Li, Cong;Cai, Wentao;Liu, Shuli;Zhou, Chenghao;Cao, Mingyue;Yin, Hongwei;Sun, Dongxiao;Zhang, Shengli;Loor, Juan J.
Asian-Australasian Journal of Animal Sciences
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v.33
no.11
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pp.1725-1731
/
2020
Objective: An initial RNA-Sequencing study revealed that UDP-galactose-4-epimerase (GALE) was one of the most promising candidates for milk protein concentration in Chinese Holstein cattle. This enzyme catalyzes the interconversion of UDP-galactose and UDP-glucose, an important step in galactose catabolism. To further validate the genetic effect of GALE on milk protein traits, genetic variations were identified, and genotypes-phenotypes associations were performed. Methods: The entire coding region and the 5'-regulatory region (5'-UTR) of GALE were re-sequenced using pooled DNA of 17 unrelated sires. Association studies for five milk production traits were performed using a mixed linear animal model with a population encompassing 1,027 Chinese Holstein cows. Results: A total of three variants in GALE were identified, including two novel variants (g.2114 A>G and g.2037 G>A) in the 5'-UTR and one previously reported variant (g.3836 G>C) in an intron. All three single nucleotide polymorphisms (SNPs) were associated with milk yield (p<0.0001), fat yield (p = 0.0006 to <0.0001), protein yield (p = 0.0232 to <0.0001) and protein percentage (p<0.0001), while no significant associations were detected between the SNPs and fat percentage. A strong linkage disequilibrium (D' = 0.96 to 1.00) was observed among all three SNPs, and a 5 Kb haplotype block involving three main haplotypes with GAG, AGC, and AGG was formed. The results of haplotype association analyses were consistent with the results of single locus association analysis (p<0.0001). The phenotypic variance ratio above 3.00% was observed for milk protein yield that was explained by SNP-g.3836G >C. Conclusion: Overall, our findings provided new insights into the polymorphic variations in bovine GALE gene and their associations with milk protein concentration. The data indicate their potential uses for marker-assisted breeding or genetic selection schemes.
There are increasing numbers of North Korean defectors. Many of them enter universities and major in social welfare in order to get jobs. As a required course, they must participate in field practicum and many difficulties are expected. This study aims to examine the North Korean defectors' practicum experience in specific, and to support more effectively in the field work education. To achieve this purpose, female North Korean defectors who go to G cyber university and have finished their field practicums, were interviewed in an in-depth interview. The data were analyzed with the open coding through the constant comparison method as Grounded theory's initial analysis. As the result, the following was found: 49 concepts, 18 sub-categories, and 7 categories. The categories include difficulties in the process of preparation for and beginning with various obstacles; confusion due to the differences between the North Korean and South Korean culture; tasks and functions that were not expected, personal relationships which were burdensome to them; feeling a lack of professional competence; inevitable environmental circumstances, and personal problems. Based on the results, suggestions for better support in field practice education in the side of universities, community agencies, individual students and the general society were addressed.
Recently, the smart applications, such as smart phone and smart TV, become a hot issue in IT consumer markets. In particular, the smart TV provides 3D video services, hence efficient coding methods for 3D video data are required. Three-dimensional (3D) video involves stereoscopic or multi-view images to provide depth experience through 3D display systems. Binocular cues are perceived by rendering proper viewpoint images obtained at slightly different view angles. Since the number of viewpoints of the multi-view video is limited, 3D display devices should generate arbitrary viewpoint images using available adjacent view images. In this paper, after we explain a view synthesis method briefly, we propose a new algorithm to compensate view synthesis errors around object boundaries. We describe a 3D warping technique exploiting the depth map for viewpoint shifting and a hole filling method using multi-view images. Then, we propose an algorithm to remove boundary noises that are generated due to mismatches of object edges in the color and depth images. The proposed method reduces annoying boundary noises near object edges by replacing erroneous textures with alternative textures from the other reference image. Using the proposed method, we can generate perceptually inproved images for 3D video systems.
