• Title/Summary/Keyword: existence solution

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Detection of PspA by Interdigitated Nanogap Devices

  • Park, Jimin;Park, Dae Keun;Lee, Cho Yeon;Kang, Aeyeon;Oh, Jihye;Kim, Gyuhee;Lee, Sangho;Yun, Wan Soo
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.268.2-268.2
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    • 2013
  • Nanogap interdigitated electrodes (NIDEs) can serve as an alternative platform for the biomolecular detection [1]. In this work, the NIDEs were adopted in a simple and sensitive detection of Pneumococcal surface protein A (PspA). The NIDEs were fabricated by the combination of photo and chemical lithography. Photolithographically-defined initial gap of about 200 nm was narrowed down to a few tens of nanometers by surface-initiated growth of the initial electrodes (chemical lithography) [2]. Bare silicon oxide surface between the electrodes was chemically modified to immobilize capturing antibodies and, after exposure to the samples, the device was immersed in a solution containing the probe-antibody-conjugated Au nanoparticles (Au NPs). The conductance change accompanied with the Au NP immobilization was interpreted as the existence of PspA. Detection limit of the measurements and further improvement of the detection efficiency were discussed with the results from I-V analysis, scanning electron microscopy, and atomic force microscopy.

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Preparation and Characterization of Surface Capped CdSe Nanoparticles from an Aqueous Solution (수용액으로부터 표면 수식된 CdSe 나노 입자의 제조 및 특성)

  • Kim, Shin-Ho;Lee, Yoon-Bok;Kim, Yong-Jin;Kim, Yang-Do;Kim, In-Bae
    • Korean Journal of Materials Research
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    • v.16 no.11
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    • pp.663-667
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    • 2006
  • CTAB(cetyltrimethylammonium bromide)-capped CdSe nanoparticles were prepared by using a 4 : 1(v/v) distilled water-isopropyl alcohol mixture. The cadmium chloride and sodium selenosulfate were used as the cadmium and selenium source. By the analysis of XRD and XPS, the resultant particle was confirmed to be cubic CdSe phase. TEM image showed CdSe nanoparticles with empty core. The CTAB-capped sample showed an maximum absorption at 418nm, blue-shifting compared with bulk CdSe, which indicated stronger quantum confinement effect compared with uncapped sample. From FT-IR analysis, it was found that the presence of the new peaks in the $850{\sim}1250cm^{-1}$ range indicated the existence of chemical bonding between CTAB and surface of CdSe nanoparticles. Also TG analysis indicated that there were two weight-loss steps for the CTAB-capped CdSe nanoparticles. It was suggested that CTAB played a significant role in protecting CdSe nanoparticles.

Dialetheism and the Sorites Paradox (양진주의와 더미 역설)

  • Lee, Jinhee
    • Korean Journal of Logic
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    • v.22 no.1
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    • pp.87-124
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    • 2019
  • A dialetheic approach to the sorites paradox is to understand a borderline case as a true contradiction. In order to accommodate this approach, the possibility of an alternative that does not involve a contradiction should be considered first. Beall presents an alternative that has all virtues of dialetheic solution without contradiction. I do not think his alternative has no contradiction. Using the inclosure schema I will show it. Furthermore, I will show that all alternatives which do not accept the existence of cut-off point imply a contradiction. This means that we have to accept a true contradiction as long as we accept the intuition of vagueness, especially, what is called 'tolerance'.

Effect of bidirectional internal flow on fluid.structure interaction dynamics of conveying marine riser model subject to shear current

