainty and variability involved in the volumetric preparation. Germanium was selected as the internal standard because of its close mass to the arsenic to minimize mass-dependent bias in mass spectrometer. The ion signal ratios of $^{75}As^+$ to $^{72}Ge^+$ (or $^{73}Ge^+$) were measured in high resolution mode ($R{\geq}10,000$) to separate potential isobaric interferences by high resolution ICP/MS. For method validation, the developed method was applied to the analysis of arsenic content in the NMIJ 7402-a codfish certified reference material (CRM) and the result was $37.07mg{\cdot}kg^{-1}{\pm}0.45mg{\cdot}kg^{-1}$ which is in good agreement with the certified value, $36.7mg{\cdot}kg^{-1}{\pm}1.8mg{\cdot}kg^{-1}$. Finally, the certified value of the total arsenic in the candidate laver CRM was determined to be $47.15mg{\cdot}kg^{-1}{\pm}1.32mg{\cdot}kg^{-1}$ (k = 2.8 for 95% confidence level) which is an excellent result for arsenic measurement with only 2.8 % of relative expanded uncertainty.

Study on Performance-based Evaluation Method for Rock Slopes : Deduction of Weight and Validation - Based on the AHP method and Correlation Analysis - (암반비탈면의 성능기반 평가기법 연구 : 가중치 도출 및 검증 - AHP 기법과 상관분석을 중심으로 -)

  • Lee, Jong Gun;Heo, In Young;Kang, Chang Kyu;Ryu, Ho Sang;Chang, Buhm Soo
    • Tunnel and Underground Space
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    • v.26 no.5
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    • pp.431-440
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    • 2016
  • This study aims to suggest the detailed evaluation criteria based on performances for rock slopes. Using the previous research result, final evaluation items are proposed considering characteristics and similarities of each evaluation item. Weight for each evaluation item is deducted using AHP method, verification for suggested evaluation criteria is conducted based on correlation analysis. The research results as follows. All evaluation items have a high statistical correlation with final evaluation result(safety rating). Especially, items of the "rockfall", "ground deformation", "discontinuity characteristic", "instable lithology" were shown the highest in relative correlation coefficient(R), It is judged that items and weight presented in this study well reflect characteristics of rock slopes.

A Design of Predistortion HPA using Frequency Up-Conversion Mixing Operation (주파수 상향 변환을 이용한 전치왜곡 전력 증폭기 설계)

  • Jeong, Yong-Chae;Kim, Young;Kim, Chul-Dong
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.15 no.5
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    • pp.480-485
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    • 2004
  • In this paper, a new predistortion linearizing method using frequency up-conversion operation of mixer is proposed. This linearizing method doesn't require any additional signal sources in spite of frequency up-conversion mixing operation. This method extracts the 2nd low frequency intermodulation distortion signal from input signals and uses the extracted 2nd low frequency intermodulation distortion signal as mixing signal source. To show validation of the proposed predistortion method, we made K-PCS power amplifier. On 2-tone signals amplification process, the (C/I) ratio of amplifier is improved 26 ㏈ (@Po=22 ㏈m/tone), where two tones are 1.8544 ㎓ and 1.8556 ㎓, respectively. And (C/I) ratio is improved more than to 20 ㏈ for 17 ㏈ output signal dynamic range. On IS-95A CDMA 1FA amplification process, the improvements of adjacent channel power ratio(ACPR) are 10.8 ㏈ and 6.4 ㏈ at ${\pm}$885 ㎑ and ${\pm}$1.25 ㎒ offset points, respectively.

Development of An Unsteady Navier-Stokes Solver using Implicit Dual Time Stepping Method and DADI Scheme (내재적 이중시간 전진기법과 DADI 기법을 이용한 비정상 Navier-Stokes 코드개발)

  • Lee, Eun-Seok
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.33 no.9
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    • pp.34-40
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    • 2005
  • In present study, a two dimensional unsteady Navier-Stokes solver has been developed using the Diagonalized ADI (DADI) method and implicit dual time stepping method. The jacobian matrices in steady state Navier-Stokes equations are introduced from inviscid flux terms. The implicit treatment of artificial dissipation terms results in a block penta-diagonal matrix system and it becomes a scalar penta-diagonal matrix by diagonalization. In steady state equations about fictitious time, a new residual including a real time derivative term is introduced. From a converged solution about fictitious time, a real time unsteady solution can be obtained, which is called 'implicit dual time stepping method'. For code validation, an oscillating flat plate, a regular Karman vortices past a circular cylinder and shock buffeting around a bicircular airfoil problems are numerically solved. And they are compared with a theoretical solution, experiments and other researcher's computations.