• Title/Summary/Keyword: expanded method

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Reduced Burst Release from ePTFE Grafts: A New Coating Method for Controlled Drug Release

  • Nam, Hye-Yeong;Kim, Dae-Joong;Lim, Hyun-Jung;Lee, Byung-Ha;Baek, In-Su;Park, Sang-Hun;Park, Jong-Sang
    • Bulletin of the Korean Chemical Society
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    • v.29 no.2
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    • pp.422-426
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    • 2008
  • Hemodialysis graft coated with paclitaxel prevents stenosis; however, large initial burst release of paclitaxel causes many negative effects such as drug toxicity and inefficient drug loss. Therefore we developed and tested a novel coating method, double dipping, to provide controlled and sustained release of paclitaxel locally. Expanded polytetrafluoroethylene (ePTFE) grafts were dipped twice into a solution of several different paclitaxel concentrations. In vitro release tests of the double dipping method showed that early burst release could be somewhat retarded and followed by sustained release for a long time. We observed the effect of paclitaxel coating by double dipping in porcine model of arterio-venous (AV) grafts between the common carotid artery and the external jugular vein. 12 weeks after constructing AV grafts, cross sections of the graft venous anastomosis were obtained and analyzed. Paclitaxel coated ePTFE grafts by double dipping were observed to prevent neointimal hyperplasia and therefore reduced stenosis of the arteriovenous hemodialysis grafts, especially at the graft venous anastomosis sites. Our results demonstrate that second dipping of ePTFE graft, which was already coated once with paclitaxel, washes off the drug on a surface of the graft and affects the ratio of paclitaxel on the surface to that of the inner space, possibly by diffusion: thus the early burst of drug can be somewhat reduced.

The Study of Industrial Clusters in the Busan, Ulsan, Koungnam as Southeast Area of Korea Analysed by the Location Quotient(LQ) Analysis Method (한국 조선산업 연구: 산업클러스터 특화분석 중심으로)

  • Lee, Sang-Yun
    • Journal of Korea Technology Innovation Society
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    • v.14 no.3
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    • pp.599-621
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    • 2011
  • The role of local economies in pursuing national economic development has expanded with greater influence. So a number of countries have adopted industrial cluster policies for regional and national economic development. Korean government, by the same token, puts emphasis on industrial cluster policies. But the academic studies on the necessities and effects of industrial clusters for Korean shipbuilding industry have been carried out little in Korean due to the lack of empirical studies on Korean industrial clusters. So this study focuses on analysing the industrial clusters in the Busan, Ulsan, Koungnam as southeast area of Korea. To be more specific, this study intends to provide answers to the following question: Are there industrial clusters in the Busan, Ulsan, Koungnam as southeast area of Korea analysed by the Location Quotient(LQ) analysis method? And as a consequence, Shipbuilding industrial clusters of southeast area of Korea were not identified.

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A Study on TE Scattering by a Conductive Strip Grating Between a Double Dielectric Layer (2중 유전체층 사이의 완전도체띠 격자구조에 의한 TE 산란에 관한 연구)

  • Yoon, Uei-Joong
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.17 no.2
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    • pp.83-88
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    • 2017
  • In this paper, TE(transverse electric) scattering problems by a conductive strip grating between a double dielectric layer are analyzed by applying the PMM(point matching method) known as a numerical method of electromagnetic fileld. The boundary conditions are applied to obtain the unknown field coefficients, the scattered electromagnetic fields are expanded in a series of Floquet mode functions, and the conductive boundary condition is applied to analysis of the conductive strip. The numerical results for the normalized reflected and transmitted power are analyzed by according as the width and spacing of conductive strip, the relative permittivity and thickness of the double dielectric layers, and incident angles. The most normalized reflected powers of the sharp variations in minimum values are scattered in direction of the other angles except incident angle. The numerical results for the presented structure of this paper are shown in good agreement compared to those of the existing papers.

