• Journal of Korean Society of Steel Construction
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• v.18 no.6
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• pp.727-735
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• 2006

In this paper, a geometric nonlinear analysis procedure of the beam-column element including multi-noded cable element in extension of companion paper (Kim et al., 2005) is presented. First, a stiffness matrix was derived about the beam-column element that considers the second effect of the initial force supposing the curved shape at each time-step, with Hermitian polynomials as the shape function. Second, the multi-noded cable element was also subjected to the tangent stiffness matrix. To verify the geometric nonlinearity of this newly developed multi-noded cable-truss element, the Innovative Prestressed Support (IPS) system using this theory was analysed by geometric nonlinear method and the results were compared with those produced by linear analysis.

• Journal of Korea Multimedia Society
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• v.8 no.2
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• pp.201-210
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• 2005

This paper proposes a power efficient 2-dimensional DCT/IDCT architecture driven by input data to be processed. The architecture achieves low power by taking advantage of the typically large fraction of zero and small-valued input processing data in video and image data compression. In particular, it skips multiplication by zero and dynamically activates/deactivates required bit-slices of fine-grain bit partitioned adders within multipliers and accumulators using simple input ANDing and bit-slice MASKing. The processed results from 1-D DCT/IDCT do not have unnecessary sign extension bits (SEBs), which are used for further power reduction in matrix transposer. The results extracted by bit-level transition activity simulations indicate significant power reduction compared to conventional designs.

• Health Policy and Management
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• v.8 no.2
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• pp.110-124
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• 1998

Determining of Strategic Business Units in the organization is a major critical process for improving the organizational performance. On increasing the demands for extension in function of health center, many health centers are trying to provide the various services. But most health center determined the kind and level of service without scientific considerations. The purposes of this study are to develope the model for determination of strategic business units in health center and to test the availability of implementation for it. Our model is rooted from the McKinsey matrix analysis of Product Portfolio Analysis which used widely in marketing field. We modified the evaluation criteria of the McKinsey matrix analysis for health care field appropriately. Our evaluation criteria are categorized into two concepts; contribution of service, availability of service. At first, in terms of contribution of service, market size, market growth rate, needs and demands of regional people, existences of alternative services in that region, correspondence with health policy. The other component, availability of service are included the availability of manpower, financial availability, the level of knowhow on service, acceptance of health care manpower. In the result of analysis, we could conclude that antismoking and antialcoholics education programs, health screening program are important strategically in that aspects of contributions and availability of services. Also, vaccination program is important in that aspect of service availability and diet and exercise program, health library are meaningful in the aspect of service contribution. Therefore, we think that efforts to investigate the evaluation criteria for priority setting or determination of service area in health center are useful challenges.

• KSBB Journal
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• v.23 no.3
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• pp.231-238
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• 2008

The second family member of tissue inhibitors of matrix metalloproteinases, TIMP-2, is a 21kDa protein which inhibits matrix metalloproteinases 2 (MMP-2). Expression of mammalian proteins in E. coli often forms inclusion bodies that are made up of mis-folded or insoluble protein aggregates. The requirement for the formation of 6 disulfide bonds in the process of the TIMP-2 folding is likely to be incompatible with the reducing environment of E. coli. However, this incompatibility can be often overcome by introducing a mutagenesis that could lead to enhancement of the protein solubility. In this reason, we have attempted to express the soluble TIMP-2 in E. coli by applying a modified staggered extension process (StEP), one of the in vitro PCR-based recombinant mutagenesis methods, and error-prone PCR. C-terminally located CAT fusion protein with respect to mutated TIMP-2 proteins enables us to differentiate the soluble TIMP-2 from the insoluble in E. coli by virtue of chloramphenicol resistance. According to this scheme, E. coli harboring properly-folded CAT fused to TIMP-2 protein was selected, and some of the resulting colonies exhibited an enhanced, soluble expression of TIMP-2 compared to the wild type, implying (i) the StEP technique is successfully employed to enhance the proper folding thereby increasing the solubility of TIMP-2, and (ii) the CAT dependent screening may be a simple and effective method to differentiate the soluble protein expression in E. coli.

• Advances in materials Research
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• v.2 no.1
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• pp.37-49
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• 2013

The transition metal salt doped solid polymer electrolyte [TSPE] were prepared with HPMC as a host polymer. The virgin and doped films were prepared by solution-casting method and investigated using wide angle X-ray scattering method. Micro structural parameters like lattice strain (g%), stacking/twin faults, the average number of unit cells counted in a direction perpendicular to the Bragg's plane (hkl) spacing of (hkl) planes dhkl, crystallite size Ds, distortion width, standard deviation were determined by whole pattern powder fitting (WPPF) method, which is an extension of single order method. It is found that the crystallite size decreases with the increase in the content of $FeCl_3$. This decrease is due to increase in localized breaking of polymer network which also accounts for the amorphous nature of the material. The filler inorganic salt $FeCl_3$ acts as plasticizer. FTIR study also confirms and justifies the interaction between the polymer and in-organic salt in the matrix. Physical properties like mechanical stability and Ac conductivity in these films are in conformity with the X-ray results.

