• 한방안이비인후피부과학회지
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• 제33권4호
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• pp.100-113
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• 2020

Objectives : The purpose of this study is to analyze the trend of Korean medical treatments on contact dermatitis. Methods : Based on NDSL, OASIS, RISS, KTKP, KISS, KCI with the keyword 'Contact Dermatitis', published in 2001-2020.06.10., total 12 studies have been found and analyzed. Results : Out of 1,046 articles searched, 12 papers were selected. All of those were case-study. Herb medicine, acupuncture, pharmacopuncture, externals, other treatments were used as treatment for contact dermatitis. All of research which selected have reported that the Korean medical treatment was effective. Conclusions : According to the results, Korean medical treatments can be effective treatment for contact dermatitis. Further clinical studies are expected using evaluation methods to analyze the results and to establish high level of evidence.

• Toxicological Research
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• 제26권2호
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• pp.123-130
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• 2010

The effect of DHU001, a mixed herbal formula consisted of 7 types aqueous extracts for various respiratory disorders were evaluated on 2,4-dinitrofluorobenzene (DNFB)-induced contact dermatitis, type I allergic model. Contact dermatitis was induced by sensitization with dinitrophenyl-derivatized ovalbumin (DNP-OVA) and DNFB challenge as antigen. Two different dosages of DHU001 (300 and 150 mg/kg) were orally administered to DNP-OVA sensitization mice once a day for 7 days with reference material, dexamethasone (15 mg/kg, intraperitoneal treatment). End of 7 days oral administration of DHU001 extracts or intraperitoneal treatment of dexamethasone, the changes on the edematous changes and scratching behavior were measured. Immediate after DNFB challenge on ear or paw of DNP-OVA sensitized mice, increases of ear and paw thicknesses and weights were detected with anterior ear skin (dermis to epidermis) thickness and paw scratching behavior increases. However, these contact dermatitis signs induced by DNFB treatment were reduced by treatment of the both different dosages of DHU001 and dexamethasone, respectively. The results obtained in this study suggest that oral treatment of DHU001 extracts also has relatively favorable effects on contact dermatitis.

• 한방안이비인후피부과학회지
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• 제18권3호
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• pp.44-54
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• 2005

Background and Objectives: Allergic contact dermatitis is a common environmental health issue and seriously affect the patient's quality of life. The more our environment industrialized, the number of material that could cause the allergic contact dermatitis has been increased, consequently the prevalence of allergic contact dermatitis has been increased. In oriental medicine, clinically Chogam-Tang has been used fur the treatment of allergic dermatitis, eczema, atopic dermatitis etc. The objective of this study is to investigate the effects of Chogam-Tang on allergic contact dermatitis Meterial and Methods: Fifteen Sprague-Dawley rats were divided into three groups: normal, control, experimental group. Control and experimental group were induced allergic contact dermatitis, by DNCB. Experimental group was orally administered the Chogam-Tang. Each group was observed after 24, 48 and 72 hours. Contact hypersensitivity assay, melanin-erythema measurement, pH measurement skin moisture measurement and biopsy were performed. Results: 1. In contact hypersensitivity assay, experimental group showed decreased ear swelling compared with control group at 48hours. 2. ln melanin measurement there was no difference in three groups. 3. In erythema measurement experimental group showed reduction at 48. 72 hours. 4. In pH measurement, experimental group and control group showed increase in pH but there was no statistical significance. 5. In skin moisture measurement, experimental group showed higher skin moisture level than control group at 24 hours and showed lower skin moisture level at 72 hours, but there was no statistical significance. 6. In biopsy, experimental group showed decrement of Iymphocyte as time goes by, and regeneration of keratin layer was increased compared with normal group. Conclusions: Chogam-Tang shows anti-inflammatory effect in biopsy, improves hydration levels of skin, decreases erythema level on allergic contact dermatitis.

• 혜화의학회지
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• 제20권2호
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• pp.125-131
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• 2012

알레르기성 접촉 피부염을 진단 받고 양방치료를 받았으나 별무 호전하던 환자에게 침치료와 양격산가감방을 복용하여 약 2개월간 증상이 초기보다 증상이 완화되는 효과가 있었다. 그러나 약물 치료를 배제하고 침치료만 시행하던 중 환자가 상열감 및 소양감은 거의 소실되었으나 홍조 증상이 정체 양상을 보였고 이에 저자는 치료후기를 혈조 상태로 변증하고 환자의 환부에 경피적외선조사요법을 시행하여 정체중이던 안면홍조 상태가 최근 약 1달간 10회의 치료로 환자가 만족할만한 효과가 있었다.