Hong, Mee-Suk;Kim, Hye-Kyung;Shin, Dong-Hoon;Song, Dae-Kyu;Ban, Ju Yeon;Kim, Bum Shik;Chung, Joo-Ho
Molecular & Cellular Toxicology
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v.4
no.4
/
pp.318-322
/
2008
Obesity is an increasing worldwide health problem that is strongly related to the imbalance of food intake and energy metabolism. It was well-known that several substances in the hypothalamus regulate food intake and energy metabolism. We planned an integrative study to elucidate the mechanism of the development of obesity. Firstly, to find candidate genes with the marvelous effect, the different expression in the hypothalamus between ob/ob and 48-h fasting mice was investigated by using DNA microarray technology. As a result, we found 3 genes [peroxisome proliferator activated receptor, gamma, coactivator 1 alpha (Ppargc1a), calmodulin 1 (Calm1), and complexin 2 (Cplx2)] showing the different hypothalamic expression between ob/ob and 48-h fasting mice. Secondly, a genetic approach on PPARGC1A gene was performed, because PPARGC1A acts as a transcriptional coactivator and a metabolic regulator. Two hundred forty three obese female patients with body mass index (BMI)${\geq}$25 and 285 control female subjects with BMI 18 to<23 were recruited according to the Classification of Korean Society for the Study of Obesity. Among the coding single nucleotide polymorphisms (cSNPs) of PPARGC1A, 2 missense SNPs (rs8192678, Gly482Ser; rs3736265, Thr612Met) and 1 synonymous SNP (rs3755863, Thr528Thr) were selected, and analyzed by PCR-RFLP and pyrosequencing. For the analysis of genetic data, chi-square ($X^2$) test and EH program were used. The rs8192678 was significantly associated with obese women (P<0.0006; odds ratio, 1.5327; 95% confidence interval, 1.2006-1.9568). Haplotypes also showed significant association with obese women ($X^2$=33.28, P<0.0008). These results suggest that PPARGC1A might be related to the development of obesity.
Objectives: The purpose of the study was to investigate the content analysis of daily tooth cleaning service records by caregivers in a long-term care facility. Methods: The data were analyzed by qualitative research based on content analysis of the daily records of the processes and results of daily tooth cleaning service. Twenty caregivers provided tooth, gum and denture cleaning service after breakfast, lunch, and dinner to 48 elderly residents. The study lasted about two weeks(from August 4 to August 20, 2014). The researcher reconstructed the language by repeatedly reviewing the caregivers statements in the records. The content categories were derived from the records through a reiterative manual comparative analysis. Using constant comparison method, reconstructed meanings were incorporated into various meanings and reanalyzed by final categories called as analytic coding. In order to validate the reliability, 6 times of discussion made the common meanings through a master's degree student and a dental hygiene professor. Results: The caregivers identified lack of understanding and ability to recognize the functional physical and mental changes in the elderly. The elderly had difficulty in recognizing silent communication and daily tooth cleaning. The caregivers were so strenuous in taking care of the daily tooth cleaning service for the elderly. At last, they gave up the daily tooth cleaning service and took on it to the guardians. They found that there was no social supporting network for oral health of the elderly residents. Conclusions: Caregivers had insufficient understanding of the functional physical and mental changes in the elderly residents, and they had difficulty providing daily tooth cleaning service to the elderly due to poor skill and abilities.
Journal of The Korean Association For Science Education
/
v.35
no.5
/
pp.919-929
/
2015
This study aims to develop a modeling-based learning program about geologic structures and to reveal the relationship between the argumentation patterns and levels of students' mental models. Participants included 126 second grade high school students in four sessions of modeling-based learning regarding continental drift, oceanic ridges, transform faults, and characteristics of faults. A modeling-based learning program was implemented in two classes of the experimental group, and teacher-centered traditional classes were carried out for the other students in the comparison group. Science achievement scores and the distribution of students' mental models in experimental and comparison groups were quantitatively compared. The video-taped transcripts of five teams' argumentation were qualitatively analyzed based on the analytic framework developed in the study. The analytic framework for coding students' argumentation in the modeling-based learning was composed of five components of TAP and the corresponding components containing alternative concepts. The results suggest that the frequencies of causal two-dimensional model and cubic model were high in the experimental group, while the frequencies of simple two-dimensional model and simple cross sectional model were high in the comparison group. The higher the frequency of claims, an argumentation pattern was proven successful, and the level of mental model was higher. After the rebuttal was suggested, students observed the model again and claimed again according to new data. Therefore, the model could be confirmed as having a positive impact on students' argumentation process.
