• 한국임상수의학회지
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• 제14권1호
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• pp.136-139
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• 1997

A retrospective study on 72 dogs with demodicosis, presented to Veterinary Teaching Hospital of Chonnam National University between 1987 and 1996, is reported. About 18% of the dogs with skin disease had demodicosis. About 75% of the patients with demodicosis were purebred dogs, and the short-haired breeds had a much higher incidence than do long-haired breeds. The age of the patient ranged from 1 month to 3 years, and about 63% of the patients were less than a year of age. Sex and seasons have been shown to have no effect on the development of demodicosis. A hereditary predisposition of generalized demodicosis has been observed from an affected litter.

• 한국임상수의학회지
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• 제38권4호
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• pp.169-173
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• 2021

A 10-year-old castrated male Shih-tzu dog presented with a history of generalized demodicosis, refractory to conventional therapy with ivermectin and amitraz for a year. The patient was also diagnosed with concurrent deep pyoderma, Malassezia dermatitis, and otitis externa. Treatment with amoxicillin-clavulanate, antifungal drugs (itraconazole, miconazole), and milbemycin oxime resulted in a good response for 90 days. Approximately 4 months later, the first relapse of demodicosis occurred and the miticidal therapy was changed to ivermectin. Additional diagnostic tests were performed to investigate an underlying cause for the recurrence of demodicosis, and endocrinopathies and allergic dermatitis were excluded based on the results. Although ivermectin therapy was sustained for 440 days, a second relapse occurred and amitraz baths were added to the therapy. Despite this therapy, the demodicosis persisted, and the miticidal therapy was changed to oral fluralaner, which led to rapid resolution. Demodicosis did not recur again before death approximately 920 days after administration of oral fluralaner. This case report describes the complete resolution of refractory demodicosis using oral fluralaner in a dog.

• 한국동물위생학회지
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• 제28권1호
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• pp.39-47
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• 2005

A survey on the prevalence of heartworms, scabies and demodicosis of 1,011 pet dogs in 5 animal hospitals Jeonju area was peformed from June to October 2004. The result obtained from this experiment were summarized as follows; 1. The 1,011 pet dogs coming to help the animal hospital more than disease of pleonephritis 62($6.1\%$), enteritis 75($7.4\%$), dermatitis 62($6.1\%$), scabies 55($5.4\%$), heartworms 43($4.3\%$), tympanitis 41($4.1\%$), demodicosis 22($2.2\%$), gastritis 21($2.2\%$), fracture 9($0.9\%$), respectively. 2. The 307 examined pet dogs were heartworms antigen positive to 43($14.0\%$), Microfilaria 31($10.1\%$) and the kinds of mixed breeds 34 (antigen and Microfilaria 12), Jindo 19 (antigen 7, Microfilaria 6), respectively. 3. Heartworms antigen positive of examined 34 pet dogs mean ages 4.3 and general blood cell count mean of WBC $20.5{\times}10^3/mm^3$, RBC $61.3{\times}10^6/mm^3$ HGB $6.27g/d{\ell}$ HCT $20.9\%$, PLT $13.0{\times}10^3/mm^3$, MCV $33.2{\mu}m^3$, MCH 39.4pg, MCHC $14.8g/d{\ell}$, RDW $280.1\%$, MPV $9.2{\mu}m^3$, respectively. but showed a few high normal value WBC, MCV, MCH and a low MCHC. 4. This experiment was 1,011 pet dogs to dermatitis 139($13.7\%$) of scabies 55($39.6\%$), demodicosis 22($15.8\%$), respectively.

• 대한수의학회지
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• 제32권3호
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• pp.407-412
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• 1992

In order to obtain basic data concerning the treatment of canine demodicosis, 8 Doberman Pinschers were infected with Demodex canis. The clinical signs, were examined after infection, and their hematological and blood chemical values were determined, along with four non-infected control dogs of same breed. The number of white blood cells, especially the number of band neutrophils was significantly higher(p<0.01) in the infected than in the non-infected control dogs. This result indicated that the first episode of secondary infection should be treated with an appropriate antibiotics based on the culture and sensitivity test. The red blood cell counts, packed cell volume, hemoglobin contents, and serum albumin levels were significantly lower (p<0.01~0.001) in the infected than in the non-infected control dogs. These results suggested that the infected dogs had an anemia due to malnutrition. Thus, the infected dogs should be on a well balanced, high protein diet.