• 대한본초학회지
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• 제28권6호
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• pp.25-29
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• 2013

Objectives : The dried root of Sophora flavescens Aiton have been used to treat patient with skin diseases such as eczema in Eastern countries. S. flavescens can clear away heat and dry dampness and purge sthenic-fire from the liver and gallbladder. Recently, anti-allergic effect of S. flavescens has been reported. However, the effect on skin condition of contact dermatitis still remains unknown. Thus, the purpose of this study is to evaluate the efficacy of S. flavescens on contact dermatitis. Methods : In order to investigate the effects of S. flavescens (methanol extract of S. flavescens, MESR) on skin condition, the contact dermatitis was induced in mice skin by using 1-fluoro-2,4-dinitrofluorobenzene (DNFB). As the effective endpoints, skin thickness, skin weight, histopathological change were checked. In addition, effects on skin lesion, body weight and spleen/body weight ratio were also investigated. Results : Topical application of MESR ($500{\mu}g/day$) lowered skin thickness (P < 0.05) and skin weight (P < 0.05), respectively. MESR-treated group showed diminished spongiosis and immune cell infiltration in skin tissues compared to those of non-treated control group. The inhibition of skin lesions was also observed in MESR-treated group. In addition, MESR did not affect body weight gain and spleen/body weight ratio in contrast with those in dexamethasone-treated group. Conclusion : These data suggest that Sophorae Radix could improve skin lesion of contact dermatitis. This indicates the possibility for Sophorae Radix to be used to patients with skin diseases such as contact dermatitis.

• 성인간호학회지
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• 제19권4호
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• pp.634-643
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• 2007

Purpose: This study was performed to investigate the type and frequency of end colostomy-related complications and to identify the risk factors for those complications. Methods: Retrospective analysis of medical records was made in 708 patients who underwent end colostomy in Samsung Medical Center between October 1994 and February 2005. The type was divided into stomal and peristomal complications: stomal complications included bleeding, necrosis, mucocutaneous separation, prolapsed stoma, retraced stoma, stenosis, and hyperplasia; peristomal complications did peristomal varix, peristomal hernia, irritant contact dermatitis, allergic contact dermatitis, maceration, folliculitis, hyperplasia, bacterial infection, candidal infection, malignancy in the peristomal area, mechanical damage and pyoderma gangrenosum. Results: For stomal complications, hyperplasia was most common(9.0%). For peristomal complications, irritant contact dermatitis was developed in 17.4%. Sex and BMI were risk factors for irritant contact dermatitis, hyperplasia, peristomal hernia, flat stoma, and retracted stoma. Conclusion: Teaching for preventing irritant contact dermatitis such as proper pouching and peristomal skin protection, and for comprehensive weight control should be emphasized on self care program for ostomates, while ostomy care nurse should take a careful consideration of preoperative ostomy site marking in female obese patients.

• 한방안이비인후피부과학회지
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• 제29권4호
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• pp.169-181
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• 2016

Objectives : The purpose of this case report is to know the effect of Korean medical treatments on occupational contact dermatitis. Methods : We reported 2 cases who visited Allergy and Derma-Cosmetic Clinic of Kyung Hee University Hospital at Gangdong. They were diagnosed with occupational contact dermatitis and treated by Korean medical treatment. Results : One patient recovered after 13 days of admission and total 9 months of outpatient period. Another patient recovered after 9 days of admission and total 7 months of outpatients period through Korean Medical Treatment. Conclusions : We may expect that Korean medical treatment had therapeutic effects on occupational contact dermatitis, but the additional study will be conducted for revealing the exact therapeutic effects.

• 한방안이비인후피부과학회지
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• 제27권4호
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• pp.209-220
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• 2014

홍반과 소양감을 주증으로 하는 모르타르로 인한 직업성 알레르기성 접촉성 피부염 환자 1례에서 한약치료, 침 치료, 약침치료 및 외치요법 등의 한방치료만으로 양호한 치료효과를 확인하여 이를 보고하는 바이다.

• 사상체질의학회지
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• 제34권4호
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• pp.68-80
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• 2022

Objectives This study is to report a significant improvement in a Taeeumin patient with systemic contact dermatitis after eating urushiol chicken by herbal medicine treatment. Methods The patient had complaints of erythema, swelling, pruritus, scaly skin, and facial flushing. We treated the patient with an herbal medicine 'Galgeunhaegi-tang' for three months. We evaluated the treatment outcome of systemic contact dermatitis using the Three Item Severity(TIS) score every visit and facial flushing by Image color summarizer at the first and last visit. Results After the treatment, the severity of the patient's skin complaints lessened from moderate to mild. The Image color summarizer showed a minor decrease in the normalized red color level and a significant increase in the brightness level and facial color percentage. Conclusions The patient diagnosed with systemic contact dermatitis, treated with Galgeunhaegi-tang for three months, showed a significant improvement in skin complaints with brighter and even facial color.

• 대한피부과학회지
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• 제56권9호
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• pp.571-572
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• 2018