• Molecules and Cells
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• 제43권8호
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• pp.749-762
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• 2020

The migration, dedifferentiation, and proliferation of vascular smooth muscle cells (VSMCs) are responsible for intimal hyperplasia, but the mechanism of this process has not been elucidated. WD repeat domain 1 (WDR1) promotes actin-depolymerizing factor (ADF)/cofilin-mediated depolymerization of actin filaments (F-actin). The role of WDR1 in neointima formation and progression is still unknown. A model of intimal thickening was constructed by ligating the left common carotid artery in Wdr1 deletion mice, and H&E staining showed that Wdr1 deficiency significantly inhibits neointima formation. We also report that STAT3 promotes the proliferation and migration of VSMCs by directly promoting WDR1 transcription. Mechanistically, we clarified that WDR1 promotes the proliferation and migration of VSMCs and neointima formation is regulated by the activation of the JAK2/STAT3/WDR1 axis.

• Safety and Health at Work
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• 제7권2호
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• pp.166-170
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• 2016

A brief emergency planning educational presentation was taught during work hours to a convenience sample of employees of various workplaces in Northern Missouri, USA. Participants were familiarized with details about how an emergency plan is prepared by management and implemented by management-employee crisis management teams - focusing on both employee and management roles. They then applied the presentation information to assess their own organization's emergency preparedness level. Participants possessed significantly (p < 0.05) higher perceptions of their organization's level of emergency preparedness than non-participants. It is recommended that an assessment of organizational preparedness level supplement emergency planning educational presentations in order to immediately apply the material covered and encourage employees to become more involved in their organization's emergency planning and response. Educational strategies that involve management-employee collaboration in activities tailored to each workplace's operations and risk level for emergencies should be implemented.

• 보건행정학회지
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• 제29권4호
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• pp.422-430
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• 2019

Background: This study aimed to demonstrate the association between the education level of parents and adolescent depression feeling. Methods: We used the chi-square test and the multiple logistic regression model to analyze the data of the "Korean Youth Health Behavior Survey in 2018" (n=43,220) conducted by the Korea Centers for Disease Control and Prevention. Results: As a result of the analysis, a group whose parents' education level is 'above the university graduation (including the graduation of the college)' had statistically significant experience of depression than a group whose parents' education level is 'high school graduation.' Conclusion: When preparing a policy on adolescent depression feeling, we need to consider the association between the education level of parents and adolescent depression feeling. Especially, a higher level of education of parents needs attention and management to foster positive mental health rather than excessive academic pressure, especially in the parent-child relationship of the same gender.

• 대한치위생과학회지
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• 제3권1호
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• pp.45-50
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• 2020

A total of nine oral health educators for 17 persons with developmental disabilities conducted oral health education once a week for four weeks. The oral health educators provided oral health knowledge education and individual toothbrushing teachings. The developmentally disabled people in their 20s and 30s conducted oral health education without a guardian. Ten people who completed all the four pieces of training had no significant improvement in the toothbrushing method and the recommended number of toothbrushing sessions a day, as well as a lack of growth in oral health knowledge. However, 58.8% of the individuals expressed satisfaction with the oral health education program, whereas, 52.9% expressed the desire for a re-education. Although the ratio of teachers to students was 1:2, and the oral health education conducted four times, it was insufficient to promote a successful oral health behavior or knowledge for people with developmental disabilities. Therefore, as a suggestion, oral health education for people with developmental disabilities ought to proceed with their guardians to promote the success of the training.

• Safety and Health at Work
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• 제14권3호
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• pp.340-346
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• 2023

Background: Truck driving is a highly sedentary occupation that places workers at risk for chronic health conditions, such as obesity and high blood pressure. The primary purpose of this study was to objectively describe truck drivers' typical physical activity (PA) patterns. Methods: We used ~7-10-day baseline PA actigraphy data samples from drivers in the Safety & Health Involvement For Truckers (SHIFT) study (n = 394). Driver PA patterns (e.g., average number of ≥10 minute Freedson bouts per week, time in bouts, and common days/times for PA) were summarized with descriptive analyses. We also compared objective accelerometer data to self-reports. Results: Drivers' weekly PA averaged 14.4 minutes (SD = 37.0), and most PA occurred between 5-6 pm on Tuesdays and Wednesdays. Drivers overestimated self-reported weekly exercise by over 60 min/week compared to accelerometer data. Conclusion: Our results suggest that objective PA assessment may be warranted over self-report when possible, and timing may be key in future PA intervention work with truck drivers.

• BMB Reports
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• 제42권2호
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• pp.81-85
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• 2009

Early and accurate detection of drug resistant Mycobacterium tuberculosis can improve both the treatment outcome and public health control of tuberculosis. A number of molecular-based techniques have been developed including ones using probe molecules that target drug resistance-related mutations. Although these techniques are highly specific and sensitive, mixed signals can be obtained when the drug resistant isolates are mixed with drug susceptible isolates. In order to overcome this problem, we developed a new drug susceptibility test (DST) for one of the most effective anti-tuberculosis drug, isoniazid. This technique employed a microplate hybridization assay that quantified signals from each probe molecule, and was evaluated using clinical isolates. The evaluation analysis clearly showed that the microplate hybridization assay was an accurate and rapid method that overcame the limitations of DST based on conventional molecular techniques.

