• Biomolecules & Therapeutics
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• v.18 no.1
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• pp.56-64
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• 2010

Pentoxifylline (PTX) has been used for the local reduction of fat tissue in the clinical setting. However, its safety and efficacy have not been proven. The aim of this study was to evaluate the effects of PTX on cell lines established from fat tissue. Newly cultured human preadipocytes and adipocytes from subcutaneous abdominal fat in addition to purchased human lung fibroblasts and keratinocytes were treated with PTX at different concentrations. Cell viability was determined using the Cell counting kit (CCK)-8 assay and lipolysis was evaluated using an Elisa kit. DNA fragmentation, Western blot analysis, Hoechst and Propidium Iodide (PI) staining and fluorescence activated cell scanning analysis were performed to confirm apoptosis. The viability of adipocytes, preadipocytes, keratinocytes and fibroblasts was markedly decreased at concentrations of PTX above 20 mM. Apoptosis was induced at concentrations of PTX over 40 mM in all cell lines. Lipolysis was increased by 60% at concentrations of PTX of 20 mM compared to the control. In conclusion, the results of this study showed that 20 mM of PTX induced lipolysis. At concentrations over 20 mM, PTX reduced the viability of all cells studied including: adipocytes, preadipocytes, fibroblasts and keratinocytes, in a non-specific manner.

• Proceedings of KHEA Conference
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• 1997.07a
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• pp.58-58
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• 1997

• Journal of Family Resource Management and Policy Review
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• v.8 no.1
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• pp.101-116
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• 2004

This study analyze using pattern of the Korean elderly leisure time to know their leisure lifestyle. In order to do this study, we analysed the time use dairy which were collected by Korean National Statistical Office in 1999 and analysis of data was done through mean of time, percentage of acting people hourly. The result of this study were as follows : 1) The elderly spend leisure time average 6 hours 34 minute in a day and enjoy leisure activities from A.M. 11:00 to P.M. 12:00 and from P.M. 8:00 to P.M:. 10:00 mainly. 2) The elderly spend leisure time for acquaintance, using mass media, sports leisure activity and dilettante life. Especially the elderly associate with more others than their family, use more TV than others and spend time for break and amusement as dilettante life.

• Communications for Statistical Applications and Methods
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• v.24 no.1
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• pp.43-65
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• 2017

We propose a flexible cure rate survival model by assuming that the number of competing causes of the event of interest has the Poisson distribution and the time for the event follows the gamma-G family of distributions. The extended family of gamma-G failure-time models with long-term survivors is flexible enough to include many commonly used failure-time distributions as special cases. We consider a frequentist analysis for parameter estimation and derive appropriate matrices to assess local influence on the parameters. Further, various simulations are performed for different parameter settings, sample sizes and censoring percentages. We illustrate the performance of the proposed regression model by means of a data set from the medical area (gastric cancer).

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.10
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• pp.2181-2187
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• 2011

In this paper, a family of binary sequences generated by GMW sequences and No sequences is introduced and analyzed. Each sequence within a family has period $N=2^n-1$, n=2m and there are $2^m$ sequences within that family. We obtain auto and cross-correlation values and linear span of the synthesized sequence.

• Communications of the Korean Mathematical Society
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• v.38 no.3
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• pp.787-805
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• 2023

Let (Ω, µ) be a measure space and {τ_α}_α∈Ω be a normalized continuous Bessel family for a finite dimensional Hilbert space 𝓗 of dimension d. If the diagonal ∆ := {(α, α) : α ∈ Ω} is measurable in the measure space Ω × Ω, then we show that $$\sup\limits_{{\alpha},{\beta}{\in}{\Omega},{\alpha}{\neq}{\beta}}\,{\mid}{\langle}{\tau}_{\alpha},\,{\tau}_{\beta}{\rangle}{\mid}^{2m}\,{\geq}\,{\frac{1}{({\mu}{\times}{\mu})(({\Omega}{\times}{\Omega}{\backslash}{\Delta})}\;\[\frac{{\mu}({\Omega})^2}{\({d+m-1 \atop m}\)}-({\mu}{\times}{\mu})({\Delta})\],\;{\forall}m{\in}{\mathbb{N}}.$$ This improves 48 years old celebrated result of Welch [41]. We introduce the notions of continuous cross correlation and frame potential of Bessel family and give applications of continuous Welch bounds to these concepts. We also introduce the notion of continuous Grassmannian frames.