• 한국임상수의학회지
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• 제24권3호
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• pp.432-436
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• 2007

개 모낭충증의 새로운 치료법을 확립하기 위하여 항생제의 약침과 일반 치료의 병행을 이용한 치료 효과를 조사하였다. 본 연구에서는 모낭충으로 진단된 개 3두를 이용하였다. Enrofloxacin의 약침을 폐수(BL13) 위중(BL40), 대추(GV14), 족삼리(ST36), 합곡(LI04), 곡지(LI11) 및 삼음교(SP06)의 혈위에 각각 5주간 실시하였다. 또한 일반 치료법인 invermectin과 0.05% amitraz 약욕을 5주간 추가로 실시하였다. 소양증, 찰과상, 홍반 및 탈모와 같은 임상증상은 약침과 일반치료에 의해서 치료 전에 비하여 현저하게 완화되었다. Case 1은 4주 후에 완치되었고, case 2는 5주 후에 증상이 약간 잔존하였으며, 그리고 case 3은 5주 후에 완치되었다. 혈중 백혈구 수는 치료와 더불어 모든 케이스에서 감소하는 경향을 보였으나, 호중구/림프구 비율은 일정한 경향을 나타내지 않았다. 5주째 병리조직 검사 소견상에서 case 1과 case 3은 뚜렷한 병리조직학적 변화가 관찰되지 않았으나, case 2는 경도의 변화가 관찰되었다. 결론적으로 개 모낭충에 이환된 본 환축들은 항생제 약침과 일반 치료법의 병행으로 양호한 치료반응을 나타낸 증례이었다.

• 한국임상수의학회지
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• 제15권1호
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• pp.209-213
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• 1998

난치성 전신성 모낭충증에 감염되어 약 4개월간 모낭충 치료제인 amitraz(0.0125%) 처치에도 불구하고 치유되지 않은 한국산 풍산개 2두에 대한 ivermectin 및 amitraz 의 병용치료효과를 알아보았다. 전신성 모낭충증은 신체의 50% 또는 4개의 발에 모두 모낭충 이 검출된 것으로 정의하였다. 내원시 신체검사, 심장사상충검사 및 최소 裂訃위에 대한 피부 박리검사를 실시하여 모낭충을 진단하였고 치료는 돼지용 ivermectin을 체중 kg당 0.5 mg을 피하로 매일 주사하였으며 1주일에 2회 amitraz 약욕을 실시하였다. 피부농피중은 cephalexin 20 mg/kg을 경구로 일일 2회 투여하여 치료하였다. 치료후 4주에 피부병변이 치유되기 시 작하였으며 6주에는 탈모 및 소수의 발진을 제외하고는 피부병변이 정상으로 회복하였다. 피 부박리검사는 6주에 모낭충이 검출되지 않았다. 이들 제제에 의한 부작용은 관찰되지 않았으며 매일 ivermectin 투여와 amitraz 약욕치료의 병용치료는 amitraz로 치료가 되지 않는 난치성의 전신성 모낭충증에 대한 치료기간을 단축시키는 효과적인 치료방법으로 생각된다.

• Parasites, Hosts and Diseases
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• 제60권6호
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• pp.429-432
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• 2022

Inflammatory eyelid symptoms are common in primary care and there have been several reports on Demodex blepharitis. In the present study, we evaluate the 9 patients with Demodex blepharitis, who showed inflammation of the eyelids, dry eye, and cylindrical dandruff at the base of the eyelashes. The causative species from all patients was Demodex folliculorum of either the adult or nymph stage. Two patients had recurrent chalazion and 3 patients had keratitis. Weekly lid scrubs with 50% tee tree oil were performed for 6 weeks. After treatment, the symptoms of blepharitis and keratitis had improved in all patients. This case report provides clinical reference source for the proper treatment of ocular demodicosis.

• 한국임상수의학회지
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• 제37권2호
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• pp.96-99
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• 2020

An 11-year-old female Yorkshire terrier presented with alopecia, hyperpigmentation, and pruritus. Dermatological examination revealed a large number of Demodex mites including D. cornei and D. canis. Mean length of total body length of D. cornei was one third shorter than that of D. canis. In addition, sequential analysis of DNA extracted from the skin lesions showed a 97% and 99% identity with the two sequences of D. canis and D. cornei. This is the first report of a combined infestation of D. cornei and D. canis in Korea, along with its morphological and molecular characterization.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2007년도 춘계학술대회
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• pp.124-124
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• 2007

• 대한수의사회지
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• 제30권9호
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• pp.559-565
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• 1994

A one-year-old female Korean dog was referred to our department with a week history of generalized bald patches. On physical examination, general weakness, lethargy, loss of appetite were noted. Skin findings were confluent erythematous scaly bald patches