  • Chen, Zheng-Shou;Kim, Wu-Joan
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.4 no.1
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    • pp.57-70
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    • 2012
  • This article presents a numerical investigation concerning the effect of two kinds of axially progressing internal flows (namely, upward and downward) on fluid.structure interaction (FSI) dynamics about a marine riser model which is subject to external shear current. The CAE technology behind the current research is a proposed FSI solution, which combines structural analysis software with CFD technology together. Efficiency validation for the CFD software was carried out first. It has been proved that the result from numerical simulations agrees well with the observation from relating model test cases in which the fluidity of internal flow is ignorable. After verifying the numerical code accuracy, simulations are conducted to study the vibration response that attributes to the internal progressive flow. It is found that the existence of internal flow does play an important role in determining the vibration mode (/dominant frequency) and the magnitude of instantaneous vibration amplitude. Since asymmetric curvature along the riser span emerges in the case of external shear current, the centrifugal and Coriolis accelerations owing to up- and downward internal progressive flows play different roles in determining the fluid.structure interaction response. The discrepancy between them becomes distinct, when the velocity ratio of internal flow against external shear current is relatively high.

Chromosome-Centric Human Proteome Study of Chromosome 11 Team

  • Hwang, Heeyoun;Kim, Jin Young;Yoo, Jong Shin
    • Mass Spectrometry Letters
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    • v.12 no.3
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    • pp.60-65
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    • 2021
  • As a part of the Chromosome-centric Human Proteome Project (C-HPP), we have developed a few algorithms for accurate identification of missing proteins, alternative splicing variants, single amino acid variants, and characterization of function unannotated proteins. We have found missing proteins, novel and known ASVs, and SAAVs using LC-MS/MS data from human brain and olfactory epithelial tissue, where we validated their existence using synthetic peptides. According to the neXtProt database, the number of missing proteins in chromosome 11 shows a decreasing pattern. The development of genomic and transcriptomic sequencing techniques make the number of protein variants in chromosome 11 tremendously increase. We developed a web solution named as SAAvpedia for identification and function annotation of SAAVs, and the SAAV information is automatically transformed into the neXtProt web page using REST API service. For the 73 uPE1 in chromosome 11, we have studied the function annotaion of CCDC90B (NX_Q9GZT6), SMAP (NX_O00193), and C11orf52 (NX_Q96A22).

A Study on the Educational Implications of Zeno's Paradoxes through Philosophical Investigation (제논의 역설에 대한 철학적 검토를 통한 교육적 시사점 고찰)

  • Baek, Seung Ju;Choi, Younggi
    • Journal for History of Mathematics
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    • v.33 no.6
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    • pp.327-343
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    • 2020
  • This study investigate philosophical discussions related to the Zeno's paradoxes in order to derive the mathematics educational implications. The paradox of Zeno's motion is sometimes explained by the calculus theories. However, various philosophical discussions show that the resolution of Zeno's paradox by calculus is not a real solution, and the concept of a continuum which is composed of points and the real number continuum may not coincide with the physical space and time. This is supported by the fact that the hyperreal number system of nonstandard analysis could be another model of a straight line or time and that an alternative explanation of Zeno's paradox was possible by the hyperreal number system. The existence of two different theories of the continuum suggests that teachers and students may not have the same view of the continuum. It is also suggested that the real world model used in school mathematics may not necessarily match the student's intuition or mathematical practice, and that the real world application of mathematics theory should be emphasized in education as a kind of 'correspondence.'

A Study on BEM-Based Numerical Simulation Technique for Underwater Explosions (수중 폭발 시뮬레이션을 위한 경계 요소법 기반의 수치 해석 기법 연구)

  • Choung, Joonmo;Lee, Jae-bin
    • Journal of the Society of Naval Architects of Korea
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    • v.57 no.5
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    • pp.271-277
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    • 2020
  • Recoverability and vulnerability of navy ships under underwater explosion are critical verification factors in the acquisition phase of navy ships. This paper aims to establish numerical analysis techniques for the underwater explosion of navy ships. Doubly Asymptotic Approach (DAA) Equation of Motion (EOM) of primary shock wave and secondary bubble pulse proposed by Geers-Hunter was introduced. Assuming a non-compressive fluid, reference solution of the DAA EOM of Geers-Hunter using Runge-Kutta method was derived for the secondary bubble pulse phase with an assumed charge conditions. Convergence analyses to determine fluid element size were performed, suggesting that the minimum fluid element size for underwater explosion analysis was 0.1 m. The spherical and cylindrical fluid domains were found to be appropriate for the underwater explosion analyses from the fluid domain shape study. Because the element size of 0.1 m was too small to be applied to the actual navy ships, a very slender beam with the square solid section was selected for the study of fluid domain existence effect. The two underwater explosion models with/without fluid domain provided very similar results in terms of the displacement and stress processes.

