A Case of Advanced Thyroid Insular Carcinoma with Invasion of the Sternum

흉골침습을 동반한 진행성 갑상선 섬암종(Insular Carcinoma) 1예

  • Koh Yoon-Woo (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine) ;
  • Lee Seung-Won (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine) ;
  • Lee Jong-Dae (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine) ;
  • Kim Hyo-Jin (Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine) ;
  • Kim Hee-Kyung (Department of Pathology, Soonchunhyang University College of Medicine)
  • 고윤우 (순천향대학교 의과대학 이비인후과학교실) ;
  • 이승원 (순천향대학교 의과대학 이비인후과학교실) ;
  • 이종대 (순천향대학교 의과대학 이비인후과학교실) ;
  • 김효진 (순천향대학교 의과대학 이비인후과학교실) ;
  • 김희경 (순천향대학교 의과대학 병리학교실)
  • Published : 2005.11.01

Abstract

Insular carcinoma(poorly differentiated thyroid cancer) is defined as a aggressive, follicular-derived thyroid carcinoma with behavior intermediate between follicular/papillary and anaplastic carcinomas. It was described by Carcangiu in 1984, but its prognosis, classification and the origin is not yet clear. And preoperative fine needle aspiration cytology of insular carcinoma has not been satisfactory. We experienced a case of advanced thyroid insular carcinoma with invasion of the sternum. So we intend to present the case with a review of the related literatures.

Keywords

References

  1. Carcangiu ML, Zampi G, Rosai J: Poorly differentiated ('insular') thyroid carcinoma. A reinterpretation of Langhans' 'wuchemde Struma'. Am J Surg Pathol. 1984;8:655-668 https://doi.org/10.1097/00000478-198409000-00005
  2. Volante M, Landolfi S, Chiusa L, et al: Poorly differentiated carcinomas of the thyroid with trabecular; insular; and solid patterns: a clinicopathologic study of 183 patients. Cancer. 2004: 100:950-957 https://doi.org/10.1002/cncr.20087
  3. Akslen LA, LiVolsi VA: Poorly differentiated thyroid carcinoma-it is important. Am J Surg Pathol. 2000;24:310-313 https://doi.org/10.1097/00000478-200002000-00031
  4. Rodriguez JM, Parrilla P, Moreno A, et al: Insular carcinoma: an infrequent subtype of thyroid cancer. J Am Coll Surg. 1998; 187:503-508 https://doi.org/10.1016/S1072-7515(98)00233-6
  5. Lee TW, Chung KW, Chang MC, et al: Clinicopathologic Features of Poorly Differentiated (Insular) Carcinoma of Thyroid. J Korean Surg Soc. 2003;64:121-126
  6. Nam SJ, Lee SD, Oh YR, Yang JH: Insular Carcinoma: An Aggressive Subtype of Differentiated Thyroid Neoplasms. J Korean Cancer Assoc. 2000;32:229-234
  7. Choi KU, Kim JY, Lee JS, Lee CH: Fine Needle Aspiration Cytology of Insular Carcinoma of the Thyroid. Korean J Cytopathol. 2003;14:17-21 https://doi.org/10.1046/j.1365-2303.14.s1.1_31.x
  8. Gong Y, Krishnarnurthy S: Fine-needle aspiration of an unusual case of poorly differentiated insular carcinoma of the thyroid. Diagn Cytopathol. 2005;32:103-107 https://doi.org/10.1002/dc.20178
  9. Ashfaq R, Vuitch F, Delgado R, Albores-Saavedra J: Papillary and follicular carcinoma with an insular component. Cancer. 1994; 73:16-23