Kim, Nam-Jin;Seo, Dong-Hoan;Lee, Sung-Geun;Shin, Chang-Mok;Cho, Kyu-Bo;Kim, Soo-Joong
Korean Journal of Optics and Photonics
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v.17
no.3
/
pp.231-239
/
2006
In recent years, a hierarchical security architecture has been widely studied because it can efficiently protect information by allowing an authorized user access to the level of information. However, the conventional hierarchical decryption methods require several decryption keys for the high level information. In this paper, we propose a hierarchical image encryption using random phase masks and Walsh code having orthogonal characteristics. To decrypt the hierarchical level images by only one decryption key, we combine Walsh code into the hierarchical level system. For encryption process, we first perform a Fourier transform for the multiplication results of the original image and the random phase mask, and then expand the transformed pattern to be the same size and shape of Walsh code. The expanded pattern is finally encrypted by multiplying with the Walsh code image and the binary phase mask. We generate several encryption images as the same encryption process. The reconstruction image is detected on a CCD plane by a despread process and Fourier transform for the multiplication result of encryption image and hierarchical decryption keys which are generated by Walsh code and binary random phase image. Computer simulations demonstrate that the proposed technique can decrypt hierarchical information by using only one level decryption key image and it has a good robustness to the data loss such as random cropping.
Journal of the Institute of Electronics Engineers of Korea SP
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v.42
no.5
s.305
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pp.173-180
/
2005
In this paper, we proposed the image hiding method which decreases calculation amount by encrypt partial data using discrete wavelet transform(DWT) and linear scale quantization which were adopted as the main technique for frequency transform in JPEG2000 standard. Also we used the chaotic system and cat map which has smaller calculation amount than other encryption algorithms and then dramatically decreased calculation amount. This method operates encryption process between quantization and entropy coding for preserving compression ratio of images and uses the subband selection method. Also, suggested encryption method to JPEG2000 progressive transmission. The experiments have been performed with the Proposed methods implemented in software for about 500 images. Consequently, we are sure that the proposed is efficient image encryption methods to acquire the high encryption effect with small amount of encryption. It has been shown that there exits a relation of trade-off between the execution time and the effect of the encryption. It means that the proposed methods can be selectively used according to the application areas.
Journal of the Institute of Electronics Engineers of Korea SP
/
v.49
no.1
/
pp.19-30
/
2012
For digital data compression, the quantization is the main part of the lossy source coding. In order to improve the performance of quantization, the vector quantizer(VQ) can be employed. The encoding complexity, however, exponentially increases as the vector dimension or bit rate gets large. Much research has been conducted to alleviate such problems of VQ. Especially for high bit rates, a constrained VQ, which is called the sample-adaptive product quantizer(SAPQ), has been proposed for reducing the hugh encoding complexity of regular VQs. SAPQ has very similar structure as to the product VQ(PQ). However, the quantizer performance can be better than the PQ case. Further, the encoding complexity and the memory requirement for the codebooks are lower than the regular full-search VQ case. Among SAPQs, 1-SAPQ has a simple quantizer structure, where each product codebook is symmetric with respect to the diagonal line in the underlying vector space. It is known that 1-SAPQ shows a good performance for i.i.d. sources. In this paper, a study on designing 1-SAPQ for the first-order Markov process. For an efficient design of 1-SAPQ, an algorithm for the initial codebook is proposed, and through the numerical analysis it is shown that 1-SAPQ shows better quantizer distortion than the VQ case, of which encoding complexity is similar to that of 1-SAPQ, and shows distortions, which are close to that of the DPCM(differential pulse coded modulation) scheme with the Lloyd-Max quantizer.
KIPS Transactions on Software and Data Engineering
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v.2
no.8
/
pp.517-526
/
2013
When developing an android mobile application the androids intent is used as a mechanism to send messages between local equipment of androids application inner part and other applications. But the androids intent does not support sending messages via each android products intent. If there is a way to support each androids equipments to send messages, it will be easier to make non-stopping services. Non-stopping service is used when the user is using the android to do word or searching services and suddenly changes to a different android product but still maintains the progress what was currently being done without waiting the programs to be loaded. It is possible to send messages to each android products by using the socket, but the connection must be maintained stably which is the weak point. In this paper, I am suggesting a BRIF(Broadcasting Remote Intent Framework) framework to send messages to different android products. BRIF is a framework that uses the Googles C2DM service which services asynchronous transmissions to different android products. This is organized with the C2DM server, RemoteContext Api, web server and RISP(Remote Intent Service Provider) which is will be easy to be used for the developers since there are no big changes for coding compared to the intent code.
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