Ecological and Economic Aspects of Innovative Development of Urban Logistics Infrastructure Taking Considering Pandemic Constraints

  • Rusanova, Svitlana;Kuzkin, Olexiy;Melkonov, Hryhorii;Lavrushchenko, Yuliana;Kuzmenko, Oksana;Zhurian, Viktoriia
    • International Journal of Computer Science & Network Security
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    • v.22 no.3
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    • pp.9-16
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    • 2022
  • The relevance of the topic is determined by the existence of inconsistencies between economic and environmental aspects of innovative development of urban logistics infrastructure, as well as the conflict of public, state and private commercial interests in this issue. The purpose of the article is to determine the principles and effective tools for innovative development of urban logistics infrastructure, taking into account pandemic constraints. The influence of the environmental aspect on the dynamics of transport flows was analyzed in detail and characterized, the scheme of determining the optimal solution for the development of the city was proposed considering the compromise between economic and ecological interests of society, state and business entities. A scheme of innovative development of urban logistics infrastructure under pandemic constraints was also developed. Materials of the article are relevant for developers of city plans, managers of urban logistics infrastructure, employees of enterprises participating in transport and logistics markets, scientists, and doctoral students.

POSITIVE SOLUTIONS FOR A NONLINEAR MATRIX EQUATION USING FIXED POINT RESULTS IN EXTENDED BRANCIARI b-DISTANCE SPACES

  • Reena, Jain;Hemant Kumar, Nashine;J.K., Kim
    • Nonlinear Functional Analysis and Applications
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    • v.27 no.4
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    • pp.709-730
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    • 2022
  • We consider the nonlinear matrix equation (NMEs) of the form 𝓤 = 𝓠 + Σki=1 𝓐*iℏ(𝓤)𝓐i, where 𝓠 is n × n Hermitian positive definite matrices (HPDS), 𝓐1, 𝓐2, . . . , 𝓐m are n × n matrices, and ~ is a nonlinear self-mappings of the set of all Hermitian matrices which are continuous in the trace norm. We discuss a sufficient condition ensuring the existence of a unique positive definite solution of a given NME and demonstrate this sufficient condition for a NME 𝓤 = 𝓠 + 𝓐*1(𝓤2/900)𝓐1 + 𝓐*2(𝓤2/900)𝓐2 + 𝓐*3(𝓤2/900)𝓐3. In order to do this, we define 𝓕𝓖w-contractive conditions and derive fixed points results based on aforesaid contractive condition for a mapping in extended Branciari b-metric distance followed by two suitable examples. In addition, we introduce weak well-posed property, weak limit shadowing property and generalized Ulam-Hyers stability in the underlying space and related results.

Optimal control formulation in the sense of Caputo derivatives: Solution of hereditary properties of inter and intra cells

  • Muzamal Hussain;Saima Akram;Mohamed A. Khadimallah;Madeeha Tahir;Shabir Ahmad;Mohammed Alsaigh;Abdelouahed Tounsi
    • Steel and Composite Structures
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    • v.48 no.6
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    • pp.611-623
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    • 2023
  • This work considered an optimal control formulation in the sense of Caputo derivatives. The optimality of the fractional optimal control problem. The tumor immune interaction in fractional form provides an excellent tool for the description of memory and hereditary properties of inter and intra cells. So the interaction between effector-cells, tumor cells and are modeled by using the definition of Caputo fractional order derivative that provides the system with long-time memory and gives extra degree of freedom. In addiltion, existence and local stability of fixed points are investigated for discrete model. Moreover, in order to achieve more efficient computational results of fractional-order system, a discretization process is performed to obtain its discrete counterpart. Our technique likewise allows the advancement of results, such as return time to baseline that are unrealistic with current model solvers.