• 센서학회지
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• 제20권2호
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• pp.96-101
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• 2011

In this study, we fabricated a fiber-optic phantom dosimeter by arraying square type of plastic optical fibers in a PMMA phantom for measuring relative depth doses of therapeutic photon beams. To minimize the cross-talk between fiber-optic dosimeters, we selected appropriate septum by measuring leaked scintillating lights according to the various kinds of septa. In addition, we measured percentage depth doses of 6, 15 MV photon beams using a fiber-optic phantom dosimeter.

• 한국보건간호학회지
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• 제28권2호
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• pp.211-227
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• 2014

Purpose: The purpose of this study was to compare health literacy levels of Asian immigrant women and factors associated with health literacy focusing on Korean-Chinese and other Asian immigrants in Korea. Methods: Data were drawn from 258 immigrant women, comprising 56 Korean-Chinese and 202 other immigrants from the Philippines, Vietnam, Japan, Cambodia, Thailand, Uzbekistan, Taiwan, and Han-Chinese. The Rapid Estimate of Adult Literacy in Medicine - Short Form (REALM-SF) was used to assess health literacy, which consisted of seven medical words in Korean (behavior, exercise, menopause, rectal, antibiotics, anemia, and jaundice). Data analysis was performed using descriptive statistics, t-test, ANOVA with $Sch{\acute{e}}ffe$ post hoc test, and hierarchical regression. Results: Korean-Chinese women showed significantly higher levels of health literacy ($M=6.41{\pm}1.07$), compared to their other immigrant counterparts ($M=4.55{\pm}2.15$). While Korean-Chinese women with longer time since immigration (p=.048) reported higher health literacy, for other immigrants, those living with children (p<.001), longer time since immigration (p=.011), and greater Korean language proficiency (p=.004) showed an association with higher health literacy. Conclusion: When providing health care services and health education, health care professionals should consider differences in levels of health literacy and factors associated with health literacy among Korean Chinese and other immigrants.

• 대한치과기공학회지
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• 제33권4호
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• pp.495-503
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• 2011

Purpose: The purpose of this study was to obtain data that can be utilized in the planning of oral health education plan, by surveying the correlation between oral health knowledge, attitude, and behavior among high grade students elementary school in some regions of the metropolitan. Methods: The subject of this study through the survey of the recognition of the oral health, a questionnaire survey was conducted for 548 male and female students who were in the 4th, 5th, 6th grade of elementary school in some regions of the metropolitan. Statistical analysis was conducted using the SPSS 12.0 with t-test, ANOVA, and correlation. Results: Knowledge of oral health was very high. Correct attitudes and positive behavior were indicated. There was a significant difference in oral health knowledge according to school year and parents' dental condition(P<.05). The student one recording oral health behavior degree where the oral health knowledge is high appears highly, considers statistically the difference which it was visible. Positive correlation was significantly observed among oral health knowledge, attitudes, and behavior. Especially, attitudes and toothbrush method were highly correlated(r=.853). Conclusion: Oral health program through the elementary school students and their parents for the development of proper oral health care education programs continue to be made should be considered.

• 한국축산식품학회지
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• 제29권5호
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• pp.599-611
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• 2009

This article concerns the labeling guideline for health benefits of livestock products. In recent years, livestock products with health benefits have emerged as a key market for livestock product industries. However, the current labeling regulation for functional foods severely prohibits livestock product industries from attaching most of the health benefits claims to the products. Also, manufacturers have some difficulties in labeling the health benefits of certain livestock products because of a lack of guidelines on health benefit claims for livestock products. Therefore, some livestock product industries and scientists have strongly demanded a revision of labeling regulation, Appended Chart No. 14 provided by Article 52 (2) of Enforcement Regulation of the Processing of Livestock Products Act, so they could mark the health benefits on their products. To support the 'revision of labeling regulation', the goals of this article were as follows; 1) to assess the current situation on nutrition labeling and nutrition claims on foods, 2) to determine the current situation on health claim regulatory systems used in foreign countries (CODEX, USA, Japan, EU, and Australia/New Zealand), 3) to assess the current situation on the health claim or health benefit claim regulations for functional foods, conventional foods, and livestock products in Korea, and 4) to determine the need for complement in health benefit claim for livestock products. In conclusion, guidelines for the use of health benefit claims on livestock products should be prepared as soon as possible and the guidelines should be viable and easy for manufacturers and control authorities to understand. Also, nutrient profiles should be developed to identify whether the livestock products are eligible to bear health benefit claims and to help consumers make the right choices.