• Title/Summary/Keyword: fine needle aspiration cytology

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A Case of Advanced Thyroid Insular Carcinoma with Invasion of the Sternum (흉골침습을 동반한 진행성 갑상선 섬암종(Insular Carcinoma) 1예)

  • Koh Yoon-Woo;Lee Seung-Won;Lee Jong-Dae;Kim Hyo-Jin;Kim Hee-Kyung
    • Korean Journal of Head & Neck Oncology
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    • v.21 no.2
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    • pp.178-182
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    • 2005
  • Insular carcinoma(poorly differentiated thyroid cancer) is defined as a aggressive, follicular-derived thyroid carcinoma with behavior intermediate between follicular/papillary and anaplastic carcinomas. It was described by Carcangiu in 1984, but its prognosis, classification and the origin is not yet clear. And preoperative fine needle aspiration cytology of insular carcinoma has not been satisfactory. We experienced a case of advanced thyroid insular carcinoma with invasion of the sternum. So we intend to present the case with a review of the related literatures.

A Case of a Huge Lateral Neck Mass as the Initial Presentation of Thyroid Carcinoma (거대한 단발성 측경부 종물로 나타난 전이성 갑상선암 1례)

  • Sohn Jin-Ho;Park Jae-Yul;Kim Kwang-Hoon;Sung Nak-Kwan
    • Korean Journal of Head & Neck Oncology
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    • v.15 no.1
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    • pp.89-91
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    • 1999
  • We experienced a case of the papillary thyroid carcinoma seen as a huge solid lateral neck mass. The mass grew very slowly over the period of 30years up to 10cm in diameter while relatively well sparing the surrounding tissues. Physical examinations, CT scan, and fine needle aspiration cytology did not reveal any strong suggestions for evidence of malignancy. But it was pathologically diagnosed as metastatic thyroid carcinoma by excisional biopsy. We emphasize that for a large solitary neck mass which persists for several decades, head and neck surgeons should always keep in mind the possibility of metastasis from the malignancy of thyroid gland.

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A Case of Embryonal Rhabdomyosarcoma at Left Parotid Gland in 8-Month-Old Infant (8개월 영아의 좌측 이하선 부위에서 발생한 배아형 횡문근육종 1예)

  • Cho, Minhyuk;Kim, Yeon Soo;Shin, YooSeob;Kim, Chul-Ho
    • Korean Journal of Head & Neck Oncology
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    • v.30 no.2
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    • pp.119-122
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    • 2014
  • Rhabdomyosarcoma is the most common sarcoma in children less than 15 years of age. Two major histological subtypes are embryonal and alveolar. Embryonal rhabdomyosarcoma is diagnosed by immunopathology and treatments require coordinated management plans that include surgery, chemotherapy, and usually radiotherapy. 8-month-old male infant visited with swelling in left parotid area. Computed tomography scan showed a heterogeneous mass in the left parotid area and the result of fine-needle aspiration cytology was suspicious malignancy. Left total parotidectomy was performed and CSF leakage was noted and repaired. Confirmed by positive reactions to desmin and myogenin, the diagnosis was embryonal rhabdomyosarcoma. On postoperative brain MRI, extension along the meninges was noted and for treatment, chemotherapy and gamma knife radiosurgery were done. Five years after initial surgical resection(3 years and 10 months after completion of chemotherapy and gamma knife radiosurgery), the child did not show any evidence of local recurrence or distant metastasis.

Lateral Neck Cyst as the Initial Presentation of Papillary Thyroid Carcinoma (측경부 낭종으로 발현된 유두상 갑상선암)

  • Park Cheong-Soo;Lee Won-Hung;Kim Choon-Kyu
    • Korean Journal of Head & Neck Oncology
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    • v.4 no.1
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    • pp.53-58
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    • 1988
  • We have experienced 3 cases of papillary carcinoma of the thyroid gland seen as lateral neck cyst, Usually cystic lesions of the neck have been considered as benign lesions from clinical viewpoint. The usual differential diagnosis includes branchial cleft cyst, cystic hygroma, dermoid cyst, cold abscess(tuberculous lymphadenitis) and cavitating squamous cell carcinoma. A lateral neck cyst as the sole presenting complaint of the papillary thyroid carcinoma is very rare. Preoperative diagnosis of lateral neck cyst is often diagnostic dilemma. Fine-needle aspiration cytology can be helpful in detecting the cancer cells and in demonstrating the nature of the fluid component of the lateral neck cyst. Presence of brown murky fluid from the aspirated fluid is highly suggestive of thyroid carcinoma. The thyroid scans and B-mode ultrasonography mayor may not be helpful to detect the primary focus of the thyroid gland. We suggest that a patient with a lateral neck cyst in adult age group should be considered to be a possibility of underlying thyroid carcinoma presanting as lateral neck cyst.

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Malignant Metastatic Insulinoma with Hypoglycemia in a Shih Tzu (Shih Tzu에서 저혈당증을 동반한 악성 전이성 인슐린종)

  • Jee Hyang;Joo Min-suk;Pakhrin Bidur;Hwang Cheol-yong;Kim Dae-Yong
    • Journal of Veterinary Clinics
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    • v.22 no.3
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    • pp.275-277
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    • 2005
  • A six year old female Shih Tzu was euthanized after having about 2 months history of weakness and convulsion with hypoglycemia. On ultrasonography, several masses in variable sizes were noted in the liver and fine needle aspiration cytology revealed probable neoplasm of pancreatic origin. On necropsy, numerous round firm tan nodules with central depression were noted in the liver and heart. Mesenteric lymph node was enlarged and fused with presumable pancreatic tissue. Based on the histopathology and immunohistochemistry, the tumor was confirmed as malignant metastatic insulinoma.