Enhancing Document Clustering using Important Term of Cluster and Wikipedia (군집의 중요 용어와 위키피디아를 이용한 문서군집 향상)

  • Park, Sun;Lee, Yeon-Woo;Jeong, Min-A;Lee, Seong-Ro
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.49 no.2
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    • pp.45-52
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    • 2012
  • This paper proposes a new enhancing document clustering method using the important terms of cluster and the wikipedia. The proposed method can well represent the concept of cluster topics by means of selecting the important terms in cluster by the semantic features of NMF. It can solve the problem of "bags of words" to be not considered the meaningful relationships between documents and clusters, which expands the important terms of cluster by using of the synonyms of wikipedia. Also, it can improve the quality of document clustering which uses the expanded cluster important terms to refine the initial cluster by re-clustering. The experimental results demonstrate that the proposed method achieves better performance than other document clustering methods.

A Design of Noise Reduction Circuit for A radio Telephonic System (무선전화 시스템용 잡음억제회로의 설계)

  • Moon, Jong-Kyu;Kim, Duk-Gyoo
    • Journal of the Institute of Electronics Engineers of Korea TE
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    • v.39 no.2
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    • pp.84-89
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    • 2002
  • In this paper, we present the design method of noise reduction circuit in telephonic system. The circuit consists of compressor, expander and a filter. The basic idea of a proposed method compresses the audible signal in order to mask the channel noise during transmission and then expand at the reverse rate the transmitted signal to naturally recover the original signal. Of course, there should be no distortion or other degradation of the audio itself in passing through companding(compress/expand) cycle. In the compressing process, the gain of compressor is automatically controlled by the envelope level of input signal in order to increase the effective dynamic range of input signal and to improve the signal to noise ratio. The compressed rate is the root time of a audible signal. The compressed signal should be expanded at the square time of the signal to recover a original signal. Simulation shows the proposed method improves the performance of the noise reduction of a channel noise as well as stability. 

Selection of Optimum Ratio of 3 Components (Ir-Sn-Sb) Electrode using Design of Mixture Experiments (혼합물 실험계획법을 이용한 3성분(Ir-Sn-Sb) 전극의 최적비율 선정)

  • Park, Young-Seek
    • Journal of Environmental Science International
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    • v.25 no.5
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    • pp.737-744
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    • 2016
  • For electrolysis process using an insoluble electrode, electrochemical performance was greatly affected by the manufacturing method and procedure, such as the firing temperature, pre-treatment, type of precursor solution, coating method, electrode material, etc. Components of the electrode therein is one of the most important factors in electrochemical reaction. To achieve such characteristics, a appropriate ratio of the electrode material should be carefully chosen. The aim of this research was to apply experimental design method in the optimization of electrode component for the maximum generation of oxidants in electrochemical oxidation process. Mixture design, especially expanded simplex lattice design, in DOME (design of mixture experiments) with Design Expert - commercial software - was used to analyze the data. Analysis of variance (ANOVA) showed a high coefficient of determination ($R^2$) value of 0.9470, thus ensuring a satisfactory adjustment of the $3^{rd}$ order special cubic regression model with the experimental data. The application of response surface methodology (RSM) yielded the following regression equation, which is an empirical relationship between the TRO generation concentration and independent variables(mol ratio of 3 electrode components) in a real unit: TRO generation concentration $(mg/L)=TRO\;conc.=98.25{\times}[Ir]+49.71{\times}[Sn]+95.29{\times}[Sb]-16.91{\times}[Ir]{\times}[Sn]-29.47{\times}[Ir]{\times}[Sb]-22.65{\times}[Sn]{\times}[Sb]+703.19{\times}[Ir]{\times}[Sn]{\times}[Sb]$. The optimized formulation of the 3 component electrode for an high TRO (total residual oxidants) generation was acquired at mol ratio of Ir 0.406, Sn 0.210, Sb 0.384 (desirability d value, 1).