• Communications of the Korean Mathematical Society
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• v.9 no.4
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• pp.905-915
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• 1994

Let $M_g$ be the moduli space of isomorphism classes of genus g smooth curves. It is a quasi-projective variety of dimension 3g - 3, when $g > 2$. It is known that a complete subvariety of $M_g$ has dimension $< g-1 [D]$. In general it is not known whether this bound is rigid. For example, it is not known whether $M_4$ has a complete surface in it. But one knows that there is a complete curve through any given finite points [H]. Recently, an explicit example of a complete curve in moduli space is given in [G-H]. In [G-H] they constructed a complete curve of $M_3$ as an intersection of five hypersurfaces of the Satake compactification of $M_3$. One way to get a complete curve of $M_3$ is to find a complete one dimensional family $p : X \to B$ of plane quartics which gives a nontrivial morphism from the base space B to the moduli space $M_3$. This is because every non-hyperelliptic smooth curve of genus three can be realized as a nonsingular plane quartic and vice versa. This paper has come out from the effort to find such a complete family of plane quartics. Since nonsingular quartics form an affine space some fibers of p must be singular ones. In this paper, due to the semistable reduction theorem [M], we search singular plane quartics which can occur as singular fibers of the family above. We first list all distinct plane quartics in terms of singularities.

• Research in Community and Public Health Nursing
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• v.14 no.1
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• pp.120-131
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• 2003

Purpose: to investigate nursing service needs of dementia caregivers in the community, and, also to provide basic data that is helpful in developing nursing intervention for them. Method: MMSE-K exam was administered on 15,216 men more than 65years old who live in Gu, Seoul city, and the subject of this study were caregivers of 792 demented elderly who were below 20 points in the MMSE-K exam. Result: Total score of nursing service needs of family appeared lower than average. By specific area, information nursing needs was the highest(M=3.29), and therapeutic nursing needs (M=3.31), welfare service nursing needs(M=3.32), emotional support nursing needs (M=3.34) followed in order. The factors which increased the total score of nursing service needs of dementia caregivers as general and physical characteristics were man (p=.04), lower ADL (p=.00) and IADL(p=.00), longer length of sick days(p=.01), having diseases(p=.03), decline of cognition(p=.00), existence of dementia symptom(p=.00). And. high economic status(p=.03), good caring attitude(p=.00) were family characteristics which increased the nursing service needs of caregivers. As predicting variables dementia symptom (10.4%), caring attitude(1.9%), existence of economic activity (1.5%), and length of sick days(1.2%) exhibited explanation power in order. Conclusion: In future, active intervention methods that correspond to family nursing service needs have to be developed, and it is also needed to develop nursing intervention strategy on specific problem with dementia problematic behavior, exercise etc.. Also, it is needed to do research on the caring attitude of dementia family because active caring attitude of family was significant influencing factor on nursing service needs of family.

• Korean Journal of Human Ecology
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• v.5 no.2
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• pp.17-35
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• 1996