A Case of Anterior Mediastinal Mass Presenting with SVC Syndrome (상대정맥 증후군을 동반한 전종격동 종괴)

  • Park, Ik-Soo;Yoon, Ho-Joo;Shin, Dong-Ho;Park, Sung-Soo;Lee, Jung-Hee;Kim, Nam-Hoon;Lee, Jung-Dal
    • Tuberculosis and Respiratory Diseases
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    • v.41 no.6
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    • pp.676-679
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    • 1994
  • A 36-year-old man was studied because of signs and symptoms of superior vena caval syndrome. Chest computerized tomography showed $10{\times}8{\times}6$ cm sized lobulated anterior mediastinal mass, compressing superior vena cava. Fine needle aspiration cytology revealed seminoma. There was no detectable tumor mass in the testes. We report a case of primary mediastinal seminoma presenting with superior vena caval syndrome.

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An Unusual Case of Acute Lymphocytic Leukemia with Extramedullary Relapse Presenting as Parotid Enlargement (급성 림프구성 백혈병 환자에서 이하선 비대로 나타난 골수외 재발 1례)

  • Lee, Dong-Hee;Cho, Kwang-Jae
    • Korean Journal of Bronchoesophagology
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    • v.11 no.1
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    • pp.21-24
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    • 2005
  • Acute lymphocytic leukemia(ALL) is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow. Currently, only $20-30\%$ of adults with ALL are cured with standard chemotherapy regimens. It is very important risk factor whether to failure to achieve complete remission within 4 weeks or not. The relapse of leukemia is usually classified as hematologic and extramedullary relapse, and extramedullary leukemic infiltration is rarely observed in patients with ALL. In October 2004, a 23-year-old man presented with painless enlargement of both parotid glands. He was diagnosed as ALL(L2 subtype) one month ago, and he gained complete remission with induction chemotherapy. Fine needle aspiration cytology and bone marrow biopsy revealed extramedullary and hemtologic remission. To our knowledge this is the first report of extramedullary relapse in the parotid in ALL.

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Successful remission with L-CHOP for primary mediastinal B-cell lymphoma in a young Maltese dog

  • Chang, Seiyoung;Kim, Hakhyun;Kang, Ji-Houn;Kang, Byeong-Teck;Chang, Dongwoo;Na, Ki-Jeong;Yang, Mhan-Pyo
    • Journal of Biomedical and Translational Research
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    • v.19 no.4
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    • pp.140-145
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    • 2018
  • A one-year-old, intact female, Maltese dog was presented with a history of anorexia and regurgitation. Thoracic radiographs and ultrasonography scans suggested an abnormal mass in the cranial mediastinal region, and computed tomography confirmed the origin of this mass. Ultrasound-guided fine needle aspiration cytology showed the presence of intermediate to large lymphoid cells showing mitotic figures. B-cell lymphoma was confirmed by the result of a polymerase chain reaction assay for antigen receptor rearrangement, therefore the patient was diagnosed with primary mediastinal large B-cell lymphoma (PMBL). The patient underwent L-CHOP (L-asparaginase, cyclophosphamide, doxorubicin, vincristine, prednisolone)-based chemotherapy, and showed complete tumoral remission from the beginning of chemotherapy. Seventytwo weeks after the completion of chemotherapy, the patient is still alive without any evidence of metastasis or relapse. A standardized treatment protocol has yet to be established for primary mediastinal lymphoma in dogs. This case report describes the complete remission of PMBL by an L-CHOP-based chemotherapy protocol in a young Maltese. Clinicians should consider that L-CHOP based chemotherapy may be useful against PMBL in dogs.

A Case of Intrathyroid Thyroglossal Duct Cyst (갑상선 내 갑상설관낭종 1례)

  • Kim, Dae Hwan;Kang, Min Ji;Kim, Jin Pyeong;Lee, Jong Sil;Seo, Ji Hyun;Park, Jung Je
    • International journal of thyroidology
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    • v.11 no.2
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    • pp.167-171
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    • 2018
  • An intrathyroid thyroglossal duct cyst (TGDC) presented as an anterior neck mass in a 62-year-old male without history of prior thyroid disease or infection. This cyst was clinically indistinguishable from a thyroid nodule. In addition to that, fine needle aspiration cytology revealed normal-looking squamous cells. Diagnosis, work-up, management approach, and treatment of intrathyroid TGDC are discussed as well as distinguishing features between intrathyrod TGDC with tract and without tract. This is the very rare case of intrathyroid TGDC in Korean population and the possibility of intrathyroid TGDC should remain in the differential diagnosis of thyroid nodule.

Rectal Prolapse Due to Rectal Polyp Associated with Chronic Eosinophilic Proctitis in a Rex Rabbit

  • Han, Jang-Hee;Ha, Minjong;Ahmed, Sohail;Woo, Sang-Ho;Oh, Jeong-Seop;Yeon, Seong Chan
    • Journal of Veterinary Clinics
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    • v.39 no.2
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    • pp.75-80
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    • 2022
  • An 11-year-old male Rex rabbit (Oryctolagus cuniculus) had a rectal prolapse induced by a polypoid mass. The mass was highly vascularized with a cauliflower-like appearance. Anorectal papilloma was suspected, and fine needle aspiration cytology showed eosinophilic inflammation. After surgical removal of the polyp, postoperative care was given, such as systemic antibiotics and analgesics. In the re-examination, the rabbit was resolved, and there were no complications. Histopathological examination of the removed polyp indicated chronic eosinophilic proctitis to be the cause of the inflammatory condition of the protruding rectal polyp.