Visualized Execution Analyzer for the Java Class File (자바 클래스 파일에 대한 시각화 실행 분석기)

  • Ko, Kwang-Man
    • The KIPS Transactions:PartA
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    • v.11A no.5
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    • pp.319-324
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    • 2004
  • The Java language is rapidly being adopted in the Internet. The distributed applications and their application range are being expanded beyond just a programing language and developed Into software applications. A variety of researches are going on with regard to the Java Virtual Machine runtime environment and methods of analyzing the Java class files and utilizing the information for applications. A class file is a converted file that is executable by the Java virtual machine. Analysis on the class file structure and the runtime processes will be convenient in arranging the decompilers and debugging the source programs. This paper is about the runtime process analyzer that presents the runtime processes, including class files, more visually. The content of a class file will be easily accessed and expressed as in a graphic user interface. The information in the class file displayed is divided into Constant_Pool, Class_file, Interface, Field, Method and Attribute with information on method area, operand stack and local variables expressed visually.

A Study on the Variable Password Generation Method in Internet Authentication System (변동형 비밀번호 생성방법 및 이를 이용한 인터넷 인증 시스템에 관한 연구)

  • Kang, Jung-Ha;Kim, Jae Young;Kim, Eun-Gi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.3
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    • pp.1409-1415
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    • 2013
  • With the development of Internet communication and the use of a variety of online services has been greatly expanded. Therefore, the importance of authentication techniques for users of online services has increased. The most commonly used methods for user authentication is a technique that utilizes a prearranged password. However, the existing password scheme for authentication must use the same password every time. Therefore, the password being leaked by attackers, it can be used maliciously. In this paper, we proposed the Variable Password Generation Method in Internet Authentication System that generates a new password using information such as the access date, time, and IP address when user logs in. The method proposed in this paper prevents disclosure of personal information due to password exposure and improves the reliability and competitiveness in the field of security systems.

Analysis of the TE Scattering by a Resistive Strip Grating Over a Grounded Dielectric Plane (접지된 유전체 평면위의 저항띠 격자구조에 의한 TE 산란 해석)

  • Yoon, Uei-Joong
    • Journal of Advanced Navigation Technology
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    • v.10 no.3
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    • pp.198-204
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    • 2006
  • In this paper, TE(transverse electric) scattering problems by a resistive strip grating on a grounded dielectric plane according to the strip width and grating period, the relative permittivity and thickness of dielectric layer, and incident angles of a TE plane wave are analyzed by applying the FGMM(Fourier-Galerkin Moment Method) known as a numerical procedure. The induced surface current density is simply expanded in a Fourier series by using the exponential function as a simple function. The reflected power gets increased according as the relative permittivity and thickness of dielectric multilayers gets increased, the sharp variations of the reflected power are due to resonance effects were previously called wood's anomallies[7]. To verify the validity of the proposed method, the numerical results of normalized reflected power for the uniform resistivity R = 0 as a conductive strip case show in good agreement with those in the existing paper.

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Efficient Image Stitching Using Fast Feature Descriptor Extraction and Matching (빠른 특징점 기술자 추출 및 정합을 이용한 효율적인 이미지 스티칭 기법)

  • Rhee, Sang-Burm
    • KIPS Transactions on Software and Data Engineering
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    • v.2 no.1
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    • pp.65-70
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    • 2013
  • Recently, the field of computer vision has been actively researched through digital image which can be easily generated as the development and expansion of digital camera technology. Especially, research that extracts and utilizes the feature in image has been actively carried out. The image stitching is a method that creates the high resolution image using features extract and match. Image stitching can be widely used in military and medical purposes as well as in variety fields of real life. In this paper, we have proposed efficient image stitching method using fast feature descriptor extraction and matching based on SURF algorithm. It can be accurately, and quickly found matching point by reduction of dimension of feature descriptor. The feature descriptor is generated by classifying of unnecessary minutiae in extracted features. To reduce the computational time and efficient match feature, we have reduced dimension of the descriptor and expanded orientation window. In our results, the processing time of feature matching and image stitching are faster than previous algorithms, and also that method can make natural-looking stitched image.