• Journal of the Chungcheong Mathematical Society
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• v.25 no.4
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• pp.655-668
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• 2012

An operator $T\;{\varepsilon}\;B(\mathcal{H})$ is said to be $k$-quasi-paranormal operator if $||T^{k+1}x||^2\;{\leq}\;||T^{k+2}x||\;||T^kx||$ for every $x\;{\epsilon}\;\mathcal{H}$, $k$ is a natural number. This class of operators contains the class of paranormal operators and the class of quasi - class A operators. In this paper, using the operator matrix representation of $k$-quasi-paranormal operators which is related to the paranormal operators, we show that every algebraically $k$-quasi-paranormal operator has Bishop's property ($\beta$), which is an extension of the result proved for paranormal operators in [32]. Also we prove that (i) generalized Weyl's theorem holds for $f(T)$ for every $f\;{\epsilon}\;H({\sigma}(T))$; (ii) generalized a - Browder's theorem holds for $f(S)$ for every $S\;{\prec}\;T$ and $f\;{\epsilon}\;H({\sigma}(S))$; (iii) the spectral mapping theorem holds for the B - Weyl spectrum of T.

• Genomics & Informatics
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• v.5 no.4
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• pp.152-160
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• 2007

Most common diseases are caused by multiple genetic and environmental factors. Among the genetic factors, single nucleotide polymorphisms (SNPs) are common DNA sequence variations in individuals and can serve as important genetic markers. Recently, investigations of gene-based and whole genome-based SNPs have been applied to association studies for marker discovery. However, SNPs are so population-specific that the association needs to be verified. Fifty-five genes and 384 SNPs were selected based on association with disease. Genotypes of 337 SNPs in candidate genes were determined using Illumina Sentrix Array Matrix (SAM) chips by an allele-specific extension method in 364 unrelated Korean individuals. Allelic frequencies of SNPs were compared with those of other populations obtained from the International HapMap database. Minor allele frequencies, linkage disequilibrium blocks, tagSNPs, and haplotypes of functional candidate SNPs in 55 genetic disease-associated genes were provided. Our data may provide useful information for the selection of genetic markers for gene-based genetic disease-association studies of the Korean population.

• Journal of KIISE:Computer Systems and Theory
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• v.31 no.3_4
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• pp.187-194
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• 2004

Shear-Warp volume rendering has many advantages such as good image Quality and fast rendering speed. However in the interactive classification environment it has low efficiency of memory access since preprocessed classification is unavailable. In this paper we present an algorithm using the spacial locality of memory access in the interactive classification environment. We propose an extension model appending a rotation matrix to the factorization of viewing transformation, it thus performs a scanline-based rendering in the object and image space. We also show causes and solutions of three problems of the proposed algorithm such as inaccurate front-to-back composition, existence of hole, increasing computational cost. This model is efficient due to the spacial locality of memory access.

• Structural Engineering and Mechanics
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• v.46 no.1
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• pp.19-37
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• 2013

The optimum design of base isolation system considering model parameter uncertainty is usually performed by using the unconditional response of structure obtained by the total probability theory, as the performance index. Though, the probabilistic approach is powerful, it cannot be applied when the maximum possible ranges of variations are known and can be only modelled as uncertain but bounded type. In such cases, the interval analysis method is a viable alternative. The present study focuses on the bounded optimization of base isolation system to mitigate the seismic vibration effect of structures characterized by bounded type system parameters. With this intention in view, the conditional stochastic response quantities are obtained in random vibration framework using the state space formulation. Subsequently, with the aid of matrix perturbation theory using first order Taylor series expansion of dynamic response function and its interval extension, the vibration control problem is transformed to appropriate deterministic optimization problems correspond to a lower bound and upper bound optimum solutions. A lead rubber bearing isolating a multi-storeyed building frame is considered for numerical study to elucidate the proposed bounded optimization procedure and the optimum performance of the isolation system.

• International Journal of Aeronautical and Space Sciences
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• v.12 no.1
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• pp.43-56
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• 2011

An integrated system composed of guidance, navigation and control (GNC) system for autonomous proximity operations and the docking of two spacecraft was developed. The position maneuvers were determined through the integration of the state-dependent Riccati equation formulated from nonlinear relative motion dynamics and relative navigation using rendezvous laser vision (Lidar) and a vision sensor system. In the vision sensor system, a switch between sensors was made along the approach phase in order to provide continuously effective navigation. As an extension of the rendezvous laser vision system, an automated terminal guidance scheme based on the Clohessy-Wiltshire state transition matrix was used to formulate a "V-bar hopping approach" reference trajectory. A proximity operations strategy was then adapted from the approach strategy used with the automated transfer vehicle. The attitude maneuvers, determined from a linear quadratic Gaussian-type control including quaternion based attitude estimation using star trackers or a vision sensor system, provided precise attitude control and robustness under uncertainties in the moments of inertia and external disturbances. These functions were then integrated into an autonomous GNC system that can perform proximity operations and meet all conditions for successful docking. A six-degree of freedom simulation was used to demonstrate the effectiveness of the integrated system.