The purpose of this study was to develope Premarial Sexual Education Program. This program was based on survey(466 data used) for the need of PSEP. The result were as followings: 1. The need of sex education was higher(92.9%) and the participation of this PSEP was 80.4%, so this program was systemic structure. 2. Their premarital sexual values were more permissive(52.2%) than the past. But women thought tha female would be vergin(27.1%) their inter course experience rate was 33.4% and Age of experience was under 23 year olds. 3. The unmarried persns wanted that PSEP was consisted of 10 sub themes : (1) pregnancy and child-birth(mean=4.4/5) (2) contraception and family planning(m=4.3) (3) sexual morality and sexual value(m=4.2) (4) sexual healthy family (m=4.1) (5) sexual open communication(m=4.1) (6) venereal disease and coping stratiges(m=4.0) (7) sex role learning(m=3.9) (8) sexual physiology(m=3.8) (9) premarital sex and unwed mother(m=3.7) (10) adultery and society(m=3.6) 4. They want that group meeting would be every Wensday or Friday evening and the required time is two hours. The instruction methods are expected lecture, discussion or seminar and viewing video tapes. 5. So PSEP was consist of 10 sub-themes: (1) orientation and self-disclosure(test, lecture, game) (2) sexual physiology(video tape, lecture) (3) pregnancy and child birth(lecture, video tape) (4) contraceptive methods and family planning(lecture, video tape, test, discussion) (5) sex role learning(test, lecture, role-play) (6) venereal disease and coping stratiges(lecture, video tape) (7) premarital sex and incest(cause study, lecture) (8) sex morality and sex value(seminars, lecture) (9) sexual open communication(seminars) (10) sexual healthy family(lecture, seminars)

• Journal of Korean Academy of Fundamentals of Nursing
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• v.4 no.2
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• pp.175-192
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• 1997

The purpose of this study was to identify the care needs of family-caregivers to the patients with stroke. Subjects were 115 family-caregivers caring for the patients while they were in-patients or out-patients with stroke in two general hospitals and one oriental medicine hospital located in Seoul and Kwang-Ju. The instrument used for this study was made by the researcher on the basis of results of literature review and interviews with family-caregivers, composed of 35 items. Internal validity by calculation of cronbach's alpha with data of respondents was 0.91, which was regarded as high. The Data were analyzed by SAS program, with percentage, mean, t-test, and ANOVA. Factor structures of care needs of family-caregivers were elicited by factor analysis(PCA, Varimax rotation). Datum collection had been from July 1 to August 14, 1997. The results of this study were as follows : 1. The mean score of the sum of the care needs of family-caregivers was 3.96 and the highest-mean item was 'need for immediate care(M=4.77)', and the lowest-mean item was 'need for chaplian's visit (M=2.82)'. 2. Care needs of the family-caregivers were : Need to be informed of the disease, treatment and care ; need of education and assistance related to physical functional level ; need of social support and consultation ; need of management of nursing problem related to immobility ; need of appreciation ; need of the way to communicate with patients ; need of immediate care and help. The highest mean factor was the 'need for immediate care and help(M=4.74)', and the lowest mean factor was the 'need of appreciation(M=3.58)'. 3. The variables influencing the degree of care needs perceived by family-caregivers to the patients with stroke were as follows : There were significant differences between need to be informed of the disease, treatment and care and general characteristic factors, which were family caregiver's sex (p=.0178), caring period(p=.0223) and patient's suffering period(p=.0244). There were significant differences between need of education and assistance related to physical functional level and general characteristic factors, which were patient's paralysis(p=.0177), patient's ADL dependency(p=.0032). There were significant differences between need of social support and consultation and general characteristic factors, which were family caregiver's sex(p=.0055), occupation(p=.0159), religion(p=.0093) and patient's sex(p=.0134). There was significant difference in the degree of need of management of nursing problem related to immobility, according to the patient's ADL dependency(p=.0493). There were significant differences between need of appreciation and general characteristic factors, which were family caregiver's age(p=.0107), sex(p=.0133), and patient's age(p=.0338). There were significant differences between need of the way to communicate with patient and general characteristic factors, which were patient's paralysis(p=.0002) and aphasia(p=.0001). There were significant differences between need of immediate care and help and general characteristic factors, which were family caregiver's caring period(p=.0162) and patient's suffering period(p=.0116). 4. The mean score of patient's ADL dependency was 3. 38 and the highest-mean item was 'ascending and descending stairs(M=4.12)', and the lowest-mean item was 'drinking(M=2.60)'. There was no significant difference in the degrees of care needs related to the patient's ADL dependency. 5. The highest information source of family-caregivers was from the doctors about the disease, treatment and care(26.1%). The second highest one was from mass media(20.8%), and the third one was from the nurses. The above findings may be used as the basic data to seek more efficient way of elevating nursing practice and quality for family-caregivers to the patients with stroke.