Korean Journal of Bronchoesophagology (대한기관식도과학회지)

The Korean Bronchoesophagological Society (대한기관식도과학회)
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An Unusual Case of Acute Lymphocytic Leukemia with Extramedullary Relapse Presenting as Parotid Enlargement

급성 림프구성 백혈병 환자에서 이하선 비대로 나타난 골수외 재발 1례

  • Lee, Dong-Hee (Department of Otolaryngology-HNS, The Catholic University of Korea, College of Medicine) ;
  • Cho, Kwang-Jae (Department of Otolaryngology-HNS, The Catholic University of Korea, College of Medicine)
  • 이동희 (가톨릭대학교 의과대학 이비인후과학교실) ;
  • 조광재 (가톨릭대학교 의과대학 이비인후과학교실)
  • Published : 2005.06.01
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Abstract

Acute lymphocytic leukemia(ALL) is a malignant disease of the bone marrow in which early lymphoid precursors proliferate and replace the normal hematopoietic cells of the marrow. Currently, only $20-30\%$ of adults with ALL are cured with standard chemotherapy regimens. It is very important risk factor whether to failure to achieve complete remission within 4 weeks or not. The relapse of leukemia is usually classified as hematologic and extramedullary relapse, and extramedullary leukemic infiltration is rarely observed in patients with ALL. In October 2004, a 23-year-old man presented with painless enlargement of both parotid glands. He was diagnosed as ALL(L2 subtype) one month ago, and he gained complete remission with induction chemotherapy. Fine needle aspiration cytology and bone marrow biopsy revealed extramedullary and hemtologic remission. To our knowledge this is the first report of extramedullary relapse in the parotid in ALL.

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